Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
|
Science
|
2007
|
43.16
|
2
|
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
Nat Genet
|
2008
|
35.06
|
3
|
Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
|
Nat Genet
|
2008
|
25.83
|
4
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
5
|
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
|
Nat Genet
|
2008
|
22.35
|
6
|
Common variants at 30 loci contribute to polygenic dyslipidemia.
|
Nat Genet
|
2008
|
20.66
|
7
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
8
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
9
|
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
Nat Genet
|
2010
|
16.96
|
10
|
Identification of ten loci associated with height highlights new biological pathways in human growth.
|
Nat Genet
|
2008
|
16.25
|
11
|
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
|
Nat Genet
|
2008
|
15.94
|
12
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
13
|
Genome-wide association study identifies eight loci associated with blood pressure.
|
Nat Genet
|
2009
|
12.44
|
14
|
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
|
Nat Genet
|
2012
|
11.09
|
15
|
Variants in MTNR1B influence fasting glucose levels.
|
Nat Genet
|
2008
|
10.85
|
16
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
17
|
Common variants in the GDF5-UQCC region are associated with variation in human height.
|
Nat Genet
|
2008
|
7.31
|
18
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
19
|
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits.
|
PLoS Genet
|
2012
|
6.15
|
20
|
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
|
PLoS Genet
|
2009
|
5.81
|
21
|
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.
|
Nat Genet
|
2008
|
4.84
|
22
|
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
Nat Genet
|
2012
|
4.73
|
23
|
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|
Nat Genet
|
2012
|
4.37
|
24
|
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
|
Nat Genet
|
2014
|
4.13
|
25
|
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.
|
Diabetes
|
2010
|
4.07
|
26
|
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability.
|
PLoS Genet
|
2011
|
3.56
|
27
|
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.
|
J Clin Invest
|
2008
|
3.51
|
28
|
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
|
Nat Genet
|
2011
|
3.40
|
29
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
30
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
31
|
Common variants associated with plasma triglycerides and risk for coronary artery disease.
|
Nat Genet
|
2013
|
2.92
|
32
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
33
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
34
|
Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample.
|
Diabetes
|
2006
|
2.58
|
35
|
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion.
|
Nat Genet
|
2012
|
2.55
|
36
|
A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14.
|
Diabetes
|
2004
|
2.46
|
37
|
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.
|
Diabetes
|
2010
|
2.44
|
38
|
Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes.
|
Diabetes
|
2004
|
2.43
|
39
|
High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools.
|
Proc Natl Acad Sci U S A
|
2002
|
2.32
|
40
|
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
|
Diabetes
|
2011
|
2.21
|
41
|
Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns.
|
Diabetes
|
2006
|
2.03
|
42
|
Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes.
|
Diabetes
|
2008
|
2.01
|
43
|
Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.
|
Diabetes
|
2009
|
1.87
|
44
|
Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes.
|
Diabetes
|
2007
|
1.74
|
45
|
Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database.
|
Genet Epidemiol
|
2006
|
1.74
|
46
|
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
|
Nat Genet
|
2013
|
1.72
|
47
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
48
|
SNP Function Portal: a web database for exploring the function implication of SNP alleles.
|
Bioinformatics
|
2006
|
1.69
|
49
|
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.
|
Hum Mol Genet
|
2009
|
1.61
|
50
|
Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.
|
PLoS Genet
|
2013
|
1.57
|
51
|
Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes.
|
Diabetes
|
2013
|
1.25
|
52
|
Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns.
|
Hum Genet
|
2005
|
1.18
|
53
|
The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects.
|
Hum Mol Genet
|
2009
|
1.09
|
54
|
Estimating hepatic glucokinase activity using a simple model of lactate kinetics.
|
Diabetes Care
|
2012
|
1.07
|
55
|
Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men.
|
Diabetes
|
2011
|
0.99
|
56
|
Identification of quantitative trait loci for susceptibility to mouse adenovirus type 1.
|
J Virol
|
2005
|
0.95
|
57
|
Coordinated genetic control of neoplastic and nonneoplastic diseases in mice.
|
J Gerontol A Biol Sci Med Sci
|
2002
|
0.93
|
58
|
Genome-wide meta-analysis of common variant differences between men and women.
|
Hum Mol Genet
|
2012
|
0.88
|
59
|
No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.
|
Diabetes
|
2012
|
0.86
|
60
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
61
|
ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition.
|
medRxiv
|
2020
|
0.75
|
62
|
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
PLoS Genet
|
2017
|
0.75
|