Published in Nucleic Acids Res on June 27, 2008
Biophysical characterization of DNA binding from single molecule force measurements. Phys Life Rev (2010) 5.81
Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange. Proc Natl Acad Sci U S A (2011) 1.33
Real-time single-molecule observation of rolling-circle DNA replication. Nucleic Acids Res (2009) 1.30
DNA looping by FokI: the impact of twisting and bending rigidity on protein-induced looping dynamics. Nucleic Acids Res (2012) 0.99
Detection of single enzymatic events in rare or single cells using microfluidics. ACS Nano (2011) 0.94
Single-molecule nanometry for biological physics. Rep Prog Phys (2012) 0.93
Efficient preparation of internally modified single-molecule constructs using nicking enzymes. Nucleic Acids Res (2010) 0.92
Tracking of single quantum dot labeled EcoRV sliding along DNA manipulated by double optical tweezers. Biophys J (2009) 0.91
BIOPHYSICAL PROPERTIES OF NUCLEIC ACIDS AT SURFACES RELEVANT TO MICROARRAY PERFORMANCE. Biomater Sci (2014) 0.85
Optical Methods to Study Protein-DNA Interactions in Vitro and in Living Cells at the Single-Molecule Level. Int J Mol Sci (2013) 0.83
Observation of long-range tertiary interactions during ligand binding by the TPP riboswitch aptamer. Elife (2015) 0.83
The diffusion constant of a labeled protein sliding along DNA. Eur Phys J E Soft Matter (2011) 0.81
Mechanisms of small molecule-DNA interactions probed by single-molecule force spectroscopy. Nucleic Acids Res (2016) 0.80
A general approach to visualize protein binding and DNA conformation without protein labelling. Nat Commun (2016) 0.79
A polypeptide-DNA hybrid with selective linking capability applied to single molecule nano-mechanical measurements using optical tweezers. PLoS One (2013) 0.78
The fluorescence properties and binding mechanism of SYTOX green, a bright, low photo-damage DNA intercalating agent. Eur Biophys J (2015) 0.77
High-Resolution "Fleezers": Dual-Trap Optical Tweezers Combined with Single-Molecule Fluorescence Detection. Methods Mol Biol (2017) 0.76
A thiazole coumarin (TC) turn-on fluorescence probe for AT-base pair detection and multipurpose applications in different biological systems. Sci Rep (2014) 0.76
Temperature cycles unravel the dynamics of single biomolecules. Biophys J (2014) 0.75
Precise nanometer localization analysis for individual fluorescent probes. Biophys J (2002) 22.24
Overstretching B-DNA: the elastic response of individual double-stranded and single-stranded DNA molecules. Science (1996) 18.53
The fluorescent toolbox for assessing protein location and function. Science (2006) 14.02
Quantum dot bioconjugates for imaging, labelling and sensing. Nat Mater (2005) 12.97
Direct mechanical measurements of the elasticity of single DNA molecules by using magnetic beads. Science (1992) 9.74
The elasticity of a single supercoiled DNA molecule. Science (1996) 8.58
Optical trapping. Rev Sci Instrum (2004) 7.15
Direct observation of base-pair stepping by RNA polymerase. Nature (2005) 6.29
How do site-specific DNA-binding proteins find their targets? Nucleic Acids Res (2004) 6.17
Total internal reflection fluorescence microscopy in cell biology. Traffic (2001) 4.95
Mechanical processes in biochemistry. Annu Rev Biochem (2004) 4.63
A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA. Proc Natl Acad Sci U S A (2006) 4.60
Alignment and sensitive detection of DNA by a moving interface. Science (1994) 4.18
Single-molecule studies of the effect of template tension on T7 DNA polymerase activity. Nature (2000) 3.98
Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interaction with actin. Cell (1998) 3.79
Single-molecule study of transcriptional pausing and arrest by E. coli RNA polymerase. Science (2000) 3.67
DNA primase acts as a molecular brake in DNA replication. Nature (2006) 3.66
Relaxation of a single DNA molecule observed by optical microscopy. Science (1994) 3.58
Stretching of a single tethered polymer in a uniform flow. Science (1995) 3.48
Measurement of lactose repressor-mediated loop formation and breakdown in single DNA molecules. Science (1995) 3.23
Single-molecule kinetics of lambda exonuclease reveal base dependence and dynamic disorder. Science (2003) 3.22
Recent advances in optical tweezers. Annu Rev Biochem (2008) 3.08
