| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling.
|
Cell
|
2006
|
10.06
|
|
2
|
Viral reorganization of the secretory pathway generates distinct organelles for RNA replication.
|
Cell
|
2010
|
4.47
|
|
3
|
Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells.
|
J Cell Biol
|
2006
|
3.56
|
|
4
|
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1.
|
Nat Cell Biol
|
2006
|
3.19
|
|
5
|
Phosphatidylinositol 4-kinases: old enzymes with emerging functions.
|
Trends Cell Biol
|
2006
|
3.06
|
|
6
|
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment.
|
Cell Host Microbe
|
2011
|
3.05
|
|
7
|
PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity.
|
Science
|
2012
|
3.05
|
|
8
|
Visualization and manipulation of plasma membrane-endoplasmic reticulum contact sites indicates the presence of additional molecular components within the STIM1-Orai1 Complex.
|
J Biol Chem
|
2007
|
3.02
|
|
9
|
Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.
|
Proc Natl Acad Sci U S A
|
2007
|
2.52
|
|
10
|
Dual regulation of TRPV1 by phosphoinositides.
|
J Neurosci
|
2007
|
2.48
|
|
11
|
A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1.
|
Mol Biol Cell
|
2005
|
2.39
|
|
12
|
Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains.
|
Mol Biol Cell
|
2007
|
2.15
|
|
13
|
Activation of STIM1-Orai1 involves an intramolecular switching mechanism.
|
Sci Signal
|
2010
|
1.89
|
|
14
|
Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners.
|
J Cell Sci
|
2005
|
1.80
|
|
15
|
Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments.
|
J Biol Chem
|
2002
|
1.78
|
|
16
|
Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalpha.
|
Mol Biol Cell
|
2007
|
1.77
|
|
17
|
Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130.
|
J Biol Chem
|
2002
|
1.61
|
|
18
|
Live cell imaging of phosphoinositide dynamics with fluorescent protein domains.
|
Biochim Biophys Acta
|
2006
|
1.53
|
|
19
|
Phosphatidylinositol 4-kinase IIIbeta regulates the transport of ceramide between the endoplasmic reticulum and Golgi.
|
J Biol Chem
|
2006
|
1.52
|
|
20
|
c-Met must translocate to the nucleus to initiate calcium signals.
|
J Biol Chem
|
2007
|
1.52
|
|
21
|
A highly dynamic ER-derived phosphatidylinositol-synthesizing organelle supplies phosphoinositides to cellular membranes.
|
Dev Cell
|
2011
|
1.50
|
|
22
|
Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor.
|
J Cell Biol
|
2002
|
1.43
|
|
23
|
Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling.
|
Proc Natl Acad Sci U S A
|
2010
|
1.42
|
|
24
|
Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides.
|
J Biol Chem
|
2009
|
1.36
|
|
25
|
A membrane capture assay for lipid kinase activity.
|
Nat Protoc
|
2007
|
1.32
|
|
26
|
Structural determinants of Ras-Raf interaction analyzed in live cells.
|
Mol Biol Cell
|
2002
|
1.31
|
|
27
|
Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study.
|
BMC Cell Biol
|
2009
|
1.31
|
|
28
|
A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi.
|
J Cell Biol
|
2014
|
1.31
|
|
29
|
Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms.
|
Trends Biochem Sci
|
2012
|
1.29
|
|
30
|
Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate.
|
J Cell Biol
|
2007
|
1.25
|
|
31
|
Targeted expression of the inositol 1,4,5-triphosphate receptor (IP3R) ligand-binding domain releases Ca2+ via endogenous IP3R channels.
|
Proc Natl Acad Sci U S A
|
2005
|
1.24
|
|
32
|
Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis.
|
J Cell Biol
|
2009
|
1.23
|
|
33
|
STIM and Orai: the long-awaited constituents of store-operated calcium entry.
|
Trends Pharmacol Sci
|
2009
|
1.20
|
|
34
|
Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels.
