| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Growth factors, matrices, and forces combine and control stem cells.
|
Science
|
2009
|
8.46
|
|
2
|
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
|
Nat Cell Biol
|
2008
|
3.44
|
|
3
|
Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates.
|
PLoS One
|
2008
|
3.08
|
|
4
|
Niche-mediated control of human embryonic stem cell self-renewal and differentiation.
|
EMBO J
|
2007
|
2.91
|
|
5
|
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.
|
Cell
|
2011
|
2.89
|
|
6
|
Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling.
|
Cell Stem Cell
|
2012
|
2.58
|
|
7
|
Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories.
|
Stem Cells
|
2008
|
2.34
|
|
8
|
A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues.
|
Tissue Eng Part A
|
2012
|
1.95
|
|
9
|
Controlled, scalable embryonic stem cell differentiation culture.
|
Stem Cells
|
2004
|
1.87
|
|
10
|
Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems.
|
Biotechnol Bioeng
|
2002
|
1.85
|
|
11
|
The systematic production of cells for cell therapies.
|
Cell Stem Cell
|
2008
|
1.71
|
|
12
|
Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor.
|
Biotechnol Bioeng
|
2009
|
1.61
|
|
13
|
Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment.
|
Cell Stem Cell
|
2007
|
1.56
|
|
14
|
Functional immobilization of signaling proteins enables control of stem cell fate.
|
Nat Methods
|
2008
|
1.52
|
|
15
|
Dynamic interaction networks in a hierarchically organized tissue.
|
Mol Syst Biol
|
2010
|
1.51
|
|
16
|
Shear-controlled single-step mouse embryonic stem cell expansion and embryoid body-based differentiation.
|
Stem Cells
|
2005
|
1.51
|
|
17
|
Cell-cell interaction networks regulate blood stem and progenitor cell fate.
|
Mol Syst Biol
|
2009
|
1.49
|
|
18
|
A global assessment of stem cell engineering.
|
Tissue Eng Part A
|
2014
|
1.38
|
|
19
|
High-throughput generation of hydrogel microbeads with varying elasticity for cell encapsulation.
|
Biomaterials
|
2010
|
1.37
|
|
20
|
Alternative induced pluripotent stem cell characterization criteria for in vitro applications.
|
Cell Stem Cell
|
2009
|
1.36
|
|
21
|
Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation.
|
Biomaterials
|
2010
|
1.35
|
|
22
|
Don't look: growing clonal versus nonclonal neural stem cell colonies.
|
Stem Cells
|
2008
|
1.33
|
|
23
|
Enabling stem cell therapies through synthetic stem cell-niche engineering.
|
J Clin Invest
|
2010
|
1.31
|
|
24
|
Design and formulation of functional pluripotent stem cell-derived cardiac microtissues.
|
Proc Natl Acad Sci U S A
|
2013
|
1.29
|
|
25
|
Development of a perfusion fed bioreactor for embryonic stem cell-derived cardiomyocyte generation: oxygen-mediated enhancement of cardiomyocyte output.
|
Biotechnol Bioeng
|
2005
|
1.28
|
|
26
|
Understanding cellular networks to improve hematopoietic stem cell expansion cultures.
|
Curr Opin Biotechnol
|
2006
|
1.25
|
|
27
|
High-throughput combinatorial cell co-culture using microfluidics.
|
Integr Biol (Camb)
|
2011
|
1.25
|
|
28
|
Spatial organization of embryonic stem cell responsiveness to autocrine gp130 ligands reveals an autoregulatory stem cell niche.
|
Stem Cells
|
2006
|
1.24
|
|
29
|
Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures.
|
Nat Methods
|
2012
|
1.23
|
|
30
|
Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control.
|
PLoS Comput Biol
|
2007
|
1.22
|
|
31
|
LIF-mediated control of embryonic stem cell self-renewal emerges due to an autoregulatory loop.
|
FASEB J
|
2007
|
1.21
|
|
32
|
PERT: a method for expression deconvolution of human blood samples from varied microenvironmental and developmental conditions.
|
PLoS Comput Biol
|
2012
|
1.18
|
|
33
|
Sustained in vitro expansion of bone progenitors is cell density dependent.