Single-molecule imaging of RNA polymerase-DNA interactions in real time. Biophys J (1999) 3.03
Stretching DNA with a receding meniscus: Experiments and models. Phys Rev Lett (1995) 2.93
Grabbing the cat by the tail: manipulating molecules one by one. Nat Rev Mol Cell Biol (2000) 2.91
Processive translocation and DNA unwinding by individual RecBCD enzyme molecules. Nature (2001) 2.78
A molecular throttle: the recombination hotspot chi controls DNA translocation by the RecBCD helicase. Cell (2003) 2.66
Direct observation of tube-like motion of a single polymer chain. Science (1994) 2.60
Direct observation of individual RecA filaments assembling on single DNA molecules. Nature (2006) 2.55
Long-distance lateral diffusion of human Rad51 on double-stranded DNA. Proc Natl Acad Sci U S A (2006) 2.20
Simultaneous, coincident optical trapping and single-molecule fluorescence. Nat Methods (2004) 2.20
Strategies to improve photostabilities in ultrasensitive fluorescence spectroscopy. J Phys Chem A (2007) 1.99
Interlaced optical force-fluorescence measurements for single molecule biophysics. Biophys J (2006) 1.75
Tying a molecular knot with optical tweezers. Nature (1999) 1.73
A survey of single-molecule techniques in chemical biology. ACS Chem Biol (2007) 1.68
Single-molecule manipulation of double-stranded DNA using optical tweezers: interaction studies of DNA with RecA and YOYO-1. Cytometry (1999) 1.67
Organized arrays of individual DNA molecules tethered to supported lipid bilayers. Langmuir (2006) 1.63
Single- and double-strand photocleavage of DNA by YO, YOYO and TOTO. Nucleic Acids Res (1996) 1.58
RecBCD enzyme switches lead motor subunits in response to chi recognition. Cell (2007) 1.58
Combining optical trapping and single-molecule fluorescence spectroscopy: enhanced photobleaching of fluorophores. J Phys Chem B (2004) 1.55
Single-molecule analysis of 1D diffusion and transcription elongation of T7 RNA polymerase along individual stretched DNA molecules. Nucleic Acids Res (2007) 1.54
Direct visualization of RecBCD movement reveals cotranslocation of the RecD motor after chi recognition. Mol Cell (2005) 1.54
Combined optical trapping and single-molecule fluorescence. J Biol (2003) 1.52
DNA-tension dependence of restriction enzyme activity reveals mechanochemical properties of the reaction pathway. Nucleic Acids Res (2005) 1.48
The dynamics of partially extended single molecules of DNA. Nature (1997) 1.47
Visualizing the assembly of human Rad51 filaments on double-stranded DNA. J Mol Biol (2006) 1.44
Quantifying force-dependent and zero-force DNA intercalation by single-molecule stretching. Nat Methods (2007) 1.44
The interaction of intercalating drugs with nucleic acids. Annu Rev Biophys Bioeng (1981) 1.42
An integrated laser trap/flow control video microscope for the study of single biomolecules. Biophys J (2000) 1.42
Fluorescent human RAD51 reveals multiple nucleation sites and filament segments tightly associated along a single DNA molecule. Structure (2007) 1.41
Real-time imaging of DNA ejection from single phage particles. Curr Biol (2005) 1.40
Dynamics of a tethered polymer in shear flow. Phys Rev Lett (2000) 1.38
Real-time observations of single bacteriophage lambda DNA ejections in vitro. Proc Natl Acad Sci U S A (2007) 1.35
Observation by fluorescence microscopy of transcription on single combed DNA. Proc Natl Acad Sci U S A (2002) 1.30
Visualizing single DNA-bound proteins using DNA as a scanning probe. Nat Methods (2007) 1.24
Laminar flow cells for single-molecule studies of DNA-protein interactions. Nat Methods (2008) 1.21
Single DNA molecule analysis: applications of molecular combing. Brief Funct Genomic Proteomic (2003) 1.13
Dissecting elastic heterogeneity along DNA molecules coated partly with Rad51 using concurrent fluorescence microscopy and optical tweezers. Biophys J (2006) 1.07
Detection of single DNA molecules by multicolor quantum-dot end-labeling. Nucleic Acids Res (2005) 1.04
Honey, I shrunk the DNA: DNA length as a probe for nucleic-acid enzyme activity. Biopolymers (2007) 1.02
A simple DNA stretching method for fluorescence imaging of single DNA molecules. Nucleic Acids Res (2006) 0.93
Optical trap stiffness in the presence and absence of spherical aberrations. Appl Opt (2006) 0.93
Transverse fluctuations of single DNA molecules attached at both extremities to a surface. Phys Rev E Stat Nonlin Soft Matter Phys (2003) 0.86
