Published in J Gene Med on July 01, 2008
Co-immunization with DNA and protein mixture: a safe and efficacious immunotherapeutic strategy for Alzheimer's disease in PDAPP mice. Sci Rep (2015) 0.84
DNA and protein co-administration induces tolerogenic dendritic cells through DC-SIGN mediated negative signals. Hum Vaccin Immunother (2013) 0.78
Fel d 1-airway inflammation prevention and treatment by co-immunization vaccine via induction of CD4+CD25-Foxp3+ Treg cells. Hum Vaccin Immunother (2013) 0.77
Molecular adjuvant interleukin-33 enhances the antifertility effect of Lagurus lagurus zona pellucida 3 DNA vaccine administered by the mucosal route. Braz J Med Biol Res (2013) 0.75
Diabetes tolerogenic vaccines targeting antigen-specific inflammation. Hum Vaccin Immunother (2015) 0.75
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell (2011) 11.44
MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature (2003) 6.81
Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell (2012) 5.62
Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark. PLoS One (2007) 5.60
Effect of iodine intake on thyroid diseases in China. N Engl J Med (2006) 5.46
A GAL4-driver line resource for Drosophila neurobiology. Cell Rep (2012) 4.67
The shared antibiotic resistome of soil bacteria and human pathogens. Science (2012) 3.98
Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation. Nature (2008) 3.67
Evidence that microRNAs are associated with translating messenger RNAs in human cells. Nat Struct Mol Biol (2006) 3.36
MicroRNA-mediated control of oligodendrocyte differentiation. Neuron (2010) 3.24
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc Natl Acad Sci U S A (2003) 3.21
Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol (2006) 3.19
The deepest divergences in land plants inferred from phylogenomic evidence. Proc Natl Acad Sci U S A (2006) 3.10
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. Nat Chem Biol (2009) 3.03
WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity. Nature (2008) 2.86
Whole proteome prokaryote phylogeny without sequence alignment: a K-string composition approach. J Mol Evol (2004) 2.78
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proc Natl Acad Sci U S A (2006) 2.63
Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell (2008) 2.60
CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Res (2012) 2.50
Clinical progress and risk factors for death in severe fever with thrombocytopenia syndrome patients. J Infect Dis (2012) 2.49
Genome-scale functional profiling of the mammalian AP-1 signaling pathway. Proc Natl Acad Sci U S A (2003) 2.45
Tracing the origin and history of the HIV-2 epidemic. Proc Natl Acad Sci U S A (2003) 2.31
MicroRNAs inhibit the translation of target mRNAs on the endoplasmic reticulum in Arabidopsis. Cell (2013) 2.28
Structure and ubiquitin binding of the ubiquitin-interacting motif. J Biol Chem (2003) 2.19
External validation and prediction employing the predictive squared correlation coefficient test set activity mean vs training set activity mean. J Chem Inf Model (2008) 2.18
CpG DNA as a vaccine adjuvant. Expert Rev Vaccines (2011) 2.17
Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability. J Biol Chem (2003) 2.03
Chloride extrusion enhancers as novel therapeutics for neurological diseases. Nat Med (2013) 2.00
Mechanical assessment of two different methods of tripling hamstring tendons when using suspensory fixation. Knee Surg Sports Traumatol Arthrosc (2011) 1.99
The Plk1-dependent phosphoproteome of the early mitotic spindle. Mol Cell Proteomics (2010) 1.91
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis. Proc Natl Acad Sci U S A (2009) 1.91
Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay. J Biol Chem (2009) 1.91
An essential role for stromal interaction molecule 1 in neointima formation following arterial injury. Cardiovasc Res (2008) 1.87
Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway. J Immunol (2012) 1.86
Derivation of human embryonic stem cell lines from parthenogenetic blastocysts. Cell Res (2007) 1.83
China's primary health-care reform. Lancet (2011) 1.81
miR-146a controls the resolution of T cell responses in mice. J Exp Med (2012) 1.81
Bandgap engineering of strained monolayer and bilayer MoS2. Nano Lett (2013) 1.80
Mitogen-activated protein kinases mediate upregulation of hypothalamic angiotensin II type 1 receptors in heart failure rats. Hypertension (2008) 1.78
Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. EMBO J (2009) 1.76
Divergent global precipitation changes induced by natural versus anthropogenic forcing. Nature (2013) 1.75
Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease. J Biol Chem (2011) 1.75
RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects. Breast Cancer Res Treat (2010) 1.74
Hematocrit is associated with fibrosis in patients with nonalcoholic steatohepatitis. Eur J Gastroenterol Hepatol (2014) 1.71
Polymorphisms of tumor necrosis factor-alpha and breast cancer risk: a meta-analysis. Breast Cancer Res Treat (2010) 1.70
Oseltamivir resistance in adult oncology and hematology patients infected with pandemic (H1N1) 2009 virus, Australia. Emerg Infect Dis (2010) 1.70
Slc39a14 gene encodes ZIP14, a metal/bicarbonate symporter: similarities to the ZIP8 transporter. Mol Pharmacol (2008) 1.69
Developing a performance measurement framework and indicators for community health service facilities in urban China. BMC Fam Pract (2010) 1.68
Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis. Proc Natl Acad Sci U S A (2005) 1.67