|
Stem Cells
|
2004
|
1.12
|
|
34
|
Geometric control of cardiomyogenic induction in human pluripotent stem cells.
|
Tissue Eng Part A
|
2011
|
1.11
|
|
35
|
Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue.
|
Proc Natl Acad Sci U S A
|
2009
|
1.10
|
|
36
|
Ligand/receptor signaling threshold (LIST) model accounts for gp130-mediated embryonic stem cell self-renewal responses to LIF and HIL-6.
|
Stem Cells
|
2002
|
1.09
|
|
37
|
Dynamic changes in cellular and microenvironmental composition can be controlled to elicit in vitro human hematopoietic stem cell expansion.
|
Exp Hematol
|
2005
|
1.09
|
|
38
|
Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens.
|
PLoS One
|
2009
|
1.03
|
|
39
|
Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion.
|
Exp Hematol
|
2003
|
1.02
|
|
40
|
The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells.
|
Biomaterials
|
2010
|
1.01
|
|
41
|
Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells.
|
Proc Natl Acad Sci U S A
|
2012
|
1.00
|
|
42
|
Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner.
|
Stem Cells
|
2008
|
0.98
|
|
43
|
Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling.
|
Blood
|
2013
|
0.98
|
|
44
|
Systematic engineering of 3D pluripotent stem cell niches to guide blood development.
|
Biomaterials
|
2011
|
0.97
|
|
45
|
HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity.
|
Toxicol Appl Pharmacol
|
2012
|
0.96
|
|
46
|
Clinically relevant expansion of hematopoietic stem cells with conserved function in a single-use, closed-system bioprocess.
|
Biol Blood Marrow Transplant
|
2006
|
0.96
|
|
47
|
Soluble factor cross-talk between human bone marrow-derived hematopoietic and mesenchymal cells enhances in vitro CFU-F and CFU-O growth and reveals heterogeneity in the mesenchymal progenitor cell compartment.
|
Blood
|
2005
|
0.96
|
|
48
|
Supplementation-dependent differences in the rates of embryonic stem cell self-renewal, differentiation, and apoptosis.
|
Biotechnol Bioeng
|
2003
|
0.95
|
|
49
|
High-throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias.
|
Nat Methods
|
2013
|
0.94
|
|
50
|
A non-contact suspension culture approach to the culture of osteogenic cells derived from a CD49elow subpopulation of human bone marrow-derived cells.
|
Biotechnol Bioeng
|
2007
|
0.94
|
|
51
|
Creation of mouse embryonic stem cell-derived cardiac cell sheets.
|
Biomaterials
|
2011
|
0.93
|
|
52
|
Analysis of the temporal and concentration-dependent effects of BMP-4, VEGF, and TPO on development of embryonic stem cell-derived mesoderm and blood progenitors in a defined, serum-free media.
|
Exp Hematol
|
2008
|
0.92
|
|
53
|
Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics.
|
Biotechnol Bioeng
|
2011
|
0.92
|
|
54
|
Clonal evolution of stem and differentiated cells can be predicted by integrating cell-intrinsic and -extrinsic parameters.
|
Biotechnol Appl Biochem
|
2005
|
0.91
|
|
55
|
Fiber alignment and coculture with fibroblasts improves the differentiated phenotype of murine embryonic stem cell-derived cardiomyocytes for cardiac tissue engineering.
|
Biotechnol Bioeng
|
2011
|
0.90
|
|
56
|
Phenotypic analysis of human embryonic stem cells.
|
Curr Protoc Stem Cell Biol
|
2007
|
0.90
|
|
57
|
Oct4 is required ~E7.5 for proliferation in the primitive streak.
|
PLoS Genet
|
2013
|
0.89
|
|
58
|
The AC133+CD38-, but not the rhodamine-low, phenotype tracks LTC-IC and SRC function in human cord blood ex vivo expansion cultures.
|
Blood
|
2009
|
0.89
|
|
59
|
Synthetic peptide arrays for pathway-level protein monitoring by liquid chromatography-tandem mass spectrometry.
|
Mol Cell Proteomics
|
2010
|
0.87
|
|
60
|
Development of a gene-trap vector with a highly sensitive fluorescent protein reporter system for expression profiling.