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks. Nature (2005) 4.63
Bacterial chromatin organization by H-NS protein unravelled using dual DNA manipulation. Nature (2006) 2.41
Counting RAD51 proteins disassembling from nucleoprotein filaments under tension. Nature (2008) 2.21
Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging. Proc Natl Acad Sci U S A (2009) 1.95
The architectural role of nucleoid-associated proteins in the organization of bacterial chromatin: a molecular perspective. J Struct Biol (2006) 1.93
Microtubule cross-linking triggers the directional motility of kinesin-5. J Cell Biol (2008) 1.83
Allosteric inhibition of kinesin-5 modulates its processive directional motility. Nat Chem Biol (2006) 1.81
Using mechanical force to probe the mechanism of pausing and arrest during continuous elongation by Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A (2002) 1.77
High-resolution mass spectrometry of viral assemblies: molecular composition and stability of dimorphic hepatitis B virus capsids. Proc Natl Acad Sci U S A (2008) 1.64
The homotetrameric kinesin-5 KLP61F preferentially crosslinks microtubules into antiparallel orientations. Curr Biol (2008) 1.64
Combining optical trapping and single-molecule fluorescence spectroscopy: enhanced photobleaching of fluorophores. J Phys Chem B (2004) 1.55
Real-time observation of DNA looping dynamics of Type IIE restriction enzymes NaeI and NarI. Nucleic Acids Res (2006) 1.52
Nanocolloidal albumin-IRDye 800CW: a near-infrared fluorescent tracer with optimal retention in the sentinel lymph node. Eur J Nucl Med Mol Imaging (2012) 1.49
DNA-tension dependence of restriction enzyme activity reveals mechanochemical properties of the reaction pathway. Nucleic Acids Res (2005) 1.48
Facilitated diffusion with DNA coiling. Proc Natl Acad Sci U S A (2009) 1.42
Fluorescent human RAD51 reveals multiple nucleation sites and filament segments tightly associated along a single DNA molecule. Structure (2007) 1.41
H-NS promotes looped domain formation in the bacterial chromosome. Curr Biol (2007) 1.39
DNA bridging: a property shared among H-NS-like proteins. J Bacteriol (2005) 1.39
Failure of viral shells. Phys Rev Lett (2006) 1.30
Norwalk virus assembly and stability monitored by mass spectrometry. Mol Cell Proteomics (2010) 1.26
Scaffold expulsion and genome packaging trigger stabilization of herpes simplex virus capsids. Proc Natl Acad Sci U S A (2009) 1.25
Visualizing single DNA-bound proteins using DNA as a scanning probe. Nat Methods (2007) 1.24
Protein-mediated molecular bridging: a key mechanism in biopolymer organization. Biophys J (2009) 1.23
Microtubule-driven multimerization recruits ase1p onto overlapping microtubules. Curr Biol (2008) 1.18
STED nanoscopy combined with optical tweezers reveals protein dynamics on densely covered DNA. Nat Methods (2013) 1.15
Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching using fluorescence microscopy. Proc Natl Acad Sci U S A (2013) 1.14
Elucidating the mechanism behind irreversible deformation of viral capsids. Biophys J (2009) 1.10
Combining optical trapping, fluorescence microscopy and micro-fluidics for single molecule studies of DNA-protein interactions. Phys Chem Chem Phys (2011) 1.10
Combining optical tweezers, single-molecule fluorescence microscopy, and microfluidics for studies of DNA-protein interactions. Methods Enzymol (2010) 1.08
Protein sliding and DNA denaturation are essential for DNA organization by human mitochondrial transcription factor A. Nat Commun (2012) 1.07
Dissecting elastic heterogeneity along DNA molecules coated partly with Rad51 using concurrent fluorescence microscopy and optical tweezers. Biophys J (2006) 1.07
Integrin and defensin modulate the mechanical properties of adenovirus. J Virol (2012) 1.04
Dissecting protein-induced DNA looping dynamics in real time. Nucleic Acids Res (2009) 1.01
Optical tweezers analysis of DNA-protein complexes. Chem Rev (2014) 1.00
Mechanics of bacteriophage maturation. Proc Natl Acad Sci U S A (2012) 1.00
DNA looping by FokI: the impact of twisting and bending rigidity on protein-induced looping dynamics. Nucleic Acids Res (2012) 0.99
DNA synapsis through transient tetramerization triggers cleavage by Ecl18kI restriction enzyme. Nucleic Acids Res (2010) 0.99
