PubRank

Andrzej Bartke

Author PubWeight™ 147.03‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The endocrine regulation of aging by insulin-like signals. Science 2003 8.10
2 Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. Proc Natl Acad Sci U S A 2006 3.04
3 Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity. J Gerontol A Biol Sci Med Sci 2003 2.67
4 Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. Am J Physiol Endocrinol Metab 2005 2.59
5 Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice. J Gerontol A Biol Sci Med Sci 2005 2.28
6 The critical role of metabolic pathways in aging. Diabetes 2012 2.12
7 Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/binding protein knockout mice. J Gerontol A Biol Sci Med Sci 2009 2.08
8 Diet and aging. Cell Metab 2008 2.05
9 Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction. Endocrinology 2004 1.90
10 Delayed and accelerated aging share common longevity assurance mechanisms. PLoS Genet 2008 1.76
11 Insulin sensitivity as a key mediator of growth hormone actions on longevity. J Gerontol A Biol Sci Med Sci 2009 1.69
12 Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity. PLoS One 2009 1.67
13 Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Proc Natl Acad Sci U S A 2008 1.65
14 Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice. Mol Endocrinol 2002 1.61
15 Duration of rapamycin treatment has differential effects on metabolism in mice. Cell Metab 2013 1.61
16 Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice. Am J Physiol Heart Circ Physiol 2008 1.55
17 Progressive loss of SIRT1 with cell cycle withdrawal. Aging Cell 2006 1.54
18 Additive regulation of hepatic gene expression by dwarfism and caloric restriction. Physiol Genomics 2004 1.50
19 Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice. Neurobiol Aging 2005 1.49
20 Time to talk SENS: critiquing the immutability of human aging. Ann N Y Acad Sci 2002 1.42
21 Alterations in oxygen consumption, respiratory quotient, and heat production in long-lived GHRKO and Ames dwarf mice, and short-lived bGH transgenic mice. J Gerontol A Biol Sci Med Sci 2009 1.42
22 The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer. Crit Rev Oncol Hematol 2013 1.41
23 Biological approaches to mechanistically understand the healthy life span extension achieved by calorie restriction and modulation of hormones. J Gerontol A Biol Sci Med Sci 2009 1.36
24 Stress resistance and aging: influence of genes and nutrition. Mech Ageing Dev 2006 1.36
25 Adipocytokines and lipid levels in Ames dwarf and calorie-restricted mice. J Gerontol A Biol Sci Med Sci 2006 1.35
26 Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice. FASEB J 2010 1.33
27 Metabolic effects of intra-abdominal fat in GHRKO mice. Aging Cell 2011 1.32
28 Caloric restriction results in decreased expression of peroxisome proliferator-activated receptor superfamily in muscle of normal and long-lived growth hormone receptor/binding protein knockout mice. J Gerontol A Biol Sci Med Sci 2005 1.25
29 MicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging. Aging Cell 2009 1.24
30 Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissues. Mech Ageing Dev 2008 1.24
31 Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice. Exp Gerontol 2005 1.23
32 Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice. Endocrinology 2007 1.23
33 Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan. Am J Physiol Endocrinol Metab 2012 1.23
34 Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence. Exp Eye Res 2005 1.20
35 GH and IGF1: roles in energy metabolism of long-living GH mutant mice. J Gerontol A Biol Sci Med Sci 2012 1.20
36 A novel insight into aging: are there pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner? Aging (Albany NY) 2010 1.18
37 Long-lived growth hormone receptor knockout mice show a delay in age-related changes of body composition and bone characteristics. J Gerontol A Biol Sci Med Sci 2006 1.16
38 PPARs in Calorie Restricted and Genetically Long-Lived Mice. PPAR Res 2007 1.16
39 Caloric restriction and growth hormone receptor knockout: effects on expression of genes involved in insulin action in the heart. Exp Gerontol 2006 1.13
40 Human placental growth hormone causes severe insulin resistance in transgenic mice. Am J Obstet Gynecol 2002 1.11
