Published in Chembiochem on May 26, 2014
Photocaged DNAzymes as a general method for sensing metal ions in living cells. Angew Chem Int Ed Engl (2014) 0.87
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Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds. ACS Chem Biol (2009) 2.67
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Retracted Reprogramming bacteria to seek and destroy an herbicide. Nat Chem Biol (2010) 2.39
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Riboswitch control of gene expression in plants by splicing and alternative 3' end processing of mRNAs. Plant Cell (2007) 2.18
Light-controlled tools. Angew Chem Int Ed Engl (2012) 1.96
Thiamine biosynthesis in algae is regulated by riboswitches. Proc Natl Acad Sci U S A (2007) 1.57
A high-throughput screen for synthetic riboswitches reveals mechanistic insights into their function. Chem Biol (2007) 1.56
Reengineering orthogonally selective riboswitches. Proc Natl Acad Sci U S A (2010) 1.41
Principles and applications of the photochemical control of cellular processes. Chembiochem (2010) 1.33
Synthetic riboswitches that induce gene expression in diverse bacterial species. Appl Environ Microbiol (2010) 1.29
A flow cytometry-based screen for synthetic riboswitches. Nucleic Acids Res (2008) 1.28
Reengineering a natural riboswitch by dual genetic selection. J Am Chem Soc (2007) 1.15
Aptamers and riboswitches: perspectives in biotechnology. Appl Microbiol Biotechnol (2009) 1.09
Engineered riboswitches: Expanding researchers' toolbox with synthetic RNA regulators. FEBS Lett (2012) 1.08
Emerging applications of riboswitches in chemical biology. ACS Chem Biol (2010) 1.05
Modularity of select riboswitch expression platforms enables facile engineering of novel genetic regulatory devices. ACS Synth Biol (2013) 1.04
Inducible gene expression from the plastid genome by a synthetic riboswitch. Proc Natl Acad Sci U S A (2010) 1.04
Photochemical hammerhead ribozyme activation. Bioorg Med Chem Lett (2006) 0.97
Eukaryotic TPP riboswitch regulation of alternative splicing involving long-distance base pairing. Nucleic Acids Res (2013) 0.97
Light-controlled synthetic gene circuits. Curr Opin Chem Biol (2012) 0.94
Using a riboswitch sensor to examine coenzyme B(12) metabolism and transport in E. coli. Chem Biol (2010) 0.92
Light-activation of gene function in mammalian cells via ribozymes. Chem Commun (Camb) (2008) 0.92
Synthetic riboswitches for the conditional control of gene expression in Streptomyces coelicolor. Microbiology (2013) 0.92
Reversible photo-regulation of a hammerhead ribozyme using a diffusible effector. J Mol Biol (2007) 0.81
High-throughput screens to discover synthetic riboswitches. Methods Mol Biol (2009) 0.79
Caged glucosamine-6-phosphate for the light-control of riboswitch activity. Photochem Photobiol Sci (2011) 0.78
Light-activated kinases enable temporal dissection of signaling networks in living cells. J Am Chem Soc (2011) 2.22
Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry. J Am Chem Soc (2009) 2.06
Small-molecule inhibitors of microrna miR-21 function. Angew Chem Int Ed Engl (2008) 2.00
Genetically encoded photocontrol of protein localization in mammalian cells. J Am Chem Soc (2010) 1.94
Recombinant E. coli prototype strains for in vivo glycorandomization. ACS Chem Biol (2010) 1.82
A genetically encoded fluorescent amino acid. Proc Natl Acad Sci U S A (2006) 1.66
A genetically encoded photocaged amino acid. J Am Chem Soc (2004) 1.65
Photochemical control of biological processes. Org Biomol Chem (2006) 1.64
Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair. J Am Chem Soc (2010) 1.53
Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. J Am Chem Soc (2010) 1.53
Gene silencing in mammalian cells with light-activated antisense agents. Chembiochem (2008) 1.33
Recent advances in the photochemical control of protein function. Trends Biotechnol (2010) 1.32
Photochemical DNA activation. Org Lett (2007) 1.25
Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. J Am Chem Soc (2010) 1.23
Light-activated Cre recombinase as a tool for the spatial and temporal control of gene function in mammalian cells. ACS Chem Biol (2009) 1.23
Development of a robust and high throughput method for profiling N-linked glycans derived from plasma glycoproteins by NanoLC-FTICR mass spectrometry. J Proteome Res (2009) 1.19
Probing the aglycon promiscuity of an engineered glycosyltransferase. Angew Chem Int Ed Engl (2008) 1.12
