Published in Biochemistry on September 05, 2008
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Versatile TPR domains accommodate different modes of target protein recognition and function. Cell Stress Chaperones (2010) 1.47
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FKBP51-a selective modulator of glucocorticoid and androgen sensitivity. Curr Opin Pharmacol (2011) 0.96
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Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study. Reprod Biol Endocrinol (2010) 0.84
FKBP51 reciprocally regulates GRα and PPARγ activation via the Akt-p38 pathway. Mol Endocrinol (2014) 0.83
Management of cytoskeleton architecture by molecular chaperones and immunophilins. Cell Signal (2011) 0.81
Nuclear lipid microdomain as resting place of dexamethasone to impair cell proliferation. Int J Mol Sci (2014) 0.81
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The FKBP5 Gene Affects Alcohol Drinking in Knockout Mice and Is Implicated in Alcohol Drinking in Humans. Int J Mol Sci (2016) 0.76
Development and validation of a robust and sensitive assay for the discovery of selective inhibitors for serine/threonine protein phosphatases PP1α (PPP1C) and PP5 (PPP5C). Assay Drug Dev Technol (2014) 0.76
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Steroid Receptor-Associated Immunophilins: A Gateway to Steroid Signalling. Clin Biochem Rev (2015) 0.75
FKBP51 regulates cell motility and invasion via RhoA signaling. Cancer Sci (2016) 0.75
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Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis. Dev Cell (2008) 2.13
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. Cancer Cell (2011) 2.04
Essential role for Co-chaperone Fkbp52 but not Fkbp51 in androgen receptor-mediated signaling and physiology. J Biol Chem (2006) 1.66
Acute doxorubicin cardiotoxicity is associated with p53-induced inhibition of the mammalian target of rapamycin pathway. Circulation (2008) 1.61
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Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells. Nat Cell Biol (2011) 1.49
Fkbp52 regulates androgen receptor transactivation activity and male urethra morphogenesis. J Biol Chem (2010) 1.46
Glucocorticoid receptor physiology. Rev Endocr Metab Disord (2007) 1.45
Discovery of glucocorticoid receptor-beta in mice with a role in metabolism. Mol Endocrinol (2010) 1.29
Abnormal cardiac development in the absence of heart glycogen. Mol Cell Biol (2004) 1.28
Novel avian-origin human influenza A(H7N9) can be transmitted between ferrets via respiratory droplets. J Infect Dis (2013) 1.28
FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor A isoform. Mol Endocrinol (2006) 1.25
Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac function. J Biol Chem (2008) 1.24
Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development (2011) 1.24
Impaired nuclear transport and uncoating limit recombinant adeno-associated virus 2 vector-mediated transduction of primary murine hematopoietic cells. Hum Gene Ther (2004) 1.23
Role of cellular FKBP52 protein in intracellular trafficking of recombinant adeno-associated virus 2 vectors. Virology (2006) 1.21
Smad7 is required for the development and function of the heart. J Biol Chem (2008) 1.18
Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system. Neuron (2012) 1.18
Protein phosphatase 5 mediates lipid metabolism through reciprocal control of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ (PPARγ). J Biol Chem (2011) 1.13
The immunophilin ligands cyclosporin A and FK506 suppress prostate cancer cell growth by androgen receptor-dependent and -independent mechanisms. Endocrinology (2007) 1.12
Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth. J Biol Chem (2006) 1.12
L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1. EMBO J (2011) 1.10
SDF-1/CXCR4 mediates acute protection of cardiac function through myocardial STAT3 signaling following global ischemia/reperfusion injury. Am J Physiol Heart Circ Physiol (2011) 1.09
Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development. Proc Natl Acad Sci U S A (2013) 1.07
Analysis of ventricular hypertrabeculation and noncompaction using genetically engineered mouse models. Pediatr Cardiol (2009) 1.04
Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy. Hum Mol Genet (2011) 1.04
Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade. Stem Cell Res Ther (2013) 1.04
FKBP12 is a critical regulator of the heart rhythm and the cardiac voltage-gated sodium current in mice. Circ Res (2011) 0.99
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The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus. Virol J (2013) 0.99
Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest. J Biol Chem (2007) 0.98
Susceptibility to diet-induced hepatic steatosis and glucocorticoid resistance in FK506-binding protein 52-deficient mice. Endocrinology (2010) 0.98
Molecular mechanism of ventricular trabeculation/compaction and the pathogenesis of the left ventricular noncompaction cardiomyopathy (LVNC). Am J Med Genet C Semin Med Genet (2013) 0.96
Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia. J Biol Chem (2009) 0.96
FKBP51-a selective modulator of glucocorticoid and androgen sensitivity. Curr Opin Pharmacol (2011) 0.96
A mouse model for juvenile doxorubicin-induced cardiac dysfunction. Pediatr Res (2008) 0.92
Targeted ablation reveals a novel role of FKBP52 in gene-specific regulation of glucocorticoid receptor transcriptional activity. J Steroid Biochem Mol Biol (2008) 0.92
Distinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cells. Proc Natl Acad Sci U S A (2003) 0.91
Lack of plakoglobin in epidermis leads to keratoderma. J Biol Chem (2012) 0.90
Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt protein. J Biol Chem (2012) 0.90
Peroxisome proliferator-activated receptor δ agonist, HPP593, prevents renal necrosis under chronic ischemia. PLoS One (2013) 0.89
FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506. Transplantation (2002) 0.87
2008 Riley Heart Center Symposium on cardiac development: growth and morphogenesis of the ventricular wall. Pediatr Cardiol (2009) 0.86
FKBP38 peptidylprolyl isomerase promotes the folding of cystic fibrosis transmembrane conductance regulator in the endoplasmic reticulum. J Biol Chem (2011) 0.86
Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity. Development (2013) 0.86
Tbx20 transcription factor is a downstream mediator for bone morphogenetic protein-10 in regulating cardiac ventricular wall development and function. J Biol Chem (2011) 0.86
The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity. J Physiol (2012) 0.84
FKBP51 reciprocally regulates GRα and PPARγ activation via the Akt-p38 pathway. Mol Endocrinol (2014) 0.83
Enhancement of glucocorticoid receptor-mediated gene expression by constitutively active heat shock factor 1. Mol Endocrinol (2003) 0.83
Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-β pathway. Cell Signal (2012) 0.83
FKBP51 controls cellular adipogenesis through p38 kinase-mediated phosphorylation of GRα and PPARγ. Mol Endocrinol (2014) 0.82
Cardiac sodium channel Nav1.5 mutations and cardiac arrhythmia. Pediatr Cardiol (2012) 0.81
Phosphatase of regenerating liver 2 (PRL2) deficiency impairs Kit signaling and spermatogenesis. J Biol Chem (2013) 0.81
Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation. BMC Cell Biol (2013) 0.81
Impaired function of Fanconi anemia type C-deficient macrophages. J Leukoc Biol (2011) 0.79
Reduced glucocorticoid receptor protein expression in children with critical illness. Horm Res Paediatr (2013) 0.79
Transgenic analysis of the role of FKBP12.6 in cardiac function and intracellular calcium release. Assay Drug Dev Technol (2011) 0.78
Myocardial Mycn is essential for mouse ventricular wall morphogenesis. Dev Biol (2012) 0.77
The role of FK506-binding proteins 12 and 12.6 in regulating cardiac function. Pediatr Cardiol (2012) 0.76
A glimpse of Cre-mediated controversies in epicardial signalling. Cardiovasc Res (2013) 0.75
Functional screening of intracardiac cell transplants using two-photon fluorescence microscopy. Pediatr Cardiol (2012) 0.75
Vanadate increases glucocorticoid receptor-mediated gene expression: a novel mechanism for potentiation of a steroid receptor. J Steroid Biochem Mol Biol (2002) 0.75
Reconstitution of TGF-beta sensitivity in the VACO-411 human colon carcinoma line by somatic cell fusion with MCF-7. J Biomed Sci (2003) 0.75
2011 Riley Heart Center Symposium on cardiac development: development of the cardiac conduction system and arrhythmias. Pediatr Cardiol (2012) 0.75