Published in Circ Res on March 03, 2011
Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy. Hum Mol Genet (2011) 1.04
Analysing the visible conformational substates of the FK506-binding protein FKBP12. Biochem J (2013) 0.86
Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity. Development (2013) 0.86
Liver-specific NG37 overexpression leads to diet-dependent fatty liver disease accompanied by cardiac dysfunction. Genes Nutr (2016) 0.82
Structural basis of conformational transitions in the active site and 80's loop in the FK506-binding protein FKBP12. Biochem J (2014) 0.80
Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci (2015) 0.79
Transgenic analysis of the role of FKBP12.6 in cardiac function and intracellular calcium release. Assay Drug Dev Technol (2011) 0.78
Effects of tacrolimus on action potential configuration and transmembrane ion currents in canine ventricular cells. Naunyn Schmiedebergs Arch Pharmacol (2012) 0.78
Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6. Acta Crystallogr D Biol Crystallogr (2014) 0.77
Statistical allosteric coupling to the active site indole ring flip equilibria in the FK506-binding domain. Biophys Chem (2014) 0.77
The role of FK506-binding proteins 12 and 12.6 in regulating cardiac function. Pediatr Cardiol (2012) 0.76
Characterization of tubular liquid crystal structure in embryonic stem cell derived embryoid bodies. Cell Biosci (2017) 0.75
Na+-induced Ca2+ influx through reverse mode of Na+-Ca2+ exchanger in mouse ventricular cardiomyocyte. Oncotarget (2015) 0.75
FK506-binding proteins 12 and 12.6 (FKBPs) as regulators of cardiac Ryanodine Receptors: insights from new functional and structural knowledge. Channels (Austin) (2017) 0.75
Murine Electrophysiological Models of Cardiac Arrhythmogenesis. Physiol Rev (2017) 0.75
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. Cell (1995) 7.73
Basic mechanisms of cardiac impulse propagation and associated arrhythmias. Physiol Rev (2004) 5.79
Ionic mechanisms of propagation in cardiac tissue. Roles of the sodium and L-type calcium currents during reduced excitability and decreased gap junction coupling. Circ Res (1997) 4.86
Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43. Circ Res (2001) 4.38
Coupled gating between individual skeletal muscle Ca2+ release channels (ryanodine receptors) Science (1998) 4.16
Resurgence of sodium channel research. Annu Rev Physiol (2001) 4.11
Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A). J Clin Invest (2003) 3.00
Cardiac conduction defects associate with mutations in SCN5A. Nat Genet (1999) 2.73
Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy. Nature (2002) 2.59
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome. Nat Med (2001) 2.46
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12. Nature (1998) 2.31
Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks. Circ Res (2010) 2.29
Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins. Trends Cardiovasc Med (2005) 1.97
Cardiac sodium channel overlap syndromes: different faces of SCN5A mutations. Trends Cardiovasc Med (2008) 1.68
Selective binding of FKBP12.6 by the cardiac ryanodine receptor. J Biol Chem (1996) 1.64
Sinus arrest during tacrolimus (FK506) and digitalis treatment in a bone marrow transplant recipient. Transplantation (1997) 1.46
Immunophilins and the nervous system. Nat Med (1995) 1.34
Effects of FK-506 on contraction and Ca2+ transients in rat cardiac myocytes. Circ Res (1996) 1.28
Altered excitation-contraction coupling with skeletal muscle specific FKBP12 deficiency. FASEB J (2004) 1.24
FKBP binding characteristics of cardiac microsomes from diverse vertebrates. Biochem Biophys Res Commun (2001) 1.24
Correlation of repolarization of ventricular monophasic action potential with ECG in the murine heart. Am J Physiol Heart Circ Physiol (2002) 1.22
Mechanistic links between Na+ channel (SCN5A) mutations and impaired cardiac pacemaking in sick sinus syndrome. Circ Res (2010) 1.18
Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth. J Biol Chem (2006) 1.12
