MicroRNAs miR-186 and miR-150 down-regulate expression of the pro-apoptotic purinergic P2X7 receptor by activation of instability sites at the 3'-untranslated region of the gene that decrease steady-state levels of the transcript.

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Published in J Biol Chem on August 05, 2008

Authors

Lingyin Zhou1, Xiaoping Qi, Judith A Potashkin, Fadi W Abdul-Karim, George I Gorodeski

Author Affiliations

1: Department of Reproductive Biology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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