PubRank

A Dierich

Author PubWeight™ 142.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 2000 8.34
2 Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 1996 7.15
3 Mice lacking MHC class II molecules. Cell 1991 6.25
4 Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science 1996 5.55
5 Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci U S A 1997 5.24
6 Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes. Development 2000 5.03
7 Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression. Cell 1991 3.53
8 Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice. Nat Genet 1996 3.42
9 Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses. Nat Genet 2000 3.10
10 Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants. Development 1994 2.98
11 The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron 1998 2.87
12 Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid. EMBO J 1991 2.84
13 Function of retinoic acid receptor gamma in the mouse. Cell 1993 2.83
14 Distinct functions of the two isoforms of dopamine D2 receptors. Nature 2000 2.83
15 Mice lacking all conventional MHC class II genes. Proc Natl Acad Sci U S A 1999 2.83
16 High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice. Proc Natl Acad Sci U S A 1993 2.78
17 Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice. Nature 1996 2.74
18 Mice lacking TdT: mature animals with an immature lymphocyte repertoire. Science 1993 2.42
19 Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors. Nature 1995 2.37
20 Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice. J Clin Invest 1999 2.34
21 Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway. Cell 1996 2.32
22 Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science 1994 2.32
23 Mice lacking the MHC class II-associated invariant chain. Cell 1993 2.30
24 Abnormal spermatogenesis in RXR beta mutant mice. Genes Dev 1996 2.17
25 Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the Period1 gene. EMBO J 2001 2.11
26 Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell 1993 2.09
27 Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development. Development 2000 2.09
28 Nuclear targeting defect of SMN lacking the C-terminus in a mouse model of spinal muscular atrophy. Hum Mol Genet 2000 2.09
29 A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene. Cell 1993 2.08
30 Promoter elements of genes coding for proteins and modulation of transcription by estrogens and progesterone. Recent Prog Horm Res 1984 2.04
31 Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning. Development 1996 1.99
32 In vivo functional analysis of the Hoxa-1 3' retinoic acid response element (3'RARE). Development 1997 1.95
33 In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy. J Cell Biol 1998 1.95
34 Late arrest of spermiogenesis and germ cell apoptosis in mice lacking the TBP-like TLF/TRF2 gene. Mol Cell 2001 1.94
35 Cellular retinol-binding protein I is essential for vitamin A homeostasis. EMBO J 1999 1.90
36 Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter. EMBO J 1988 1.78
37 Serotonin 2B receptor is required for heart development. Proc Natl Acad Sci U S A 2000 1.75
38 Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation. Hum Mol Genet 2000 1.66
39 Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal. EMBO J 1998 1.59
40 RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable. Proc Natl Acad Sci U S A 1996 1.52
41 Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification. Development 1998 1.51
42 The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development. Development 1998 1.47
43 Role of the retinoic acid receptor beta (RARbeta) during mouse development. Int J Dev Biol 1997 1.41
44 Independent modes of natural killing distinguished in mice lacking Lag3. Science 1996 1.26
45 The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein. J Biol Chem 2000 1.23
46 Active multilayered capsules for in vivo bone formation. Proc Natl Acad Sci U S A 2010 1.11
47 Retinoic acid receptor beta 2 (RAR beta 2) null mutant mice appear normal. Dev Biol 1994 1.10
48 Developmental roles of the retinoic acid receptors. J Steroid Biochem Mol Biol 1995 1.08
49 The net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shock. Mol Cell Biol 1999 1.06
50 The chicken ovalbumin promoter is under negative control which is relieved by steroid hormones. EMBO J 1987 1.06
51 The cellular retinoic acid binding protein I is dispensable. Proc Natl Acad Sci U S A 1994 1.05
52 Knockout mice as model systems for studying nm23/NDP kinase gene functions. Application to the nm23-M1 gene. J Bioenerg Biomembr 2003 1.01
53 Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells. Cell Death Differ 2006 1.00
54 Cryptorchidism and homeotic transformations of spinal nerves and vertebrae in Hoxa-10 mutant mice. Proc Natl Acad Sci U S A 1995 1.00
55 The ribosomal S6 kinases, cAMP-responsive element-binding, and STAT3 proteins are regulated by different leukemia inhibitory factor signaling pathways in mouse embryonic stem cells. J Biol Chem 2001 0.99
56 Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain. Development 1999 0.97
57 LAG-3 is not responsible for selecting T helper cells in CD4-deficient mice. Int Immunol 1996 0.90
58 Visualization of CD4/CD8 T cell commitment. J Exp Med 1998 0.87
59 Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart. Dev Biol 1998 0.86
60 Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms. Mech Dev 1997 0.84
61 CD44 in differentiated embryonic stem cells: surface expression and transcripts encoding multiple variants. Dev Immunol 1994 0.82
62 Roles of Hox genes: what we have learnt from gain of function and loss of function mutations in the mouse. C R Acad Sci III 1993 0.80
63 Comparative investigation of free nucleotides in two neuroblastoma clonal cell lines. J Neurochem 1976 0.79
64 Retinoid receptors and binding proteins. J Cell Sci Suppl 1992 0.79
65 Behavioral characterization of mice packing the 5-HT1B receptor. NIDA Res Monogr 1996 0.78
66 Purification and characterization of a nicotinamide deamidase released into the growth medium of neuroblastoma in vitro. Biochim Biophys Acta 1980 0.77
67 Nicotinamide deamidase released by neuroblastoma cell cultures. J Neurochem 1979 0.77
68 Investigations on myelination in vitro. III. Ultrastructural, biochemical, and immunohistochemical studies in cultures of dissociated brain cells from embryonic mice. J Neurosci Res 1981 0.75
69 Free nucleotides in bromodeoxyuridine-treated neuroblastoma cells. Neurochem Res 1976 0.75
70 [Free nucleotides of nerve cells, in culture]. C R Seances Acad Sci D 1980 0.75
71 Effect of pentobarbital on mitochondrial synthesis in cultured glial cells. J Neurochem 1979 0.75
72 In vitro protein synthesis activity of poly(A) RNA from neuroblastoma cells. Neurochem Res 1980 0.75
73 RNA metabolism in M1 adrenergic neuroblastoma cells. Biochimie 1978 0.75
74 DNA of bromodeoxyuridine-treated neuroblastoma cells. J Neurochem 1978 0.75
75 Fingerprint studies on mitochondrial and cytoplasmic rRNAs of mouse liver. Biochimie 1975 0.75
76 Hybridization studies of poly A-RNA from 5'-bromodeoxyuridine treated neuroblastoma cells. Biochimie 1980 0.75
77 The conalbumin "TATA" box sequence and the SV40 72 base-pair repeat region influence expression of a chimeric gene in vivo. Prog Clin Biol Res 1982 0.75
78 Hybridization of mitochondrial and cytoplasmic ribosomal RNA with mitochondrial and nuclear DNA. Experientia 1975 0.75
79 [Nicotinamide desamidase in the culture medium of neuroblastoma cells]. C R Acad Sci Hebd Seances Acad Sci D 1978 0.75
80 Brain nucleic acids and protein in various neurological mutant mice. Neurochem Res 1980 0.75
81 Biosynthesis pathways of nucleotides in different nerve cell cultures. J Neurochem 1980 0.75