MicroRNA-mediated control of oligodendrocyte differentiation.

PubWeight™: 3.24‹?› | Rank: Top 1%

🔗 View Article (PMC 2855245)

Published in Neuron on March 11, 2010

Authors

Xianghui Zhao1, Xuelian He, Xiaolei Han, Yang Yu, Feng Ye, Ying Chen, ThaoNguyen Hoang, Xiaomei Xu, Qing-Sheng Mi, Mei Xin, Fan Wang, Bruce Appel, Q Richard Lu

Author Affiliations

1: Department of Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Articles citing this

(truncated to the top 100)

Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. Nat Rev Neurosci (2012) 2.52

Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter. Acta Neuropathol (2010) 1.71

Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell (2013) 1.66

Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration. J Neurosci (2011) 1.52

MicroRNAs: regulators of neuronal fate. Curr Opin Cell Biol (2013) 1.43

Regulation of microRNA function in somatic stem cell proliferation and differentiation. Nat Rev Mol Cell Biol (2014) 1.38

Functions of noncoding RNAs in neural development and neurological diseases. Mol Neurobiol (2011) 1.27

MicroRNA expression profiling of oligodendrocyte differentiation from human embryonic stem cells. PLoS One (2010) 1.24

IFNγ-stimulated dendritic cell exosomes as a potential therapeutic for remyelination. J Neuroimmunol (2013) 1.24

MicroRNA-deficient Schwann cells display congenital hypomyelination. J Neurosci (2010) 1.19

The emerging roles of microRNAs in CNS injuries. Nat Rev Neurol (2013) 1.18

Identification of a gene regulatory network necessary for the initiation of oligodendrocyte differentiation. PLoS One (2011) 1.11

Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors. Ann Neurol (2013) 1.11

MicroRNAs are essential for the developmental switch from neurogenesis to gliogenesis in the developing spinal cord. J Neurosci (2010) 1.10

MicroRNA in central nervous system trauma and degenerative disorders. Physiol Genomics (2011) 1.10

Retracted Comparative expression profile of miRNA and mRNA in primary peripheral blood mononuclear cells infected with human immunodeficiency virus (HIV-1). PLoS One (2011) 1.09

Oligodendrocyte fate after spinal cord injury. Neurotherapeutics (2011) 1.09

The emerging role of microRNAs in multiple sclerosis. Nat Rev Neurol (2010) 1.08

Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. PLoS One (2010) 1.07

Oligodendrogenesis after cerebral ischemia. Front Cell Neurosci (2013) 1.06

Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination. Glia (2013) 1.05

Extracellular vesicles round off communication in the nervous system. Nat Rev Neurosci (2016) 1.04

MicroRNAs tune cerebral cortical neurogenesis. Cell Death Differ (2012) 0.99

A potential regulatory role for intronic microRNA-338-3p for its host gene encoding apoptosis-associated tyrosine kinase. PLoS One (2012) 0.99

MiR-7 promotes epithelial cell transformation by targeting the tumor suppressor KLF4. PLoS One (2014) 0.98

MicroRNA dysregulation in the spinal cord following traumatic injury. PLoS One (2012) 0.98

Developmental regulation of microRNA expression in Schwann cells. Mol Cell Biol (2011) 0.98

MicroRNA-145 regulates human corneal epithelial differentiation. PLoS One (2011) 0.98

miR-219-5p inhibits receptor tyrosine kinase pathway by targeting EGFR in glioblastoma. PLoS One (2013) 0.97

MicroRNAs in neural cell differentiation. Brain Res (2010) 0.97

Transcriptome analysis of microRNAs in developing cerebral cortex of rat. BMC Genomics (2012) 0.96

Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128. Mol Cancer (2014) 0.96

Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatment. Lancet Neurol (2013) 0.96

Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes. Development (2013) 0.95

Spatial and temporal gene expression differences in core and periinfarct areas in experimental stroke: a microarray analysis. PLoS One (2012) 0.95

Let-7 and miR-125 cooperate to prime progenitors for astrogliogenesis. EMBO J (2015) 0.95

Involvement of microRNAs in regulation of osteoblastic differentiation in mouse induced pluripotent stem cells. PLoS One (2012) 0.95

MicroRNAs and Multiple Sclerosis. Autoimmune Dis (2010) 0.94

Unwrapping myelination by microRNAs. Neuroscientist (2011) 0.94

Mechanisms of oligodendrocyte regeneration from ventricular-subventricular zone-derived progenitor cells in white matter diseases. Front Cell Neurosci (2013) 0.94