Influenza H7N9 and H9N2 viruses: coexistence in poultry linked to human H7N9 infection and genome characteristics. J Virol (2014) 1.67
Mach-Zehnder interferometry in a strongly driven superconducting qubit. Science (2005) 1.65
A role for conditioned ventral tegmental glutamate release in cocaine seeking. J Neurosci (2007) 1.65
Hsa-mir-27a genetic variant contributes to gastric cancer susceptibility through affecting miR-27a and target gene expression. Cancer Sci (2010) 1.63
Emission factors of particulate matter and elemental carbon for crop residues and coals burned in typical household stoves in China. Environ Sci Technol (2010) 1.61
Induction of regulatory T cells by physiological level estrogen. J Cell Physiol (2008) 1.59
Liver-directed neonatal gene therapy prevents cardiac, bone, ear, and eye disease in mucopolysaccharidosis I mice. Mol Ther (2005) 1.58
Taxonomy of breast cancer based on normal cell phenotype predicts outcome. J Clin Invest (2014) 1.58
Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation. J Biol Chem (2009) 1.56
Null genotypes of GSTM1 and GSTT1 contribute to increased risk of diabetes mellitus: a meta-analysis. Gene (2013) 1.55
Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning. Proc Natl Acad Sci U S A (2007) 1.54
mGRASP enables mapping mammalian synaptic connectivity with light microscopy. Nat Methods (2011) 1.53
DJ-1 may contribute to metastasis of non-small cell lung cancer. Mol Biol Rep (2011) 1.52
The genome of Mesobuthus martensii reveals a unique adaptation model of arthropods. Nat Commun (2013) 1.50
A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila. Mol Cell (2013) 1.49
NHERF-1 and the cytoskeleton regulate the traffic and membrane dynamics of G protein-coupled receptors. J Biol Chem (2007) 1.48
Overprescribing in China, driven by financial incentives, results in very high use of antibiotics, injections, and corticosteroids. Health Aff (Millwood) (2012) 1.48
Cocaine serves as a peripheral interoceptive conditioned stimulus for central glutamate and dopamine release. PLoS One (2008) 1.47
Aldosterone acts centrally to increase brain renin-angiotensin system activity and oxidative stress in normal rats. Am J Physiol Heart Circ Physiol (2007) 1.46
Discovery of ZIP transporters that participate in cadmium damage to testis and kidney. Toxicol Appl Pharmacol (2009) 1.46
Improved neovascularization and wound repair by targeting human basic fibroblast growth factor (bFGF) to fibrin. J Mol Med (Berl) (2008) 1.46
Lack of an association between AURKA T91A polymorphisms and breast cancer: a meta-analysis involving 32,141 subjects. Breast Cancer Res Treat (2010) 1.46
Dexamethasone promotes tolerance in vivo by enriching CD11clo CD40lo tolerogenic macrophages. Eur J Immunol (2012) 1.45
Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection. Blood (2003) 1.44
Combined hepatocellular carcinoma and cholangiocarcinoma: a case report and review of the literature. Hepatobiliary Pancreat Dis Int (2007) 1.42
Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS. Retrovirology (2007) 1.41
NANOGP8 is a retrogene expressed in cancers. FEBS J (2006) 1.40
ac response of a carbon chain under a finite frequency bias. J Chem Phys (2007) 1.40
The 4-1BB costimulation augments the proliferation of CD4+CD25+ regulatory T cells. J Immunol (2004) 1.40
Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure. Circ Res (2006) 1.40
De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer. J Transl Med (2012) 1.40
MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells. Carcinogenesis (2011) 1.39
Antibacterial therapy improves the effectiveness of prostate cancer detection using prostate-specific antigen in patients with asymptomatic prostatitis. Int Urol Nephrol (2009) 1.39
Cigarette smoking and the risk of endometrial cancer: a meta-analysis. Am J Med (2008) 1.38
Black carbon emissions in China from 1949 to 2050. Environ Sci Technol (2012) 1.38
Melanoma-associated antigen genes - an update. Cancer Lett (2010) 1.36
The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling. J Pathol (2011) 1.36
Differentiation of bone marrow-derived mesenchymal stem cells from diabetic patients into insulin-producing cells in vitro. Chin Med J (Engl) (2007) 1.35
Free volume in imidazolium triflimide ([C3MIM][NTf2]) ionic liquid from positron lifetime: amorphous, crystalline, and liquid states. J Chem Phys (2010) 1.34
Analysis of differential BRAF(V600E) mutational status in high aggressive papillary thyroid microcarcinoma. Ann Surg Oncol (2008) 1.34
Metabolomics coupled with proteomics advancing drug discovery toward more agile development of targeted combination therapies. Mol Cell Proteomics (2013) 1.34
Alternative translation of OCT4 by an internal ribosome entry site and its novel function in stress response. Stem Cells (2009) 1.33
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. J Exp Med (2010) 1.33
Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway. Am J Physiol Heart Circ Physiol (2009) 1.32
Hierarchical leak detection and localization method in natural gas pipeline monitoring sensor networks. Sensors (Basel) (2011) 1.32
Emissions of PAHs from indoor crop residue burning in a typical rural stove: emission factors, size distributions, and gas-particle partitioning. Environ Sci Technol (2011) 1.32
Clinical features of solitary necrotic nodule of the liver. Hepatobiliary Pancreat Dis Int (2008) 1.32
Retromer is required for apoptotic cell clearance by phagocytic receptor recycling. Science (2010) 1.30