Published in Proc Natl Acad Sci U S A on December 01, 1976
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Insulin activation of lipogenesis in isolated mammary acini from lactating rats fed on a high-fat diet. Evidence that acetyl-CoA carboxylase is a site of action. Biochem J (1987) 0.92
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A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate. Biochem J (1971) 8.85
The control of fatty acid and triglyceride synthesis in rat epididymal adipose tissue. Roles of coenzyme A derivatives, citrate and L-glycerol 3-phosphate. Biochem J (1968) 2.37
A procedure for measurement of distribution spaces in isolated fat cells. Biochim Biophys Acta (1972) 2.22
GLUCOSE UPTAKE BY INCUBATED RAT EPIDIDYMAL ADIPOSE TISSUE. RATE-LIMITING STEPS AND SITE OF INSULIN ACTION. J Biol Chem (1965) 2.10
The distribution of hepatic metabolites and the control of the pathways of carbohydrate metabolism in animals of different dietary and hormonal status. Arch Biochem Biophys (1971) 1.97
The effects of spontaneous obesity on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes. J Clin Invest (1976) 1.75
The isolation and metabolism of brown fat cells. J Biol Chem (1967) 1.66
Effects of epinephrine and insulin on phosphopeptide metabolism in adipocytes. J Biol Chem (1976) 1.47
Transport and phosphorylation of sugars in adipose tissue. Biochem J (1963) 1.44
Cytochalasin B-sensitive 2-deoxy-D-glucose transport in adipose cell ghosts. J Biol Chem (1973) 1.31
Effect of phenazine methosulfate on lipogenesis. J Biol Chem (1970) 1.21
Time course of insulin-receptor binding and insulin-induced lipogenesis in isolated rat fat cells. J Biol Chem (1975) 1.15
Adenosine triphosphate-dependent inhibition of insulin-stimulated glucose transport in fat cells. Possible role of membrane phosphorylation. J Biol Chem (1974) 1.13
Insulin: interaction with membrane receprots and relationship to cyclic purine nucleotides and cell growth. Fed Proc (1975) 1.11
Independence of the effects of epinephrine, glucagon, and adrenocorticotropin on glucose utilization from those on lipolysis in isolated rat adipose cells. J Biol Chem (1969) 1.09
Studies on the metabolism of adipose tissue. XI. Activation of phosphorylase by agents which stimulate lipolysis. Biochemistry (1962) 1.09
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Metabolism of isolated fat cells. VI. The effects of insulin, lipolytic hormones, and theophylline on glucose transport and metabolism in "ghosts". J Biol Chem (1967) 1.01
Inhibition of hormone-stimulated lipolysis by clofibrate. A possible mechanism for its hypolipidemic action. J Clin Invest (1975) 0.97
Glucose transport in fat cell membranes. J Biol Chem (1971) 0.95
Effect of glucocorticoids on the glucose transport system of isolated fat cells. J Biol Chem (1975) 0.93
The action of local anaesthetics on lipolysis and on adenosine 3':5'-cyclic monophosphate content in isolated rat fat-cells. Biochem J (1974) 0.92
Regulation of pentose phosphate pathway dehydrogenases by NADP+/NADPH ratios. Biochem Biophys Res Commun (1976) 0.85
Evidence for the involvement of cyclic-3',5'-adenosine monophosphate in glucose utilization by isolated rat epididymal adipose cells. Biochem Biophys Res Commun (1967) 0.83
Effect of amitriptyline on lipolysis and cyclic AMP concentration in isolated fat cells. Metabolism (1972) 0.83
Simulation and enhancement of the adipose tissue insulin response by procaine hydrochloride: evidence for a role of calcium in insulin action. Horm Metab Res (1974) 0.82
The effect of phenformin on lipolysis and the concentration of cyclic AMP and ATP in white fat cells. Endocrinology (1973) 0.82
Deuterium oxide stimulates glucose metabolism and inhibits lipolysis in rat epididymal adipose tissue. Biochem Biophys Res Commun (1975) 0.78
Mechanism of action of antilipolytic agents: comparison of the effects of insulin, tolbutamide, and phenformin on lipolysis induced by dibutyryl cyclic AMP plus theophylline. Metabolism (1969) 0.78
Paradoxical effects of theophylline and its interaction with insulin on glucose metabolism in adipose tissue. Eur J Biochem (1973) 0.77
Effects of growth hormone on the penetration of L-arabinose into adipose tissue. Endocrinology (1966) 0.77
The control of fatty acid and triglyceride synthesis in rat epididymal adipose tissue. Roles of coenzyme A derivatives, citrate and L-glycerol 3-phosphate. Biochem J (1968) 2.37