Generating permissive site-specific unnatural aminoacyl-tRNA synthetases. Biochemistry (2010) 1.10
Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells. J Am Chem Soc (2010) 1.09
Light-triggered polymerase chain reaction. Chem Commun (Camb) (2007) 1.04
Photochemical activation of protein expression in bacterial cells. Angew Chem Int Ed Engl (2007) 1.04
The human mitochondrial tRNAMet: structure/function relationship of a unique modification in the decoding of unconventional codons. J Mol Biol (2010) 1.03
Mutant malonyl-CoA synthetases with altered specificity for polyketide synthase extender unit generation. Chembiochem (2011) 1.03
Tricyclic alkaloid core structures assembled by a cyclotrimerization-coupled intramolecular nucleophilic substitution reaction. Org Lett (2010) 1.03
Photocontrol of tyrosine phosphorylation in mammalian cells via genetic encoding of photocaged tyrosine. J Am Chem Soc (2012) 1.02
Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human mitochondrial tRNAMet. Nucleic Acids Res (2008) 1.02
Poly specific trans-acyltransferase machinery revealed via engineered acyl-CoA synthetases. ACS Chem Biol (2012) 1.02
High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function. J Biomol Screen (2012) 0.98
Light-activated deoxyguanosine: photochemical regulation of peroxidase activity. Mol Biosyst (2008) 0.98
Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells. J Am Chem Soc (2013) 0.98
Photochemical hammerhead ribozyme activation. Bioorg Med Chem Lett (2006) 0.97
Microwave activation of enzymatic catalysis. J Am Chem Soc (2008) 0.96
Optical control of protein function through unnatural amino acid mutagenesis and other optogenetic approaches. ACS Chem Biol (2014) 0.95
DNA computation in mammalian cells: microRNA logic operations. J Am Chem Soc (2013) 0.95
Promiscuity of a modular polyketide synthase towards natural and non-natural extender units. Org Biomol Chem (2013) 0.95
A light-activated DNA polymerase. Angew Chem Int Ed Engl (2009) 0.95
Photocaged t7 RNA polymerase for the light activation of transcription and gene function in pro- and eukaryotic cells. Chembiochem (2010) 0.94
Light-controlled synthetic gene circuits. Curr Opin Chem Biol (2012) 0.94
DNA computation: a photochemically controlled AND gate. J Am Chem Soc (2012) 0.93
Photochemical control of DNA decoy function enables precise regulation of nuclear factor κB activity. J Am Chem Soc (2011) 0.93
Pathologic features of ulcerative colitis in patients with primary sclerosing cholangitis: a case-control study. Am J Surg Pathol (2009) 0.92
Light-activation of gene function in mammalian cells via ribozymes. Chem Commun (Camb) (2008) 0.92
Light-regulated RNA-small molecule interactions. Chembiochem (2008) 0.92
Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation. J Am Chem Soc (2014) 0.91
Site-specific incorporation of fluorotyrosines into proteins in Escherichia coli by photochemical disguise. Biochemistry (2010) 0.89
A general approach to chemo- and regioselective cyclotrimerization reactions. Angew Chem Int Ed Engl (2007) 0.89
Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes. Chem Commun (Camb) (2014) 0.88
Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells. ACS Chem Biol (2012) 0.88
Sequential gene silencing using wavelength-selective caged morpholino oligonucleotides. Angew Chem Int Ed Engl (2014) 0.88
Optochemical control of deoxyoligonucleotide function via a nucleobase-caging approach. Acc Chem Res (2013) 0.87
Plasmablastic lymphoma of head and neck: report of two new cases and correlation with c-myc and IgVH gene mutation status. Head Neck Pathol (2007) 0.86
Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities. Bioconjug Chem (2014) 0.86
Spatiotemporal control of microRNA function using light-activated antagomirs. Mol Biosyst (2012) 0.85
A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos. Development (2012) 0.85
A cyclotrimerization route to cannabinoids. Org Lett (2008) 0.84
The prognostic value of creatine kinase elevations extends across the whole spectrum of acute coronary syndromes. J Am Coll Cardiol (2002) 0.84
Light-activated gene editing with a photocaged zinc-finger nuclease. Angew Chem Int Ed Engl (2011) 0.83
Genetic encoding of caged cysteine and caged homocysteine in bacterial and mammalian cells. Chembiochem (2014) 0.83
