Published in J Biol Chem on July 30, 2008
Random versus directionally persistent cell migration. Nat Rev Mol Cell Biol (2009) 4.99
The complex world of WNT receptor signalling. Nat Rev Mol Cell Biol (2012) 3.16
Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors. Genes Dev (2010) 2.28
The opposing roles of Wnt-5a in cancer. Br J Cancer (2009) 2.07
Ror receptor tyrosine kinases: orphans no more. Trends Cell Biol (2008) 1.82
Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development. Dev Biol (2012) 1.39
Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis. Proc Natl Acad Sci U S A (2012) 1.36
Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization. Mol Cell Biol (2010) 1.32
Control of hair follicle cell fate by underlying mesenchyme through a CSL-Wnt5a-FoxN1 regulatory axis. Genes Dev (2010) 1.25
Role of WNT-5a in the determination of human mesenchymal stem cells into preadipocytes. J Biol Chem (2009) 1.22
ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour. J Pathol (2012) 1.21
Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt. Pigment Cell Melanoma Res (2009) 1.19
Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements. Development (2011) 1.14
A meckelin-filamin A interaction mediates ciliogenesis. Hum Mol Genet (2011) 1.12
Wnt-5a occludes Abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons. Mol Neurodegener (2010) 1.05
The role of Ryk and Ror receptor tyrosine kinases in Wnt signal transduction. Cold Spring Harb Perspect Biol (2014) 1.03
Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration. PLoS One (2012) 1.01
A switch from canonical to noncanonical Wnt signaling mediates drug resistance in colon cancer cells. PLoS One (2011) 1.01
ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy. Front Oncol (2012) 1.01
Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer. Mol Cancer (2014) 1.00
Ror2 enhances polarity and directional migration of primordial germ cells. PLoS Genet (2011) 0.97
High ROR2 expression in tumor cells and stroma is correlated with poor prognosis in pancreatic ductal adenocarcinoma. Sci Rep (2015) 0.95
Wnt signaling in cancer. Oncogene (2016) 0.95
Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4. J Biol Chem (2010) 0.94
Role of non-canonical Wnt signaling in osteoblast maturation on microstructured titanium surfaces. Acta Biomater (2011) 0.93
Role of Wnt5a-Ror2 signaling in morphogenesis of the metanephric mesenchyme during ureteric budding. Mol Cell Biol (2014) 0.92
Dissection of Wnt5a-Ror2 signaling leading to matrix metalloproteinase (MMP-13) expression. J Biol Chem (2011) 0.92
Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. Diabetes (2014) 0.92
Prickle1 is necessary for the caudal migration of murine facial branchiomotor neurons. Cell Tissue Res (2014) 0.88
Both canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres. PLoS One (2014) 0.88
Extra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders. Genes Cells (2013) 0.87
Expression of Wnt signaling components during Xenopus pronephros development. PLoS One (2011) 0.87
Cytoskeletal proteins in cortical development and disease: actin associated proteins in periventricular heterotopia. Front Cell Neurosci (2015) 0.86
Effect of the WWOX gene on the regulation of the cell cycle and apoptosis in human ovarian cancer stem cells. Mol Med Rep (2015) 0.86
WNT-5A: signaling and functions in health and disease. Cell Mol Life Sci (2015) 0.86
Protein Depalmitoylation Is Induced by Wnt5a and Promotes Polarized Cell Behavior. J Biol Chem (2015) 0.86
Challenging role of Wnt5a and its signaling pathway in cancer metastasis (Review). Exp Ther Med (2014) 0.86
Adapter protein SH2B1beta binds filamin A to regulate prolactin-dependent cytoskeletal reorganization and cell motility. Mol Endocrinol (2011) 0.85
Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion. Oncotarget (2015) 0.83
The regulation of osteoclast differentiation by Wnt signals. Bonekey Rep (2015) 0.82
Cell polarity: The missing link in skeletal morphogenesis? Organogenesis (2011) 0.82
