Published in J Physiol on September 01, 1999
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett (2007) 3.19
Proteomic and functional evidence for a P2X7 receptor signalling complex. EMBO J (2001) 2.34
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The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes. Glia (2005) 1.42
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A truncated P2X7 receptor variant (P2X7-j) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization. J Biol Chem (2006) 1.30
A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice. J Biol Chem (2009) 1.29
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Experimental characterization and mathematical modeling of P2X7 receptor channel gating. J Neurosci (2010) 1.25
Permeation properties of a P2X receptor in the green algae Ostreococcus tauri. J Biol Chem (2008) 1.22
Exocytosis of ATP from astrocyte progenitors modulates spontaneous Ca2+ oscillations and cell migration. Glia (2007) 1.16
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Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis. J Biol Chem (2009) 1.07
Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol (2012) 1.06
Functional interactions between P2X4 and P2X7 receptors from mouse salivary epithelia. J Physiol (2009) 1.05
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Many ways to dilate the P2X7 receptor pore. Br J Pharmacol (2011) 0.95
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A novel chloride conductance activated by extracellular ATP in mouse parotid acinar cells. J Physiol (2002) 0.94
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Clemastine potentiates the human P2X7 receptor by sensitizing it to lower ATP concentrations. J Biol Chem (2011) 0.90
Maitotoxin-induced membrane blebbing and cell death in bovine aortic endothelial cells. BMC Physiol (2001) 0.90
Heteromeric assembly of P2X subunits. Front Cell Neurosci (2013) 0.90
Expression and function of the purinergic receptor P2X7 in patients with pulmonary tuberculosis. Clin Exp Immunol (2006) 0.89
Lymphocytes from P2X7-deficient mice exhibit enhanced P2X7 responses. J Leukoc Biol (2009) 0.89
Large-conductance channel formation mediated by P2X7 receptor activation is regulated through distinct intracellular signaling pathways in peritoneal macrophages and 2BH4 cells. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.89
Modulation of mouse embryonic stem cell proliferation and neural differentiation by the P2X7 receptor. PLoS One (2014) 0.89
C terminus of the P2X7 receptor: treasure hunting. Purinergic Signal (2011) 0.89
Effects of toxic cellular stresses and divalent cations on the human P2X7 cell death receptor. Mol Vis (2008) 0.87
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Dual gating mechanism and function of P2X7 receptor channels. Biophys J (2013) 0.86
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The P2X7 receptor supports both life and death in fibrogenic pancreatic stellate cells. PLoS One (2012) 0.86
Na+ modulates anion permeation and block of P2X7 receptors from mouse parotid glands. J Membr Biol (2008) 0.85
The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells. Mol Cancer (2015) 0.84
ATP induces the death of developing avian retinal neurons in culture via activation of P2X7 and glutamate receptors. Purinergic Signal (2012) 0.83
P2X receptor intermediate activation states have altered nucleotide selectivity. J Neurosci (2013) 0.83
P2X7 purinoceptors contribute to the death of Schwann cells transplanted into the spinal cord. Cell Death Dis (2013) 0.83
Different properties of P2X(7) receptor in hippocampal and cortical astrocytes. Purinergic Signal (2009) 0.83
P2X7 receptor stimulation of membrane internalization in a thyrocyte cell line. J Membr Biol (2005) 0.83
Allosteric regulation of the P2X4 receptor channel pore dilation. Pflugers Arch (2014) 0.83
Evaluation of YO-PRO-1 as an early marker of apoptosis following radiofrequency ablation of colon cancer liver metastases. Cytotechnology (2013) 0.82
The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance. Purinergic Signal (2009) 0.82
Involvement of P2X receptors in the NAD(+)-induced rise in [Ca (2+)] (i) in human monocytes. Purinergic Signal (2009) 0.82
Distinct contributions by ionotropic purinoceptor subtypes to ATP-evoked calcium signals in mouse parotid acinar cells. J Physiol (2012) 0.81
Microfluorimetric analysis of a purinergic receptor (P2X7) in GH4C1 rat pituitary cells: effects of a bioactive substance produced by Pfiesteria piscicida. Environ Health Perspect (2001) 0.81
P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2. J Cell Sci (2015) 0.80
Interleukin-1β has trophic effects in microglia and its release is mediated by P2X7R pore. J Neuroinflammation (2016) 0.80
Purinergic regulation of inflammasome activation after central nervous system injury. J Gen Physiol (2012) 0.80
Differential regulation of ca(2+) signaling and membrane trafficking by multiple p2 receptors in brown adipocytes. J Membr Biol (2005) 0.79
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Activation kinetics of single P2X receptors. Purinergic Signal (2007) 0.78
Differential membrane redistribution of P2X receptor isoforms in response to osmotic and hyperglycemic stress in the rat lens. Histochem Cell Biol (2009) 0.77
The P2X(7) receptor mediates the uptake of organic cations in canine erythrocytes and mononuclear leukocytes: comparison to equivalent human cell types. Purinergic Signal (2009) 0.77
Connexin hemichannel and pannexin channel electrophysiology: how do they differ? FEBS Lett (2014) 0.77
Extracellular ATP is cytotoxic to mononuclear phagocytes but does not induce killing of intracellular Mycobacterium avium subsp. paratuberculosis. Clin Vaccine Immunol (2007) 0.77
The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance. Purinergic Signal (2008) 0.77
Formulation and cytotoxicity evaluation of new self-emulsifying multiple W/O/W nanoemulsions. Int J Nanomedicine (2013) 0.76
Inhibition of P2X receptors protects human monocytes against damage by leukotoxin from Aggregatibacter actinomycetemcomitans and α-hemolysin from Escherichia coli. Infect Immun (2016) 0.76
Saffron reduces ATP-induced retinal cytotoxicity by targeting P2X7 receptors. Purinergic Signal (2016) 0.76
Use of Brilliant Blue FCF during vein graft preparation inhibits intimal hyperplasia. J Vasc Surg (2016) 0.76
Localization of the gate and selectivity filter of the full-length P2X7 receptor. Proc Natl Acad Sci U S A (2017) 0.76
Invited Lectures : Overviews Purinergic signalling: past, present and future. Purinergic Signal (2006) 0.75
P2X7 receptor-mediated TG2 externalization: a link to inflammatory arthritis? Amino Acids (2016) 0.75
Predictions suggesting a participation of beta-sheet configuration in the M2 domain of the P2X(7) receptor: a novel conformation? Biophys J (2009) 0.75
Diadenosine homodinucleotide products of ADP-ribosyl cyclases behave as modulators of the purinergic receptor P2X7. J Biol Chem (2010) 0.75
Quantitative Limits on Small Molecule Transport via the Electropermeome - Measuring and Modeling Single Nanosecond Perturbations. Sci Rep (2017) 0.75
Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function. PLoS One (2016) 0.75
Targeting of the P2X7 receptor in pancreatic cancer and stellate cells. Int J Cancer (2016) 0.75
Cell blebbing upon addition of cryoprotectants: a self-protection mechanism. PLoS One (2015) 0.75
Deciphering the regulation of P2X4 receptor channel gating by ivermectin using Markov models. PLoS Comput Biol (2017) 0.75
ATP-induced Ca(2+)-signalling mechanisms in the regulation of mesenchymal stem cell migration. Cell Mol Life Sci (2017) 0.75
P2X7 receptor as a novel drug delivery system to increase the entrance of hydrophilic drugs into cells during photodynamic therapy. J Bioenerg Biomembr (2016) 0.75
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