41 The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice. Mol Endocrinol 2013 1.11
42 The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs). Age (Dordr) 2012 1.10
43 Divergent effects of caloric restriction on gene expression in normal and long-lived mice. J Gerontol A Biol Sci Med Sci 2004 1.10
44 Is altered expression of hepatic insulin-related genes in growth hormone receptor knockout mice due to GH resistance or a difference in biological life spans? J Gerontol A Biol Sci Med Sci 2009 1.09
45 Rapamycin slows aging in mice. Cell Cycle 2012 1.08
46 The consequences of altered somatotropic system on reproduction. Biol Reprod 2004 1.08
47 The growth hormone receptor gene-disrupted mouse fails to respond to an intermittent fasting diet. Aging Cell 2009 1.06
48 Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes. Free Radic Biol Med 2009 1.04
49 Play, copulation, anatomy, and testosterone in gonadally intact male rats prenatally exposed to flutamide. Physiol Behav 2003 1.04
50 What evidence is there for the existence of individual genes with antagonistic pleiotropic effects? Mech Ageing Dev 2005 1.03
51 Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles. Endocrinology 2014 1.02
52 Increased neurogenesis in dentate gyrus of long-lived Ames dwarf mice. Endocrinology 2004 1.02
53 Impact of growth hormone resistance on female reproductive function: new insights from growth hormone receptor knockout mice. Biol Reprod 2002 1.01
54 Long-living growth hormone receptor knockout mice: potential mechanisms of altered stress resistance. Exp Gerontol 2008 1.00
55 Effects of caloric restriction and growth hormone resistance on the expression level of peroxisome proliferator-activated receptors superfamily in liver of normal and long-lived growth hormone receptor/binding protein knockout mice. J Gerontol A Biol Sci Med Sci 2005 1.00
56 Adiponectin in mice with altered GH action: links to insulin sensitivity and longevity? J Endocrinol 2013 0.99
57 The contribution of visceral fat to improved insulin signaling in Ames dwarf mice. Aging Cell 2014 0.98
58 Effects of growth hormone and thyroxine replacement therapy on insulin signaling in Ames dwarf mice. J Gerontol A Biol Sci Med Sci 2010 0.97
59 Effects of caloric restriction and growth hormone resistance on insulin-related intermediates in the skeletal muscle. J Gerontol A Biol Sci Med Sci 2007 0.97
60 Effects of long-term caloric restriction on glucose homeostasis and on the first steps of the insulin signaling system in skeletal muscle of normal and Ames dwarf (Prop1df/Prop1df) mice. Exp Gerontol 2005 0.97
61 Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice. Elife 2013 0.97
62 Growth hormone, inflammation and aging. Pathobiol Aging Age Relat Dis 2012 0.96
63 Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. J Gerontol A Biol Sci Med Sci 2011 0.95
64 Age-related alterations in pituitary and testicular functions in long-lived growth hormone receptor gene-disrupted mice. Endocrinology 2007 0.95
65 Body composition of prolactin-, growth hormone, and thyrotropin-deficient Ames dwarf mice. Endocrine 2003 0.94
66 Smaller cardiac cell size and reduced extra-cellular collagen might be beneficial for hearts of Ames dwarf mice. Int J Biol Sci 2010 0.94
67 C-reactive protein and glucose regulation in familial longevity. Age (Dordr) 2011 0.93
68 Endocrine regulation of heat shock protein mRNA levels in long-lived dwarf mice. Mech Ageing Dev 2009 0.93
69 Puberty is delayed in male growth hormone receptor gene-disrupted mice. J Androl 2002 0.93
70 Adult neurogenesis in the hippocampus of long-lived mice during aging. J Gerontol A Biol Sci Med Sci 2007 0.93
71 Post-transcriptional regulation of IGF1R by key microRNAs in long-lived mutant mice. Aging Cell 2011 0.92
72 Insulin signaling cascade in the hearts of long-lived growth hormone receptor knockout mice: effects of calorie restriction. J Gerontol A Biol Sci Med Sci 2008 0.91
73 The dwarf mutation decreases high dose insulin responses in skeletal muscle, the opposite of effects in liver. Mech Ageing Dev 2003 0.90
74 Prolonged rapamycin treatment led to beneficial metabolic switch. Aging (Albany NY) 2013 0.90
75 Effects of long-term caloric restriction on early steps of the insulin-signaling system in mouse skeletal muscle. J Gerontol A Biol Sci Med Sci 2005 0.90
