PubRank

Helga E de Vries

Author PubWeight™ 78.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science 2011 3.52
2 Macrophages and neurodegeneration. Brain Res Brain Res Rev 2005 1.64
3 Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling. FASEB J 2007 1.63
4 Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction. J Neurochem 2006 1.43
5 Radical changes in multiple sclerosis pathogenesis. Biochim Biophys Acta 2010 1.40
6 Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement. Brain 2008 1.38
7 Diapedesis of monocytes is associated with MMP-mediated occludin disappearance in brain endothelial cells. FASEB J 2006 1.34
8 Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration? Mitochondrion 2010 1.34
9 Flavonoids influence monocytic GTPase activity and are protective in experimental allergic encephalitis. J Exp Med 2004 1.34
10 The blood-brain barrier and its role in immune privilege in the central nervous system. J Neuropathol Exp Neurol 2003 1.32
11 Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity. J Immunol 2006 1.30
12 Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy. Antioxid Redox Signal 2011 1.29
13 Comparison of SPIO and USPIO for in vitro labeling of human monocytes: MR detection and cell function. Radiology 2007 1.28
14 Fingolimod attenuates ceramide-induced blood-brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes. Acta Neuropathol 2012 1.22
15 Interferon-beta prevents cytokine-induced neutrophil infiltration and attenuates blood-brain barrier disruption. J Cereb Blood Flow Metab 2003 1.21
16 The blood-brain barrier in cortical multiple sclerosis lesions. J Neuropathol Exp Neurol 2007 1.20
17 Retinoic acid induces blood-brain barrier development. J Neurosci 2013 1.17
18 RhoA activation promotes transendothelial migration of monocytes via ROCK. J Leukoc Biol 2003 1.16
19 Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation. Epilepsia 2012 1.15
20 Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis. Neurobiol Dis 2005 1.14
21 Matrix metalloproteinase-12 is expressed in phagocytotic macrophages in active multiple sclerosis lesions. J Neuroimmunol 2003 1.14
22 Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation. J Neuroinflammation 2012 1.09
23 MRI of monocyte infiltration in an animal model of neuroinflammation using SPIO-labeled monocytes or free USPIO. J Cereb Blood Flow Metab 2007 1.07
24 MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis. J Neurosci 2013 1.07
25 Ultrasound and microbubble-induced intra- and intercellular bioeffects in primary endothelial cells. Ultrasound Med Biol 2009 1.07
26 SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function. Am J Physiol Heart Circ Physiol 2007 1.05
27 Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology. Brain Res Rev 2007 1.04
28 Basement membrane proteins in multiple sclerosis-associated inflammatory cuffs: potential role in influx and transport of leukocytes. J Neuropathol Exp Neurol 2005 1.03
29 Extensive extracellular matrix depositions in active multiple sclerosis lesions. Neurobiol Dis 2006 1.02
30 Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions. Free Radic Biol Med 2010 1.00
31 Functions of lipid raft membrane microdomains at the blood-brain barrier. J Mol Med (Berl) 2009 0.99
32 Soluble helminth products suppress clinical signs in murine experimental autoimmune encephalomyelitis and differentially modulate human dendritic cell activation. Mol Immunol 2012 0.98
33 Leukemia inhibitory factor modulates production of inflammatory mediators and myelin phagocytosis by macrophages. J Neuroimmunol 2008 0.97
34 Macrophages migrate in an activation-dependent manner to chemokines involved in neuroinflammation. J Neuroinflammation 2014 0.97
35 Adenosine triphosphate-binding cassette transporters mediate chemokine (C-C motif) ligand 2 secretion from reactive astrocytes: relevance to multiple sclerosis pathogenesis. Brain 2010 0.96
36 Tumor infiltrating macrophages reduce development of peritoneal colorectal carcinoma metastases. Cancer Lett 2008 0.95
37 Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier. J Immunol 2008 0.95
38 Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma. FASEB J 2012 0.95
39 Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex. Acta Neuropathol 2012 0.95
40 Flavonoids inhibit myelin phagocytosis by macrophages; a structure-activity relationship study. Biochem Pharmacol 2003 0.93
41 Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases. Arch Toxicol 2014 0.92
