Published in J Immunol on July 01, 2008
Subsets of nonclonal neighboring CD4+ T cells specifically regulate the frequency of individual antigen-reactive T cells. Immunity (2012) 2.15
Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection. Blood (2013) 1.63
Induction of B-cell immune tolerance by antigen-modified cytotoxic T lymphocytes. Transplantation (2010) 1.43
αβT cell receptors expressed by CD4(-)CD8αβ(-) intraepithelial T cells drive their fate into a unique lineage with unusual MHC reactivities. Immunity (2014) 1.15
T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice. Immunology (2012) 1.03
Nature and nurture in Foxp3(+) regulatory T cell development, stability, and function. Hum Immunol (2011) 1.02
T cell receptor CDR3 sequence but not recognition characteristics distinguish autoreactive effector and Foxp3(+) regulatory T cells. Immunity (2009) 0.99
Discrete TCR repertoires and CDR3 features distinguish effector and Foxp3+ regulatory T lymphocytes in myelin oligodendrocyte glycoprotein-induced experimental allergic encephalomyelitis. J Immunol (2010) 0.96
Monitoring the Dynamics of T Cell Clonal Diversity Using Recombinant Peptide:MHC Technology. Front Immunol (2013) 0.93
Subtle affinity-enhancing mutations in a myelin oligodendrocyte glycoprotein-specific TCR alter specificity and generate new self-reactivity. J Immunol (2009) 0.91
Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1. Cell Death Differ (2015) 0.89
Multiple sclerosis: autoimmunity and viruses. Curr Opin Rheumatol (2013) 0.89
Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics. PLoS One (2012) 0.88
A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis. J Immunol (2011) 0.86
T cell receptors in an IL-10-secreting amino acid copolymer-specific regulatory T cell line that mediates bystander immunosuppression. Proc Natl Acad Sci U S A (2009) 0.83
Rational design of T cell receptors with enhanced sensitivity for antigen. PLoS One (2011) 0.83
Altered differentiation, diminished pathogenicity, and regulatory activity of myelin-specific T cells expressing an enhanced affinity TCR. J Immunol (2011) 0.82
Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy. Arch Immunol Ther Exp (Warsz) (2010) 0.78
Preferential Use of Public TCR during Autoimmune Encephalomyelitis. J Immunol (2016) 0.77
Towards the generation of B-cell receptor retrogenic mice. PLoS One (2014) 0.76
Regulatory T cells play a role in T-cell receptor CDR2 peptide regulation of experimental autoimmune encephalomyelitis. Immunology (2012) 0.75
Autoimmune susceptibility imposed by public TCRβ chains. Sci Rep (2016) 0.75
Evolving Approaches in the Identification of Allograft-reactive T and B Cells in Mice and Humans. Transplantation (2017) 0.75
Rapid identification and expression of human TCRs in retrogenic mice. J Immunol Methods (2016) 0.75
CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol (2002) 12.73
Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J Exp Med (1981) 12.03
Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity (2007) 9.26
Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. J Exp Med (2003) 6.73
Massive expansion of antigen-specific CD8+ T cells during an acute virus infection. Immunity (1998) 6.29
Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'. J Gen Virol (2001) 4.25
The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences. J Gen Virol (2001) 3.95
Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. J Exp Med (2005) 3.63
An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A (1999) 3.15
Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties. Immunity (2004) 3.06
Generation of T-cell receptor retrogenic mice. Nat Protoc (2006) 3.05
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation. Immunity (2003) 3.04
T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity. Immunity (2006) 3.02
Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice. Nat Methods (2006) 2.87
Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol (1989) 2.78
T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire. Annu Rev Immunol (2001) 2.51
Progression of autoimmune diabetes driven by avidity maturation of a T-cell population. Nature (2000) 2.39
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood. J Clin Invest (2003) 2.37
Epitope dominance, competition and T cell affinity maturation. Curr Opin Immunol (2003) 2.09
