Published in Oncogene on September 18, 2008
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Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth. Proc Natl Acad Sci U S A (2011) 3.14
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A putative role for microRNA-205 in mammary epithelial cell progenitors. J Cell Sci (2010) 1.47
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Early generalized overgrowth in boys with autism. Arch Gen Psychiatry (2011) 1.40
SDF-1α induction in mature smooth muscle cells by inactivation of PTEN is a critical mediator of exacerbated injury-induced neointima formation. Arterioscler Thromb Vasc Biol (2011) 1.27
PTEN at a glance. J Cell Sci (2012) 1.26
ProNGF induces PTEN via p75NTR to suppress Trk-mediated survival signaling in brain neurons. J Neurosci (2010) 1.12
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Leptin-dependent phosphorylation of PTEN mediates actin restructuring and activation of ATP-sensitive K+ channels. J Biol Chem (2009) 0.95
Concomitant loss of EAF2/U19 and Pten synergistically promotes prostate carcinogenesis in the mouse model. Oncogene (2013) 0.94
Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of mammalian target of rapamycin. PLoS One (2012) 0.92
New insights into the regulation and function of serine/threonine kinases in T lymphocytes. Immunol Rev (2009) 0.88
An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias. Dis Model Mech (2013) 0.87
Pten regulates collective cell migration during specification of the anterior-posterior axis of the mouse embryo. Dev Biol (2012) 0.86
PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility. Proc Natl Acad Sci U S A (2014) 0.86
Differential requirements for c-Myc in chronic hematopoietic hyperplasia and acute hematopoietic malignancies in Pten-null mice. Leukemia (2011) 0.85
The expression of PTEN is associated with improved prognosis in patients with ampullary adenocarcinoma after pancreaticoduodenectomy. Arch Pathol Lab Med (2013) 0.85
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Reorganization of Intact Descending Motor Circuits to Replace Lost Connections After Injury. Neurotherapeutics (2016) 0.81
TGF-β signaling alters the pattern of liver tumorigenesis induced by Pten inactivation. Oncogene (2014) 0.80
Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1. Oncogene (2012) 0.80
Phosphoinositides: Key modulators of energy metabolism. Biochim Biophys Acta (2014) 0.79
Modeling synovial sarcoma metastasis in the mouse: PI3'-lipid signaling and inflammation. J Exp Med (2016) 0.78
Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute to neuroprotection in a traumatic brain injury. Alzheimers Res Ther (2013) 0.78
Signals controlling un-differentiated states in embryonic stem and cancer cells: role of the phosphatidylinositol 3' kinase pathway. J Cell Physiol (2014) 0.78
PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland. Dev Biol (2015) 0.78
Aurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast cancer. Carcinogenesis (2016) 0.77
Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes. World J Gastroenterol (2012) 0.77
Cell Type-Specific and Inducible PTEN Gene Silencing by a Tetracycline Transcriptional Activator-Regulated Short Hairpin RNA. Mol Cells (2015) 0.76
Inhibition of JNK-mediated autophagy enhances NSCLC cell sensitivity to mTORC1/2 inhibitors. Sci Rep (2016) 0.76
Phosphatase and Tensin Homologue: Novel Regulation by Developmental Signaling. J Signal Transduct (2015) 0.75
Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition. Oncoimmunology (2016) 0.75
Cytokeratin 19 promoter directs the expression of Cre recombinase in various epithelia of transgenic mice. Oncotarget (2017) 0.75
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