| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
A mosaic activating mutation in AKT1 associated with the Proteus syndrome.
|
N Engl J Med
|
2011
|
8.26
|
|
2
|
A critical role for IL-21 in regulating immunoglobulin production.
|
Science
|
2002
|
7.09
|
|
3
|
SAP-controlled T-B cell interactions underlie germinal centre formation.
|
Nature
|
2008
|
5.14
|
|
4
|
Follicular helper T cells are required for systemic autoimmunity.
|
J Exp Med
|
2009
|
4.25
|
|
5
|
SAP is required for generating long-term humoral immunity.
|
Nature
|
2003
|
3.85
|
|
6
|
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.
|
Science
|
2005
|
3.65
|
|
7
|
Regulation of NKT cell development by SAP, the protein defective in XLP.
|
Nat Med
|
2005
|
3.62
|
|
8
|
Regulation of microRNA expression and abundance during lymphopoiesis.
|
Immunity
|
2010
|
3.29
|
|
9
|
Early Th1 cell differentiation is marked by a Tfh cell-like transition.
|
Immunity
|
2011
|
3.24
|
|
10
|
Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha.
|
Immunity
|
2011
|
3.06
|
|
11
|
Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84.
|
Immunity
|
2010
|
3.00
|
|
12
|
A role for thymic stromal lymphopoietin in CD4(+) T cell development.
|
J Exp Med
|
2004
|
2.81
|
|
13
|
Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.
|
Immunity
|
2010
|
2.79
|
|
14
|
Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.
|
Immunity
|
2006
|
2.77
|
|
15
|
Tec family kinases in T lymphocyte development and function.
|
Annu Rev Immunol
|
2005
|
2.76
|
|
16
|
SLAM family receptors and SAP adaptors in immunity.
|
Annu Rev Immunol
|
2011
|
2.52
|
|
17
|
Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase.
|
Immunity
|
2009
|
2.51
|
|
18
|
Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.
|
Immunity
|
2013
|
2.37
|
|
19
|
The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1).
|
J Exp Med
|
2009
|
2.34
|
|
20
|
The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development.
|
Immunity
|
2012
|
2.19
|
|
21
|
SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1.
|
Immunity
|
2004
|
2.18
|
|
22
|
Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.
|
PLoS Genet
|
2010
|
2.14
|
|
23
|
SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation.
|
J Exp Med
|
2006
|
1.92
|
|
24
|
Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation.
|
Nat Cell Biol
|
2003
|
1.92
|
|
25
|
Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells.
|
Immunity
|
2011
|
1.83
|
|
26
|
Improved generation of C57BL/6J mouse embryonic stem cells in a defined serum-free media.
|
Genesis
|
2004
|
1.79
|
|
27
|
The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death.
|
Nat Immunol
|
2008
|
1.73
|
|
28
|
TNF-alpha is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.
|
J Clin Invest
|
2004
|
1.63
|
|
29
|
Requirements for selection of conventional and innate T lymphocyte lineages.
|
Immunity
|
2007
|
1.59
|
|
30
|
Molecular and cellular pathogenesis of X-linked lymphoproliferative disease.
|
Immunol Rev
|
2005
|
1.57
|
|
31
|
Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton.
|
J Immunol
|
2005
|
1.54
|
|
32
|
SH2D1A regulates T-dependent humoral autoimmunity.
|
J Exp Med
|
2004
|
1.51
|
|
33
|
Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP.
|
Curr Biol
|
2003
|
1.47
|
|
34
|
T-cell signaling regulated by the Tec family kinase, Itk.
|
Cold Spring Harb Perspect Biol
|
2010
|
1.45
|
|
35
|
Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production.
|
Blood
|
2010
|
1.44
|
|
36
|
Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome.
|
Clin Immunol
|
2007
|
1.40
|
|
37
|
Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk.
|
Immunol Rev
|
2009
|
1.32
|
|
38
|
Functional hierarchy of the N-terminal tyrosines of SLP-76.
|
J Immunol
|
2006
|
1.29
|
|
39
|
Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia.
|
Proc Natl Acad Sci U S A
|
2006
|
1.21
|
|
40
|
Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis.
|
Immunity
|
2012
|
1.20
|
|
41
|
TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans.
|
J Clin Invest
|
2009
|
1.20
|
|
42
|
SAP is required for Th cell function and for immunity to influenza.
