Anne U Jackson

Author PubWeight™ 421.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007 43.16
2 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008 35.06
3 Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008 25.83
4 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
5 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2008 22.35
6 Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2008 20.66
7 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
8 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
9 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010 16.96
10 Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet 2008 16.25
11 Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008 15.94
12 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
13 Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet 2009 12.44
14 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012 11.09
15 Variants in MTNR1B influence fasting glucose levels. Nat Genet 2008 10.85
16 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
17 Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet 2008 7.31
18 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
19 The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet 2012 6.15
20 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
21 Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet 2008 4.84
22 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
23 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet 2012 4.37
24 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 2014 4.13
25 Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes 2010 4.07
26 Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet 2011 3.56
27 Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest 2008 3.51
28 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
29 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
30 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
31 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
32 Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 2013 2.83
33 FTO genotype is associated with phenotypic variability of body mass index. Nature 2012 2.77
34 Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes 2006 2.58
35 Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion. Nat Genet 2012 2.55
36 A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes 2004 2.46
37 Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes 2010 2.44
38 Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. Diabetes 2004 2.43
39 High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools. Proc Natl Acad Sci U S A 2002 2.32
40 Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes 2011 2.21
41 Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes 2006 2.03
42 Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes 2008 2.01
43 Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men. Diabetes 2009 1.87
44 Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. Diabetes 2007 1.74
45 Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database. Genet Epidemiol 2006 1.74
46 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
47 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
48 SNP Function Portal: a web database for exploring the function implication of SNP alleles. Bioinformatics 2006 1.69
49 Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet 2009 1.61
50 Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet 2013 1.57
51 Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes 2013 1.25
52 Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns. Hum Genet 2005 1.18
53 The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects. Hum Mol Genet 2009 1.09
54 Estimating hepatic glucokinase activity using a simple model of lactate kinetics. Diabetes Care 2012 1.07
55 Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men. Diabetes 2011 0.99
56 Identification of quantitative trait loci for susceptibility to mouse adenovirus type 1. J Virol 2005 0.95
57 Coordinated genetic control of neoplastic and nonneoplastic diseases in mice. J Gerontol A Biol Sci Med Sci 2002 0.93
58 Genome-wide meta-analysis of common variant differences between men and women. Hum Mol Genet 2012 0.88
59 No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. Diabetes 2012 0.86
60 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
61 ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition. medRxiv 2020 0.75
62 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75