Published in Proc Natl Acad Sci U S A on February 16, 2010
Strategies for controlled delivery of growth factors and cells for bone regeneration. Adv Drug Deliv Rev (2012) 1.57
Tissue integration of growth factor-eluting layer-by-layer polyelectrolyte multilayer coated implants. Biomaterials (2010) 1.24
Controlling in vivo stability and biodistribution in electrostatically assembled nanoparticles for systemic delivery. Nano Lett (2011) 1.24
Tunable dual growth factor delivery from polyelectrolyte multilayer films. Biomaterials (2011) 1.23
Surface-mediated bone tissue morphogenesis from tunable nanolayered implant coatings. Sci Transl Med (2013) 1.05
Characterization of tunable FGF-2 releasing polyelectrolyte multilayers. Biomacromolecules (2010) 1.01
Osteophilic multilayer coatings for accelerated bone tissue growth. Adv Mater (2012) 0.98
The architecture and biological performance of drug-loaded LbL nanoparticles. Biomaterials (2013) 0.96
Adaptive growth factor delivery from a polyelectrolyte coating promotes synergistic bone tissue repair and reconstruction. Proc Natl Acad Sci U S A (2014) 0.88
Polymer multilayers loaded with antifungal β-peptides kill planktonic Candida albicans and reduce formation of fungal biofilms on the surfaces of flexible catheter tubes. J Control Release (2014) 0.85
Capillary flow layer-by-layer: a microfluidic platform for the high-throughput assembly and screening of nanolayered film libraries. ACS Nano (2014) 0.81
Ordered and kinetically discrete sequential protein release from biodegradable thin films. Angew Chem Int Ed Engl (2014) 0.81
A living thick nanofibrous implant bifunctionalized with active growth factor and stem cells for bone regeneration. Int J Nanomedicine (2015) 0.77
Synergistic Effects of Vascular Endothelial Growth Factor on Bone Morphogenetic Proteins Induced Bone Formation In Vivo: Influencing Factors and Future Research Directions. Biomed Res Int (2016) 0.75
Biodegradable chitosan nanoparticle coatings on titanium for the delivery of BMP-2. Biomolecules (2015) 0.75
Nanoengineered implant as a new platform for regenerative nanomedicine using 3D well-organized human cell spheroids. Int J Nanomedicine (2017) 0.75
Biomimetic calcium phosphate/polyelectrolyte multilayer coatings for sequential delivery of multiple biological factors. J Biomed Mater Res A (2017) 0.75
Fabrication and clinical application of easy-to-operate pre-cured CPC/rhBMP-2 micro-scaffolds for bone regeneration. Am J Transl Res (2016) 0.75
The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J Embryol Exp Morphol (1985) 12.74
Novel regulators of bone formation: molecular clones and activities. Science (1988) 10.74
Embryonic stem cell-derived glial precursors: a source of myelinating transplants. Science (1999) 5.13
Transforming growth factor-beta: biological function and chemical structure. Science (1986) 5.08
Long-term proliferation of mouse primordial germ cells in culture. Nature (1992) 4.31
Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro. Mech Dev (1996) 3.45
Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily. Science (1992) 3.36
Nanoengineering of inorganic and hybrid hollow spheres by colloidal templating Science (1998) 3.28
Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers. Differentiation (1991) 2.97
Differentiation of embryonic stem cells into adipocytes in vitro. J Cell Sci (1997) 2.33
Differentiation of osteoblasts and in vitro bone formation from murine embryonic stem cells. Tissue Eng (2001) 1.97
Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery). J Tissue Eng Regen Med (2008) 1.77
Endochondral bone tissue engineering using embryonic stem cells. Proc Natl Acad Sci U S A (2008) 1.70
In vitro differentiation of embryonic stem cells into mineralized osteoblasts. Differentiation (2003) 1.65
Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. J Cell Biochem (1997) 1.61
Multiple and time-scheduled in situ DNA delivery mediated by beta-cyclodextrin embedded in a polyelectrolyte multilayer. Proc Natl Acad Sci U S A (2006) 1.55
Bone morphogenetic proteins in tissue engineering: the road from the laboratory to the clinic, part I (basic concepts). J Tissue Eng Regen Med (2008) 1.54
Delivery systems for BMPs: factors contributing to protein retention at an application site. J Bone Joint Surg Am (2001) 1.27
From stem cells to beta cells: new strategies in cell therapy of diabetes mellitus. Diabetologia (2001) 1.20
Compactin enhances osteogenesis in murine embryonic stem cells. Biochem Biophys Res Commun (2001) 1.20
Stimulation of chondrogenesis in limb bud mesoderm cells by recombinant human bone morphogenetic protein 2B (BMP-2B) and modulation by transforming growth factor beta 1 and beta 2. Exp Cell Res (1991) 1.19
Differentiation plasticity of chondrocytes derived from mouse embryonic stem cells. J Cell Sci (2002) 1.10
Implantation of recombinant human bone morphogenetic proteins with biomaterial carriers: A correlation between protein pharmacokinetics and osteoinduction in the rat ectopic model. J Biomed Mater Res (2000) 1.05
Survival and function of mouse embryonic stem cell-derived cardiomyocytes in ectopic transplants. Cardiovasc Res (2003) 0.97