The role of the cytoskeleton in sensing changes in gravity by nonspecialized cells. FASEB J (2013) 0.98
Effects of salts on internal DNA pressure and mechanical properties of phage capsids. J Mol Biol (2010) 0.98
Analysis of scanning force microscopy images of protein-induced DNA bending using simulations. Nucleic Acids Res (2005) 0.96
Alba shapes the archaeal genome using a delicate balance of bridging and stiffening the DNA. Nat Commun (2012) 0.96
On the role of H-NS in the organization of bacterial chromatin: from bulk to single molecules and back. Biophys J (2003) 0.95
Discrete fracture patterns of virus shells reveal mechanical building blocks. Proc Natl Acad Sci U S A (2011) 0.94
Sliding sleeves of XRCC4-XLF bridge DNA and connect fragments of broken DNA. Nature (2016) 0.93
Kinesin moving through the spotlight: single-motor fluorescence microscopy with submillisecond time resolution. Biophys J (2007) 0.93
Optical trap stiffness in the presence and absence of spherical aberrations. Appl Opt (2006) 0.93
Jumping mode atomic force microscopy on grana membranes from spinach. J Biol Chem (2011) 0.93
Structural transitions and energy landscape for Cowpea Chlorotic Mottle Virus capsid mechanics from nanomanipulation in vitro and in silico. Biophys J (2013) 0.93
How to quantify protein diffusion in the bacterial membrane. Biopolymers (2011) 0.90
Prestress strengthens the shell of Norwalk virus nanoparticles. Nano Lett (2011) 0.89
89Zr-nanocolloidal albumin-based PET/CT lymphoscintigraphy for sentinel node detection in head and neck cancer: preclinical results. J Nucl Med (2011) 0.89
The effect of monastrol on the processive motility of a dimeric kinesin-5 head/kinesin-1 stalk chimera. J Mol Biol (2010) 0.88
Visualizing the formation and collapse of DNA toroids. Biophys J (2010) 0.87
The expanded octarepeat domain selectively binds prions and disrupts homomeric prion protein interactions. J Biol Chem (2005) 0.87
Imaging and quantification of trans-membrane protein diffusion in living bacteria. Phys Chem Chem Phys (2014) 0.87
DNA looping by FokI: the impact of synapse geometry on loop topology at varied site orientations. Nucleic Acids Res (2012) 0.86
A toolbox for generating single-stranded DNA in optical tweezers experiments. Biopolymers (2013) 0.82
Single-molecule views on homologous recombination. Q Rev Biophys (2013) 0.82
Structure and dynamics of the kinesin-microtubule interaction revealed by fluorescence polarization microscopy. Methods Cell Biol (2010) 0.81
Förster resonance energy transfer and kinesin motor proteins. Chem Soc Rev (2014) 0.81
Kinesin's step dissected with single-motor FRET. Proc Natl Acad Sci U S A (2009) 0.81
Mobility analysis of super-resolved proteins on optically stretched DNA: comparing imaging techniques and parameters. Chemphyschem (2014) 0.81
Sampling protein form and function with the atomic force microscope. Mol Cell Proteomics (2010) 0.80
Alternating-site mechanism of kinesin-1 characterized by single-molecule FRET using fluorescent ATP analogues. Biophys J (2009) 0.80
Effect of temperature on the intrinsic flexibility of DNA and its interaction with architectural proteins. Biochemistry (2014) 0.80
A brief introduction to single-molecule fluorescence methods. Methods Mol Biol (2011) 0.80
Dissociation kinetics of the GroEL-gp31 chaperonin complex studied with Förster resonance energy transfer. Biochemistry (2009) 0.79
Introduction to optical tweezers: background, system designs, and commercial solutions. Methods Mol Biol (2011) 0.79
Novel ways to determine kinesin-1's run length and randomness using fluorescence microscopy. Biophys J (2009) 0.78
Experimental demonstration of an intensity minimum at the focus of a laser beam created by spatial coherence: application to the optical trapping of dielectric particles. Opt Lett (2010) 0.77
Material properties of viral nanocages explored by atomic force microscopy. Methods Mol Biol (2015) 0.76
Corrigendum: Sliding sleeves of XRCC4-XLF bridge DNA and connect fragments of broken DNA. Nature (2017) 0.75
Studying kinesin's enzymatic cycle using a single-motor confocal motility assay, employing Förster resonance energy transfer. Methods Mol Biol (2011) 0.75
[Sample Preparation and Imaging of Single Adenovirus Particle Using Atomic Force Microscopy in Liquid]. Bing Du Xue Bao (2015) 0.75