Published in Rev Sci Instrum on April 01, 2008
The physics of cancer: the role of physical interactions and mechanical forces in metastasis. Nat Rev Cancer (2011) 3.42
Engineering microscale topographies to control the cell-substrate interface. Biomaterials (2012) 1.51
Substrate stiffness increases twitch power of neonatal cardiomyocytes in correlation with changes in myofibril structure and intracellular calcium. Biophys J (2011) 1.34
Fibroblasts and myofibroblasts in wound healing: force generation and measurement. J Tissue Viability (2009) 1.22
Mechanical coupling between myofibroblasts and cardiomyocytes slows electric conduction in fibrotic cell monolayers. Circulation (2011) 1.10
Platelet retraction force measurements using flexible post force sensors. Lab Chip (2010) 0.95
Application of sensing techniques to cellular force measurement. Sensors (Basel) (2010) 0.89
Probing cellular traction forces with magnetic nanowires and microfabricated force sensor arrays. Nanotechnology (2012) 0.86
Mechanobiology of platelets: techniques to study the role of fluid flow and platelet retraction forces at the micro- and nano-scale. Int J Mol Sci (2011) 0.83
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Mechanotransduction in intervertebral discs. J Cell Mol Med (2014) 0.75
Spatial and temporal coordination of traction forces in one-dimensional cell migration. Cell Adh Migr (2016) 0.75
Tissue cells feel and respond to the stiffness of their substrate. Science (2005) 23.42
Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates. Nat Cell Biol (2001) 14.08
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Cell movement is guided by the rigidity of the substrate. Biophys J (2000) 13.84
Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proc Natl Acad Sci U S A (2003) 11.53
Local force and geometry sensing regulate cell functions. Nat Rev Mol Cell Biol (2006) 11.29
Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk. Nat Rev Mol Cell Biol (2001) 10.74
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Silicone rubber substrata: a new wrinkle in the study of cell locomotion. Science (1980) 9.81
Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J Cell Biol (2001) 9.73
The relationship between force and focal complex development. J Cell Biol (2002) 6.26
Force mapping in epithelial cell migration. Proc Natl Acad Sci U S A (2005) 5.08
Traction forces generated by locomoting keratocytes. J Cell Biol (1994) 4.97
Visualizing the mechanical activation of Src. Nature (2005) 4.63
Mechanobiology and diseases of mechanotransduction. Ann Med (2003) 3.86
Imaging the traction stresses exerted by locomoting cells with the elastic substratum method. Biophys J (1996) 3.63
Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize. Curr Opin Cell Biol (2006) 3.21
Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways. Trends Cell Biol (2006) 3.07
Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci (2006) 2.98
Flexible substrata for the detection of cellular traction forces. Trends Cell Biol (2002) 2.62
Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins. Sci STKE (2002) 2.36
Cell mechanics and mechanotransduction: pathways, probes, and physiology. Am J Physiol Cell Physiol (2004) 2.32
Simple approach to micropattern cells on common culture substrates by tuning substrate wettability. Tissue Eng (2004) 2.13
Magnetic microposts as an approach to apply forces to living cells. Proc Natl Acad Sci U S A (2007) 2.10
Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. Am J Physiol Cell Physiol (2003) 2.09
The role of actin-binding protein 280 in integrin-dependent mechanoprotection. J Biol Chem (1998) 1.89
Nanotechnology for cell-substrate interactions. Ann Biomed Eng (2006) 1.87
Single cell mechanotransduction and its modulation analyzed by atomic force microscope indentation. Biophys J (2002) 1.86
Shear force at the cell-matrix interface: enhanced analysis for microfabricated post array detectors. Mech Chem Biosyst (2005) 1.63
Microfabricated silicone elastomeric post arrays for measuring traction forces of adherent cells. Methods Cell Biol (2007) 1.56
Tensile stress stimulates microtubule outgrowth in living cells. J Cell Sci (2002) 1.30
Isostaticity and controlled force transmission in the cytoskeleton: A model awaiting experimental evidence. Biophys J (2006) 0.91
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell (2004) 16.89
Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proc Natl Acad Sci U S A (2003) 11.53
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature (2010) 6.25
Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell (2009) 5.43
Emergent patterns of growth controlled by multicellular form and mechanics. Proc Natl Acad Sci U S A (2005) 5.22
