Published in Cell Stem Cell on February 03, 2012
Effect of mutation order on myeloproliferative neoplasms. N Engl J Med (2015) 5.59
Hematopoietic stem cell niche maintenance during homeostasis and regeneration. Nat Med (2014) 2.05
Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal. Science (2014) 1.56
An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy. Nat Biotechnol (2016) 1.44
A global assessment of stem cell engineering. Tissue Eng Part A (2014) 1.38
Human pluripotent stem cell culture: considerations for maintenance, expansion, and therapeutics. Cell Stem Cell (2014) 1.10
Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence. Transplantation (2014) 0.98
Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling. Blood (2013) 0.98
Intercellular network structure and regulatory motifs in the human hematopoietic system. Mol Syst Biol (2014) 0.96
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy. J Exp Med (2013) 0.96
Automated method for the rapid and precise estimation of adherent cell culture characteristics from phase contrast microscopy images. Biotechnol Bioeng (2013) 0.95
Engineering three-dimensional stem cell morphogenesis for the development of tissue models and scalable regenerative therapeutics. Ann Biomed Eng (2013) 0.94
Concise review: microfluidic technology platforms: poised to accelerate development and translation of stem cell-derived therapies. Stem Cells Transl Med (2013) 0.88
Tissue engineering 2.0: guiding self-organization during pluripotent stem cell differentiation. Curr Opin Biotechnol (2012) 0.85
Concise review: ex vivo expansion of cord blood-derived hematopoietic stem and progenitor cells: basic principles, experimental approaches, and impact in regenerative medicine. Stem Cells Transl Med (2013) 0.85
Real-time monitoring and control of soluble signaling factors enables enhanced progenitor cell outputs from human cord blood stem cell cultures. Biotechnol Bioeng (2013) 0.84
Engineering stem cell expansion. Cell Stem Cell (2012) 0.84
The pharmacology of regenerative medicine. Pharmacol Rev (2013) 0.83
A novel application for a 3-dimensional timelapse assay that distinguishes chemotactic from chemokinetic responses of hematopoietic CD133(+) stem/progenitor cells. Stem Cell Res (2013) 0.81
Engineering stem cell niches in bioreactors. World J Stem Cells (2013) 0.81
Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1. Nat Methods (2017) 0.81
Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science. Biotechnol J (2015) 0.80
Serial enrichment of spermatogonial stem and progenitor cells (SSCs) in culture for derivation of long-term adult mouse SSC lines. J Vis Exp (2013) 0.79
Concise review: stem cell-based approaches to red blood cell production for transfusion. Stem Cells Transl Med (2013) 0.79
Increasing hematopoietic stem cell yield to develop mice with human immune systems. Biomed Res Int (2013) 0.78
Integrative network analysis of signaling in human CD34(+) hematopoietic progenitor cells by global phosphoproteomic profiling using TiO2 enrichment combined with 2D LC-MS/MS and pathway mapping. Proteomics (2013) 0.78
Improving embryonic stem cell expansion through the combination of perfusion and Bioprocess model design. PLoS One (2013) 0.78
Quality cell therapy manufacturing by design. Nat Biotechnol (2016) 0.78
Inhibiting HDAC for human hematopoietic stem cell expansion. J Clin Invest (2014) 0.77
Distinct signaling programs control human hematopoietic stem cell survival and proliferation. Blood (2016) 0.77
A Multi-Lineage Screen Reveals mTORC1 Inhibition Enhances Human Pluripotent Stem Cell Mesendoderm and Blood Progenitor Production. Stem Cell Reports (2016) 0.76
Proteomic Profiling of Ex Vivo Expanded CD34-Positive Haematopoetic Cells Derived from Umbilical Cord Blood. Stem Cells Int (2013) 0.76
MicroRNA-15b target Sall4 and diminish in vitro UCB-derived HSCs expansion. EXCLI J (2015) 0.76
Challenges and Opportunities to Harnessing the (Hematopoietic) Stem Cell Niche. Curr Stem Cell Rep (2016) 0.76
Optimizing autologous cell grafts to improve stem cell gene therapy. Exp Hematol (2016) 0.76
Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy. Stem Cell Reports (2017) 0.75
Delta-1 provides pleasant stem cell environs. Blood (2014) 0.75
Proportional-Integral-Derivative (PID) Control of Secreted Factors for Blood Stem Cell Culture. PLoS One (2015) 0.75
Research highlights: Highlights from the latest articles in regenerative medicine. Regen Med (2012) 0.75
Dissociation of Survival, Proliferation, and State Control in Human Hematopoietic Stem Cells. Stem Cell Reports (2017) 0.75
Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform. Sci Rep (2016) 0.75
Marrow-inspired matrix cues rapidly affect early fate decisions of hematopoietic stem and progenitor cells. Sci Adv (2017) 0.75
Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application. Sci Rep (2016) 0.75
GM-CSF and IL-4 Fusion Cytokine Induces B Cell-Dependent Hematopoietic Regeneration. Mol Ther (2017) 0.75
Characterization of the growth modulatory activities of osteoblast conditioned media on cord blood progenitor cells. Cytotechnology (2016) 0.75