Regulation of miRNA 219 and miRNA Clusters 338 and 17-92 in Oligodendrocytes. Front Genet (2012) 0.94

Sox6, jack of all trades: a versatile regulatory protein in vertebrate development. Dev Dyn (2011) 0.94

Oligodendrocytes and the "micro brake" of progenitor cell proliferation. Neuron (2010) 0.94

The QKI-5 and QKI-6 RNA binding proteins regulate the expression of microRNA 7 in glial cells. Mol Cell Biol (2013) 0.93

Isolation of cortical mouse oligodendrocyte precursor cells. J Neurosci Methods (2012) 0.93

Mediators of oligodendrocyte differentiation during remyelination. FEBS Lett (2011) 0.93

Circulating microRNAs are not eliminated by hemodialysis. PLoS One (2012) 0.93

MicroRNA dysregulation in multiple sclerosis. Front Genet (2013) 0.92

MicroRNA dysregulation in spinal cord injury: causes, consequences and therapeutics. Front Cell Neurosci (2014) 0.91

MicroRNAs and glial cell development. Neuroscientist (2011) 0.90

miR-219 regulates neural precursor differentiation by direct inhibition of apical par polarity proteins. Dev Cell (2013) 0.90

MicroRNA-23a promotes myelination in the central nervous system. Proc Natl Acad Sci U S A (2013) 0.90

MicroRNAs in oligodendrocyte and Schwann cell differentiation. Dev Neurosci (2011) 0.90

Glial cell development and function in zebrafish. Cold Spring Harb Perspect Biol (2014) 0.90

Polydendrocytes in development and myelin repair. Neurosci Bull (2013) 0.90

Time-dependent expression profiles of microRNAs and mRNAs in rat milk whey. PLoS One (2014) 0.89

Fine-Tuning Oligodendrocyte Development by microRNAs. Front Neurosci (2012) 0.89

miR-32 and its target SLC45A3 regulate the lipid metabolism of oligodendrocytes and myelin. Neuroscience (2012) 0.89

Coordinated control of oligodendrocyte development by extrinsic and intrinsic signaling cues. Neurosci Bull (2013) 0.88

miR-200 and miR-96 families repress neural induction from human embryonic stem cells. Development (2013) 0.88

MicroRNA profiling in human neutrophils during bone marrow granulopoiesis and in vivo exudation. PLoS One (2013) 0.88

The myelin brake: when enough is enough. Sci Signal (2010) 0.88

Advances with microRNAs in Parkinson's disease research. Drug Des Devel Ther (2013) 0.87

Approaches to manipulating microRNAs in neurogenesis. Front Neurosci (2013) 0.87

Oligodendrogenesis in the normal and pathological central nervous system. Front Neurosci (2014) 0.87

Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation. Front Neurosci (2012) 0.86

Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells. PLoS One (2010) 0.86

High-throughput experimental studies to identify miRNA targets directly, with special focus on the mammalian brain. Brain Res (2010) 0.86

Microprocessor Complex Subunit DiGeorge Syndrome Critical Region Gene 8 (Dgcr8) Is Required for Schwann Cell Myelination and Myelin Maintenance. J Biol Chem (2015) 0.85

Myelin basic protein synthesis is regulated by small non-coding RNA 715. EMBO Rep (2012) 0.85

Tuning the cell fate of neurons and glia by microRNAs. Curr Opin Neurobiol (2013) 0.84

The RE1 binding protein REST regulates oligodendrocyte differentiation. J Neurosci (2011) 0.84

New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte development. BMC Neurosci (2014) 0.84

Diversity Matters: A Revised Guide to Myelination. Trends Cell Biol (2015) 0.83

The transcriptome and miRNome profiling of glioblastoma tissues and peritumoral regions highlights molecular pathways shared by tumors and surrounding areas and reveals differences between short-term and long-term survivors. Oncotarget (2015) 0.83

miR-338-3p is over-expressed in blood, CFS, serum and spinal cord from sporadic amyotrophic lateral sclerosis patients. Neurogenetics (2014) 0.83

Promoting brain remodeling to aid in stroke recovery. Trends Mol Med (2015) 0.82

Regulation of Myelination in the Central Nervous System by Nuclear Lamin B1 and Non-coding RNAs. Transl Neurodegener (2014) 0.82

Specification and maintenance of oligodendrocyte precursor cells from neural progenitor cells: involvement of microRNA-7a. Mol Biol Cell (2012) 0.82

Oligodendrocyte progenitor programming and reprogramming: Toward myelin regeneration. Brain Res (2015) 0.82