42 Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier. J Neuroinflammation 2012 0.91
43 The extracellular matrix in multiple sclerosis pathology. J Neurochem 2007 0.91
44 T lymphocytes impair P-glycoprotein function during neuroinflammation. J Autoimmun 2009 0.90
45 P-glycoprotein acts as an immunomodulator during neuroinflammation. PLoS One 2009 0.90
46 NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions. Free Radic Biol Med 2006 0.90
47 Surgery-induced reactive oxygen species enhance colon carcinoma cell binding by disrupting the liver endothelial cell lining. Gut 2011 0.90
48 Brain endothelial barrier passage by monocytes is controlled by the endothelin system. J Neurochem 2011 0.89
49 Characteristics of dyshoric capillary cerebral amyloid angiopathy. J Neuropathol Exp Neurol 2010 0.89
50 Dynamics and fate of USPIO in the central nervous system in experimental autoimmune encephalomyelitis. NMR Biomed 2010 0.89
51 The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier. J Neurochem 2010 0.88
52 Neuroinflammation and blood-brain barrier changes in capillary amyloid angiopathy. Neurodegener Dis 2012 0.87
53 Protective effects of peroxiredoxin-1 at the injured blood-brain barrier. Free Radic Biol Med 2008 0.87
54 Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation. J Control Release 2012 0.87
55 Astrocyte-derived retinoic acid: a novel regulator of blood-brain barrier function in multiple sclerosis. Acta Neuropathol 2014 0.85
56 Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions. Glia 2014 0.85
57 MRI of ICAM-1 upregulation after stroke: the importance of choosing the appropriate target-specific particulate contrast agent. Mol Imaging Biol 2013 0.85
58 Dietary intake of plant sterols stably increases plant sterol levels in the murine brain. J Lipid Res 2012 0.84
59 Association of Parkinson disease-related protein PINK1 with Alzheimer disease and multiple sclerosis brain lesions. Free Radic Biol Med 2010 0.84
60 Involvement and interplay of Parkin, PINK1, and DJ1 in neurodegenerative and neuroinflammatory disorders. Free Radic Biol Med 2012 0.83
61 Magnetic resonance imaging of monocytes labeled with ultrasmall superparamagnetic particles of iron oxide using magnetoelectroporation in an animal model of multiple sclerosis. Mol Imaging 2010 0.83
62 Neuronal and axonal loss in normal-appearing gray matter and subpial lesions in multiple sclerosis. J Neuropathol Exp Neurol 2015 0.82
63 Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis. Acta Neuropathol Commun 2014 0.82
64 Immunoglobulin A: Fc(alpha)RI interactions induce neutrophil migration through release of leukotriene B4. Gastroenterology 2009 0.80
65 P-glycoprotein regulates trafficking of CD8(+) T cells to the brain parenchyma. Acta Neuropathol 2014 0.80
66 Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists. FASEB J 2013 0.79
67 PECAM-1-targeted micron-sized particles of iron oxide as MRI contrast agent for detection of vascular remodeling after cerebral ischemia. Contrast Media Mol Imaging 2013 0.79
68 Nanoclusters of iron oxide: effect of core composition on structure, biocompatibility, and cell labeling efficacy. Bioconjug Chem 2012 0.78
69 The Role of ATP-Binding Cassette Transporters in Neuro-Inflammation: Relevance for Bioactive Lipids. Front Pharmacol 2012 0.78
70 Roles for HB-EGF and CD9 in multiple sclerosis. Glia 2013 0.78
71 Discrepancy in CCL2 and CCR2 expression in white versus grey matter hippocampal lesions of Multiple Sclerosis patients. Acta Neuropathol Commun 2014 0.78
72 Soluble VCAM-1 impairs human brain endothelial barrier integrity via integrin α-4-transduced outside-in signalling. Acta Neuropathol 2015 0.78
73 Monocyte activation and disease activity in multiple sclerosis. A longitudinal analysis of serum MRP8/14 levels. J Neuroimmunol 2004 0.78
74 Disturbed function of the blood-cerebrospinal fluid barrier aggravates neuro-inflammation. Acta Neuropathol 2013 0.77
75 ATP-binding cassette transporters P-glycoprotein and breast cancer related protein are reduced in capillary cerebral amyloid angiopathy. Neurobiol Aging 2013 0.77
76 In vivo MR imaging of intercellular adhesion molecule-1 expression in an animal model of multiple sclerosis. Contrast Media Mol Imaging 2014 0.77
77 Mesenchymal stem cells are mobilized from the bone marrow during inflammation. Front Immunol 2013 0.77
78 Correction: Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction. PLoS One 2016 0.75
79 In Vitro and Ex Vivo Model Systems to Measure ABC Transporter Activity at the Blood-Brain Barrier. Curr Pharm Des 2016 0.75