Regulatory T cells in spontaneous autoimmune encephalomyelitis. Immunol Rev (2001) 1.99
Increased competition for antigen during priming negatively impacts the generation of memory CD4 T cells. Proc Natl Acad Sci U S A (2007) 1.71
Role of TCR specificity in CD4+ CD25+ regulatory T-cell selection. Immunol Rev (2006) 1.51
CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation. J Exp Med (2001) 1.38
T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo. J Exp Med (2000) 1.30
Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells. Proc Natl Acad Sci U S A (2002) 1.22
Diabetes incidence is unaltered in glutamate decarboxylase 65-specific TCR retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene transfer. J Immunol (2004) 1.13
Apoptotic signal transduction and T cell tolerance. Autoimmunity (2007) 1.04
Binding energetics of T-cell receptors: correlation with immunological consequences. Immunol Today (1999) 0.96
Distinct T cell recognition of naturally processed and cryptic epitopes within the immunodominant 35-55 region of myelin oligodendrocyte glycoprotein. J Neuroimmunol (2006) 0.95
T-cell avidity and tuning: the flexible connection between tolerance and autoimmunity. Int Rev Immunol (2006) 0.88
Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-zeta chimeric receptor. J Immunol (2008) 0.86
TCR-CD4 and TCR-TCR interactions as distinctive mechanisms for the induction of increased intracellular calcium in T-cell signalling. J Immunol (1993) 0.85
Defective cell cycle induction by IL-2 in naive T-cells antigen stimulated in the presence of refractory T-lymphocytes. Int Immunol (2006) 0.83
A novel protective model against experimental allergic encephalomyelitis in mice expressing a transgenic TCR-specific for myelin oligodendrocyte glycoprotein. J Neuroimmunol (2004) 0.82
Tracking antigen-specific CD8+ T cells in the rat using MHC class I multimers. J Immunol Methods (2006) 0.79
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med (2015) 5.71
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality. Sci Transl Med (2011) 2.97
Microvascular lifeboats: a stepwise approach to intraoperative venous congestion in DIEP flap breast reconstruction. Plast Reconstr Surg (2014) 2.80
Functional genomic analysis of the response of HIV-1-infected lymphatic tissue to antiretroviral therapy. J Infect Dis (2004) 2.68
Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease. Neuron (2010) 2.20
Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines. Immunity (2013) 2.08
A surface on the androgen receptor that allosterically regulates coactivator binding. Proc Natl Acad Sci U S A (2007) 1.97
A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta. J Immunol (2007) 1.91
Identification of errors introduced during high throughput sequencing of the T cell receptor repertoire. BMC Genomics (2011) 1.87
Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2. Immunity (2004) 1.77
Mitigation of experimental allergic encephalomyelitis by TGF-beta induced Foxp3+ regulatory T lymphocytes through the induction of anergy and infectious tolerance. J Immunol (2008) 1.71
The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor. J Biol Chem (2004) 1.66
Effects of micronutrients on growth of children under 5 y of age: meta-analyses of single and multiple nutrient interventions. Am J Clin Nutr (2008) 1.47
A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta. J Immunol (2007) 1.47
Induction of B-cell immune tolerance by antigen-modified cytotoxic T lymphocytes. Transplantation (2010) 1.43
Targeting autoantigen-specific T cells and suppression of autoimmune encephalomyelitis with receptor-modified T lymphocytes. Nat Biotechnol (2002) 1.42
Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators. J Biol Chem (2005) 1.32
Epm2a suppresses tumor growth in an immunocompromised host by inhibiting Wnt signaling. Cancer Cell (2006) 1.28
Host immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with Staphylococcus aureus infections. PLoS One (2012) 1.28
Premedication with acetaminophen or diphenhydramine for transfusion with leucoreduced blood products in children. Br J Haematol (2005) 1.21
Differential SERM effects on corepressor binding dictate ERalpha activity in vivo. J Biol Chem (2002) 1.20
IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Proc Natl Acad Sci U S A (2005) 1.16