Tcf7l2 is tightly controlled during myelin formation. Cell Mol Neurobiol (2011) 0.82

How to make an oligodendrocyte. Development (2015) 0.81

Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination. J Neurosci (2016) 0.81

Hypomyelination phenotype caused by impaired differentiation of oligodendrocytes in Emx1-cre mediated Cdk5 conditional knockout mice. Neurochem Res (2011) 0.81

The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. Nat Commun (2016) 0.80

MiR-223 regulates the differentiation of immature neurons. Mol Cell Ther (2014) 0.80

Adult-onset autosomal dominant leukodystrophy: linking nuclear envelope to myelin. J Neurosci (2011) 0.80

Interplay between transcriptional control and chromatin regulation in the oligodendrocyte lineage. Glia (2015) 0.80

MicroRNA and transcriptional crosstalk in myelinating glia. Neurochem Int (2014) 0.80

Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells. Skelet Muscle (2013) 0.80

A Genetic Variant in miRNA-219-1 Is Associated with Risk of Esophageal Squamous Cell Carcinoma in Chinese Kazakhs. Dis Markers (2015) 0.79

Subcortical ischemic vascular disease: Roles of oligodendrocyte function in experimental models of subcortical white-matter injury. J Cereb Blood Flow Metab (2016) 0.79

What are exosomes and how can they be used in multiple sclerosis therapy? Expert Rev Neurother (2014) 0.79

Epigenetics in NG2 glia cells. Brain Res (2015) 0.79

MicroRNA expression in mouse oligodendrocytes and regulation of proteolipid protein gene expression. J Neurosci Res (2012) 0.79

Heterogeneity of oligodendrocyte progenitor cells in adult human brain. Ann Clin Transl Neurol (2014) 0.79

MicroRNA delivery for regenerative medicine. Adv Drug Deliv Rev (2015) 0.79

Associations between DNA methylation and schizophrenia-related intermediate phenotypes - a gene set enrichment analysis. Prog Neuropsychopharmacol Biol Psychiatry (2015) 0.78

Emerging molecular targets for brain repair after stroke. Stroke Res Treat (2013) 0.78

Function of neural stem cells in ischemic brain repair processes. J Cereb Blood Flow Metab (2016) 0.78

Articles cited by this

MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59

MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17

Combinatorial microRNA target predictions. Nat Genet (2005) 50.48

MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell (2007) 38.42

MicroRNA expression in zebrafish embryonic development. Science (2005) 15.52

Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol (2008) 12.35

Axonal transection in the lesions of multiple sclerosis. N Engl J Med (1998) 12.21

Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev (2006) 11.04

The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci U S A (2005) 8.33

Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc Natl Acad Sci U S A (2003) 7.95

Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science (1995) 6.25

Biological principles of microRNA-mediated regulation: shared themes amid diversity. Nat Rev Genet (2008) 5.83

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell (2002) 5.64

Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Cell (1996) 5.27

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat Neurosci (2009) 5.27

The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev (2007) 5.16

microRNA modulation of circadian-clock period and entrainment. Neuron (2007) 4.49

A mitogen gradient of dorsal midline Wnts organizes growth in the CNS. Development (2002) 4.13

Notch receptor activation inhibits oligodendrocyte differentiation. Neuron (1998) 3.30

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci (2009) 3.18

Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat Med (2002) 3.04

Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes. J Neurosci (2008) 2.95

Common logic of transcription factor and microRNA action. Trends Biochem Sci (2004) 2.95

Regulation of oligodendrocyte development in the vertebrate CNS. Prog Neurobiol (2002) 2.81

Glial specification in the vertebrate neural tube. Nat Rev Neurosci (2004) 2.75

MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary. Nat Neurosci (2008) 2.65

Isolation and culture of rat and mouse oligodendrocyte precursor cells. Nat Protoc (2007) 2.46

Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice. J Neurosci (2005) 2.27

Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell (2009) 2.18

Neural cell fate analysis in zebrafish using olig2 BAC transgenics. Methods Cell Sci (2003) 2.14

IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes. J Cell Biol (2004) 2.02

MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proc Natl Acad Sci U S A (2009) 2.00

Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system. Dev Dyn (2009) 1.83

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell (2006) 1.79

Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann Neurol (2009) 1.62

Fine-tuning neural gene expression with microRNAs. Curr Opin Neurobiol (2009) 1.60

Otx2 regulates subtype specification and neurogenesis in the midbrain. J Neurosci (2005) 1.59

