Published in Sheng Wu Gong Cheng Xue Bao on February 01, 2008
A global map of p53 transcription-factor binding sites in the human genome. Cell (2006) 20.65
ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature (2009) 18.38
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science (2009) 9.29
Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell (2005) 9.01
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell (2008) 7.79
Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, phase 3 trial. Lancet (2010) 7.11
Metagenomic discovery of biomass-degrading genes and genomes from cow rumen. Science (2011) 6.93
Generation of gene-modified mice via Cas9/RNA-mediated gene targeting. Cell Res (2013) 6.89
Adaptive particle swarm optimization. IEEE Trans Syst Man Cybern B Cybern (2009) 6.47
Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res (2009) 6.43
Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection. Lancet (2003) 5.99
Whole-genome cartography of estrogen receptor alpha binding sites. PLoS Genet (2007) 5.85
Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science (2006) 5.52
Activation and signaling of the p38 MAP kinase pathway. Cell Res (2005) 5.48
ChIP-Seq identification of weakly conserved heart enhancers. Nat Genet (2010) 4.32
PRAK is essential for ras-induced senescence and tumor suppression. Cell (2007) 4.30
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol (2003) 4.15
Arabidopsis interdigitating cell growth requires two antagonistic pathways with opposing action on cell morphogenesis. Cell (2005) 3.90
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science (2013) 3.90
MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha. Science (2002) 3.78
TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. Immunity (2002) 3.46
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity (2007) 3.38
Breast cancer detection based on incremental biochemical and physiological properties of breast cancers: a six-year, two-site study. Acad Radiol (2005) 3.33
Respiratory morbidity in late preterm births. JAMA (2010) 3.11
A global reference for fetal-weight and birthweight percentiles. Lancet (2011) 3.05
Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science (2013) 2.95
Macrosomia in 23 developing countries: an analysis of a multicountry, facility-based, cross-sectional survey. Lancet (2013) 2.89
The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating. Proc Natl Acad Sci U S A (2008) 2.82
Size distributions of maternal and fetal DNA in maternal plasma. Clin Chem (2004) 2.79
Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways. Immunity (2008) 2.62
Rnnotator: an automated de novo transcriptome assembly pipeline from stranded RNA-Seq reads. BMC Genomics (2010) 2.62
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13. Cell (2011) 2.58
A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the treatment of nasopharyngeal carcinoma. Radiother Oncol (2012) 2.54
Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria. Circ Res (2003) 2.52
Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes. Mol Biol Cell (2004) 2.50
Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C. Nat Med (2004) 2.45
Induction of bilirubin clearance by the constitutive androstane receptor (CAR). Proc Natl Acad Sci U S A (2003) 2.44
Labor progression and risk of cesarean delivery in electively induced nulliparas. Obstet Gynecol (2005) 2.44
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder. J ECT (2012) 2.43
Electronic origin of high-temperature superconductivity in single-layer FeSe superconductor. Nat Commun (2012) 2.37
Phase diagram and electronic indication of high-temperature superconductivity at 65 K in single-layer FeSe films. Nat Mater (2013) 2.34
Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A (2009) 2.33
The research implications of the selection of a gestational age estimation method. Paediatr Perinat Epidemiol (2007) 2.29
Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway. Genes Cells (2003) 2.28
Direct-method SAD phasing of proteins enhanced by the use of intrinsic bimodal phase distributions in the subsequent phase-improvement process. Acta Crystallogr D Biol Crystallogr (2009) 2.28
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell Res (2013) 2.26
The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. Nat Immunol (2003) 2.26
TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell (2012) 2.24
Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3. Neuron (2004) 2.23
XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization. Mol Cell (2007) 2.21
Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma. Am J Gastroenterol (2010) 2.20
Mapping the murine cardiac 26S proteasome complexes. Circ Res (2006) 2.17
Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels. Neuron (2004) 2.17
Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. Cell (2013) 2.16
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18. J Biol Chem (2012) 2.16
Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways. J Biol Chem (2004) 2.16
Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice. J Clin Invest (2008) 2.15
APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity. Curr Biol (2004) 2.09
p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation. Cell (2006) 2.06
Bacterial vaginosis assessed by gram stain and diminished colonization resistance to incident gonococcal, chlamydial, and trichomonal genital infection. J Infect Dis (2010) 2.02
Identification of suitable reference genes for qPCR analysis of serum microRNA in gastric cancer patients. Dig Dis Sci (2011) 2.02
Effects of dietary sodium and genetic background on angiotensinogen and Renin in mouse. Hypertension (2002) 2.00
Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: a systematic review. Am J Clin Nutr (2009) 2.00
Single-atom catalysis of CO oxidation using Pt1/FeOx. Nat Chem (2011) 1.98
Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clin Cancer Res (2010) 1.96
Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium. Toxicol Sci (2007) 1.94
Hidden dynamic allostery in a PDZ domain. Proc Natl Acad Sci U S A (2009) 1.93
Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival. Nature (2008) 1.91
Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Mol Cancer Ther (2007) 1.90
Role of the constitutive androstane receptor in xenobiotic-induced thyroid hormone metabolism. Endocrinology (2004) 1.89
Drag reduction through self-similar bending of a flexible body. Nature (2002) 1.89
Dynamic morphology of clear corneal cataract incisions. Ophthalmology (2003) 1.88
Autophagy contributes to caspase-independent macrophage cell death. J Biol Chem (2006) 1.87
Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. J Biol Chem (2006) 1.86
Seroprevalence of hepatitis E virus infection, rural southern People's Republic of China. Emerg Infect Dis (2006) 1.84
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. Science (2012) 1.84
Using a simplified Bishop score to predict vaginal delivery. Obstet Gynecol (2011) 1.83
The airborne metagenome in an indoor urban environment. PLoS One (2008) 1.81
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. J Clin Invest (2009) 1.80
Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor. Mol Endocrinol (2005) 1.79
Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation. EMBO J (2004) 1.79
Comparative study of four time series methods in forecasting typhoid fever incidence in China. PLoS One (2013) 1.78
Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins. Immunity (2010) 1.78
Swine as a principal reservoir of hepatitis E virus that infects humans in eastern China. J Infect Dis (2006) 1.78
Molecular interactions of CCR5 with major classes of small-molecule anti-HIV CCR5 antagonists. Mol Pharmacol (2007) 1.77
Papillary thyroid carcinoma with prominent hobnail features: a new aggressive variant of moderately differentiated papillary carcinoma. A clinicopathologic, immunohistochemical, and molecular study of eight cases. Am J Surg Pathol (2010) 1.76
Maternal prepregnancy overweight and obesity and the pattern of labor progression in term nulliparous women. Obstet Gynecol (2004) 1.76
Identification of ancient remains through genomic sequencing. Genome Res (2008) 1.72
Vulvovaginal symptoms in women with bacterial vaginosis. Obstet Gynecol (2004) 1.72
catena-Poly[[(acetato-κO,O')(methanol-κO)cadmium(II)]-μ-[1,2-bis-(1H-benzimid-azol-2-yl)ethane]-κN:N-[(acetato-κO,O')(methanol-κO)cadmium(II)]-di-μ-chlorido]. Acta Crystallogr Sect E Struct Rep Online (2010) 1.72
Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity. Cancer Res (2010) 1.71
A national estimate of the elective primary cesarean delivery rate. Obstet Gynecol (2005) 1.69
Oscillatory ROP GTPase activation leads the oscillatory polarized growth of pollen tubes. Mol Biol Cell (2005) 1.69
Withaferin A targets heat shock protein 90 in pancreatic cancer cells. Biochem Pharmacol (2010) 1.69
Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation. J Immunol (2008) 1.68
Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase. J Biol Chem (2002) 1.67
Interval between palliative care referral and death among patients treated at a comprehensive cancer center. J Palliat Med (2005) 1.67