Published in World Psychiatry on February 01, 2008
Removing obstacles in neuroscience drug discovery: the future path for animal models. Neuropsychopharmacology (2008) 2.16
Social approach in genetically engineered mouse lines relevant to autism. Genes Brain Behav (2008) 1.94
Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Eur J Hum Genet (2009) 1.38
Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders. Mol Psychiatry (2013) 1.16
Fine mapping of QTL for prepulse inhibition in LG/J and SM/J mice using F(2) and advanced intercross lines. Genes Brain Behav (2010) 1.03
A new role for endophenotypes in the GWAS era: functional characterization of risk variants. Harv Rev Psychiatry (2010) 1.00
Impact of ketamine on neuronal network dynamics: translational modeling of schizophrenia-relevant deficits. CNS Neurosci Ther (2013) 0.98
Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study. Psychophysiology (2010) 0.96
Consortium on the Genetics of Schizophrenia (COGS) assessment of endophenotypes for schizophrenia: an introduction to this Special Issue of Schizophrenia Research. Schizophr Res (2014) 0.95
Discrete forebrain neuronal networks supporting noradrenergic regulation of sensorimotor gating. Neuropsychopharmacology (2011) 0.93
Electroencephalography (EEG) and event-related potentials (ERPs) with human participants. Curr Protoc Neurosci (2010) 0.89
Neuropsychological impairments predict the clinical course in schizophrenia. Eur Arch Psychiatry Clin Neurosci (2008) 0.88
Enduring sensorimotor gating abnormalities following predator exposure or corticotropin-releasing factor in rats: a model for PTSD-like information-processing deficits? Neuropharmacology (2011) 0.88
Genome-wide scans of genetic variants for psychophysiological endophenotypes: a methodological overview. Psychophysiology (2014) 0.87
Ventral striatal noradrenergic mechanisms contribute to sensorimotor gating deficits induced by amphetamine. Neuropsychopharmacology (2010) 0.86
Cross-diagnostic comparison of duration mismatch negativity and P3a in bipolar disorder and schizophrenia. Bipolar Disord (2012) 0.85
Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia. Arch Gen Psychiatry (2011) 0.85
The clinical staging and the endophenotype approach as an integrative future perspective for psychiatry. World Psychiatry (2008) 0.84
Heritability and molecular genetic basis of antisaccade eye tracking error rate: a genome-wide association study. Psychophysiology (2014) 0.84
Functional genetic variants in the vesicular monoamine transporter 1 modulate emotion processing. Mol Psychiatry (2013) 0.81
Mutual independence of 5-HT(2) and α1 noradrenergic receptors in mediating deficits in sensorimotor gating. Psychopharmacology (Berl) (2011) 0.80
Fos expression following regimens of predator stress versus footshock that differentially affect prepulse inhibition in rats. Physiol Behav (2011) 0.77
Inhibition of the cortex using transcranial magnetic stimulation in psychiatric populations: current and future directions. J Psychiatry Neurosci (2012) 0.77
From Linkage Studies to Epigenetics: What We Know and What We Need to Know in the Neurobiology of Schizophrenia. Front Neurosci (2016) 0.77
Strategies for the study of neuropsychiatric disorders using endophenotypes in developing countries: a potential databank from china. Front Hum Neurosci (2010) 0.77
P300 and neuropsychological measurements in patients with schizophrenia and their healthy biological siblings. Indian J Psychiatry (2017) 0.75
Neurophyisological and neurocognitive endophenotypes for schizophrenia genetics research. Psychiatry Investig (2008) 0.75
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry (2003) 21.70
Replicating genotype-phenotype associations. Nature (2007) 16.11
Principal stratification in causal inference. Biometrics (2002) 12.34
Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry (2005) 9.23
Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology (1998) 8.73
Schizophrenia: a common disease caused by multiple rare alleles. Br J Psychiatry (2007) 7.00
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial. Arch Gen Psychiatry (2007) 5.64
Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci U S A (1997) 4.89
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. J Neurosci (1999) 4.56
Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) (2001) 4.52
Sensorimotor gating and schizophrenia. Human and animal model studies. Arch Gen Psychiatry (1990) 4.08
Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia. Am J Hum Genet (2002) 4.03
Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berl) (2001) 4.03
Neuropsychological function in schizophrenia. Selective impairment in memory and learning. Arch Gen Psychiatry (1991) 3.88
Memory impairment in schizophrenia: a meta-analysis. Am J Psychiatry (1999) 3.69
Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia. Arch Gen Psychiatry (1994) 3.59
Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypes. Schizophr Bull (2005) 3.36
Prestimulus effects on human startle reflex in normals and schizophrenics. Psychophysiology (1978) 3.08
A unitary model of schizophrenia: Bleuler's "fragmented phrene" as schizencephaly. Arch Gen Psychiatry (1999) 2.93
Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures. Schizophr Bull (2006) 2.92
Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch Gen Psychiatry (2007) 2.91
Computerized neurocognitive scanning: I. Methodology and validation in healthy people. Neuropsychopharmacology (2001) 2.70
Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia. Arch Gen Psychiatry (2006) 2.63
Cognitive deficits in relatives of patients with schizophrenia: a meta-analysis. Schizophr Res (2004) 2.61
Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia. Biol Psychiatry (1982) 2.60
The endophenotype concept in psychiatric genetics. Psychol Med (2006) 2.49
Information processing and attentional functioning in the developmental course of schizophrenic disorders. Schizophr Bull (1984) 2.48
Auditory working memory and Wisconsin Card Sorting Test performance in schizophrenia. Arch Gen Psychiatry (1997) 2.48
Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr Bull (2006) 2.46
Disorders of attention and perception in early schizophrenia. Br J Med Psychol (1961) 2.44
Genetic theorizing and schizophrenia. Br J Psychiatry (1973) 2.30
Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: a magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins. Am J Psychiatry (1992) 2.27
Impaired attention, genetics, and the pathophysiology of schizophrenia. Schizophr Bull (1994) 2.18
Normalization of auditory physiology by cigarette smoking in schizophrenic patients. Am J Psychiatry (1993) 2.17
Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome. Proc Natl Acad Sci U S A (2006) 2.03
Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice. Mol Psychiatry (2004) 2.00
Computerized neurocognitive scanning: II. The profile of schizophrenia. Neuropsychopharmacology (2001) 1.97
Information processing and attention dysfunctions in schizophrenia. Schizophr Bull (1993) 1.91
The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophr Bull (2006) 1.88
Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function. Arch Gen Psychiatry (2006) 1.78
Attention, memory, and motor skills as childhood predictors of schizophrenia-related psychoses: the New York High-Risk Project. Am J Psychiatry (2000) 1.77
Verbal declarative memory dysfunction in schizophrenia: from clinical assessment to genetics and brain mechanisms. Neuropsychol Rev (2003) 1.71
Spatial working memory deficits in the relatives of schizophrenic patients. Arch Gen Psychiatry (1995) 1.69
Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease. J Neurol Neurosurg Psychiatry (1995) 1.64
Molecular genetic studies of schizophrenia. Eur J Hum Genet (2006) 1.64
Deficits in sensory gating in schizophrenic patients and their relatives. Evidence obtained with auditory evoked responses. Arch Gen Psychiatry (1984) 1.63
Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: evidence of inhibitory deficits. Am J Psychiatry (2000) 1.60
Childhood developmental abnormalities in schizophrenia: evidence from high-risk studies. Schizophr Res (2003) 1.60
Cognitive and behavioral precursors of schizophrenia. Dev Psychopathol (1999) 1.60
Neurophysiological evidence for a defect in inhibitory pathways in schizophrenia: comparison of medicated and drug-free patients. Biol Psychiatry (1983) 1.55
Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia. Schizophr Res (2001) 1.54
Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics. Biol Psychiatry (1992) 1.53
Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophr Bull (1998) 1.53
The continuous performance test, identical pairs version: II. Contrasting attentional profiles in schizophrenic and depressed patients. Psychiatry Res (1989) 1.47
Neurobiological studies of sensory gating in schizophrenia. Schizophr Bull (1987) 1.44
Thalamic and amygdala-hippocampal volume reductions in first-degree relatives of patients with schizophrenia: an MRI-based morphometric analysis. Biol Psychiatry (1999) 1.39
Genetics of schizophrenia and the new millennium: progress and pitfalls. Am J Hum Genet (2001) 1.33
Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia. Am J Hum Genet (2006) 1.30
Information-processing deficits and thought disorder in schizophrenia. Am J Psychiatry (1994) 1.27
Identification of the phenotype in psychiatric genetics. Eur Arch Psychiatry Clin Neurosci (1993) 1.27
Neuropsychological functioning in adolescents and young adults at genetic risk for schizophrenia and affective psychoses: results from the Harvard and Hillside Adolescent High Risk Studies. Schizophr Bull (2006) 1.26
Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophr Res (2006) 1.25
Lower prepulse inhibition in children with the 22q11 deletion syndrome. Am J Psychiatry (2005) 1.25
Neurocognitive assessment in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project schizophrenia trial: development, methodology, and rationale. Schizophr Bull (2003) 1.24
Working memory in schizophrenia: transient "online" storage versus executive functioning. Schizophr Bull (2001) 1.19
The person-key to understanding mental illness: towards a new dynamic psychiatry, III. Br J Psychiatry Suppl (1992) 1.19