A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players. EMBO J (2006) 1.49

A matter of identity: transcriptional control in oligodendrocytes. J Mol Neurosci (2007) 1.47

Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation. Development (2000) 1.39

An intronic microRNA silences genes that are functionally antagonistic to its host gene. Nucleic Acids Res (2008) 1.27

Leukodystrophies: recent developments in genetics, molecular biology, pathogenesis and treatment. Curr Opin Neurol (2001) 1.15

The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol (2009) 1.13

Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging. Glia (2009) 1.09

MicroRNAs in common diseases and potential therapeutic applications. Clin Exp Pharmacol Physiol (2009) 0.98

A novel kinase, AATYK induces and promotes neuronal differentiation in a human neuroblastoma (SH-SY5Y) cell line. Brain Res Mol Brain Res (2000) 0.98

Post-translational modifications of nucleosomal histones in oligodendrocyte lineage cells in development and disease. J Mol Neurosci (2008) 0.96

Articles by these authors

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell (2009) 6.44

Effect of iodine intake on thyroid diseases in China. N Engl J Med (2006) 5.46

A GAL4-driver line resource for Drosophila neurobiology. Cell Rep (2012) 4.67

RPE65 is the isomerohydrolase in the retinoid visual cycle. Proc Natl Acad Sci U S A (2005) 4.61

Plasma soluble urokinase receptor levels are increased but do not distinguish primary from secondary focal segmental glomerulosclerosis. Kidney Int (2013) 3.97

Evidence that microRNAs are associated with translating messenger RNAs in human cells. Nat Struct Mol Biol (2006) 3.36

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc Natl Acad Sci U S A (2003) 3.21

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci (2009) 3.18

Reelin promoter hypermethylation in schizophrenia. Proc Natl Acad Sci U S A (2005) 3.12

High expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation. Med Oncol (2010) 3.06

MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res (2011) 3.03

Reelin, lipoprotein receptors and synaptic plasticity. Nat Rev Neurosci (2006) 2.95

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood (2009) 2.91

Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med (2007) 2.85

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. EMBO J (2009) 2.76

SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site. Dev Cell (2004) 2.74

A local mechanism mediates NAD-dependent protection of axon degeneration. J Cell Biol (2005) 2.64

The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proc Natl Acad Sci U S A (2006) 2.63

Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell (2003) 2.54

Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway. Proc Natl Acad Sci U S A (2010) 2.53

CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Res (2012) 2.50

Isolation and culture of rat and mouse oligodendrocyte precursor cells. Nat Protoc (2007) 2.46

Genome-scale functional profiling of the mammalian AP-1 signaling pathway. Proc Natl Acad Sci U S A (2003) 2.45

In vivo time-lapse imaging shows dynamic oligodendrocyte progenitor behavior during zebrafish development. Nat Neurosci (2006) 2.42

Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis. Dev Biol (2005) 2.38

Organic cation transporters are determinants of oxaliplatin cytotoxicity. Cancer Res (2006) 2.37

Regulation of integrin activation. Annu Rev Cell Dev Biol (2011) 2.32

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. J Biol Chem (2007) 2.31

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci (2012) 2.28

Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice. J Neurosci (2005) 2.27

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26

Toxicity of atmospheric aerosols on marine phytoplankton. Proc Natl Acad Sci U S A (2009) 2.25

Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease. Blood (2008) 2.24

Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma. Am J Gastroenterol (2010) 2.20

Meta-analysis of B vitamin supplementation on plasma homocysteine, cardiovascular and all-cause mortality. Clin Nutr (2012) 2.17

A dynamic gene expression atlas covering the entire life cycle of rice. Plant J (2009) 2.15

Neural cell fate analysis in zebrafish using olig2 BAC transgenics. Methods Cell Sci (2003) 2.14

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology (2007) 2.11

Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development. Proc Natl Acad Sci U S A (2008) 2.08

Insulin resistance in children with primary nephrotic syndrome and normal renal function. Pediatr Nephrol (2012) 2.03

Dietary and lifestyle changes associated with high prevalence of hyperuricemia and gout in the Shandong coastal cities of Eastern China. J Rheumatol (2008) 2.00

Spatial segregation of gamma-secretase and substrates in distinct membrane domains. J Biol Chem (2005) 1.98

Sample size calculations for evaluating a diagnostic test when the gold standard is missing at random. Stat Med (2010) 1.96

Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons. Proc Natl Acad Sci U S A (2007) 1.95

DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. Mol Pharmacol (2006) 1.95

