Published in J Biol Chem on February 05, 1991
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Demonstration of a [K+,Cl-]-cotransport system in human red cells by its sensitivity to [(dihydroindenyl)oxy]alkanoic acids: regulation of cell swelling and distinction from the bumetanide-sensitive [Na+,K+,Cl-]-cotransport system. Mol Pharmacol (1988) 1.43
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Endothelin-induced contraction of human peripheral resistance vessels is partly dependent on stimulation of sodium-hydrogen exchange. J Hypertens (1989) 1.41
Intracellular pH regulation in resting and contracting segments of rat mesenteric resistance vessels. J Physiol (1988) 1.39
Inhibition of Na+/Ca2+ exchange in membrane vesicle and papillary muscle preparations from guinea pig heart by analogs of amiloride. Proc Natl Acad Sci U S A (1984) 1.39
Inhibition of na/h antiport activity in sugar beet tonoplast by analogs of amiloride. Plant Physiol (1987) 1.36
Evidence that Na+/H+ exchange regulates receptor-mediated phospholipase A2 activation in human platelets. J Biol Chem (1986) 1.34
Regulation of human neutrophil chemotaxis by intracellular pH. J Biol Chem (1986) 1.34
Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types. Biochem Biophys Res Commun (1983) 1.32
Sodium and chloride transport across rabbit ileal brush border. I. Evidence for Na-H exchange. Am J Physiol (1983) 1.31
Role of NHE3 in mediating renal brush border Na+-H+ exchange. Adaptation to metabolic acidosis. J Biol Chem (1996) 1.30
Membrane distribution of sodium-hydrogen and chloride-bicarbonate exchangers in crypt and villus cell membranes from rabbit ileum. J Clin Invest (1988) 1.30
Structure-activity relationships of amiloride and certain of its analogues in relation to the blockade of the Na+/H+ exchange system. Mol Pharmacol (1984) 1.28
Purification and reconstitution of chloride channels from kidney and trachea. Science (1989) 1.25
Regulation of intracellular pH in human platelets. Effects of thrombin, A23187, and ionomycin and evidence for activation of Na+/H+ exchange and its inhibition by amiloride analogs. J Biol Chem (1986) 1.24
pH regulation in spread cells and round cells. J Biol Chem (1990) 1.22
Specific association of megalin and the Na+/H+ exchanger isoform NHE3 in the proximal tubule. J Biol Chem (1999) 1.22
Inhibition of Na+/Ca2+ exchange in pituitary plasma membrane vesicles by analogues of amiloride. Biochemistry (1985) 1.20
Chloride/formate exchange with formic acid recycling: a mechanism of active chloride transport across epithelial membranes. Proc Natl Acad Sci U S A (1985) 1.20
Role of protein kinase C and the Na+/H+ antiporter in suppression of apoptosis by granulocyte macrophage colony-stimulating factor and interleukin-3. J Biol Chem (1992) 1.19
Characterization of potent Na+/H+ exchange inhibitors from the amiloride series in A431 cells. Biochemistry (1984) 1.19
Ontogeny of rabbit renal cortical NHE3 and NHE1: effect of glucocorticoids. Am J Physiol (1995) 1.18
Inhibition of chemotactic factor-activated Na+/H+ exchange in human neutrophils by analogues of amiloride: structure-activity relationships in the amiloride series. Mol Pharmacol (1986) 1.18
Epithelial chloride channel. Development of inhibitory ligands. J Gen Physiol (1987) 1.17
Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney. Am J Physiol (1992) 1.16
Biosynthesis of the gp330/44-kDa Heymann nephritis antigenic complex: assembly takes place in the ER. Am J Physiol (1993) 1.16
Amiloride, a specific inhibitor for the Na+-driven flagellar motors of alkalophilic Bacillus. J Biol Chem (1988) 1.15
Specificity and modes of the anion exchanger in dog renal microvillus membranes. Am J Physiol (1983) 1.14
Inhibitors of Na+/H+ exchange block stimulus-provoked arachidonic acid release in human platelets. Selective effects on platelet activation by epinephrine, ADP, and lower concentrations of thrombin. J Biol Chem (1985) 1.13
Regulation of intracellular pH in cultured hippocampal neurons by an amiloride-insensitive Na+/H+ exchanger. J Biol Chem (1991) 1.13
Thrombin activation of the Na+/H+ exchanger in vascular smooth muscle cells. Evidence for a kinase C-independent pathway which is Ca2+-dependent and pertussis toxin-sensitive. J Biol Chem (1987) 1.12
Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family. J Biol Chem (1995) 1.12
Specific inhibition of the Na(+)-driven flagellar motors of alkalophilic Bacillus strains by the amiloride analog phenamil. J Bacteriol (1990) 1.12
The pH of spontaneously beating cultured rat heart cells is regulated by an ATP-calmodulin-dependent Na+/H+ antiport. Circ Res (1989) 1.11
Photolabeling of tonoplast from sugar beet cell suspensions by [h]5-(N-methyl-N-isobutyl)-amiloride, an inhibitor of the vacuolar na/h antiport. Plant Physiol (1990) 1.11
Rescue from programmed cell death in leukemic and normal myeloid cells. Blood (1991) 1.10