Schizophrenia risk and paternal age: a potential role for de novo mutations in schizophrenia vulnerability genes. CNS Spectr (2002) 1.17
Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia. Schizophr Res (2007) 1.11
Contributions of clinical neuropsychology to the study of schizophrenia. J Abnorm Psychol (1989) 1.11
Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder. Am J Psychiatry (1993) 1.07
P50 suppression among schizophrenia and normal comparison subjects: a methodological analysis. Biol Psychiatry (1997) 1.05
Schizophrenic individuals' cognitive functioning and performance in interpersonal interactions and skills training procedures. J Psychiatr Res (1994) 1.02
Auditory sensory gating, hippocampal volume, and catecholamine metabolism in schizophrenics and their siblings. Schizophr Res (1994) 1.01
Voluntary control of saccadic eye movements in patients with schizophrenic and affective disorders. J Psychiatr Res (1990) 1.01
Preliminary evidence of an association between sensorimotor gating and distractibility in psychosis. J Neuropsychiatry Clin Neurosci (1996) 0.97
Glucose metabolic rate in normals and schizophrenics during the Continuous Performance Test assessed by positron emission tomography. Br J Psychiatry (1990) 0.92
Schizophrenia: new phenes and new genes. Biol Psychiatry (1999) 0.86
Attention dysfunction in chronic schizophrenia. Arch Gen Psychiatry (1966) 0.86
Relationships between neuropsychological and oculomotor measures in schizophrenia patients and normal controls. Biol Psychiatry (1997) 0.85
Distractibility in children vulnerable to psychopathology. J Abnorm Psychol (1981) 0.82
The effects of increasing resource demand on vigilance performance in adults with schizophrenia or developmental attentional/learning disorders: a preliminary study. Schizophr Res (1998) 0.81
Attention deficits assessed by Continuous Performance Test and Span of Apprehension Test in Japanese schizophrenic patients. Schizophr Res (1997) 0.80
Attentional and neuromotor functions of schizophrenics, schizoaffectives, and patients with other affective disorders. Arch Gen Psychiatry (1981) 0.78
Sequential genome-wide association studies for monitoring adverse events in the clinical evaluation of new drugs. Stat Med (2006) 0.77
Human genetic variation and its contribution to complex traits. Nat Rev Genet (2009) 12.11
Evaluation of next generation sequencing platforms for population targeted sequencing studies. Genome Biol (2009) 9.59
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Identification of ALK as a major familial neuroblastoma predisposition gene. Nature (2008) 7.38
Effect of direct-to-consumer genomewide profiling to assess disease risk. N Engl J Med (2011) 6.90
Statistical analysis strategies for association studies involving rare variants. Nat Rev Genet (2010) 6.79
Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial. JAMA (2011) 6.39
The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell (2002) 4.72
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet (2004) 4.51
Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology (2005) 4.21
Pathway analysis of seven common diseases assessed by genome-wide association. Genomics (2008) 4.11
Accommodating linkage disequilibrium in genetic-association analyses via ridge regression. Am J Hum Genet (2008) 3.86
Generalized genomic distance-based regression methodology for multilocus association analysis. Am J Hum Genet (2006) 3.79
Transgenerational epigenetic instability is a source of novel methylation variants. Science (2011) 3.66
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network. Cell (2013) 3.26
Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients. Ann Intern Med (2010) 3.17
Heritability of nonalcoholic fatty liver disease. Gastroenterology (2009) 3.17
Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures. Schizophr Bull (2006) 2.92
Characterization of circulating endothelial cells in acute myocardial infarction. Sci Transl Med (2012) 2.91
Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch Gen Psychiatry (2007) 2.91
Accurate detection and genotyping of SNPs utilizing population sequencing data. Genome Res (2010) 2.84
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity. Aging Cell (2009) 2.79
A genome-wide linkage analysis investigating the determinants of blood pressure in whites and African Americans. Am J Hypertens (2003) 2.76
Patterns of population epigenomic diversity. Nature (2013) 2.70
Methods for handling multiple testing. Adv Genet (2008) 2.67
Realistic expectations of prepulse inhibition in translational models for schizophrenia research. Psychopharmacology (Berl) (2008) 2.64
Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr Bull (2006) 2.46
The n-of-1 clinical trial: the ultimate strategy for individualizing medicine? Per Med (2011) 2.43
Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet (2005) 2.41
The importance of phase information for human genomics. Nat Rev Genet (2011) 2.25
Gamma band oscillations reveal neural network cortical coherence dysfunction in schizophrenia patients. Biol Psychiatry (2006) 2.25
Consumer perceptions of direct-to-consumer personalized genomic risk assessments. Genet Med (2010) 2.23
CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. Proc Natl Acad Sci U S A (2011) 2.23
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Kinase mutations in human disease: interpreting genotype-phenotype relationships. Nat Rev Genet (2010) 2.14
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. PLoS Genet (2013) 2.08
A covering method for detecting genetic associations between rare variants and common phenotypes. PLoS Comput Biol (2010) 1.98
Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Hum Genet (2006) 1.98
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet (2012) 1.96
Heritability estimates for dental caries and sucrose sweetness preference. Arch Oral Biol (2006) 1.96
Multivariate regression analysis of distance matrices for testing associations between gene expression patterns and related variables. Proc Natl Acad Sci U S A (2006) 1.95
Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry (2011) 1.93
Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo. Circulation (2007) 1.91
The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophr Bull (2006) 1.88
Impact of direct-to-consumer genomic testing at long term follow-up. J Med Genet (2013) 1.86
Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet (2006) 1.86
Generalized analysis of molecular variance. PLoS Genet (2007) 1.85
DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies. Genome Biol (2007) 1.84
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations. Proc Natl Acad Sci U S A (2009) 1.84
A comprehensive literature review of haplotyping software and methods for use with unrelated individuals. Hum Genomics (2005) 1.84
Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia. Genome Res (2010) 1.83
Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. Am J Hum Genet (2006) 1.82
Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function. Arch Gen Psychiatry (2006) 1.78
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum Mol Genet (2012) 1.77
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study. PLoS Genet (2010) 1.76
Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders. Neuropsychopharmacology (2007) 1.71
Chromogranin A polymorphisms are associated with hypertensive renal disease. J Am Soc Nephrol (2008) 1.68
G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions. Am J Hypertens (2009) 1.66
Identification of EpCAM as the gene for congenital tufting enteropathy. Gastroenterology (2008) 1.65
Population-based sample reveals gene-gender interactions in blood pressure in White Americans. Hypertension (2006) 1.64
Direct-to-consumer personalized genomic testing. Hum Mol Genet (2011) 1.61
Direct-to-consumer pharmacogenomic testing is associated with increased physician utilisation. J Med Genet (2013) 1.61
Prediction of cancer driver mutations in protein kinases. Cancer Res (2008) 1.59
Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology. Am J Hum Genet (2004) 1.58
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Sex-dependent association of common variants of microcephaly genes with brain structure. Proc Natl Acad Sci U S A (2009) 1.55
RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways. Neuron (2003) 1.53
Genetic variation at the human alpha2B-adrenergic receptor locus: role in blood pressure variation and yohimbine response. Hypertension (2005) 1.52
Identifying genes and genetic variation underlying human diseases and complex phenotypes via recombination mapping. J Physiol (2004) 1.52
Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins. Physiol Genomics (2004) 1.51
Multimodal imaging of the self-regulating developing brain. Proc Natl Acad Sci U S A (2012) 1.49
Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis. Nephrol Dial Transplant (2009) 1.49
Preattentional and attentional cognitive deficits as targets for treating schizophrenia. Psychopharmacology (Berl) (2004) 1.47
Identification of rare cancer driver mutations by network reconstruction. Genome Res (2009) 1.47
Gain-of-function ADCY5 mutations in familial dyskinesia with facial myokymia. Ann Neurol (2014) 1.47
Altered DNA methylation in leukocytes with trisomy 21. PLoS Genet (2010) 1.44
A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. J Immunol (2002) 1.41
KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST). Pharmacogenet Genomics (2007) 1.40
Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease. Hum Mol Genet (2005) 1.38
Efficient and cost effective population resequencing by pooling and in-solution hybridization. PLoS One (2011) 1.38
Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet (2012) 1.37
Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch. PLoS Genet (2008) 1.36
Extremes of unexplained variation as a phenotype: an efficient approach for genome-wide association studies of cardiovascular disease. Circ Cardiovasc Genet (2010) 1.33
Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension. Circulation (2007) 1.32
Large-scale integration of human genetic and physical maps. Genome Res (2004) 1.32
A polymorphism of the beta1-adrenergic receptor is associated with low extraversion. Biol Psychiatry (2004) 1.32
Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry (2013) 1.30