Degradable polyelectrolyte capsules filled with oligonucleotide sequences. Angew Chem Int Ed Engl (2006) 0.90
Engineering virus functionalities on colloidal polyelectrolyte lipid composites. Angew Chem Int Ed Engl (2005) 0.83
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A (2000) 8.34
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature (1996) 7.15
Mice lacking MHC class II molecules. Cell (1991) 6.25
Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science (1996) 5.55
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci U S A (1997) 5.24
Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes. Development (2000) 5.03
Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression. Cell (1991) 3.53
Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice. Nat Genet (1996) 3.42
Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses. Nat Genet (2000) 3.10
Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants. Development (1994) 2.98
The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron (1998) 2.87
Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid. EMBO J (1991) 2.84
Function of retinoic acid receptor gamma in the mouse. Cell (1993) 2.83
Distinct functions of the two isoforms of dopamine D2 receptors. Nature (2000) 2.83
Mice lacking all conventional MHC class II genes. Proc Natl Acad Sci U S A (1999) 2.83
High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice. Proc Natl Acad Sci U S A (1993) 2.78
Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice. Nature (1996) 2.74
Mice lacking TdT: mature animals with an immature lymphocyte repertoire. Science (1993) 2.42
Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors. Nature (1995) 2.37
Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice. J Clin Invest (1999) 2.34
Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway. Cell (1996) 2.32
Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science (1994) 2.32
Mice lacking the MHC class II-associated invariant chain. Cell (1993) 2.30
Abnormal spermatogenesis in RXR beta mutant mice. Genes Dev (1996) 2.17
Lipid-based nanotherapeutics for siRNA delivery. J Intern Med (2010) 2.15
Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the Period1 gene. EMBO J (2001) 2.11
Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell (1993) 2.09
Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development. Development (2000) 2.09
Nuclear targeting defect of SMN lacking the C-terminus in a mouse model of spinal muscular atrophy. Hum Mol Genet (2000) 2.09
A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene. Cell (1993) 2.08
Quantum measurement and orientation tracking of fluorescent nanodiamonds inside living cells. Nat Nanotechnol (2011) 2.05
Promoter elements of genes coding for proteins and modulation of transcription by estrogens and progesterone. Recent Prog Horm Res (1984) 2.04
Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning. Development (1996) 1.99
In vivo functional analysis of the Hoxa-1 3' retinoic acid response element (3'RARE). Development (1997) 1.95
In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy. J Cell Biol (1998) 1.95
Late arrest of spermiogenesis and germ cell apoptosis in mice lacking the TBP-like TLF/TRF2 gene. Mol Cell (2001) 1.94
Cellular retinol-binding protein I is essential for vitamin A homeostasis. EMBO J (1999) 1.90
Molecular basis for the explanation of the exponential growth of polyelectrolyte multilayers. Proc Natl Acad Sci U S A (2002) 1.80
Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter. EMBO J (1988) 1.78
Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production. Osteoarthritis Cartilage (2006) 1.77
Serotonin 2B receptor is required for heart development. Proc Natl Acad Sci U S A (2000) 1.75
Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation. Hum Mol Genet (2000) 1.66
Obesity and osteoarthritis: more complex than predicted! Ann Rheum Dis (2006) 1.59
Multiple and time-scheduled in situ DNA delivery mediated by beta-cyclodextrin embedded in a polyelectrolyte multilayer. Proc Natl Acad Sci U S A (2006) 1.55
RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable. Proc Natl Acad Sci U S A (1996) 1.52
Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification. Development (1998) 1.51
The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development. Development (1998) 1.47
Role of the retinoic acid receptor beta (RARbeta) during mouse development. Int J Dev Biol (1997) 1.41
Stereoselective distribution of tiaprofenic acid in synovium and cartilage in osteoarthritic patients. Eur J Clin Pharmacol (1996) 1.40
Independent modes of natural killing distinguished in mice lacking Lag3. Science (1996) 1.26
The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein. J Biol Chem (2000) 1.23
Evaluation of the effect of three surface treatments on the biocompatibility of 316L stainless steel using human differentiated cells. Biomaterials (1996) 1.23
Dipping versus spraying: exploring the deposition conditions for speeding up layer-by-layer assembly. Langmuir (2005) 1.19
Spontaneous phase transfer of nanoparticulate metals from organic to aqueous media. Angew Chem Int Ed Engl (2001) 1.16