Mechanical regulation of cell function with geometrically modulated elastomeric substrates. Nat Methods (2010) 4.74
Mechanotransduction in development: a growing role for contractility. Nat Rev Mol Cell Biol (2009) 4.10
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. Nat Mater (2012) 4.10
Mechanical tugging force regulates the size of cell-cell junctions. Proc Natl Acad Sci U S A (2010) 3.44
Measurement of mechanical tractions exerted by cells in three-dimensional matrices. Nat Methods (2010) 3.35
Versatile, fully automated, microfluidic cell culture system. Anal Chem (2007) 3.19
Nanopattern-induced changes in morphology and motility of smooth muscle cells. Biomaterials (2005) 2.94
Deconstructing the third dimension: how 3D culture microenvironments alter cellular cues. J Cell Sci (2012) 2.89
Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels. Nat Mater (2013) 2.84
Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid. Nat Med (2006) 2.78
Emergence of patterned stem cell differentiation within multicellular structures. Stem Cells (2008) 2.34
Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus. J Biomed Mater Res A (2003) 2.17
Simple approach to micropattern cells on common culture substrates by tuning substrate wettability. Tissue Eng (2004) 2.13
Magnetic microposts as an approach to apply forces to living cells. Proc Natl Acad Sci U S A (2007) 2.10
Stem cell shape regulates a chondrogenic versus myogenic fate through Rac1 and N-cadherin. Stem Cells (2010) 2.09
An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling. J Cell Biol (2006) 2.08
Cell polarity triggered by cell-cell adhesion via E-cadherin. J Cell Sci (2009) 2.04
Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr Biol (2013) 2.02
Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA. Mol Biol Cell (2004) 1.98
A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Eng Part A (2012) 1.95
Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues. Proc Natl Acad Sci U S A (2009) 1.89
Nanotechnology for cell-substrate interactions. Ann Biomed Eng (2006) 1.87
Cell shape and substrate rigidity both regulate cell stiffness. Biophys J (2011) 1.86
Bioactive hydrogels made from step-growth derived PEG-peptide macromers. Biomaterials (2010) 1.80
Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition. Mol Biol Cell (2012) 1.80
A hitchhiker's guide to mechanobiology. Dev Cell (2011) 1.72
Cell-cell signaling by direct contact increases cell proliferation via a PI3K-dependent signal. FEBS Lett (2002) 1.70
Cytoskeleton-based forecasting of stem cell lineage fates. Proc Natl Acad Sci U S A (2009) 1.68
Shear force at the cell-matrix interface: enhanced analysis for microfabricated post array detectors. Mech Chem Biosyst (2005) 1.63
Activation of ROCK by RhoA is regulated by cell adhesion, shape, and cytoskeletal tension. Exp Cell Res (2007) 1.63
E-cadherin engagement stimulates proliferation via Rac1. J Cell Biol (2006) 1.61
Assaying stem cell mechanobiology on microfabricated elastomeric substrates with geometrically modulated rigidity. Nat Protoc (2011) 1.60
Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions. Proc Natl Acad Sci U S A (2012) 1.59
Microfabricated silicone elastomeric post arrays for measuring traction forces of adherent cells. Methods Cell Biol (2007) 1.56
Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment. Annu Rev Biophys (2012) 1.55
Engineering cellular microenvironments to improve cell-based drug testing. Drug Discov Today (2002) 1.54
Cell traction forces direct fibronectin matrix assembly. Biophys J (2009) 1.54
How vinculin regulates force transmission. Proc Natl Acad Sci U S A (2013) 1.51
Myofibrillar architecture in engineered cardiac myocytes. Circ Res (2008) 1.48
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro. Proc Natl Acad Sci U S A (2013) 1.44
Bone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension. Stem Cells Dev (2011) 1.40
Fabrication of aligned microstructures with a single elastomeric stamp. Proc Natl Acad Sci U S A (2002) 1.38
Optimization of yield in magnetic cell separations using nickel nanowires of different lengths. Biotechnol Prog (2005) 1.37
Resveratrol protects human lens epithelial cells against H2O2-induced oxidative stress by increasing catalase, SOD-1, and HO-1 expression. Mol Vis (2010) 1.35
Cadherins, RhoA, and Rac1 are differentially required for stretch-mediated proliferation in endothelial versus smooth muscle cells. Circ Res (2007) 1.35
Geometrically controlled endothelial tubulogenesis in micropatterned gels. Tissue Eng Part A (2010) 1.33
Design and formulation of functional pluripotent stem cell-derived cardiac microtissues. Proc Natl Acad Sci U S A (2013) 1.29