A preliminary report on the effects of paclitaxel-impregnated stents on sheep nasal mucosa. Am J Rhinol (2004) 0.83
Fungal nasal septal abscess in the immunocompromised patient. Otolaryngol Head Neck Surg (2007) 0.83
Optochemical control of RNA interference in mammalian cells. Nucleic Acids Res (2013) 0.82
Photochemical regulation of restriction endonuclease activity. Chembiochem (2009) 0.82
The effect of microwave irradiation on DNA hybridization. Org Biomol Chem (2009) 0.82
Interfacing synthetic DNA logic operations with protein outputs. Angew Chem Int Ed Engl (2014) 0.82
Microwave-mediated nickel-catalyzed cyclotrimerization reactions: total synthesis of illudinine. J Org Chem (2007) 0.81
Periportal lymphadenopathy in patients without identifiable pancreatobiliary or hepatic malignancy. Clin Gastroenterol Hepatol (2006) 0.81
Heterotaxin: a TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos. Chem Biol (2011) 0.81
Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry. J Comb Chem (2007) 0.81
Synthesis of the pyridine core of cyclothiazomycin. Org Lett (2011) 0.80
Cellular delivery and photochemical activation of antisense agents through a nucleobase caging strategy. ACS Chem Biol (2013) 0.80
Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization. Nucleic Acids Res (2009) 0.80
Control of protein function through optochemical translocation. ACS Synth Biol (2014) 0.80
Light-cleavable rapamycin dimer as an optical trigger for protein dimerization. Chem Commun (Camb) (2015) 0.79
Solid-supported [2+2+2] cyclotrimerizations. Chemistry (2006) 0.79
Microwave-assisted synthesis of unnatural amino acids. Bioorg Med Chem Lett (2008) 0.79
Reversible light switching of cell signalling by genetically encoded protein dimerization. Chembiochem (2010) 0.79
Improved synthesis of the two-photon caging group 3-nitro-2-ethyldibenzofuran and its application to a caged thymidine phosphoramidite. Org Lett (2010) 0.79
Photochemical control of bacterial signal processing using a light-activated erythromycin. Mol Biosyst (2011) 0.78
Pyridines via solid-supported [2 + 2 + 2] cyclotrimerization. Chem Commun (Camb) (2006) 0.78
Site-specific promoter caging enables optochemical gene activation in cells and animals. J Am Chem Soc (2014) 0.78
Hydrogen peroxide induced activation of gene expression in mammalian cells using boronate estrone derivatives. Angew Chem Int Ed Engl (2012) 0.78
Evaluating nonpolar surface area and liquid chromatography/mass spectrometry response: an application for site occupancy measurements for enzyme intermediates in polyketide biosynthesis. Rapid Commun Mass Spectrom (2014) 0.78
Phenanthridine synthesis via [2+2+2] cyclotrimerization reactions. Org Biomol Chem (2007) 0.77
Cellular microRNA sensors based on luciferase reporters. Methods Mol Biol (2014) 0.77
Photocleavable polyethylene glycol for the light-regulation of protein function. Bioconjug Chem (2010) 0.77
Thiourea-based fluorescent chemosensors for aqueous metal ion detection and cellular imaging. J Org Chem (2014) 0.77
A photocrosslinking assay for reporting protein interactions in polyketide and fatty acid synthases. Mol Biosyst (2011) 0.76
Identification of inhibitors of microRNA function from small molecule screens. Methods Mol Biol (2014) 0.76
Mapping a ketosynthase:acyl carrier protein binding interface via unnatural amino acid-mediated photo-cross-linking. Biochemistry (2014) 0.76
Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization. J Org Chem (2007) 0.76
Control of oncogenic miRNA function by light-activated miRNA antagomirs. Methods Mol Biol (2014) 0.76
Stabilization and photochemical regulation of antisense agents through PEGylation. Bioconjug Chem (2011) 0.76
A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine. Chem Commun (Camb) (2008) 0.75
Synthesis of anthracene and azaanthracene fluorophores via [2+2+2] cyclotrimerization reactions. Org Lett (2008) 0.75
Optochemical activation of kinase function in live cells. Methods Mol Biol (2014) 0.75
Total synthesis of cryptoacetalide. J Org Chem (2010) 0.75
Engineering a bacterial tape recorder. Chembiochem (2015) 0.75
A high-throughput screen for directed evolution of the natural product sulfotransferase LipB. J Biomol Screen (2011) 0.75
Clinical problem solving: pathology: pathology quiz case 1. Atypical mycobacterial infection. Arch Otolaryngol Head Neck Surg (2002) 0.75
A high-throughput screen for directed evolution of aminocoumarin amide synthetases. Anal Biochem (2011) 0.75