Quantitative relationship between myocardial concentration of tacrolimus and QT prolongation in guinea pigs: pharmacokinetic/pharmacodynamic model incorporating a site of adverse effect. J Pharmacokinet Pharmacodyn (2001) 0.96
Calcium channel diversity in the cardiovascular system. J Am Coll Cardiol (1996) 0.91
Channelopathies: a new category of diseases causing sudden death. Herz (2007) 0.87
QT prolongation and near fatal cardiac arrhythmia after intravenous tacrolimus administration: a case report. Transplantation (1998) 0.85
Sustained QT prolongation induced by tacrolimus in guinea pigs. Life Sci (1999) 0.84
Pharmacokinetic/pharmacodynamic analysis of tacrolimus-induced QT prolongation in guinea pigs. Biol Pharm Bull (1999) 0.82
Bradycardia associated with intravenous administration of tacrolimus in a liver transplant recipient. Pharmacotherapy (1998) 0.81
QT prolongation and Torsades de Pointes after administration of FK506. Transplantation (1992) 0.78
Sinus arrest during tacrolimus treatment: was the QT interval prolonged? Transplantation (1998) 0.77
Prolonged cardiac repolarization after tacrolimus and haloperidol administration in the critically ill patient. Pharmacotherapy (2004) 0.77
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature (2008) 10.27
Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature (2004) 8.87
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature (2003) 5.94
Calmodulin kinase II inhibition protects against structural heart disease. Nat Med (2005) 5.87
Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection. J Heart Lung Transplant (2005) 5.87
ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation. Cell Metab (2005) 4.79
FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell (2003) 4.68
LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell (2013) 4.58
Antibody-mediated rejection criteria - an addition to the Banff 97 classification of renal allograft rejection. Am J Transplant (2003) 4.54
A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates. Biophys J (2008) 4.22
Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection. J Heart Lung Transplant (2007) 3.90
From pulsus to pulseless: the saga of cardiac alternans. Circ Res (2006) 3.83
T-tubule remodeling during transition from hypertrophy to heart failure. Circ Res (2010) 3.57
Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop. Circulation (2009) 3.50
Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release. Biophys J (2002) 3.38
Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1. Circ Res (2004) 3.30
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc Natl Acad Sci U S A (2003) 3.21
Calcium flickers steer cell migration. Nature (2008) 3.01
Cardiomyocyte cell cycle regulation. Circ Res (2002) 2.99
Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop. Circulation (2010) 2.94
Cardiac regeneration: repopulating the heart. Annu Rev Physiol (2006) 2.92
Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice. Circ Res (2004) 2.92
Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient Mice by altering lymphocyte and macrophage phenotypes. Circ Res (2002) 2.85
Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression. Circ Res (2009) 2.82
CaMKII determines mitochondrial stress responses in heart. Nature (2012) 2.63
Spontaneous stellate ganglion nerve activity and ventricular arrhythmia in a canine model of sudden death. Heart Rhythm (2007) 2.62
The dynamics of cardiac fibrillation. Circulation (2005) 2.58
Ca2+ blinks: rapid nanoscopic store calcium signaling. Proc Natl Acad Sci U S A (2005) 2.56
Notch signaling is essential for ventricular chamber development. Dev Cell (2007) 2.53
Cardiomyogenic potential of C-kit(+)-expressing cells derived from neonatal and adult mouse hearts. Circulation (2010) 2.52
BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development (2004) 2.50
Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res (2006) 2.47
Left stellate ganglion and vagal nerve activity and cardiac arrhythmias in ambulatory dogs with pacing-induced congestive heart failure. J Am Coll Cardiol (2007) 2.46
Mechanisms of cardiac nerve sprouting after myocardial infarction in dogs. Circ Res (2004) 2.45
Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. Circulation (2003) 2.37
Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure. Circ Res (2002) 2.36
Axial stretch of rat single ventricular cardiomyocytes causes an acute and transient increase in Ca2+ spark rate. Circ Res (2009) 2.35
Cell-based cardiac repair: reflections at the 10-year point. Circulation (2005) 2.25
Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Mol Cell Biol (2011) 2.23
Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice. J Clin Invest (2003) 2.23
Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines. Circulation (2008) 2.20
Differential cardiac remodeling in preload versus afterload. Circulation (2010) 2.20
Value of high-density endocardial and epicardial mapping for catheter ablation of hemodynamically unstable ventricular tachycardia. Heart Rhythm (2006) 2.18
Proarrhythmic defects in Timothy syndrome require calmodulin kinase II. Circulation (2008) 2.16
Physiological coupling of donor and host cardiomyocytes after cellular transplantation. Circ Res (2003) 2.14
Proarrhythmic effect of blocking the small conductance calcium activated potassium channel in isolated canine left atrium. Heart Rhythm (2013) 2.14
Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis. Dev Cell (2008) 2.13
Cardiomyocyte-secreted acetylcholine is required for maintenance of homeostasis in the heart. FASEB J (2013) 2.12
Ventricular septal rupture after acute myocardial infarction. N Engl J Med (2002) 2.11
Purinergic and vanilloid receptor activation releases glutamate from separate cranial afferent terminals in nucleus tractus solitarius. J Neurosci (2004) 2.08
Coronary vasodilation by noninvasive transcutaneous ultrasound: an in vivo canine study. J Am Coll Cardiol (2003) 2.06
Circadian variations of stellate ganglion nerve activity in ambulatory dogs. Heart Rhythm (2006) 2.06
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. Cancer Cell (2011) 2.04
Autonomic nervous system activity measured directly and QT interval variability in normal and pacing-induced tachycardia heart failure dogs. J Am Coll Cardiol (2009) 1.99
Sympathetic nerve sprouting, electrical remodeling, and increased vulnerability to ventricular fibrillation in hypercholesterolemic rabbits. Circ Res (2003) 1.97
Diastolic intracellular calcium-membrane voltage coupling gain and postshock arrhythmias: role of purkinje fibers and triggered activity. Circ Res (2009) 1.96
Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma. Blood (2011) 1.95
Calmodulin kinase II is required for fight or flight sinoatrial node physiology. Proc Natl Acad Sci U S A (2009) 1.95
A novel intracellular protein delivery platform based on single-protein nanocapsules. Nat Nanotechnol (2009) 1.94
Intracellular calcium dynamics and acceleration of sinus rhythm by beta-adrenergic stimulation. Circulation (2009) 1.91
Cardiomyocyte cell cycle activation improves cardiac function after myocardial infarction. Cardiovasc Res (2007) 1.90
Mechanisms of recurrent ventricular fibrillation in a rabbit model of pacing-induced heart failure. Heart Rhythm (2009) 1.89
Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. Nat Med (2011) 1.88
Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias. Proc Natl Acad Sci U S A (2006) 1.87
Early afterdepolarizations and cardiac arrhythmias. Heart Rhythm (2010) 1.86
Expression of mutant p193 and p53 permits cardiomyocyte cell cycle reentry after myocardial infarction in transgenic mice. Circ Res (2004) 1.84
Molecular, endocrine, and genetic mechanisms of arterial calcification. Endocr Rev (2004) 1.83
Reduction of P-wave duration and successful pulmonary vein isolation in patients with atrial fibrillation. J Cardiovasc Electrophysiol (2007) 1.82
Thermodynamically irreversible gating of ryanodine receptors in situ revealed by stereotyped duration of release in Ca(2+) sparks. Biophys J (2002) 1.80
Estrogen receptor signaling pathways in human non-small cell lung cancer. Steroids (2007) 1.80
Lung cancer chemoprevention with celecoxib in former smokers. Cancer Prev Res (Phila) (2011) 1.77
Adult bone marrow-derived cells do not acquire functional attributes of cardiomyocytes when transplanted into peri-infarct myocardium. Mol Ther (2008) 1.75