Predictions for optimal mitigation of paracrine inhibitory signalling in haemopoietic stem cell cultures. Stem Cell Res Ther (2015) 0.75
Concise review: next-generation cell therapies to prevent infections in neutropenic patients. Stem Cells Transl Med (2014) 0.75
In situ hematopoiesis: a regulator of TH2 cytokine-mediated immunity and inflammation at mucosal surfaces. Mucosal Immunol (2015) 0.75
Order Matters: The Order of Somatic Mutations Influences Cancer Evolution. Cold Spring Harb Perspect Med (2017) 0.75
In vitro and in vivo evaluation of cord blood hematopoietic stem and progenitor cells amplified with glycosaminoglycan mimetic. Stem Cell Res Ther (2016) 0.75
Screening platform for cell contact guidance based on inorganic biomaterial micro/nanotopographical gradients. ACS Appl Mater Interfaces (2017) 0.75
Immobilisation of Delta-like 1 ligand for the scalable and controlled manufacture of hematopoietic progenitor cells in a stirred bioreactor. BMC Biotechnol (2017) 0.75
A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A (2004) 44.81
Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U S A (2002) 25.47
Growth factors, matrices, and forces combine and control stem cells. Science (2009) 8.46
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet (2005) 6.91
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science (2010) 5.50
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Mol Cell (2003) 4.25
Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse. Proc Natl Acad Sci U S A (2003) 3.93
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat Cell Biol (2008) 3.44
Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates. PLoS One (2008) 3.08
Niche-mediated control of human embryonic stem cell self-renewal and differentiation. EMBO J (2007) 2.91
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell (2011) 2.89
Brain-wide pathway for waste clearance captured by contrast-enhanced MRI. J Clin Invest (2013) 2.66
Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories. Stem Cells (2008) 2.34
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet (2008) 2.32
c-Myb and p300 regulate hematopoietic stem cell proliferation and differentiation. Dev Cell (2005) 2.30
Resveratrol-induced autophagocytosis in ovarian cancer cells. Cancer Res (2004) 2.20
Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors. Nat Med (2006) 2.16
Falling-edge, variable threshold (FEVT) method for the automated detection of gastric slow wave events in high-resolution serosal electrode recordings. Ann Biomed Eng (2009) 2.09
A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Eng Part A (2012) 1.95
Controlled, scalable embryonic stem cell differentiation culture. Stem Cells (2004) 1.87
Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems. Biotechnol Bioeng (2002) 1.85
In Vivo 3D Digital Atlas Database of the Adult C57BL/6J Mouse Brain by Magnetic Resonance Microscopy. Front Neuroanat (2008) 1.85
The systematic production of cells for cell therapies. Cell Stem Cell (2008) 1.71
Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model. J Invest Dermatol (2008) 1.62
Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor. Biotechnol Bioeng (2009) 1.61
Axon growth and guidance genes identify T-dependent germinal centre B cells. Immunol Cell Biol (2007) 1.60
Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment. Cell Stem Cell (2007) 1.56
Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system. J Biol Chem (2008) 1.54
Positive regulation of Itk PH domain function by soluble IP4. Science (2007) 1.52
Functional immobilization of signaling proteins enables control of stem cell fate. Nat Methods (2008) 1.52
Dynamic interaction networks in a hierarchically organized tissue. Mol Syst Biol (2010) 1.51
STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J Biol Chem (2012) 1.51
Shear-controlled single-step mouse embryonic stem cell expansion and embryoid body-based differentiation. Stem Cells (2005) 1.51
Cell-cell interaction networks regulate blood stem and progenitor cell fate. Mol Syst Biol (2009) 1.49
Hair follicles from alopecia areata patients exhibit alterations in immune privilege-associated gene expression in advance of hair loss. J Invest Dermatol (2010) 1.48
The beneficial effects of the herbal medicine Free and Easy Wanderer Plus (FEWP) and fluoxetine on post-stroke depression. J Altern Complement Med (2008) 1.43
A global assessment of stem cell engineering. Tissue Eng Part A (2014) 1.38
High-throughput generation of hydrogel microbeads with varying elasticity for cell encapsulation. Biomaterials (2010) 1.37
Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell (2009) 1.36
MicroRNA-223 regulates FOXO1 expression and cell proliferation. FEBS Lett (2012) 1.35
Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation. Biomaterials (2010) 1.35
Don't look: growing clonal versus nonclonal neural stem cell colonies. Stem Cells (2008) 1.33
Content-based retrieval of focal liver lesions using bag-of-visual-words representations of single- and multiphase contrast-enhanced CT images. J Digit Imaging (2012) 1.33
Gene expression profile of murine long-term reconstituting vs. short-term reconstituting hematopoietic stem cells. Proc Natl Acad Sci U S A (2005) 1.32
Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance. J Exp Med (2010) 1.32
Autographa californica multiple nucleopolyhedrovirus nucleocapsid assembly is interrupted upon deletion of the 38K gene. J Virol (2006) 1.31
Enabling stem cell therapies through synthetic stem cell-niche engineering. J Clin Invest (2010) 1.31
Design and formulation of functional pluripotent stem cell-derived cardiac microtissues. Proc Natl Acad Sci U S A (2013) 1.29
Development of a perfusion fed bioreactor for embryonic stem cell-derived cardiomyocyte generation: oxygen-mediated enhancement of cardiomyocyte output. Biotechnol Bioeng (2005) 1.28
Understanding cellular networks to improve hematopoietic stem cell expansion cultures. Curr Opin Biotechnol (2006) 1.25
LongSAGE analysis of skeletal muscle at three prenatal stages in Tongcheng and Landrace pigs. Genome Biol (2007) 1.25
High-throughput combinatorial cell co-culture using microfluidics. Integr Biol (Camb) (2011) 1.25
Development of robust hepatitis C virus genotype 4 subgenomic replicons. Gastroenterology (2012) 1.25
Spatial organization of embryonic stem cell responsiveness to autocrine gp130 ligands reveals an autoregulatory stem cell niche. Stem Cells (2006) 1.24
Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures. Nat Methods (2012) 1.23
Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control. PLoS Comput Biol (2007) 1.22
LIF-mediated control of embryonic stem cell self-renewal emerges due to an autoregulatory loop. FASEB J (2007) 1.21
Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity. Proc Natl Acad Sci U S A (2004) 1.20
Automated detection of gastric slow wave events and estimation of propagation velocity vector fields from serosal high-resolution mapping. Conf Proc IEEE Eng Med Biol Soc (2009) 1.19
PERT: a method for expression deconvolution of human blood samples from varied microenvironmental and developmental conditions. PLoS Comput Biol (2012) 1.18
Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway. Hepatology (2008) 1.17
Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphate. Nat Rev Immunol (2010) 1.17
MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways. Am J Physiol Cell Physiol (2004) 1.16
CXCR3/ligands are significantly involved in the tumorigenesis of basal cell carcinomas. Am J Pathol (2010) 1.15
Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism. J Pharmacol Exp Ther (2011) 1.15
Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation. Nat Immunol (2007) 1.13
A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development. Blood (2008) 1.12
Sustained in vitro expansion of bone progenitors is cell density dependent. Stem Cells (2004) 1.12
Geometric control of cardiomyogenic induction in human pluripotent stem cells. Tissue Eng Part A (2011) 1.11
Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue. Proc Natl Acad Sci U S A (2009) 1.10
Ligand/receptor signaling threshold (LIST) model accounts for gp130-mediated embryonic stem cell self-renewal responses to LIF and HIL-6. Stem Cells (2002) 1.09
Dynamic changes in cellular and microenvironmental composition can be controlled to elicit in vitro human hematopoietic stem cell expansion. Exp Hematol (2005) 1.09
Genetic variation and relationships of eighteen Chinese indigenous pig breeds. Genet Sel Evol (2003) 1.08
Data and animal management software for large-scale phenotype screening. Mamm Genome (2006) 1.07
Cocaine increases the intracellular calcium concentration in brain independently of its cerebrovascular effects. J Neurosci (2006) 1.07
An improved strategy for high-level production of TEV protease in Escherichia coli and its purification and characterization. Protein Expr Purif (2006) 1.07
The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain. J Exp Med (2012) 1.07
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation. Blood (2009) 1.07
Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens. PLoS One (2009) 1.03
Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion. Exp Hematol (2003) 1.02
The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells. Biomaterials (2010) 1.01
Genetic relationships among twelve Chinese indigenous goat populations based on microsatellite analysis. Genet Sel Evol (2002) 1.01
The Centre for Modeling Human Disease Gene Trap resource. Nucleic Acids Res (2004) 1.00
Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells. Proc Natl Acad Sci U S A (2012) 1.00
Comparative analysis of human genome assemblies reveals genome-level differences. Genomics (2002) 0.99
Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner. Stem Cells (2008) 0.98
Chemical control of stem cell fate and developmental potential. Angew Chem Int Ed Engl (2011) 0.98
Critical role for Gimap5 in the survival of mouse hematopoietic stem and progenitor cells. J Exp Med (2011) 0.98
Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling. Blood (2013) 0.98
Systematic engineering of 3D pluripotent stem cell niches to guide blood development. Biomaterials (2011) 0.97
Clinically relevant expansion of hematopoietic stem cells with conserved function in a single-use, closed-system bioprocess. Biol Blood Marrow Transplant (2006) 0.96