|
J Biol Chem
|
2014
|
1.15
|
|
35
|
Visualization and manipulation of phosphoinositide dynamics in live cells using engineered protein domains.
|
Pflugers Arch
|
2007
|
1.14
|
|
36
|
Live cell imaging of phosphoinositides with expressed inositide binding protein domains.
|
Methods
|
2008
|
1.11
|
|
37
|
G protein-coupled receptor-promoted trafficking of Gbeta1gamma2 leads to AKT activation at endosomes via a mechanism mediated by Gbeta1gamma2-Rab11a interaction.
|
Mol Biol Cell
|
2008
|
1.08
|
|
38
|
Design of drug-resistant alleles of type-III phosphatidylinositol 4-kinases using mutagenesis and molecular modeling.
|
Biochemistry
|
2008
|
1.06
|
|
39
|
Enteropathogenic Escherichia coli subverts phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate upon epithelial cell infection.
|
Mol Biol Cell
|
2008
|
1.03
|
|
40
|
Intracellular curvature-generating proteins in cell-to-cell fusion.
|
Biochem J
|
2011
|
1.02
|
|
41
|
Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase.
|
Mol Biol Cell
|
2012
|
1.00
|
|
42
|
The dynamics of plasma membrane PtdIns(4,5)P(2) at fertilization of mouse eggs.
|
J Cell Sci
|
2002
|
0.99
|
|
43
|
Acute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor.
|
J Cell Sci
|
2012
|
0.95
|
|
44
|
A homogeneous and nonisotopic assay for phosphatidylinositol 4-kinases.
|
Anal Biochem
|
2011
|
0.94
|
|
45
|
A PH domain in the Arf GTPase-activating protein (GAP) ARAP1 binds phosphatidylinositol 3,4,5-trisphosphate and regulates Arf GAP activity independently of recruitment to the plasma membranes.
|
J Biol Chem
|
2009
|
0.92
|
|
46
|
Inositol lipid regulation of lipid transfer in specialized membrane domains.
|
Trends Cell Biol
|
2013
|
0.90
|
|
47
|
Store-operated Ca2+ influx and subplasmalemmal mitochondria.
|
Cell Calcium
|
2009
|
0.90
|
|
48
|
Crucial role of phosphatidylinositol 4-kinase IIIalpha in development of zebrafish pectoral fin is linked to phosphoinositide 3-kinase and FGF signaling.
|
J Cell Sci
|
2009
|
0.89
|
|
49
|
Recruitment of arfaptins to the trans-Golgi network by PI(4)P and their involvement in cargo export.
|
EMBO J
|
2013
|
0.87
|
|
50
|
Secretion of VEGF-165 has unique characteristics, including shedding from the plasma membrane.
|
Mol Biol Cell
|
2014
|
0.86
|
|
51
|
The pleckstrin homology domain of phosphoinositide-specific phospholipase Cdelta4 is not a critical determinant of the membrane localization of the enzyme.
|
J Biol Chem
|
2004
|
0.86
|
|
52
|
Phosphoinositide 3-kinase is required for intracellular Listeria monocytogenes actin-based motility and filopod formation.
|
J Biol Chem
|
2005
|
0.86
|
|
53
|
Distinct properties of the two isoforms of CDP-diacylglycerol synthase.
|
Biochemistry
|
2014
|
0.80
|
|
54
|
Demonstration of angiotensin II-induced Ras activation in the trans-Golgi network and endoplasmic reticulum using bioluminescence resonance energy transfer-based biosensors.
|
J Biol Chem
|
2010
|
0.79
|
|
55
|
Genetic and functional studies of phosphatidyl-inositol 4-kinase type IIIα.
|
Biochim Biophys Acta
|
2011
|
0.79
|
|
56
|
βIII spectrin regulates the structural integrity and the secretory protein transport of the Golgi complex.
|
J Biol Chem
|
2012
|
0.78
|