Early complications in children with acute lymphoblastic leukemia presenting with hyperleukocytosis. Pediatr Blood Cancer (2005) 1.14
TCR-dependent transformation of mature memory phenotype T cells in mice. J Clin Invest (2011) 1.13
Rearrangements in thyroid hormone receptor charge clusters that stabilize bound 3,5',5-triiodo-L-thyronine and inhibit homodimer formation. J Biol Chem (2005) 1.10
Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor. Mol Endocrinol (2007) 1.10
S-palmitoylation of gamma-secretase subunits nicastrin and APH-1. J Biol Chem (2008) 1.09
Differential requirement for IFN-gamma in CTL maturation in acute murine graft-versus-host disease. J Immunol (2004) 1.09
A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding. Sci STKE (2006) 1.08
Thyroid hormone response element organization dictates the composition of active receptor. J Biol Chem (2007) 1.07
Structural basis of coactivation of liver receptor homolog-1 by β-catenin. Proc Natl Acad Sci U S A (2011) 1.06
Gaining ligand selectivity in thyroid hormone receptors via entropy. Proc Natl Acad Sci U S A (2009) 1.05
Low-dose exposure to inorganic mercury accelerates disease and mortality in acquired murine lupus. Environ Health Perspect (2003) 1.05
In vivo CD86 blockade inhibits CD4+ T cell activation, whereas CD80 blockade potentiates CD8+ T cell activation and CTL effector function. J Immunol (2002) 1.05
Growth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cells. Cytoskeleton (Hoboken) (2012) 1.02
Negative predictive value of endoscopic ultrasound in a large series of patients with a clinical suspicion of pancreatic cancer. Am J Gastroenterol (2005) 1.02
Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Blood (2004) 0.99
T cell receptor CDR3 sequence but not recognition characteristics distinguish autoreactive effector and Foxp3(+) regulatory T cells. Immunity (2009) 0.99
Identification of a murine CD28 dileucine motif that suppresses single-chain chimeric T-cell receptor expression and function. Blood (2003) 0.98
Soluble γ-secretase modulators selectively inhibit the production of the 42-amino acid amyloid β peptide variant and augment the production of multiple carboxy-truncated amyloid β species. Biochemistry (2014) 0.98
Both apoptosis and complement membrane attack complex deposition are major features of murine acute graft-vs.-host disease. Exp Mol Pathol (2005) 0.97
Discrete TCR repertoires and CDR3 features distinguish effector and Foxp3+ regulatory T lymphocytes in myelin oligodendrocyte glycoprotein-induced experimental allergic encephalomyelitis. J Immunol (2010) 0.96
SureSmile: a report of clinical findings. J Clin Orthod (2005) 0.95
ERbeta Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus. Nucl Recept (2003) 0.94
4-Pyridylanilinothiazoles that selectively target von Hippel-Lindau deficient renal cell carcinoma cells by inducing autophagic cell death. J Med Chem (2010) 0.94
Clinical and biologic features and treatment outcome of children with newly diagnosed acute myeloid leukemia and hyperleukocytosis. Cancer (2008) 0.93
Early identification and control of carbapenemase-producing Klebsiella pneumoniae, originating from contaminated endoscopic equipment. Am J Infect Control (2012) 0.93
Neuronal HIF-1 alpha protein and VEGFR-2 immunoreactivity in functionally related motor areas following a focal M1 infarct. J Cereb Blood Flow Metab (2007) 0.93
Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol. Mol Biol Cell (2013) 0.92
β-cell metabolic alterations under chronic nutrient overload in rat and human islets. Islets (2012) 0.92
Antigen nonspecific suppression of T cell responses by activated stimulation-refractory CD4+ T cells. J Immunol (2004) 0.91
Uncoupling of IL-2 signaling from cell cycle progression in naive CD4+ T cells by regulatory CD4+CD25+ T lymphocytes. J Immunol (2005) 0.91
IL-10-dependent suppression of experimental allergic encephalomyelitis by Th2-differentiated, anti-TCR redirected T lymphocytes. J Immunol (2005) 0.91
Subtle affinity-enhancing mutations in a myelin oligodendrocyte glycoprotein-specific TCR alter specificity and generate new self-reactivity. J Immunol (2009) 0.91
A case of hemoglobin SC disease with cold agglutinin-induced hemolysis. Am J Hematol (2005) 0.90
Increased severity of murine lupus in female mice is due to enhanced expansion of pathogenic T cells. J Immunol (2003) 0.89
