Published in Free Radic Biol Med on April 16, 2008
Blood-brain barrier pathophysiology in traumatic brain injury. Transl Stroke Res (2011) 1.45
Astragaloside IV attenuates experimental autoimmune encephalomyelitis of mice by counteracting oxidative stress at multiple levels. PLoS One (2013) 0.98
Differential proteome analysis of human embryonic kidney cell line (HEK-293) following mycophenolic acid treatment. Proteome Sci (2011) 0.82
Microwave and magnetic (M(2) ) proteomics of the experimental autoimmune encephalomyelitis animal model of multiple sclerosis. Electrophoresis (2012) 0.81
Protective effects of andrographolide analogue AL-1 on ROS-induced RIN-mβ cell death by inducing ROS generation. PLoS One (2013) 0.80
Nitrosative stress induces peroxiredoxin 1 ubiquitination during ischemic insult via E6AP activation in endothelial cells both in vitro and in vivo. Antioxid Redox Signal (2014) 0.80
Deficiency of TDAG51 protects against atherosclerosis by modulating apoptosis, cholesterol efflux, and peroxiredoxin-1 expression. J Am Heart Assoc (2013) 0.79
Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels. BMC Complement Altern Med (2014) 0.77
Diagnostic performance of peroxiredoxin 1 to determine time-of-onset of acute cerebral infarction. Sci Rep (2016) 0.75
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science (2011) 3.52
Structure and function of claudins. Biochim Biophys Acta (2007) 2.98
The macrophage scavenger receptor CD163. Immunobiology (2005) 2.44
Formation of tight junction: determinants of homophilic interaction between classic claudins. FASEB J (2007) 2.43
Progressive multiple sclerosis: pathology and pathogenesis. Nat Rev Neurol (2012) 2.32
Homogeneity of active demyelinating lesions in established multiple sclerosis. Ann Neurol (2008) 2.29
The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria. Blood (2008) 1.96
Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease? Free Radic Biol Med (2008) 1.83
NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury. Brain (2012) 1.82
The pathology of multiple sclerosis is location-dependent: no significant complement activation is detected in purely cortical lesions. J Neuropathol Exp Neurol (2005) 1.76
Genetic analysis of the mouse brain proteome. Nat Genet (2002) 1.73
Macrophages and neurodegeneration. Brain Res Brain Res Rev (2005) 1.64
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling. FASEB J (2007) 1.63
Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status. J Neuroinflammation (2013) 1.59
Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells. J Am Soc Nephrol (2006) 1.50
Improved two-dimensional reversed phase-reversed phase LC-MS/MS approach for identification of peptide-protein interactions. J Proteome Res (2011) 1.45
Puromycin-purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction. J Neurochem (2006) 1.43
EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation. Proc Natl Acad Sci U S A (2008) 1.43
The tight junction protein occludin and the adherens junction protein alpha-catenin share a common interaction mechanism with ZO-1. J Biol Chem (2004) 1.42
Radical changes in multiple sclerosis pathogenesis. Biochim Biophys Acta (2010) 1.40
The molecular basis of neurodegeneration in multiple sclerosis. FEBS Lett (2011) 1.39
Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells. J Biol Chem (2004) 1.39
Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement. Brain (2008) 1.38
Interferon-beta directly influences monocyte infiltration into the central nervous system. J Neuroimmunol (2002) 1.35
Ratjadone and leptomycin B block CRM1-dependent nuclear export by identical mechanisms. FEBS Lett (2004) 1.35
Diapedesis of monocytes is associated with MMP-mediated occludin disappearance in brain endothelial cells. FASEB J (2006) 1.34
Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration? Mitochondrion (2010) 1.34
Flavonoids influence monocytic GTPase activity and are protective in experimental allergic encephalitis. J Exp Med (2004) 1.34
The blood-brain barrier and its role in immune privilege in the central nervous system. J Neuropathol Exp Neurol (2003) 1.32
Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity. J Immunol (2006) 1.30
The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes. Nucleic Acids Res (2011) 1.30
CD163-positive perivascular macrophages in the human CNS express molecules for antigen recognition and presentation. Glia (2005) 1.30