76 Long-lived Ames dwarf mice: Oxidative damage to mitochondrial DNA in heart and brain. J Am Aging Assoc 2002 0.89
77 Impact papers on aging in 2009. Aging (Albany NY) 2010 0.89
78 Effect of every other day feeding diet on gene expression in normal and in long-lived Ames dwarf mice. Exp Gerontol 2005 0.89
79 Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis. Biol Chem 2010 0.89
80 Morphology of ovaries in laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1. J Ovarian Res 2012 0.89
81 Dietary restriction and life-span. Science 2002 0.87
82 Key regulators of mitochondrial biogenesis are increased in kidneys of growth hormone receptor knockout (GHRKO) mice. Cell Biochem Funct 2011 0.86
83 Transgenic mice overexpressing GH exhibit hepatic upregulation of GH-signaling mediators involved in cell proliferation. J Endocrinol 2008 0.86
84 Testosterone plus low-intensity physical training in late life improves functional performance, skeletal muscle mitochondrial biogenesis, and mitochondrial quality control in male mice. PLoS One 2012 0.86
85 Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone. Cell Cycle 2013 0.85
86 Effects of mild calorie restriction on reproduction, plasma parameters and hepatic gene expression in mice with altered GH/IGF-I axis. Mech Ageing Dev 2007 0.85
87 Decreased expression level of apoptosis-related genes and/or proteins in skeletal muscles, but not in hearts, of growth hormone receptor knockout mice. Exp Biol Med (Maywood) 2011 0.85
88 In vivo analysis of gene expression in long-lived mice lacking the pregnancy-associated plasma protein A (PappA) gene. Exp Gerontol 2010 0.85
89 RasGrf1: genomic imprinting, VSELs, and aging. Aging (Albany NY) 2011 0.85
90 Deletion of growth hormone receptor gene but not visceral fat removal decreases expression of apoptosis-related genes in the kidney-potential mechanism of lifespan extension. Age (Dordr) 2011 0.84
91 Circulating blood leukocyte gene expression profiles: effects of the Ames dwarf mutation on pathways related to immunity and inflammation. Exp Gerontol 2007 0.84
92 IGF-I regulates the age-dependent signaling peptide humanin. Aging Cell 2014 0.84
93 Prevention of neuromusculoskeletal frailty in slow-aging ames dwarf mice: longitudinal investigation of interaction of longevity genes and caloric restriction. PLoS One 2013 0.84
94 Parting messages from current and former editors of the Journal of Andrology. J Androl 2012 0.83
95 Suppression of growth hormone (GH) Janus tyrosine kinase 2/signal transducer and activator of transcription 5 signaling pathway in transgenic mice overexpressing bovine GH. Endocrinology 2004 0.83
96 Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice. J Gerontol A Biol Sci Med Sci 2012 0.83
97 Insulin resistance and cognitive aging in long-lived and short-lived mice. J Gerontol A Biol Sci Med Sci 2005 0.83
98 GH modulates hepatic epidermal growth factor signaling in the mouse. J Endocrinol 2009 0.82
99 Direct and indirect effects of growth hormone receptor ablation on liver expression of xenobiotic metabolizing genes. Am J Physiol Endocrinol Metab 2013 0.82
100 Soy isoflavones modify liver free radical scavenger systems and liver parameters in Sprague-Dawley rats. J Med Food 2004 0.81
101 Sex Differences in Longevity and in Responses to Anti-Aging Interventions: A Mini-Review. Gerontology 2015 0.81
102 Renal pro-apoptotic proteins are reduced by growth hormone resistance but not by visceral fat removal. Biol Chem 2011 0.81
103 Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age. Age (Dordr) 2015 0.81
104 The effect of low and high plasma levels of insulin-like growth factor-1 (IGF-1) on the morphology of major organs: studies of Laron dwarf and bovine growth hormone transgenic (bGHTg) mice. Histol Histopathol 2013 0.80
105 Metabolic alterations due to caloric restriction and every other day feeding in normal and growth hormone receptor knockout mice. J Gerontol A Biol Sci Med Sci 2013 0.80
106 Evidence that growth hormone exerts a feedback effect on stomach ghrelin production and secretion. Exp Biol Med (Maywood) 2003 0.80
107 The effect of calorie restriction on the presence of apoptotic ovarian cells in normal wild type mice and low-plasma-IGF-1 Laron dwarf mice. J Ovarian Res 2013 0.80
