Published in Org Lett on May 02, 2008
Novel and efficient one-step parallel synthesis of dibenzopyranones via Suzuki-Miyaura cross coupling. J Comb Chem (2010) 0.78
Highly enantioselective access to cannabinoid-type tricyles by organocatalytic Diels-Alder reactions. Beilstein J Org Chem (2012) 0.75
An endophytic fungus isolated from finger millet (Eleusine coracana) produces anti-fungal natural products. Front Microbiol (2015) 0.75
Light-activated kinases enable temporal dissection of signaling networks in living cells. J Am Chem Soc (2011) 2.22
Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry. J Am Chem Soc (2009) 2.06
Small-molecule inhibitors of microrna miR-21 function. Angew Chem Int Ed Engl (2008) 2.00
Genetically encoded photocontrol of protein localization in mammalian cells. J Am Chem Soc (2010) 1.94
A genetically encoded fluorescent amino acid. Proc Natl Acad Sci U S A (2006) 1.66
A genetically encoded photocaged amino acid. J Am Chem Soc (2004) 1.65
Photochemical control of biological processes. Org Biomol Chem (2006) 1.64
Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair. J Am Chem Soc (2010) 1.53
Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. J Am Chem Soc (2010) 1.53
Gene silencing in mammalian cells with light-activated antisense agents. Chembiochem (2008) 1.33
Recent advances in the photochemical control of protein function. Trends Biotechnol (2010) 1.32
Photochemical DNA activation. Org Lett (2007) 1.25
Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. J Am Chem Soc (2010) 1.23
Light-activated Cre recombinase as a tool for the spatial and temporal control of gene function in mammalian cells. ACS Chem Biol (2009) 1.23
Development of a robust and high throughput method for profiling N-linked glycans derived from plasma glycoproteins by NanoLC-FTICR mass spectrometry. J Proteome Res (2009) 1.19
Generating permissive site-specific unnatural aminoacyl-tRNA synthetases. Biochemistry (2010) 1.10
Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells. J Am Chem Soc (2010) 1.09
Light-triggered polymerase chain reaction. Chem Commun (Camb) (2007) 1.04
Photochemical activation of protein expression in bacterial cells. Angew Chem Int Ed Engl (2007) 1.04
Tricyclic alkaloid core structures assembled by a cyclotrimerization-coupled intramolecular nucleophilic substitution reaction. Org Lett (2010) 1.03
The human mitochondrial tRNAMet: structure/function relationship of a unique modification in the decoding of unconventional codons. J Mol Biol (2010) 1.03
Photocontrol of tyrosine phosphorylation in mammalian cells via genetic encoding of photocaged tyrosine. J Am Chem Soc (2012) 1.02
Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human mitochondrial tRNAMet. Nucleic Acids Res (2008) 1.02
High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function. J Biomol Screen (2012) 0.98
Light-activated deoxyguanosine: photochemical regulation of peroxidase activity. Mol Biosyst (2008) 0.98
Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells. J Am Chem Soc (2013) 0.98
Photochemical hammerhead ribozyme activation. Bioorg Med Chem Lett (2006) 0.97
Microwave activation of enzymatic catalysis. J Am Chem Soc (2008) 0.96
Optical control of protein function through unnatural amino acid mutagenesis and other optogenetic approaches. ACS Chem Biol (2014) 0.95
DNA computation in mammalian cells: microRNA logic operations. J Am Chem Soc (2013) 0.95
A light-activated DNA polymerase. Angew Chem Int Ed Engl (2009) 0.95
Photocaged t7 RNA polymerase for the light activation of transcription and gene function in pro- and eukaryotic cells. Chembiochem (2010) 0.94
Light-controlled synthetic gene circuits. Curr Opin Chem Biol (2012) 0.94
DNA computation: a photochemically controlled AND gate. J Am Chem Soc (2012) 0.93
Photochemical control of DNA decoy function enables precise regulation of nuclear factor κB activity. J Am Chem Soc (2011) 0.93
Light-activation of gene function in mammalian cells via ribozymes. Chem Commun (Camb) (2008) 0.92
Light-regulated RNA-small molecule interactions. Chembiochem (2008) 0.92
Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation. J Am Chem Soc (2014) 0.91
Site-specific incorporation of fluorotyrosines into proteins in Escherichia coli by photochemical disguise. Biochemistry (2010) 0.89
A general approach to chemo- and regioselective cyclotrimerization reactions. Angew Chem Int Ed Engl (2007) 0.89
Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes. Chem Commun (Camb) (2014) 0.88
Sequential gene silencing using wavelength-selective caged morpholino oligonucleotides. Angew Chem Int Ed Engl (2014) 0.88
Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells. ACS Chem Biol (2012) 0.88
Optochemical control of deoxyoligonucleotide function via a nucleobase-caging approach. Acc Chem Res (2013) 0.87
Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities. Bioconjug Chem (2014) 0.86
Spatiotemporal control of microRNA function using light-activated antagomirs. Mol Biosyst (2012) 0.85
A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos. Development (2012) 0.85
Light-activated gene editing with a photocaged zinc-finger nuclease. Angew Chem Int Ed Engl (2011) 0.83
Genetic encoding of caged cysteine and caged homocysteine in bacterial and mammalian cells. Chembiochem (2014) 0.83
Optochemical control of RNA interference in mammalian cells. Nucleic Acids Res (2013) 0.82
Photochemical regulation of restriction endonuclease activity. Chembiochem (2009) 0.82
The effect of microwave irradiation on DNA hybridization. Org Biomol Chem (2009) 0.82
Interfacing synthetic DNA logic operations with protein outputs. Angew Chem Int Ed Engl (2014) 0.82
Heterotaxin: a TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos. Chem Biol (2011) 0.81
Microwave-mediated nickel-catalyzed cyclotrimerization reactions: total synthesis of illudinine. J Org Chem (2007) 0.81
Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry. J Comb Chem (2007) 0.81
Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization. Nucleic Acids Res (2009) 0.80
Synthesis of the pyridine core of cyclothiazomycin. Org Lett (2011) 0.80
Cellular delivery and photochemical activation of antisense agents through a nucleobase caging strategy. ACS Chem Biol (2013) 0.80
Control of protein function through optochemical translocation. ACS Synth Biol (2014) 0.80
Solid-supported [2+2+2] cyclotrimerizations. Chemistry (2006) 0.79
Improved synthesis of the two-photon caging group 3-nitro-2-ethyldibenzofuran and its application to a caged thymidine phosphoramidite. Org Lett (2010) 0.79
Intracellular light-activation of riboswitch activity. Chembiochem (2014) 0.79
Microwave-assisted synthesis of unnatural amino acids. Bioorg Med Chem Lett (2008) 0.79
Light-cleavable rapamycin dimer as an optical trigger for protein dimerization. Chem Commun (Camb) (2015) 0.79
Reversible light switching of cell signalling by genetically encoded protein dimerization. Chembiochem (2010) 0.79
Pyridines via solid-supported [2 + 2 + 2] cyclotrimerization. Chem Commun (Camb) (2006) 0.78
Photochemical control of bacterial signal processing using a light-activated erythromycin. Mol Biosyst (2011) 0.78
Site-specific promoter caging enables optochemical gene activation in cells and animals. J Am Chem Soc (2014) 0.78
Hydrogen peroxide induced activation of gene expression in mammalian cells using boronate estrone derivatives. Angew Chem Int Ed Engl (2012) 0.78
Thiourea-based fluorescent chemosensors for aqueous metal ion detection and cellular imaging. J Org Chem (2014) 0.77
Phenanthridine synthesis via [2+2+2] cyclotrimerization reactions. Org Biomol Chem (2007) 0.77
Cellular microRNA sensors based on luciferase reporters. Methods Mol Biol (2014) 0.77
Photocleavable polyethylene glycol for the light-regulation of protein function. Bioconjug Chem (2010) 0.77
Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization. J Org Chem (2007) 0.76
Identification of inhibitors of microRNA function from small molecule screens. Methods Mol Biol (2014) 0.76
Stabilization and photochemical regulation of antisense agents through PEGylation. Bioconjug Chem (2011) 0.76
Control of oncogenic miRNA function by light-activated miRNA antagomirs. Methods Mol Biol (2014) 0.76
A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine. Chem Commun (Camb) (2008) 0.75
Optochemical activation of kinase function in live cells. Methods Mol Biol (2014) 0.75
Synthesis of anthracene and azaanthracene fluorophores via [2+2+2] cyclotrimerization reactions. Org Lett (2008) 0.75
Total synthesis of cryptoacetalide. J Org Chem (2010) 0.75
Engineering a bacterial tape recorder. Chembiochem (2015) 0.75
Modulating the pKa of a tyrosine in KlenTaq DNA polymerase that is crucial for abasic site bypass by in vivo incorporation of a non-canonical amino acid. Chembiochem (2014) 0.75