Published in Proc Natl Acad Sci U S A on August 26, 2009
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The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception. Alzheimers Dement (2013) 2.32
Hierarchical genetic organization of human cortical surface area. Science (2012) 2.28
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The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90
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False positives in neuroimaging genetics using voxel-based morphometry data. Neuroimage (2010) 1.39
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Sex and age differences in atrophic rates: an ADNI study with n=1368 MRI scans. Neurobiol Aging (2010) 1.30
Measuring and comparing brain cortical surface area and other areal quantities. Neuroimage (2012) 1.27
Dynamic Development of Regional Cortical Thickness and Surface Area in Early Childhood. Cereb Cortex (2014) 1.22
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Genetic and environmental contributions to regional cortical surface area in humans: a magnetic resonance imaging twin study. Cereb Cortex (2011) 1.13
Increasing power for voxel-wise genome-wide association studies: the random field theory, least square kernel machines and fast permutation procedures. Neuroimage (2012) 1.05
Boosting the power of schizophrenia genetics by leveraging new statistical tools. Schizophr Bull (2013) 1.03
The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository. Neuroimage (2015) 0.99
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A (2012) 0.95
Topological properties of large-scale structural brain networks in children with familial risk for reading difficulties. Neuroimage (2013) 0.94
Structural abnormalities in cortical volume, thickness, and surface area in 22q11.2 microdeletion syndrome: Relationship with psychotic symptoms. Neuroimage Clin (2013) 0.93
Adolescent brain maturation and cortical folding: evidence for reductions in gyrification. PLoS One (2014) 0.92
The rise of large-scale imaging studies in psychiatry. Gigascience (2014) 0.91
Postnatal brain development: structural imaging of dynamic neurodevelopmental processes. Prog Brain Res (2011) 0.90
Comparing connectivity pattern and small-world organization between structural correlation and resting-state networks in healthy adults. Neuroimage (2013) 0.90
Common variants on Xq28 conferring risk of schizophrenia in Han Chinese. Schizophr Bull (2013) 0.90
Distinct abnormalities of the primate prefrontal cortex caused by ionizing radiation in early or midgestation. J Comp Neurol (2013) 0.89
DNA modifications: function and applications in normal and disease States. Biology (Basel) (2014) 0.88
Fast identification of biological pathways associated with a quantitative trait using group lasso with overlaps. Stat Appl Genet Mol Biol (2012) 0.87
Genomic imprinting effects of the X chromosome on brain morphology. J Neurosci (2013) 0.86
Neural population tuning links visual cortical anatomy to human visual perception. Neuron (2015) 0.83
CETP polymorphisms associate with brain structure, atrophy rate, and Alzheimer's disease risk in an APOE-dependent manner. Brain Imaging Behav (2012) 0.83
Mild expression differences of MECP2 influencing aggressive social behavior. EMBO Mol Med (2014) 0.82
A geographic cline of skull and brain morphology among individuals of European Ancestry. Hum Hered (2011) 0.81
Cortical surface area correlates with STON2 gene Ser307Pro polymorphism in first-episode treatment-naïve patients with schizophrenia. PLoS One (2013) 0.80
Aberrant Cortical Morphometry in the 22q11.2 Deletion Syndrome. Biol Psychiatry (2014) 0.80
Morphological abnormalities in prefrontal surface area and thalamic volume in attention deficit/hyperactivity disorder. Psychiatry Res (2015) 0.80
Reduced cortical surface area in adolescents with conduct disorder. Eur Child Adolesc Psychiatry (2014) 0.79
Neurogenetic effects on cognition in aging brains: a window of opportunity for intervention? Front Aging Neurosci (2010) 0.78
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Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology. Front Mol Neurosci (2017) 0.75
The Imaging and Cognition Genetics Conference 2011, ICG 2011: A Meeting of Minds. Front Neurosci (2012) 0.75
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Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
A haplotype map of the human genome. Nature (2005) 105.70
A map of recent positive selection in the human genome. PLoS Biol (2006) 29.19
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet (1999) 22.84
MeCP2, a key contributor to neurological disease, activates and represses transcription. Science (2008) 10.11
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science (2002) 7.92
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell (1998) 6.79
Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens. Science (2005) 5.55
Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous. Hum Hered (2003) 5.06
Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans. Science (2005) 4.79
PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects. Nat Genet (1994) 4.38
Global landscape of recent inferred Darwinian selection for Homo sapiens. Proc Natl Acad Sci U S A (2005) 3.77
Abnormal functional connectivity in autism spectrum disorders during face processing. Brain (2008) 2.75
Role of intermediate progenitor cells in cerebral cortex development. Dev Neurosci (2008) 2.66
Language-association cortex asymmetry in autism and specific language impairment. Ann Neurol (2004) 2.49
Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation. Epigenetics (2007) 2.30
Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis. Nat Genet (2007) 2.03
Behavioral and anatomical abnormalities in Mecp2 mutant mice: a model for Rett syndrome. Neuroscience (2007) 1.88
Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans. Hum Mol Genet (2004) 1.61
The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells. J Neurobiol (2003) 1.58
Brain development in autism: early overgrowth followed by premature arrest of growth. Ment Retard Dev Disabil Res Rev (2004) 1.52
MECP2 structural and 3'-UTR variants in schizophrenia, autism and other psychiatric diseases: a possible association with autism. Am J Med Genet B Neuropsychiatr Genet (2004) 1.51
Early progressive encephalopathy in boys and MECP2 mutations. Neurology (2006) 1.44
MeCP2 mutations in children with and without the phenotype of Rett syndrome. Neurology (2001) 1.36
Molecular genetics of Rett syndrome and clinical spectrum of MECP2 mutations. Curr Opin Neurol (2001) 1.30
Comparative study of brain morphology in Mecp2 mutant mouse models of Rett syndrome. J Comp Neurol (2008) 1.26
Gait function in newly diagnosed children with autism: Cerebellar and basal ganglia related motor disorder. Dev Med Child Neurol (2006) 1.26
Severe congenital encephalopathy caused by MECP2 null mutations in males: central hypoxia and reduced neuronal dendritic structure. Clin Genet (2008) 1.26
Sex difference in mecp2 expression during a critical period of rat brain development. Epigenetics (2007) 1.22
Identification of cis-regulatory elements for MECP2 expression. Hum Mol Genet (2006) 1.18
MeCP2 dysfunction in humans and mice. J Child Neurol (2005) 1.15
Morphological study of neocortical areas in Rett syndrome. Acta Neuropathol (1997) 1.10
Mutation analysis of the coding sequence of the MECP2 gene in infantile autism. Hum Genet (2002) 1.06
Methyl-CpG-binding protein 2 polymorphisms and vulnerability to autism. Genes Brain Behav (2008) 1.05
Selective cerebral volume reduction in Rett syndrome: a multiple-approach MR imaging study. AJNR Am J Neuroradiol (2007) 1.01
MECP2 coding sequence and 3'UTR variation in 172 unrelated autistic patients. Am J Med Genet B Neuropsychiatr Genet (2007) 0.99
Absence of MeCP2 mutations in patients from the South Carolina autism project. Am J Med Genet B Neuropsychiatr Genet (2003) 0.92
Methyl-CpG-binding protein 2 is localized in the postsynaptic compartment: an immunochemical study of subcellular fractions. Neuroscience (2003) 0.90
Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia. Psychiatr Genet (2008) 0.83
Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron (2002) 33.99
An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage (2006) 25.52
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
Automatically parcellating the human cerebral cortex. Cereb Cortex (2004) 18.32
Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med (2006) 18.25
Assessing the impact of population stratification on genetic association studies. Nat Genet (2004) 16.28
The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods. J Magn Reson Imaging (2008) 14.68
Human genetic variation and its contribution to complex traits. Nat Rev Genet (2009) 12.11
Sequence-independent segmentation of magnetic resonance images. Neuroimage (2004) 11.36
Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial. JAMA (2002) 11.06
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med (2012) 10.16
Evaluation of next generation sequencing platforms for population targeted sequencing studies. Genome Biol (2009) 9.59
Thinning of the cerebral cortex in aging. Cereb Cortex (2004) 8.31
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature (2012) 8.10
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Identification of ALK as a major familial neuroblastoma predisposition gene. Nature (2008) 7.38
Effect of direct-to-consumer genomewide profiling to assess disease risk. N Engl J Med (2011) 6.90
Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet (2003) 6.85