Influence of the polyelectrolyte molecular weight on exponentially growing multilayer films in the linear regime. Langmuir (2007) 1.13
Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage. Hum Reprod (2004) 1.13
Retinoic acid receptor beta 2 (RAR beta 2) null mutant mice appear normal. Dev Biol (1994) 1.10
Developmental roles of the retinoic acid receptors. J Steroid Biochem Mol Biol (1995) 1.08
Decomposable hollow biopolymer-based capsules. Biomacromolecules (2001) 1.07
The chicken ovalbumin promoter is under negative control which is relieved by steroid hormones. EMBO J (1987) 1.06
The net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shock. Mol Cell Biol (1999) 1.06
The cellular retinoic acid binding protein I is dispensable. Proc Natl Acad Sci U S A (1994) 1.05
"K-region" oxides and related oxidized metabolites of carcinogenic aromatic hydrocarbons. J Am Chem Soc (1975) 1.05
Static friction on the fly: velocity depinning transitions of lubricants in motion. Phys Rev Lett (2007) 1.04
RXRalpha overexpression in cardiomyocytes causes dilated cardiomyopathy but fails to rescue myocardial hypoplasia in RXRalpha-null fetuses. J Clin Invest (2000) 1.02
Knockout mice as model systems for studying nm23/NDP kinase gene functions. Application to the nm23-M1 gene. J Bioenerg Biomembr (2003) 1.01
Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells. Cell Death Differ (2006) 1.00
Cryptorchidism and homeotic transformations of spinal nerves and vertebrae in Hoxa-10 mutant mice. Proc Natl Acad Sci U S A (1995) 1.00
Biocolloids with ordered urease multilayer shells as enzymatic reactors. Anal Chem (2001) 0.99
New synthetic approaches to polycyclic aromatic hydrocarbons and their carcinogenic oxidized metabolites: derivatives of benzo[s]picene, benzo[rst]pentaphene, and dibenzo[b,def]chrysene. J Org Chem (2000) 0.99
The ribosomal S6 kinases, cAMP-responsive element-binding, and STAT3 proteins are regulated by different leukemia inhibitory factor signaling pathways in mouse embryonic stem cells. J Biol Chem (2001) 0.99
Sperm count and chromatin structure in men exposed to inorganic lead: lowest adverse effect levels. Occup Environ Med (2002) 0.98
Cell interactions with polyelectrolyte multilayer films. Biomacromolecules (2002) 0.98
Tuberculosis of the patella. Arch Orthop Trauma Surg (2003) 0.97
Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain. Development (1999) 0.97
Sodium alginate sponges with or without sodium hyaluronate: in vitro engineering of cartilage. J Biomed Mater Res (2001) 0.97
Polyelectrolyte multilayer films with pegylated polypeptides as a new type of anti-microbial protection for biomaterials. Biomaterials (2004) 0.95
Cytocompatibility of Ti-6Al-4V and Ti-5Al-2.5Fe alloys according to three surface treatments, using human fibroblasts and osteoblasts. Biomaterials (1996) 0.95
Magnetic resonance imaging may be an asset to diagnose and classify fluoroquinolone-associated Achilles tendinitis. Fundam Clin Pharmacol (1995) 0.93
Role of monocytes in mediating HIV-specific antibody-dependent cellular cytotoxicity. J Immunol Methods (2012) 0.92
Do clinical presentation and pre-operative quality of life predict satisfaction with care after total hip or knee replacement? J Bone Joint Surg Br (2006) 0.91
Secondary structure of proteins adsorbed onto or embedded in polyelectrolyte multilayers. Biomacromolecules (2002) 0.91
Beta-tricalcium phosphate ceramic as a bone substitute in orthopaedic surgery. Int Orthop (2002) 0.90
LAG-3 is not responsible for selecting T helper cells in CD4-deficient mice. Int Immunol (1996) 0.90
Review: Magnetic resonance imaging of normal and osteoarthritic cartilage. Arthritis Rheum (1998) 0.89
The structure of the cartilaginous end-plates in elder people. Surg Radiol Anat (2000) 0.88
15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways. FEBS Lett (2001) 0.88
Acute haematogenous osteomyelitis of the patella revealed by a pathological fracture in multiple myeloma. J Intern Med (1992) 0.88
Modified shoelace technique for delayed primary closure of the thigh after acute compartment syndrome. Acta Orthop Belg (2002) 0.88
Moderate-impact exercise is associated with decreased severity of experimental osteoarthritis in rats. Rheumatology (Oxford) (2003) 0.88
Visualization of CD4/CD8 T cell commitment. J Exp Med (1998) 0.87
Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart. Dev Biol (1998) 0.86
Electromagnetic interference of digital and analog cellular telephones with implantable cardioverter defibrillators: in vitro and in vivo studies. Pacing Clin Electrophysiol (1999) 0.86
Polydactyly of the foot. Literature review and case presentations. Acta Orthop Belg (2002) 0.86
Mastectomy with primary reconstruction. Lancet (1980) 0.85
Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms. Mech Dev (1997) 0.84
In vitro effects of diacerein on NO production by chondrocytes in response to proinflammatory mediators. Biomed Mater Eng (2008) 0.83
[Cartilage tissue engineering: state-of-the-art and future approaches]. Pathol Biol (Paris) (2005) 0.83
Cartilage repair using new polysaccharidic biomaterials: macroscopic, histological and biochemical approaches in a rat model of cartilage defect. Osteoarthritis Cartilage (2003) 0.83