Post-traumatic hypoxia is associated with prolonged cerebral cytokine production, higher serum biomarker levels, and poor outcome in patients with severe traumatic brain injury. J Neurotrauma (2014) 0.89
T cell reactivity during infectious mononucleosis and persistent gammaherpesvirus infection in mice. J Immunol (2004) 0.88
A conserved lysine in the estrogen receptor DNA binding domain regulates ligand activation profiles at AP-1 sites, possibly by controlling interactions with a modulating repressor. Nucl Recept (2004) 0.88
Complex actions of thyroid hormone receptor antagonist NH-3 on gene promoters in different cell lines. Mol Cell Endocrinol (2008) 0.87
Stop the drama Downunder: a social marketing campaign increases HIV/sexually transmitted infection knowledge and testing in Australian gay men. Sex Transm Dis (2012) 0.87
Human papillomavirus and abnormal Pap test results in Vietnamese-American women: a pilot case-control study. J Low Genit Tract Dis (2004) 0.87
Allosteric conversation in the androgen receptor ligand-binding domain surfaces. Mol Endocrinol (2012) 0.87
Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-zeta chimeric receptor. J Immunol (2008) 0.86
Mapping of two antigenic domains on the NS3 protein of the pestivirus bovine viral diarrhea virus. Vet Microbiol (2005) 0.86
A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis. J Immunol (2011) 0.86
Context and location dependence of adaptive Foxp3(+) regulatory T cell formation during immunopathological conditions. Cell Immunol (2012) 0.86
Converting antigen-specific diabetogenic CD4 and CD8 T cells to TGF-beta producing non-pathogenic regulatory cells following FoxP3 transduction. J Autoimmun (2007) 0.86
Pathogenic T cells in murine lupus exhibit spontaneous signaling activity through phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways. Arthritis Rheum (2003) 0.85
The T cell response to IL-10 alters cellular dynamics and paradoxically promotes central nervous system autoimmunity. J Immunol (2012) 0.84
Risk of adult acute and chronic myeloid leukemia with cigarette smoking and cessation. Cancer Epidemiol (2013) 0.83
Risk factors associated with hemoglobin levels and nutritional status among Brazilian children attending daycare centers in Sao Paulo City, Brazil. Arch Latinoam Nutr (2010) 0.83
Defective cell cycle induction by IL-2 in naive T-cells antigen stimulated in the presence of refractory T-lymphocytes. Int Immunol (2006) 0.83
Dependence of stress resistance on a spore coat heteropolysaccharide in Dictyostelium. Eukaryot Cell (2008) 0.83
Laparoscopic distal pancreatic resection. Am Surg (2005) 0.83
Rational design of T cell receptors with enhanced sensitivity for antigen. PLoS One (2011) 0.83
Altered differentiation, diminished pathogenicity, and regulatory activity of myelin-specific T cells expressing an enhanced affinity TCR. J Immunol (2011) 0.82
Immunophototherapy using PDT combined with rapid intratumoral dendritic cell injection. Photochem Photobiol (2008) 0.82
Activin a release into cerebrospinal fluid in a subset of patients with severe traumatic brain injury. J Neurotrauma (2006) 0.82
Diversification and senescence of Foxp3+ regulatory T cells during experimental autoimmune encephalomyelitis. Eur J Immunol (2013) 0.81
Interrelationship between growth and development in low and middle income countries. Nestle Nutr Workshop Ser Pediatr Program (2010) 0.80
Transfusion-associated immune modulation: a reason to TRIM platelet transfusions? Transfusion (2008) 0.79
Mid-upper-arm and calf circumferences are useful predictors of underweight in women of reproductive age in northern Vietnam. Food Nutr Bull (2014) 0.79
Stress in pregnancy activates neurosteroid production in the fetal brain. Neuroendocrinology (2006) 0.79
Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy. Arch Immunol Ther Exp (Warsz) (2010) 0.78
Granulocyte/Monocyte Adsorptive Apheresis in Moderate to Severe Ulcerative Colitis--Effective or Not? Digestion (2015) 0.78
Prediction of CD34(+) cell yield in hematopoietic cell products from children by peripheral blood CD34(+) cell counts. Cytotherapy (2012) 0.78
Distinct ligand-dependent and independent modes of thyroid hormone receptor (TR)/PGC-1α interaction. J Steroid Biochem Mol Biol (2012) 0.78
An Essix intrusion appliance. J Clin Orthod (2003) 0.78