Common vs. rare allele hypotheses for complex diseases. Curr Opin Genet Dev (2009) 6.85
Prevalence of conventional risk factors in patients with coronary heart disease. JAMA (2003) 6.84
Statistical analysis strategies for association studies involving rare variants. Nat Rev Genet (2010) 6.79
Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial. JAMA (2011) 6.39
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature (2011) 6.25
Prognostic value of myeloperoxidase in patients with chest pain. N Engl J Med (2003) 5.89
A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol (2003) 5.51
Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet (2003) 5.34
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet (2004) 5.31
Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes. JAMA (2004) 5.11
Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials. Lancet (2002) 5.04
Medial temporal lobe function and structure in mild cognitive impairment. Ann Neurol (2004) 4.89
Regionally localized thinning of the cerebral cortex in schizophrenia. Arch Gen Psychiatry (2003) 4.84
Microdroplet-based PCR enrichment for large-scale targeted sequencing. Nat Biotechnol (2009) 4.80
Disruption of the neurexin 1 gene is associated with schizophrenia. Hum Mol Genet (2008) 4.78
Can mobile health technologies transform health care? JAMA (2013) 4.75
The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell (2002) 4.72
Critical issues in peripheral arterial disease detection and management: a call to action. Arch Intern Med (2003) 4.72
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet (2004) 4.51
A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genet (2005) 4.45
Protein carbamylation links inflammation, smoking, uremia and atherogenesis. Nat Med (2007) 4.30
Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus. JAMA (2005) 4.23
Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology (2005) 4.21
Dorsal anterior cingulate cortex: a role in reward-based decision making. Proc Natl Acad Sci U S A (2001) 4.20
Pathway analysis of seven common diseases assessed by genome-wide association. Genomics (2008) 4.11
Treatment-resistant bipolar depression: a randomized controlled trial of electroconvulsive therapy versus algorithm-based pharmacological treatment. Am J Psychiatry (2014) 3.98
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Accommodating linkage disequilibrium in genetic-association analyses via ridge regression. Am J Hum Genet (2008) 3.86
Longitudinal stability of MRI for mapping brain change using tensor-based morphometry. Neuroimage (2006) 3.85
Generalized genomic distance-based regression methodology for multilocus association analysis. Am J Hum Genet (2006) 3.79
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Transgenerational epigenetic instability is a source of novel methylation variants. Science (2011) 3.66
Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. JAMA (2008) 3.64
Effects of age on volumes of cortex, white matter and subcortical structures. Neurobiol Aging (2005) 3.63
Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy. Neuroimage (2004) 3.48
Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial. Circulation (2003) 3.38
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Mutation of MEF2A in an inherited disorder with features of coronary artery disease. Science (2003) 3.34
Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients. Ann Intern Med (2010) 3.17
Heritability of nonalcoholic fatty liver disease. Gastroenterology (2009) 3.17
Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation. Neuroimage (2007) 3.07
Analysis of risk of bleeding complications after different doses of aspirin in 192,036 patients enrolled in 31 randomized controlled trials. Am J Cardiol (2005) 3.05
Troponin T levels in patients with acute coronary syndromes, with or without renal dysfunction. N Engl J Med (2002) 3.01
Economic evaluation of bivalirudin with provisional glycoprotein IIB/IIIA inhibition versus heparin with routine glycoprotein IIB/IIIA inhibition for percutaneous coronary intervention: results from the REPLACE-2 trial. J Am Coll Cardiol (2004) 2.97
A comprehensive family-based replication study of schizophrenia genes. JAMA Psychiatry (2013) 2.93
Characterization of circulating endothelial cells in acute myocardial infarction. Sci Transl Med (2012) 2.91
Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch Gen Psychiatry (2007) 2.91
Alzheimer disease: quantitative structural neuroimaging for detection and prediction of clinical and structural changes in mild cognitive impairment. Radiology (2009) 2.90
Arthritis medicines and cardiovascular events--"house of coxibs". JAMA (2004) 2.89
Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative. Alzheimers Dement (2010) 2.88
High consistency of regional cortical thinning in aging across multiple samples. Cereb Cortex (2009) 2.88