pH gradient-stimulated transport of urate and p-aminohippurate in dog renal microvillus membrane vesicles. J Clin Invest (1980) 1.09
Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger. Biochimie (1988) 1.09
Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange. J Biol Chem (1985) 1.09
Effects of extracellular ATP on ion transport systems and [Ca2+]i in rat parotid acinar cells. Comparison with the muscarinic agonist carbachol. J Gen Physiol (1990) 1.08
Assembly of distinctive coated pit and microvillar microdomains in the renal brush border. Am J Physiol (1992) 1.08
Therapeutic potential of analogues of amiloride: inhibition of the regulation of intracellular pH as a possible mechanism of tumour selective therapy. Br J Cancer (1993) 1.07
Inhibitors of Na+/H+ exchange block epinephrine- and ADP-induced stimulation of human platelet phospholipase C by blockade of arachidonic acid release at a prior step. J Biol Chem (1986) 1.07
Association of Na(+)-H(+) exchanger isoform NHE3 and dipeptidyl peptidase IV in the renal proximal tubule. J Biol Chem (2001) 1.06
Estimation of the number and turnover rate of Na+/H+ exchangers in lymphocytes. Effect of phorbol ester and osmotic shrinking. J Biol Chem (1987) 1.05
Cl- transport via anion exchange in Necturus renal microvillus membranes. Am J Physiol (1984) 1.05
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Evidence for a halide-binding site in halorhodopsin. J Biol Chem (1983) 1.04
Hydrogen ion cotransport by the renal brush border glutamate transporter. Biochemistry (1983) 1.04
Chemical modification of cell proliferation and fluid secretion in renal cysts. Kidney Int (1989) 1.03
Properties and physiologic roles of the plasma membrane sodium-hydrogen exchanger. J Clin Invest (1986) 1.03
NMR measurements of Na+ and cellular energy in ischemic rat heart: role of Na(+)-H+ exchange. Am J Physiol (1993) 1.03
Blastocoel expansion in the preimplantation mouse embryo: role of extracellular sodium and chloride and possible apical routes of their entry. Dev Biol (1989) 1.02
Glucocorticoid stimulation of ileal Na+ absorptive cell brush border Na+/H+ exchange and association with an increase in message for NHE-3, an epithelial Na+/H+ exchanger isoform. J Biol Chem (1993) 1.02
Characterization of Na+-linked and Na+-independent Cl-/HCO3- exchange systems in Chinese hamster lung fibroblasts. J Biol Chem (1988) 1.02
Ksp-cadherin gene promoter. I. Characterization and renal epithelial cell-specific activity. Am J Physiol (1999) 1.01
Active (9.6 s) and inactive (21 s) oligomers of NHE3 in microdomains of the renal brush border. J Biol Chem (2000) 1.01
Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways. J Biol Chem (1990) 1.01
Relations among sodium pump inhibition, Na-Ca and Na-H exchange activities, and Ca-H interaction in cultured chick heart cells. Circ Res (1987) 1.01
Ionic mechanism of Na+-HCO3- cotransport in rabbit renal basolateral membrane vesicles. J Biol Chem (1989) 1.01
Determination of the coupling ratio for Na+ -H+ exchange in renal microvillus membrane vesicles. Biochim Biophys Acta (1982) 1.01
A role for Na+/Ca2+ exchange in the generation of superoxide radicals by human neutrophils. J Biol Chem (1990) 1.01
Microtubule integrity is necessary for the epithelial barrier function of cultured thyroid cell monolayers. Exp Cell Res (1995) 1.00
Successive inactivation of the force-generating units of sodium-driven bacterial flagellar motors by a photoreactive amiloride analog. J Biol Chem (1994) 1.00
Activation of the Na+/H+ and Cl-/HCO3- exchange by stimulation of acid secretion in the parietal cell. J Biol Chem (1988) 1.00
Bicarbonate determines cytoplasmic pH and suppresses mitogen-induced alkalinization in fibroblastic cells. J Biol Chem (1988) 1.00
Anion exchange pathways for Cl- transport in rabbit renal microvillus membranes. Am J Physiol (1987) 1.00
Activation of sodium-proton exchange is not a prerequisite for Ca2+ mobilization and aggregation in human platelets. FEBS Lett (1987) 0.99
Na+-Ca2+ exchange in human neutrophils. Am J Physiol (1988) 0.99
Immunocytochemical and functional characterization of Na+ conductance in adult alveolar pneumocytes. Am J Physiol (1992) 0.99
Na+-H+ exchanger of human placental brush-border membrane: identification and characterization. Am J Physiol (1986) 0.98
Na+/H+ exchanger activity in the pig kidney epithelial cell line, LLC-PK1: inhibition by amiloride and its derivatives. Biochem Biophys Res Commun (1985) 0.98
Immunolocalization of Ksp-cadherin in the adult and developing rabbit kidney. Am J Physiol (1999) 0.98
Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange. Proc Natl Acad Sci U S A (1984) 0.98
The control of mediator release from RBL-2H3 cells: roles for Ca2+, Na+, and protein kinase C1. J Immunol (1987) 0.98
Effects of muscarinic, alpha-adrenergic, and substance P agonists and ionomycin on ion transport mechanisms in the rat parotid acinar cell. The dependence of ion transport on intracellular calcium. J Gen Physiol (1989) 0.98