Published in Cancer Res on August 01, 2008
p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci U S A (2009) 5.05
Genetic prognostic and predictive markers in colorectal cancer. Nat Rev Cancer (2009) 3.99
MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1. Cancer Res (2009) 2.64
miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer (2010) 2.51
MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol Cancer (2009) 2.45
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. BMC Cancer (2009) 2.32
Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer. BMC Cancer (2009) 2.27
MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer. BMC Cancer (2010) 2.10
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol (2011) 1.98
Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis. Cancer Res (2010) 1.88
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MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. Nucleic Acids Res (2011) 1.77
Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology (2009) 1.76
Aberrant expression of microRNAs in bladder cancer. Nat Rev Urol (2013) 1.74
miRNA expression in colon polyps provides evidence for a multihit model of colon cancer. PLoS One (2011) 1.72
miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc. J Exp Clin Cancer Res (2010) 1.67
MicroRNA-145 targets YES and STAT1 in colon cancer cells. PLoS One (2010) 1.64
Epigenetics of colorectal cancer. Gastroenterology (2012) 1.60
The functional significance of microRNA-145 in prostate cancer. Br J Cancer (2010) 1.48
New strategies in hepatocellular carcinoma: genomic prognostic markers. Clin Cancer Res (2010) 1.46
An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell (2014) 1.44
The role of microRNAs in colorectal cancer. Cancer J (2012) 1.44
MicroRNAs: critical mediators of differentiation, development and disease. Swiss Med Wkly (2009) 1.43
MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1 (RASA1). J Biol Chem (2013) 1.43
MicroRNA signature analysis in colorectal cancer: identification of expression profiles in stage II tumors associated with aggressive disease. Int J Colorectal Dis (2011) 1.43
An evaluation and replication of miRNAs with disease stage and colorectal cancer-specific mortality. Int J Cancer (2014) 1.42
n-3 Polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon. Carcinogenesis (2009) 1.41
A small noncoding RNA signature found in exosomes of GBM patient serum as a diagnostic tool. Neuro Oncol (2014) 1.40
Plasma miR-601 and miR-760 are novel biomarkers for the early detection of colorectal cancer. PLoS One (2012) 1.36
Expression and function of the insulin receptor substrate proteins in cancer. Cell Commun Signal (2009) 1.35
Identification and functional screening of microRNAs highly deregulated in colorectal cancer. J Cell Mol Med (2012) 1.34
Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene Friend leukemia virus integration 1 gene. Cancer (2010) 1.34
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miR-145-mediated suppression of cell growth, invasion and metastasis. Am J Transl Res (2010) 1.29
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The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer. PLoS One (2012) 1.26
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MicroRNA profiles discriminate among colon cancer metastasis. PLoS One (2014) 1.22
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The impact of microRNAs on colorectal cancer. Virchows Arch (2009) 1.20
Negative regulation of miR-145 by C/EBP-β through the Akt pathway in cancer cells. Nucleic Acids Res (2012) 1.19
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MicroRNA-145 in vascular smooth muscle cell biology: a new therapeutic target for vascular disease. Cell Cycle (2009) 1.19
MicroRNAs in inflammatory bowel disease. Inflamm Bowel Dis (2011) 1.19
Alterations of microRNAs contribute to colon carcinogenesis. Semin Oncol (2011) 1.19
EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators. Mol Cancer Res (2011) 1.18
Differential expression of microRNAs in tumors from chronically inflamed or genetic (APC(Min/+)) models of colon cancer. PLoS One (2011) 1.16
The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer. Br J Cancer (2011) 1.16
MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma. Orphanet J Rare Dis (2013) 1.13
Recent insights into the pathogenesis of colorectal cancer. Curr Opin Gastroenterol (2010) 1.13
MiR-145, a new regulator of the DNA fragmentation factor-45 (DFF45)-mediated apoptotic network. Mol Cancer (2010) 1.09