Enhanced number and activity of mitochondria in multiple sclerosis lesions. J Pathol (2009) 1.29
Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy. Antioxid Redox Signal (2011) 1.29
Comparison of SPIO and USPIO for in vitro labeling of human monocytes: MR detection and cell function. Radiology (2007) 1.28
Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endothelium. J Immunol (2002) 1.26
The rat macrophage scavenger receptor CD163: expression, regulation and role in inflammatory mediator production. Immunobiology (2006) 1.25
Fingolimod attenuates ceramide-induced blood-brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes. Acta Neuropathol (2012) 1.22
Interferon-beta prevents cytokine-induced neutrophil infiltration and attenuates blood-brain barrier disruption. J Cereb Blood Flow Metab (2003) 1.21
A K+-selective cGMP-gated ion channel controls chemosensation of sperm. Nat Cell Biol (2006) 1.21
The blood-brain barrier in cortical multiple sclerosis lesions. J Neuropathol Exp Neurol (2007) 1.20
An atypical CNG channel activated by a single cGMP molecule controls sperm chemotaxis. Sci Signal (2009) 1.20
Serum markers support disease-specific glial pathology in major depression. J Affect Disord (2008) 1.18
Proteomic analysis of adaptor protein 1A coats selectively assembled on liposomes. Proc Natl Acad Sci U S A (2006) 1.17
Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion. Proc Natl Acad Sci U S A (2010) 1.17
Retinoic acid induces blood-brain barrier development. J Neurosci (2013) 1.17
RhoA activation promotes transendothelial migration of monocytes via ROCK. J Leukoc Biol (2003) 1.16
Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions. Glia (2010) 1.15
Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation. Epilepsia (2012) 1.15
Proteomic analysis of lysosomal acid hydrolases secreted by osteoclasts: implications for lytic enzyme transport and bone metabolism. Mol Cell Proteomics (2005) 1.15
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis. Neurobiol Dis (2005) 1.14
Matrix metalloproteinase-12 is expressed in phagocytotic macrophages in active multiple sclerosis lesions. J Neuroimmunol (2003) 1.14
Elucidating the principles of the molecular organization of heteropolymeric tight junction strands. Cell Mol Life Sci (2011) 1.12
Identification of phosphorylation-dependent interaction partners of the adapter protein ADAP using quantitative mass spectrometry: SILAC vs (18)O-labeling. J Proteome Res (2010) 1.12
Molecular determinants of the interaction between Clostridium perfringens enterotoxin fragments and claudin-3. J Biol Chem (2009) 1.11
Actin remodeling requires ERM function to facilitate AQP2 apical targeting. J Cell Sci (2005) 1.10
Mass-spectrometric identification of a novel angiotensin peptide in human plasma. Arterioscler Thromb Vasc Biol (2006) 1.10
Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation. J Neuroinflammation (2012) 1.09
Protein networks supporting AP-3 function in targeting lysosomal membrane proteins. Mol Biol Cell (2008) 1.09
Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. Eur J Neurosci (2007) 1.08
Differential regulation of the CXCR2 chemokine network in rat brain trauma: implications for neuroimmune interactions and neuronal survival. Neurobiol Dis (2006) 1.08
Participation of the second extracellular loop of claudin-5 in paracellular tightening against ions, small and large molecules. Cell Mol Life Sci (2010) 1.07
MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis. J Neurosci (2013) 1.07
MRI of monocyte infiltration in an animal model of neuroinflammation using SPIO-labeled monocytes or free USPIO. J Cereb Blood Flow Metab (2007) 1.07
Ultrasound and microbubble-induced intra- and intercellular bioeffects in primary endothelial cells. Ultrasound Med Biol (2009) 1.07
Disease-causing V(2) vasopressin receptors are retained in different compartments of the early secretory pathway. Traffic (2004) 1.06
Galpha(s) is palmitoylated at the N-terminal glycine. EMBO J (2003) 1.06
SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function. Am J Physiol Heart Circ Physiol (2007) 1.05
CX(3)CR1 drives cytotoxic CD4(+)CD28(-) T cells into the brain of multiple sclerosis patients. J Autoimmun (2011) 1.05
Nucleocytoplasmic shuttling of the Golgi phosphatidylinositol 4-kinase Pik1 is regulated by 14-3-3 proteins and coordinates Golgi function with cell growth. Mol Biol Cell (2008) 1.05