|
J Immunol
|
2006
|
1.18
|
|
43
|
Requirement for Tec kinases in chemokine-induced migration and activation of Cdc42 and Rac.
|
Curr Biol
|
2004
|
1.17
|
|
44
|
Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells.
|
J Exp Med
|
2014
|
1.16
|
|
45
|
T follicular helper cell diversity and plasticity.
|
Trends Immunol
|
2013
|
1.14
|
|
46
|
Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein.
|
Blood
|
2010
|
1.14
|
|
47
|
Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses.
|
J Immunol
|
2008
|
1.11
|
|
48
|
Tec kinases, actin, and cell adhesion.
|
Immunol Rev
|
2007
|
1.09
|
|
49
|
Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.
|
J Immunol
|
2010
|
1.06
|
|
50
|
Rheumatologic and autoimmune manifestations of primary immunodeficiency disorders.
|
Curr Opin Rheumatol
|
2009
|
1.06
|
|
51
|
Beyond calcium: new signaling pathways for Tec family kinases.
|
J Cell Sci
|
2002
|
1.05
|
|
52
|
Selective targeting of ITK blocks multiple steps of HIV replication.
|
Proc Natl Acad Sci U S A
|
2008
|
1.04
|
|
53
|
Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program.
|
J Immunol
|
2014
|
1.03
|
|
54
|
Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion.
|
J Immunol
|
2005
|
1.01
|
|
55
|
A BAC contig map of the Ly49 gene cluster in 129 mice reveals extensive differences in gene content relative to C57BL/6 mice.
|
Genomics
|
2002
|
1.00
|
|
56
|
A novel ICOS-independent, but CD28- and SAP-dependent, pathway of T cell-dependent, polysaccharide-specific humoral immunity in response to intact Streptococcus pneumoniae versus pneumococcal conjugate vaccine.
|
J Immunol
|
2008
|
0.99
|
|
57
|
The expression of Wiskott-Aldrich syndrome protein (WASP) is dependent on WASP-interacting protein (WIP).
|
Int Immunol
|
2007
|
0.96
|
|
58
|
Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates.
|
FEBS J
|
2011
|
0.94
|
|
59
|
The murine NK receptor 2B4 (CD244) exhibits inhibitory function independent of signaling lymphocytic activation molecule-associated protein expression.
|
J Immunol
|
2004
|
0.92
|
|
60
|
A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes.
|
J Immunol
|
2013
|
0.91
|
|
61
|
Advantages of q-PCR as a method of screening for gene targeting in mammalian cells using conventional and whole BAC-based constructs.
|
Nucleic Acids Res
|
2008
|
0.90
|
|
62
|
The human condition: an immunological perspective.
|
Nat Immunol
|
2011
|
0.88
|
|
63
|
Tec kinases: shaping T-cell activation through actin.
|
Trends Cell Biol
|
2004
|
0.88
|
|
64
|
Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP).
|
Cell Immunol
|
2009
|
0.88
|
|
65
|
Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells.
|
Proc Natl Acad Sci U S A
|
2012
|
0.88
|
|
66
|
CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus.
|
Blood
|
2006
|
0.87
|
|
67
|
Characterization of Ly108 in the thymus: evidence for distinct properties of a novel form of Ly108.
|
J Immunol
|
2012
|
0.86
|
|
68
|
Perturbation of B cell activation in SLAM-associated protein-deficient mice is associated with changes in gammaherpesvirus latency reservoirs.
|
J Immunol
|
2007
|
0.86
|
|
69
|
Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.
|
J Biol Chem
|
2008
|
0.84
|
|
70
|
Cellular and molecular requirements for the selection of in vitro-generated CD8 T cells reveal a role for Notch.
|
J Immunol
|
2013
|
0.84
|
|
71
|
Lymph node choreography: B cells take the lead.
|
Nat Immunol
|
2012
|
0.81
|
|
72
|
T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice.
|
Eur J Immunol
|
2014
|
0.80
|
|
73
|
Fine-tuning lymphocyte regulation: what's new with tyrosine kinases and phosphatases?
|
Curr Opin Immunol
|
2004
|
0.79
|
|
74
|
Acinar cell apoptosis in Serpini2-deficient mice models pancreatic insufficiency.
|
PLoS Genet
|
2005
|
0.78
|
|
75
|
To B or not to B.
|
Blood
|
2010
|
0.75
|
|
76
|
Ncking BCR-mediated PI3K activation.
|
EMBO Rep
|
2013
|
0.75
|