Primate-specific microRNA-637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting signal transducer and activator of transcription 3 signaling. Hepatology (2011) 1.93

Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth. Proc Natl Acad Sci U S A (2005) 1.93

Initial Evaluation of [(18)F]DCFPyL for Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer. Mol Imaging Biol (2015) 1.90

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet (2010) 1.90

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response. J Biol Chem (2002) 1.87

An essential role for stromal interaction molecule 1 in neointima formation following arterial injury. Cardiovasc Res (2008) 1.87

A regulatory toolbox of MiniPromoters to drive selective expression in the brain. Proc Natl Acad Sci U S A (2010) 1.85

Derivation of human embryonic stem cell lines from parthenogenetic blastocysts. Cell Res (2007) 1.83

Targeted deletion of Dicer from proximal tubules protects against renal ischemia-reperfusion injury. J Am Soc Nephrol (2010) 1.82

miR-146a controls the resolution of T cell responses in mice. J Exp Med (2012) 1.81

Aberrant regulation of planar cell polarity in polycystic kidney disease. J Am Soc Nephrol (2010) 1.81

olig2 is required for zebrafish primary motor neuron and oligodendrocyte development. Dev Biol (2002) 1.79

Regulation of cardiomyocyte signaling by RGS proteins: differential selectivity towards G proteins and susceptibility to regulation. J Mol Cell Cardiol (2006) 1.78

Mitogen-activated protein kinases mediate upregulation of hypothalamic angiotensin II type 1 receptors in heart failure rats. Hypertension (2008) 1.78

Undisclosed antiretroviral drug use in a multinational clinical trial (HIV Prevention Trials Network 052). J Infect Dis (2013) 1.77

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum Mol Genet (2012) 1.77

Genetically altered mice to evaluate glutathione homeostasis in health and disease. Free Radic Biol Med (2004) 1.76

Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria. J Am Coll Cardiol (2011) 1.76

Tie2cre-induced inactivation of the miRNA-processing enzyme Dicer disrupts invariant NKT cell development. Proc Natl Acad Sci U S A (2009) 1.75

Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells. Stem Cells (2010) 1.75

RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects. Breast Cancer Res Treat (2010) 1.74

CNS-derived glia ensheath peripheral nerves and mediate motor root development. Nat Neurosci (2008) 1.73

Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons. Nat Commun (2012) 1.72

Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist. Sci Signal (2013) 1.71

Seasonal dynamics and age of stemwood nonstructural carbohydrates in temperate forest trees. New Phytol (2012) 1.70

Polymorphisms of tumor necrosis factor-alpha and breast cancer risk: a meta-analysis. Breast Cancer Res Treat (2010) 1.70

ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells (2012) 1.70

(68)Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin alphavbeta3 PET imaging. Eur J Nucl Med Mol Imaging (2009) 1.69

Müller cell-derived VEGF is a significant contributor to retinal neovascularization. J Pathol (2009) 1.69

HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nat Neurosci (2011) 1.67

Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene. J Neurosci (2007) 1.67

Influenza H7N9 and H9N2 viruses: coexistence in poultry linked to human H7N9 infection and genome characteristics. J Virol (2014) 1.67

Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell (2013) 1.66

Mach-Zehnder interferometry in a strongly driven superconducting qubit. Science (2005) 1.65

Small RNAs have a large impact: circulating microRNAs as biomarkers for human diseases. RNA Biol (2012) 1.64

Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. Nat Cell Biol (2013) 1.64

Are there differences between women's and men's antidepressant responses? Am J Psychiatry (2002) 1.64

Genetic composition of yield heterosis in an elite rice hybrid. Proc Natl Acad Sci U S A (2012) 1.63

Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacol Rev (2012) 1.62

Spatial and temporal regulation of ventral spinal cord precursor specification by Hedgehog signaling. Development (2004) 1.62

A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples. Circ Res (2012) 1.61

Hydrogen sulfide treatment promotes glucose uptake by increasing insulin receptor sensitivity and ameliorates kidney lesions in type 2 diabetes. Antioxid Redox Signal (2013) 1.60

The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Nat Neurosci (2009) 1.60

Basolateral targeting and microtubule-dependent transcytosis of the aquaporin-2 water channel. Am J Physiol Cell Physiol (2012) 1.60

A crucial role for Olig2 in white matter astrocyte development. Development (2007) 1.60

Progressive miRNA expression profiles in cervical carcinogenesis and identification of HPV-related target genes for miR-29. J Pathol (2011) 1.57

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination. Proc Natl Acad Sci U S A (2011) 1.57