The role of microRNAs in ovarian cancer initiation and progression. J Cell Mol Med (2010) 1.08
MicroRNA-145: a potent tumour suppressor that regulates multiple cellular pathways. J Cell Mol Med (2014) 1.08
Deep sequencing of RNA from three different extracellular vesicle (EV) subtypes released from the human LIM1863 colon cancer cell line uncovers distinct miRNA-enrichment signatures. PLoS One (2014) 1.07
MicroRNA-137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neck. Cancer (2010) 1.07
Role of miR-19b and its target mRNAs in 5-fluorouracil resistance in colon cancer cells. J Gastroenterol (2012) 1.07
MicroRNA dysregulation as a prognostic biomarker in colorectal cancer. Cancer Manag Res (2014) 1.05
The Diagnostic and Prognostic Role of microRNA in Colorectal Cancer - a Comprehensive review. J Cancer (2013) 1.05
Future directions for the early detection of colorectal cancer recurrence. J Cancer (2014) 1.05
miR-320c regulates gemcitabine-resistance in pancreatic cancer via SMARCC1. Br J Cancer (2013) 1.05
In situ hybridization is a necessary experimental complement to microRNA (miRNA) expression profiling in the human brain. Neurosci Lett (2009) 1.04
Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer. Oncotarget (2016) 1.04
1,25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498. J Biol Chem (2012) 1.03
Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas. Virchows Arch (2011) 1.03
Identification of serum microRNA profiles in colon cancer. Br J Cancer (2013) 1.02
Role of microRNAs in the immune system, inflammation and cancer. World J Gastroenterol (2013) 1.02
DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma. World J Gastroenterol (2014) 0.99
MicroRNA-217 functions as a tumour suppressor gene and correlates with cell resistance to cisplatin in lung cancer. Mol Cells (2014) 0.98
Up-regulation of microRNA-145 associates with lymph node metastasis in colorectal cancer. PLoS One (2014) 0.98
Specific protein and miRNA patterns characterise tumour-associated fibroblasts in bladder cancer. J Cancer Res Clin Oncol (2010) 0.98
The predictive value of microRNA-126 in relation to first line treatment with capecitabine and oxaliplatin in patients with metastatic colorectal cancer. BMC Cancer (2012) 0.98
Epigenetics Offer New Horizons for Colorectal Cancer Prevention. Curr Colorectal Cancer Rep (2012) 0.97
MicroRNA-320c inhibits tumorous behaviors of bladder cancer by targeting Cyclin-dependent kinase 6. J Exp Clin Cancer Res (2014) 0.97
Integrating contextual miRNA and protein signatures for diagnostic and treatment decisions in cancer. Expert Rev Mol Diagn (2011) 0.97
Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems. FASEB J (2012) 0.97
MicroRNA-320a sensitizes tamoxifen-resistant breast cancer cells to tamoxifen by targeting ARPP-19 and ERRγ. Sci Rep (2015) 0.96
Identification of pathogenesis-related microRNAs in hepatocellular carcinoma by expression profiling. Oncol Lett (2012) 0.95
Epigenetic changes in colorectal cancer. Chin J Cancer (2011) 0.94
MicroRNA-21 is involved in ionizing radiation-promoted liver carcinogenesis. Int J Clin Exp Med (2010) 0.93
MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial. Br J Cancer (2013) 0.93
GNAI1 Suppresses Tumor Cell Migration and Invasion and is Post-Transcriptionally Regulated by Mir-320a/c/d in Hepatocellular Carcinoma. Cancer Biol Med (2012) 0.92
Tumor suppressors miR-143 and miR-145 and predicted target proteins API5, ERK5, K-RAS, and IRS-1 are differentially expressed in proximal and distal colon. Am J Physiol Gastrointest Liver Physiol (2014) 0.92
MicroRNAs as Novel Biomarkers in Colorectal Cancer. Front Genet (2012) 0.92
Recurrence of early stage colon cancer predicted by expression pattern of circulating microRNAs. PLoS One (2014) 0.92
Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis. Genes Dev (2014) 0.91
KRAS-dependent sorting of miRNA to exosomes. Elife (2015) 0.91
The functional significance of microRNA-29c in patients with colorectal cancer: a potential circulating biomarker for predicting early relapse. PLoS One (2013) 0.91
Analysis of differential miRNA expression in primary tumor and stroma of colorectal cancer patients. Biomed Res Int (2014) 0.91
Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer. PLoS One (2014) 0.90
Integration of mRNA expression profile, copy number alterations, and microRNA expression levels in breast cancer to improve grade definition. PLoS One (2014) 0.90