Formation and optogenetic control of engineered 3D skeletal muscle bioactuators. Lab Chip (2012) 1.28
Cellular and multicellular form and function. Adv Drug Deliv Rev (2007) 1.24
VE-cadherin simultaneously stimulates and inhibits cell proliferation by altering cytoskeletal structure and tension. J Cell Sci (2003) 1.23
MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status. J Mol Med (Berl) (2011) 1.21
Geometric control of vascular networks to enhance engineered tissue integration and function. Proc Natl Acad Sci U S A (2013) 1.19
Facile modification of collagen directed by collagen mimetic peptides. J Am Chem Soc (2005) 1.19
Endothelial cell sensing of flow direction. Arterioscler Thromb Vasc Biol (2013) 1.17
Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion. J Cell Sci (2008) 1.17
Bioresponsive mesoporous silica nanoparticles for triggered drug release. J Am Chem Soc (2011) 1.15
Dielectrophoretic registration of living cells to a microelectrode array. Biosens Bioelectron (2004) 1.14
Assembly of multicellular constructs and microarrays of cells using magnetic nanowires. Lab Chip (2005) 1.13
Dielectrophoretic registration of living cells to a microelectrode array. Biosens Bioelectron (2004) 1.10
Characterization of the nuclear deformation caused by changes in endothelial cell shape. J Biomech Eng (2004) 1.10
Mechanical coupling between myofibroblasts and cardiomyocytes slows electric conduction in fibrotic cell monolayers. Circulation (2011) 1.10
Immobilization of growth factors on collagen scaffolds mediated by polyanionic collagen mimetic peptides and its effect on endothelial cell morphogenesis. Biomacromolecules (2008) 1.10
Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. Biomaterials (2013) 1.05
Cell adhesion and mechanical stimulation in the regulation of mesenchymal stem cell differentiation. J Cell Mol Med (2013) 1.05
Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2012) 1.04
Subcellular spatial segregation of integrin subtypes by patterned multicomponent surfaces. Integr Biol (Camb) (2011) 1.03
Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells. Proc Natl Acad Sci U S A (2011) 1.02
Decoupling cell and matrix mechanics in engineered microtissues using magnetically actuated microcantilevers. Adv Mater (2013) 1.01
Fibrous hyaluronic acid hydrogels that direct MSC chondrogenesis through mechanical and adhesive cues. Biomaterials (2013) 1.00
Manipulation of cell-cell adhesion using bowtie-shaped microwells. Methods Mol Biol (2007) 1.00
Decoupling diffusional from dimensional control of signaling in 3D culture reveals a role for myosin in tubulogenesis. J Cell Sci (2010) 1.00
Force-induced fibronectin assembly and matrix remodeling in a 3D microtissue model of tissue morphogenesis. Integr Biol (Camb) (2012) 0.99
Cell biology. Deconstructing dimensionality. Science (2013) 0.98
Contact inhibition of locomotion probabilities drive solitary versus collective cell migration. J R Soc Interface (2013) 0.98
Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway. J Cell Sci (2013) 0.97
Intraoperative fluorescence-guided resection of high-grade malignant gliomas using 5-aminolevulinic acid-induced porphyrins: a systematic review and meta-analysis of prospective studies. PLoS One (2013) 0.97
MicroRNA-153 is tumor suppressive in glioblastoma stem cells. Mol Biol Rep (2013) 0.96
Necking and failure of constrained 3D microtissues induced by cellular tension. Proc Natl Acad Sci U S A (2013) 0.96
Measuring traction forces of motile dendritic cells on micropost arrays. Biophys J (2011) 0.94
How cells sense extracellular matrix stiffness: a material's perspective. Curr Opin Biotechnol (2013) 0.93
Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients. Lab Chip (2013) 0.93
Adhesion regulates MAP kinase/ternary complex factor exchange to control a proliferative transcriptional switch. Curr Biol (2012) 0.93
Engineering amount of cell-cell contact demonstrates biphasic proliferative regulation through RhoA and the actin cytoskeleton. Exp Cell Res (2008) 0.93
Finite-element analysis of the adhesion-cytoskeleton-nucleus mechanotransduction pathway during endothelial cell rounding: axisymmetric model. J Biomech Eng (2005) 0.92
Micropatterned multicolor dynamically adhesive substrates to control cell adhesion and multicellular organization. Langmuir (2014) 0.92
Activation of beta 1 but not beta 3 integrin increases cell traction forces. FEBS Lett (2013) 0.92
MiR-106a is an independent prognostic marker in patients with glioblastoma. Neuro Oncol (2013) 0.92
Micropatterned dynamically adhesive substrates for cell migration. Langmuir (2010) 0.92
Combined passive and active microrheology study of protein-layer formation at an air-water interface. Langmuir (2010) 0.91