Resurrection of DNA function in vivo from an extinct genome.

PubWeight™: 0.93‹?›

🔗 View Article (PMC 2375112)

Published in PLoS One on May 21, 2008

Authors

Andrew J Pask1, Richard R Behringer, Marilyn B Renfree

Author Affiliations

1: Department of Molecular Genetics, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America.

Articles cited by this

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09

Evolution at two levels in humans and chimpanzees. Science (1975) 21.07

The delayed rise of present-day mammals. Nature (2007) 15.98

The locus of evolution: evo devo and the genetics of adaptation. Evolution (2007) 6.24

Analysis of one million base pairs of Neanderthal DNA. Nature (2006) 6.17

SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol Cell Biol (1997) 5.72

Ancient DNA: extraction, characterization, molecular cloning, and enzymatic amplification. Proc Natl Acad Sci U S A (1989) 5.50

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J (1998) 5.15

Ancient DNA. Proc Biol Sci (2005) 4.84

Cretaceous eutherians and Laurasian origin for placental mammals near the K/T boundary. Nature (2007) 4.30

An Early Cretaceous tribosphenic mammal and metatherian evolution. Science (2003) 4.07

Homeotic genes and the evolution of arthropods and chordates. Nature (1995) 3.96

Emerging principles of regulatory evolution. Proc Natl Acad Sci U S A (2007) 3.42

The regulation of myogenin gene expression during the embryonic development of the mouse. Genes Dev (1993) 3.15

A melanocortin 1 receptor allele suggests varying pigmentation among Neanderthals. Science (2007) 2.15

A 182 bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice. J Cell Sci (1995) 1.90

The current biodiversity extinction event: scenarios for mitigation and recovery. Proc Natl Acad Sci U S A (2001) 1.81

Nuclear gene indicates coat-color polymorphism in mammoths. Science (2006) 1.77

An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes. Mol Cell Biol (1996) 1.64

Different cis-regulatory DNA elements mediate developmental stage- and tissue-specific expression of the human COL2A1 gene in transgenic mice. J Cell Biol (1998) 0.94

Evolution of protein expression: new genes for a new diet. Curr Biol (2007) 0.86

Articles by these authors

(truncated to the top 100)

The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell (2002) 15.20

Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A (2003) 7.87

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet (2010) 6.81

Genome analysis of the platypus reveals unique signatures of evolution. Nature (2008) 5.74

Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev (2004) 4.78

Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. Proc Natl Acad Sci U S A (2005) 4.25

Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell (2006) 4.13

Functional analysis of Sox8 and Sox9 during sex determination in the mouse. Development (2004) 3.25

Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3. Proc Natl Acad Sci U S A (2002) 2.99

Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development. Development (2005) 2.98

Functional genetic analysis of mouse chromosome 11. Nature (2003) 2.87

Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Proc Natl Acad Sci U S A (2005) 2.82

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination. PLoS Biol (2006) 2.75

Requirement of Bmpr1a for Müllerian duct regression during male sexual development. Nat Genet (2002) 2.75

Generation of Bmpr/Alk3 conditional knockout mice. Genesis (2002) 2.71

Distinct functions for Bmp signaling in lip and palate fusion in mice. Development (2005) 2.46

The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours. Nature (2005) 2.29

Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks. Dev Cell (2002) 2.24

Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians. Nat Genet (2008) 2.20

Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo. Nature (2004) 2.16

Cord blood stem cell therapy for acquired immune deficiency syndrome. Stem Cells Dev (2010) 2.06

The evolution of the DLK1-DIO3 imprinted domain in mammals. PLoS Biol (2008) 2.05

Ovca1 regulates cell proliferation, embryonic development, and tumorigenesis. Genes Dev (2004) 2.04

Regulatory divergence modifies limb length between mammals. Genes Dev (2008) 1.96

Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells. Ann N Y Acad Sci (2004) 1.80

Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function. Mol Endocrinol (2004) 1.79

Developmental genetics of the female reproductive tract in mammals. Nat Rev Genet (2003) 1.78

Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa. Proc Natl Acad Sci U S A (2004) 1.77

Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation. Development (2003) 1.73

Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Mol Cell Biol (2007) 1.72

Retracted Regulation of NF-kappaB circuitry by a component of the nucleosome remodeling and deacetylase complex controls inflammatory response homeostasis. J Biol Chem (2010) 1.71

Retrotransposon silencing by DNA methylation can drive mammalian genomic imprinting. PLoS Genet (2007) 1.70

Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development. J Comp Neurol (2008) 1.65

Granulosa cell-specific inactivation of follistatin causes female fertility defects. Mol Endocrinol (2003) 1.62

Bone morphogenetic protein type IA receptor signaling regulates postnatal osteoblast function and bone remodeling. J Biol Chem (2004) 1.62

β-Catenin is essential for Müllerian duct regression during male sexual differentiation. Development (2011) 1.62

Wt1 negatively regulates beta-catenin signaling during testis development. Development (2008) 1.61

BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development (2006) 1.59

Developmental potential and behavior of tetraploid cells in the mouse embryo. Dev Biol (2005) 1.56

Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev (2003) 1.55

Uterine epithelial estrogen receptor α is dispensable for proliferation but essential for complete biological and biochemical responses. Proc Natl Acad Sci U S A (2010) 1.54

Impaired angiogenesis in aminopeptidase N-null mice. Proc Natl Acad Sci U S A (2007) 1.53

Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev (2006) 1.52

Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma. Arthritis Rheum (2007) 1.51

Misregulated Wnt/beta-catenin signaling leads to ovarian granulosa cell tumor development. Cancer Res (2005) 1.51

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. Proc Natl Acad Sci U S A (2006) 1.51

Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus. Circ Res (2005) 1.48

Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo. Dev Biol (2002) 1.47

Sox9-expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons. Genesis (2010) 1.46

Generation of viable male and female mice from two fathers. Biol Reprod (2010) 1.46

Development of bat flight: morphologic and molecular evolution of bat wing digits. Proc Natl Acad Sci U S A (2006) 1.45

Evolution of vertebrate interferon inducible transmembrane proteins. BMC Genomics (2012) 1.44

Bmp4 in limb bud mesoderm regulates digit pattern by controlling AER development. Dev Biol (2004) 1.41

A mesenchymal perspective of Müllerian duct differentiation and regression in Amhr2-lacZ mice. Mol Reprod Dev (2008) 1.41

LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proc Natl Acad Sci U S A (2007) 1.41

Dicer is required for female reproductive tract development and fertility in the mouse. Mol Reprod Dev (2009) 1.40

Deletion of the orphan nuclear receptor COUP-TFII in uterus leads to placental deficiency. Proc Natl Acad Sci U S A (2007) 1.38

Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification. Proc Natl Acad Sci U S A (2006) 1.37

Cellular mechanisms of Müllerian duct formation in the mouse. Dev Biol (2007) 1.36

Lim1 is essential for the correct laminar positioning of retinal horizontal cells. J Neurosci (2007) 1.35

A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice. Development (2002) 1.35

Transition nuclear proteins are required for normal chromatin condensation and functional sperm development. Genesis (2004) 1.32

Generation of aggrecan-CreERT2 knockin mice for inducible Cre activity in adult cartilage. Genesis (2009) 1.31

Requirement of Lim1 for female reproductive tract development. Development (2003) 1.29

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25. Nat Commun (2011) 1.27

Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression. Carcinogenesis (2008) 1.26

Regulation of retinal cone bipolar cell differentiation and photopic vision by the CVC homeobox gene Vsx1. Curr Biol (2004) 1.26

Embryonic staging system for the short-tailed fruit bat, Carollia perspicillata, a model organism for the mammalian order Chiroptera, based upon timed pregnancies in captive-bred animals. Dev Dyn (2005) 1.26

Cthrc1 is a positive regulator of osteoblastic bone formation. PLoS One (2008) 1.24

5alpha-androstane-3alpha,17beta-diol is formed in tammar wallaby pouch young testes by a pathway involving 5alpha-pregnane-3alpha,17alpha-diol-20-one as a key intermediate. Endocrinology (2003) 1.24

Genomic imprinting of IGF2, p57(KIP2) and PEG1/MEST in a marsupial, the tammar wallaby. Mech Dev (2005) 1.24

Morphometric analysis of testis cord formation in Sox9-EGFP mice. Dev Dyn (2009) 1.22

Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis. Genesis (2004) 1.22

Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling. Clin Cancer Res (2008) 1.22

Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice. Mol Cell Biol (2005) 1.21

The regulatory role of Dicer in folliculogenesis in mice. Mol Cell Endocrinol (2009) 1.20

BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning. Dev Biol (2006) 1.20

Angiomotin regulates visceral endoderm movements during mouse embryogenesis. Curr Biol (2003) 1.20

Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function. FASEB J (2011) 1.19

Sox9 in testis determination. Ann N Y Acad Sci (2005) 1.19

Twist plays an essential role in FGF and SHH signal transduction during mouse limb development. Dev Biol (2002) 1.19

Recent assembly of an imprinted domain from non-imprinted components. PLoS Genet (2006) 1.17

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation. J Clin Invest (2010) 1.17

Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice. Physiol Genomics (2007) 1.17

Horizontal basal cells are multipotent progenitors in normal and injured adult olfactory epithelium. Stem Cells (2008) 1.16

Maternal regulation of milk composition, milk production, and pouch young development during lactation in the tammar wallaby (Macropus eugenii ). Biol Reprod (2003) 1.15

Physical map of two tammar wallaby chromosomes: a strategy for mapping in non-model mammals. Chromosome Res (2008) 1.15

Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex. Development (2005) 1.12

The marsupial placenta: a phylogenetic analysis. J Exp Zool A Comp Exp Biol (2003) 1.11

Postnatal deletion of Wnt7a inhibits uterine gland morphogenesis and compromises adult fertility in mice. Biol Reprod (2011) 1.10

Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress. Mol Cell Biol (2004) 1.10

Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo. Dev Biol (2008) 1.10

Hoxd13 expression in the developing limbs of the short-tailed fruit bat, Carollia perspicillata. Evol Dev (2005) 1.10

Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform. Proc Natl Acad Sci U S A (2002) 1.08

Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation. Nature (2012) 1.08

Generation of a Twist1 conditional null allele in the mouse. Genesis (2007) 1.08

MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse. Differentiation (2008) 1.07

Genetic studies of the AMH/MIS signaling pathway for Müllerian duct regression. Mol Cell Endocrinol (2003) 1.07

Somal positioning and dendritic growth of horizontal cells are regulated by interactions with homotypic neighbors. Eur J Neurosci (2008) 1.07

Snm1-deficient mice exhibit accelerated tumorigenesis and susceptibility to infection. Mol Cell Biol (2005) 1.07