|
Genesis
|
2008
|
0.86
|
|
61
|
Engineered heart tissue enables study of residual undifferentiated embryonic stem cell activity in a cardiac environment.
|
Biotechnol Bioeng
|
2010
|
0.86
|
|
62
|
Tissue engineering 2.0: guiding self-organization during pluripotent stem cell differentiation.
|
Curr Opin Biotechnol
|
2012
|
0.85
|
|
63
|
Towards predictive models of stem cell fate.
|
Cytotechnology
|
2003
|
0.85
|
|
64
|
Seeding bioreactor-produced embryonic stem cell-derived cardiomyocytes on different porous, degradable, polyurethane scaffolds reveals the effect of scaffold architecture on cell morphology.
|
Tissue Eng Part A
|
2008
|
0.85
|
|
65
|
Real-time monitoring and control of soluble signaling factors enables enhanced progenitor cell outputs from human cord blood stem cell cultures.
|
Biotechnol Bioeng
|
2013
|
0.84
|
|
66
|
Fluorescence activated cell sorting reveals heterogeneous and cell non-autonomous osteoprogenitor differentiation in fetal rat calvaria cell populations.
|
J Cell Biochem
|
2003
|
0.84
|
|
67
|
An automated system for delivery of an unstable transcription factor to hematopoietic stem cell cultures.
|
Biotechnol Bioeng
|
2009
|
0.84
|
|
68
|
High density continuous production of murine pluripotent cells in an acoustic perfused bioreactor at different oxygen concentrations.
|
Biotechnol Bioeng
|
2012
|
0.83
|
|
69
|
Surfaceome profiling reveals regulators of neural stem cell function.
|
Stem Cells
|
2014
|
0.82
|
|
70
|
Quantitative screening of embryonic stem cell differentiation: endoderm formation as a model.
|
Biotechnol Bioeng
|
2004
|
0.82
|
|
71
|
Scalable production of embryonic stem cell-derived cells.
|
Methods Mol Biol
|
2005
|
0.82
|
|
72
|
Engineered heart tissue model of diabetic myocardium.
|
Tissue Eng Part A
|
2011
|
0.81
|
|
73
|
Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK-STAT signaling.
|
Integr Biol (Camb)
|
2012
|
0.81
|
|
74
|
Patterning mouse and human embryonic stem cells using micro-contact printing.
|
Methods Mol Biol
|
2009
|
0.81
|
|
75
|
miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.
|
Cancer Cell
|
2016
|
0.80
|
|
76
|
Synergy between erythropoietin and stem cell factor during erythropoiesis can be quantitatively described without co-signaling effects.
|
Biotechnol Bioeng
|
2008
|
0.79
|
|
77
|
A microgroove patterned multiwell cell culture plate for high-throughput studies of cell alignment.
|
Biotechnol Bioeng
|
2014
|
0.78
|
|
78
|
Blood stem cell products: toward sustainable benchmarks for clinical translation.
|
Bioessays
|
2013
|
0.78
|
|
79
|
Integrative network analysis of signaling in human CD34(+) hematopoietic progenitor cells by global phosphoproteomic profiling using TiO2 enrichment combined with 2D LC-MS/MS and pathway mapping.
|
Proteomics
|
2013
|
0.78
|
|
80
|
The opportunity of stem cell bioengineering.
|
Biotechnol Bioeng
|
2004
|
0.77
|
|
81
|
Engineering cardiac healing using embryonic stem cell-derived cardiac cell seeded constructs.
|
Front Biosci
|
2007
|
0.76
|
|
82
|
Two-dimensional arrays of cell-laden polymer hydrogel modules.
|
Biomicrofluidics
|
2016
|
0.75
|
|
83
|
Pairing cells to enhance fusion.
|
Nat Methods
|
2009
|
0.75
|
|
84
|
Corrigendum: Genome-wide characterization of the routes to pluripotency.
|
Nature
|
2015
|
0.75
|
|
85
|
Two-color image analysis discriminates between mineralized and unmineralized bone nodules in vitro.
|
Biotechniques
|
2003
|
0.75
|
|
86
|
Signal processing underlying extrinsic control of stem cell fate.
|
Curr Opin Hematol
|
2004
|
0.75
|