108 Alcohol suppresses insulin-like growth factor-1 gene expression in prepubertal transgenic female mice overexpressing the bovine growth hormone gene. Alcohol Clin Exp Res 2002 0.80
109 Mild calorie restriction does not affect testosterone levels and testicular gene expression in mutant mice. Exp Biol Med (Maywood) 2007 0.79
110 Decreased thyroid follicle size in dwarf mice may suggest the role of growth hormone signaling in thyroid growth regulation. Thyroid Res 2012 0.79
111 The slow-aging growth hormone receptor/binding protein gene-disrupted (GHR-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty. Age (Dordr) 2013 0.79
112 Preservation of blood glucose homeostasis in slow-senescing somatotrophism-deficient mice subjected to intermittent fasting begun at middle or old age. Age (Dordr) 2014 0.79
113 Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice. Growth Horm IGF Res 2012 0.79
114 Do Ames dwarf and calorie-restricted mice share common effects on age-related pathology? Pathobiol Aging Age Relat Dis 2013 0.79
115 Pioglitazone does not improve insulin signaling in mice with GH over-expression. J Endocrinol 2013 0.78
116 Desensitization of the JAK2/STAT5 GH signaling pathway associated with increased CIS protein content in liver of pregnant mice. Am J Physiol Endocrinol Metab 2005 0.78
117 Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice. Aging (Albany NY) 2015 0.78
118 Growth hormone modulation of EGF-induced PI3K-Akt pathway in mice liver. Cell Signal 2011 0.78
119 The role of insulin-like growth factor-I in neuroendocrine function and the consequent effects on sexual maturation: inferences from animal models. Reprod Biol 2003 0.78
120 Ames dwarf (Prop1(df)/Prop1(df)) mice display increased sensitivity of the major GH-signaling pathways in liver and skeletal muscle. Growth Horm IGF Res 2009 0.77
121 Humoral immune response in mice over-expressing or deficient in growth hormone. Exp Biol Med (Maywood) 2002 0.77
122 Downregulation of the ACE2/Ang-(1-7)/Mas axis in transgenic mice overexpressing GH. J Endocrinol 2014 0.77
123 Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging. Aging Cell 2014 0.77
124 Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries. Age (Dordr) 2014 0.77
125 The second international conference "genetics of aging and longevity". Aging (Albany NY) 2012 0.77
126 Increased in vivo phosphorylation of insulin receptor at serine 994 in the liver of obese insulin-resistant Zucker rats. J Endocrinol 2004 0.77
127 The effects of aging and genotype on NMDA receptor expression in growth hormone receptor knockout (GHRKO) mice. J Gerontol A Biol Sci Med Sci 2011 0.77
128 Tachykinins and their possible modulatory role on testicular function: a review. Int J Androl 2003 0.76
129 Comment on: Kloting et al. (2008) Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth: Diabetes 57:2074-2082. Diabetes 2009 0.75
130 Do altered energy metabolism or spontaneous locomotion 'mediate' decelerated senescence? Aging Cell 2015 0.75
131 Histological changes of testes in growth hormone transgenic mice with high plasma level of GH and insulin-like growth factor-1. Folia Histochem Cytobiol 2015 0.75
132 A summary of the Proceedings of the Ninth International Symposium on the Neurobiology and Neuroendocrinology of Aging Bregenz, Austria, July 20-25, 2008. Exp Gerontol 2008 0.75
133 A summary of the proceedings of the eighth international symposium on the neurobiology and neuroendocrinology of aging. Exp Gerontol 2006 0.75
134 Age. Introduction. Age (Dordr) 2006 0.75
135 Effects of every-other-day feeding on prolactin regulatory mechanism in transgenic human growth hormone mice. Exp Biol Med (Maywood) 2008 0.75
136 Corrigendum. Cell Cycle 2015 0.75
137 Declining sperm counts and increases in testicular cancer: a legacy of the cold war? J Androl 2008 0.75
138 Special issue on the endocrinology of aging. Mol Cell Endocrinol 2008 0.75
139 Miller time. Aging Cell 2011 0.75
140 Proceedings of the seventh international symposium on the neurobiology and neuroendocrinology of aging, Bregenz, Austria, July 18-23, 2004. Exp Gerontol 2004 0.75
141 Effects of soy protein and soy phytochemicals on mammary tumor development in female transgenic mice overexpressing human pituitary growth hormone. J Med Food 2005 0.75