The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway. J Biol Chem (2015) 0.81
Wnt5a inhibits the proliferation and melanogenesis of melanocytes. Int J Med Sci (2013) 0.79
Filamin B: a scaffold for interferon signalling. EMBO Rep (2009) 0.79
C-Jun N-terminal kinase (JNK) mediates Wnt5a-induced cell motility dependent or independent of RhoA pathway in human dental papilla cells. PLoS One (2013) 0.79
Polarizing intestinal epithelial cells electrically through Ror2. J Cell Sci (2014) 0.79
ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration. BMC Cancer (2016) 0.78
Binding of pro-prion to filamin A: by design or an unfortunate blunder. Oncogene (2010) 0.78
Drug-induced regeneration in adult mice. Sci Transl Med (2015) 0.78
Receptor tyrosine kinase signaling: regulating neural crest development one phosphate at a time. Curr Top Dev Biol (2015) 0.77
A PTK7/Ror2 Co-Receptor Complex Affects Xenopus Neural Crest Migration. PLoS One (2015) 0.77
Monocyte-derived dendritic cells from HLA-B27+ axial spondyloarthritis (SpA) patients display altered functional capacity and deregulated gene expression. Arthritis Res Ther (2014) 0.77
Generation of intestinal surface: an absorbing tale. Development (2016) 0.77
Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains. PLoS One (2014) 0.77
Aberrant regulation of Wnt signaling in hepatocellular carcinoma. World J Gastroenterol (2016) 0.76
Tyrosine phosphorylation-mediated signaling pathways in dictyostelium. J Signal Transduct (2011) 0.76
Biological functions of macrophage-derived Wnt5a, and its roles in human diseases. Oncotarget (2016) 0.75
DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly. Dev Biol (2015) 0.75
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness. Sci Rep (2017) 0.75
Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity-signaling pathway. Mol Biol Cell (2016) 0.75
Validation of specificity of antibodies for immunohistochemistry: the case of ROR2. Virchows Arch (2016) 0.75
Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer. Sci Rep (2017) 0.75
Ror2 Signaling and Its Relevance in Breast Cancer Progression. Front Oncol (2017) 0.75
The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway. Genes Cells (2003) 4.11
Retracted A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation. Nat Cell Biol (2007) 3.97
Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis. Nat Med (2012) 3.46
Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2. Dev Cell (2011) 3.12
Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev Cell (2008) 2.89
Retracted Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell (2009) 2.48
Wip1 phosphatase modulates ATM-dependent signaling pathways. Mol Cell (2006) 2.39
A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia. J Cell Biol (2004) 2.14
The role of leptin in the development of the cerebral cortex in mouse embryos. Endocrinology (2005) 1.89
Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development. Development (2008) 1.74
Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration. J Cell Biol (2006) 1.67
Ror2 expression in squamous cell carcinoma and epithelial dysplasia of the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 1.67
Pulmonary hypertension in adult Alk1 heterozygous mice due to oxidative stress. Cardiovasc Res (2011) 1.59
Ror-family receptor tyrosine kinases in noncanonical Wnt signaling: their implications in developmental morphogenesis and human diseases. Dev Dyn (2010) 1.58
MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration. EMBO J (2006) 1.57
Cell/tissue-tropic functions of Wnt5a signaling in normal and cancer cells. Trends Cell Biol (2010) 1.56
Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. J Biol Chem (2009) 1.52
Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex. J Biol Chem (2004) 1.46
Sprouty2 and Sprouty4 are essential for embryonic morphogenesis and regulation of FGF signaling. Biochem Biophys Res Commun (2006) 1.41
Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia development by concerted actions of BMP signaling [corrected]. Development (2003) 1.38
Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization. Mol Cell Biol (2010) 1.32
Critical role of Wnt5a-Ror2 signaling in motility and invasiveness of carcinoma cells following Snail-mediated epithelial-mesenchymal transition. Genes Cells (2011) 1.30
Expression and function of the Ror-family receptor tyrosine kinases during development: lessons from genetic analyses of nematodes, mice, and humans. J Recept Signal Transduct Res (2003) 1.23
The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon. J Biol Chem (2004) 1.22
ABL1 regulates spindle orientation in adherent cells and mammalian skin. Nat Commun (2012) 1.20
Wnt5a modulates glycogen synthase kinase 3 to induce phosphorylation of receptor tyrosine kinase Ror2. Genes Cells (2007) 1.19
Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2. BMC Mol Biol (2008) 1.18
Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome. Dev Dyn (2004) 1.18
Involvement of NLK and Sox11 in neural induction in Xenopus development. Genes Cells (2002) 1.16
Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase. J Biol Chem (2008) 1.11
Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1. J Biol Chem (2006) 1.10
The mouse ortholog of EFHC1 implicated in juvenile myoclonic epilepsy is an axonemal protein widely conserved among organisms with motile cilia and flagella. FEBS Lett (2005) 1.09
Ror2 is required for midgut elongation during mouse development. Dev Dyn (2010) 1.06
Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2. Genes Cells (2004) 1.03
The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution. J Biol Chem (2003) 0.98
Importin alpha/beta mediates nuclear transport of a mammalian circadian clock component, mCRY2, together with mPER2, through a bipartite nuclear localization signal. J Biol Chem (2005) 0.97
Neuronal lineage-specific induction of phospholipase Cepsilon expression in the developing mouse brain. Eur J Neurosci (2003) 0.96
Hypoxia-inducible factor-1alpha induces cell cycle arrest of endothelial cells. Genes Cells (2002) 0.96
A determination of bite force in northern Japanese children. Eur J Orthod (2005) 0.95
Highly cooperative dependence of sarco/endoplasmic reticulum calcium ATPase SERCA2a pump activity on cytosolic calcium in living cells. J Biol Chem (2011) 0.95
Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded. Dev Dyn (2010) 0.95
L-ornithine derived polyamines in cystic fibrosis airways. PLoS One (2012) 0.95
Inositol 1,4,5-trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist Trypanosoma cruzi. Mol Microbiol (2013) 0.93
Receptor-selective diffusion barrier enhances sensitivity of astrocytic processes to metabotropic glutamate receptor stimulation. Sci Signal (2012) 0.93
Noncanonical Wnt signaling mediates androgen-dependent tumor growth in a mouse model of prostate cancer. Proc Natl Acad Sci U S A (2011) 0.92
Dissection of Wnt5a-Ror2 signaling leading to matrix metalloproteinase (MMP-13) expression. J Biol Chem (2011) 0.92
Alkaloidal components in the poisonous plant, Ipomoea carnea (Convolvulaceae). J Agric Food Chem (2003) 0.89
CaBP1, a neuronal Ca2+ sensor protein, inhibits inositol trisphosphate receptors by clamping intersubunit interactions. Proc Natl Acad Sci U S A (2013) 0.89
Intracellular HMGB1 transactivates the human IL1B gene promoter through association with an Ets transcription factor PU.1. Eur J Haematol (2008) 0.87
Ryanodine receptor calcium release channels: lessons from structure-function studies. FEBS J (2013) 0.86
Caspase-mediated cleavage and activation of LIM-kinase 1 and its role in apoptotic membrane blebbing. Genes Cells (2004) 0.85
Mechanistic basis of bell-shaped dependence of inositol 1,4,5-trisphosphate receptor gating on cytosolic calcium. Proc Natl Acad Sci U S A (2011) 0.85
Activation of Wnt5a-Ror2 signaling associated with epithelial-to-mesenchymal transition of tubular epithelial cells during renal fibrosis. Genes Cells (2013) 0.85
Ror family receptor tyrosine kinases regulate the maintenance of neural progenitor cells in the developing neocortex. J Cell Sci (2012) 0.85