The Role of miRNAs as Key Regulators in the Neoplastic Microenvironment. Mol Biol Int (2011) 0.90
Differential expression of miRNAs in colon cancer between African and Caucasian Americans: implications for cancer racial health disparities. Int J Oncol (2014) 0.90
Cellular microRNAs 498 and 320d regulate herpes simplex virus 1 induction of Kaposi's sarcoma-associated herpesvirus lytic replication by targeting RTA. PLoS One (2013) 0.90
miRNAs as biomarkers in colorectal cancer diagnosis and prognosis. Bioanalysis (2010) 0.89
MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2. Oncotarget (2016) 0.89
MicroRNAs in colorectal cancer: role in metastasis and clinical perspectives. World J Gastroenterol (2014) 0.89
MicroRNA manipulation in colorectal cancer cells: from laboratory to clinical application. J Transl Med (2012) 0.88
Tumor-suppressive microRNA-145 induces growth arrest by targeting SENP1 in human prostate cancer cells. Cancer Sci (2015) 0.88
MiRNAs and LincRNAs: Could they be considered as biomarkers in colorectal cancer? Int J Mol Sci (2012) 0.87
MicroRNA expression in zebrafish embryonic development. Science (2005) 15.52
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature (2006) 11.76
LNA-mediated microRNA silencing in non-human primates. Nature (2008) 11.45
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science (2009) 10.30
Treatment of HCV infection by targeting microRNA. N Engl J Med (2013) 9.91
In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat Methods (2006) 6.67
Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res (2007) 5.67
Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer. Cancer Res (2007) 5.25
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci U S A (2008) 5.24
RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain. RNA (2005) 4.91
Silencing of microRNA families by seed-targeting tiny LNAs. Nat Genet (2011) 4.81
Recharacterization of ancient DNA miscoding lesions: insights in the era of sequencing-by-synthesis. Nucleic Acids Res (2006) 4.70
Diverse plant and animal genetic records from Holocene and Pleistocene sediments. Science (2003) 4.48
Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes. Nucleic Acids Res (2004) 3.97
Identifying distinct classes of bladder carcinoma using microarrays. Nat Genet (2002) 3.82
Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification. Cancer Res (2004) 3.76
Subnets of scale-free networks are not scale-free: sampling properties of networks. Proc Natl Acad Sci U S A (2005) 3.75
Estimating the size of the human interactome. Proc Natl Acad Sci U S A (2008) 3.66
p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest. Cancer Res (2008) 3.58
LNA-modified oligonucleotides mediate specific inhibition of microRNA function. Gene (2006) 3.49
Monitoring endangered freshwater biodiversity using environmental DNA. Mol Ecol (2011) 3.45
A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat Cell Biol (2009) 3.44
MicroRNA expression in the adult mouse central nervous system. RNA (2008) 3.12
Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer. Clin Cancer Res (2009) 3.08
Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. J Clin Invest (2010) 3.04
Molecular staging for survival prediction of colorectal cancer patients. J Clin Oncol (2005) 2.88
MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. J Clin Invest (2010) 2.87
Detection of microRNAs in frozen tissue sections by fluorescence in situ hybridization using locked nucleic acid probes and tyramide signal amplification. Nat Protoc (2007) 2.80
Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro. Cancer Res (2009) 2.80
miR-200b mediates post-transcriptional repression of ZFHX1B. RNA (2007) 2.67
Identification of endogenous retroviral reading frames in the human genome. Retrovirology (2004) 2.58
Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer. Int J Cancer (2011) 2.49
Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts. Blood (2002) 2.48
Sensitive digital quantification of DNA methylation in clinical samples. Nat Biotechnol (2009) 2.34
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. J Clin Invest (2011) 2.30
Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery (2009) 2.29
Evidence-based medicine: the time has come to set standards for staging. J Pathol (2010) 2.26
Alternative splicing in colon, bladder, and prostate cancer identified by exon array analysis. Mol Cell Proteomics (2008) 2.24
Assessing the fidelity of ancient DNA sequences amplified from nuclear genes. Genetics (2005) 2.21
Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet (2011) 2.21
Uncovering growth-suppressive MicroRNAs in lung cancer. Clin Cancer Res (2009) 2.19
Ulcerative colitis: female fecundity before diagnosis, during disease, and after surgery compared with a population sample. Gastroenterology (2002) 2.17
Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase. Cancer Cell (2013) 2.09
Cause-specific colostomy rates after radiotherapy for anal cancer: a Danish multicentre cohort study. J Clin Oncol (2011) 2.06
MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo. Proc Natl Acad Sci U S A (2011) 2.05
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Inhibition of microRNA function by antimiR oligonucleotides. Silence (2012) 2.02
MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proc Natl Acad Sci U S A (2009) 2.00
Frequent occurrence of uniparental disomy in colorectal cancer. Carcinogenesis (2006) 1.99
Gene expression in colorectal cancer. Cancer Res (2002) 1.98
Model criticism based on likelihood-free inference, with an application to protein network evolution. Proc Natl Acad Sci U S A (2009) 1.89
Emmprin and survivin predict response and survival following cisplatin-containing chemotherapy in patients with advanced bladder cancer. Clin Cancer Res (2007) 1.87
Next-generation stool DNA test accurately detects colorectal cancer and large adenomas. Gastroenterology (2011) 1.86
The utility of LNA in microRNA-based cancer diagnostics and therapeutics. Semin Cancer Biol (2008) 1.84
Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration. Hum Mol Genet (2010) 1.83
Sacral nerve stimulation for intractable constipation. Gut (2010) 1.82
A randomized, controlled trial of transanal irrigation versus conservative bowel management in spinal cord-injured patients. Gastroenterology (2006) 1.79
Perianal injectable bulking agents as treatment for faecal incontinence in adults. Cochrane Database Syst Rev (2013) 1.72
Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF. Nucleic Acids Res (2009) 1.72
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function. Proc Natl Acad Sci U S A (2012) 1.72
Characteristics and survival of interval and sporadic colorectal cancer patients: a nationwide population-based cohort study. Am J Gastroenterol (2013) 1.71
Long-term persistence of bacterial DNA. Curr Biol (2004) 1.70
Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells. J Cell Biol (2002) 1.67
SOX4 expression in bladder carcinoma: clinical aspects and in vitro functional characterization. Cancer Res (2006) 1.66
Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas. Int J Cancer (2011) 1.65
A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays. BMC Bioinformatics (2007) 1.65
Low anterior resection syndrome and quality of life: an international multicenter study. Dis Colon Rectum (2014) 1.63
Danish national guidelines for treatment of diverticular disease. Dan Med J (2012) 1.63
Full genome gene expression analysis of the heat stress response in Drosophila melanogaster. Cell Stress Chaperones (2005) 1.63
Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells. Diabetes (2003) 1.63
OligoDesign: Optimal design of LNA (locked nucleic acid) oligonucleotide capture probes for gene expression profiling. Nucleic Acids Res (2003) 1.59
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation. J Biol Chem (2010) 1.49
MicroRNA profiles of prostate carcinoma detected by multiplatform microRNA screening. Int J Cancer (2011) 1.47
Comprehensive genome methylation analysis in bladder cancer: identification and validation of novel methylated genes and application of these as urinary tumor markers. Clin Cancer Res (2011) 1.46
Predicting the Risk of Bowel-Related Quality-of-Life Impairment After Restorative Resection for Rectal Cancer: A Multicenter Cross-Sectional Study. Dis Colon Rectum (2016) 1.45
Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumors. Clin Cancer Res (2010) 1.44
Spatio-temporal accumulation of microRNAs is highly coordinated in developing plant tissues. Plant J (2006) 1.44
DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers. Clin Cancer Res (2008) 1.44
Pep-13, a plant defense-inducing pathogen-associated pattern from Phytophthora transglutaminases. EMBO J (2002) 1.44
Crosslinks rather than strand breaks determine access to ancient DNA sequences from frozen sediments. Genetics (2006) 1.44
LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas. Blood (2012) 1.42