Membrane-bound form of fractalkine induces IFN-gamma production by NK cells. Eur J Immunol (2003) 0.83
Themes and variations in ER/SR calcium release channels: structure and function. Physiology (Bethesda) (2012) 0.83
H-Ras/mitogen-activated protein kinase pathway inhibits integrin-mediated adhesion and induces apoptosis in osteoblasts. J Biol Chem (2002) 0.81
Pulmonary hypertension in the newborn GTP cyclohydrolase I-deficient mouse. Free Radic Biol Med (2011) 0.80
Molecular characterization of the 5'-UTR of retinal dystrophin reveals a cryptic intron that regulates translational activity. Mol Vis (2010) 0.80
Role for adapter proteins in costimulatory signals of CD2 and IL-2 on NK cell activation. Mol Immunol (2002) 0.80
Neurotrophic effect of gonadotropin-releasing hormone on neurite extension and neuronal migration of embryonic gonadotropin-releasing hormone neurons in chick olfactory nerve bundle culture. J Neurosci Res (2009) 0.80
Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation. Biochem J (2010) 0.80
Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling. Genes Cells (2007) 0.79
Sustained therapeutic hypercapnia attenuates pulmonary arterial Rho-kinase activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats. Am J Physiol Heart Circ Physiol (2012) 0.79
Analysis of Wnt/planar cell polarity pathway in cultured cells. Methods Mol Biol (2012) 0.78
Regulation of the cell proliferation and migration as extra-pituitary functions of GnRH. Gen Comp Endocrinol (2012) 0.78
Identification of N-acetyl Proline-Glycine-Proline (acPGP) in human serum of adults and newborns by liquid chromatography-tandem mass spectrometry. Clin Chim Acta (2009) 0.78
Molecular cloning and characterization of a gonadotropin-releasing hormone receptor in the guinea pig, Cavia porcellus. Gen Comp Endocrinol (2004) 0.77
[Relationship between abnormalities of genes involved in DNA damage responses and malignant tumors/autoimmune diseases]. Nihon Rinsho Meneki Gakkai Kaishi (2006) 0.77
Tetrahydrobiopterin deficiency induces gastroparesis in newborn mice. Am J Physiol Gastrointest Liver Physiol (2013) 0.77
Two different effects of transcranial magnetic stimulation to the human motor cortex during the pre-movement period. Neurosci Res (2004) 0.77
Constitutive association of MyD88 to IRAK in HTLV-I-transformed T cells. Exp Hematol (2007) 0.77
Validity of screening methods for periodontitis using salivary hemoglobin level and self-report questionnaires in people with disabilities. J Periodontol (2015) 0.77
[Regulation of cellular responses by non-canonical Wnt signaling]. Clin Calcium (2013) 0.76
Prolonging in utero-like oxygenation after birth diminishes oxidative stress in the lung and brain of mice pups. Redox Biol (2013) 0.76
Critical role of Frizzled1 in age-related alterations of Wnt/β-catenin signal in myogenic cells during differentiation. Genes Cells (2014) 0.76
Structure-activity relationships of flavonoids as potential inhibitors of glycogen phosphorylase. J Agric Food Chem (2008) 0.76
Acute gastritis associated with invading Helicobacter heilmannii organisms from a previously homeless cat. J Clin Gastroenterol (2008) 0.75
Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B. J Physiol Sci (2011) 0.75
Relationship between electrical resistance measurements and microradiographic variables during remineralization of softened enamel lesions. Caries Res (2004) 0.75
Constitutive tyrosine and serine phosphorylation of STAT4 in T-cells transformed with HTLV-I. Genes Cells (2005) 0.75
[A case of breast adenocarcinoma changed to squamous cell carcinoma after neoadjuvant chemotherapy]. Gan To Kagaku Ryoho (2012) 0.75
Physical interactions of Dmnk with Orb: implications in the regulated localization of Orb by Dmnk during oogenesis and embryogenesis. Biochem Biophys Res Commun (2002) 0.75
Reliability of Total Bilirubin Measurements in Whole Blood from Preterm Neonates Using a Blood Gas Analyzer. Clin Lab (2016) 0.75
Speech feature extraction method using subband-based periodicity and nonperiodicity decomposition. J Acoust Soc Am (2006) 0.75