Postoperative hyponatremia despite near-isotonic saline infusion: a phenomenon of desalination. Ann Intern Med (1997) 2.33
Renal tubular acidosis and osteopetrosis with carbonic anhydrase II deficiency: pathogenesis of impaired acidification. Pediatr Nephrol (1997) 2.16
Quantitative analysis of amino acid oxidation and related gluconeogenesis in humans. Physiol Rev (1992) 2.12
Hypokalaemia and paralysis. QJM (2001) 1.72
Metabolic acidosis in the alcoholic: a pathophysiologic approach. Metabolism (1983) 1.70
Hyperglycemia-induced hyponatremia: metabolic considerations in calculation of serum sodium depression. Can Med Assoc J (1975) 1.66
Calcium ion fluxes induced by the action of alpha-adrenergic agonists in perfused rat liver. Biochem J (1982) 1.64
Importance of timing of risk factors for cerebral oedema during therapy for diabetic ketoacidosis. Arch Dis Child (2003) 1.63
Stable changes to calcium fluxes in mitochondria isolated from rat livers perfused with alpha-adrenergic agonists and with glucagon. Biochem J (1980) 1.52
How to select optimal maintenance intravenous fluid therapy. QJM (2003) 1.51
Glue-sniffing and distal renal tubular acidosis: sticking to the facts. J Am Soc Nephrol (1991) 1.50
Acidosis in a patient with cholera: a need to redefine concepts. QJM (2004) 1.47
An additional role for insulin in the control of fatty acid synthesis independent of glucose transport. Can J Biochem (1970) 1.47
A modified classification of metabolic acidosis: a pathophysiologic approach. Nephron (1992) 1.45
Sites of ammonia addition to tubular fluid in rats with chronic metabolic acidosis. Kidney Int (1981) 1.45
Treatment of acute hyponatremia: ensuring the excretion of a predictable amount of electrolyte-free water. Crit Care Med (2000) 1.44
Severe hypokalaemia in a Chinese male. QJM (2002) 1.42
Studies on alpha-adrenergic-induced respiration and glycogenolysis in perfused rat liver. J Biol Chem (1982) 1.42
The patient with a severe degree of metabolic acidosis: a deductive analysis. QJM (2006) 1.39
A procedure for the rapid preparation of mitochondria from rat liver. Biochem J (1982) 1.30
Studies on the pathogenesis of type I (distal) renal tubular acidosis as revealed by the urinary PCO2 tensions. J Clin Invest (1974) 1.30
The role of calcium ions in the mechanism of action of alpha-adrenergic agonists in rat liver. Biochem J (1984) 1.28
Regulation of glycolysis and L-glycerol 3-phosphate concentration in rat epididymal adipose tissue in vitro. Role of phosphofructokinase. Biochem J (1969) 1.27
The contribution of both extracellular and intracellular calcium to the action of alpha-adrenergic agonists in perfused rat liver. Biochem J (1984) 1.21
Factors that control the effect of pH on glycolysis in leukocytes. J Biol Chem (1969) 1.20
Transport of reduced nicotinamide-adenine dinucleotide into mitochondria of rat white adipose tissue. Biochem J (1970) 1.17
The transtubular potassium concentration in patients with hypokalemia and hyperkalemia. Am J Kidney Dis (1990) 1.17
Stimulation by alpha-adrenergic agonists of Ca2+ fluxes, mitochondrial oxidation and gluconeogenesis in perfused rat liver. Biochem J (1983) 1.13
Development of a test to evaluate the transtubular potassium concentration gradient in the cortical collecting duct in vivo. Miner Electrolyte Metab (1986) 1.10
Anorexia nervosa and chronic renal insufficiency: a prescription for disaster. QJM (2004) 1.09
Factors affecting the kinetics and equilibrium of exchange reactions of the citrate-transporting system of rat liver mitochondria. J Biol Chem (1971) 1.08
The role of macrophages in Acanthamoeba keratitis. Invest Ophthalmol Vis Sci (1996) 1.08
Effect of 2-methylcitrate on citrate metabolism: implications for the management of patients with propionic acidemia and methylmalonic aciduria. Pediatr Res (1975) 1.07
Interpretation of the serum potassium concentration in metabolic acidosis. Clin Invest Med (1979) 1.06
The action of alpha-adrenergic agonists on plasma-membrane calcium fluxes in perfused rat liver. Biochem J (1984) 1.05
Simian immunodeficiency virus (SIV)-specific CTL are present in large numbers in livers of SIV-infected rhesus monkeys. J Immunol (2000) 1.05
The role of the cytoplasmic redox potential in the control of fatty acid synthesis from glucose, pyruvate and lactate in white adipose tissue. Biochem J (1970) 1.05
Brain swelling after dialysis: old urea or new osmoles? Am J Kidney Dis (1996) 1.04
An assessment of the calcium content of rat liver mitochondria in vivo. Biochem J (1984) 1.03
Reduction in adipocyte ATP by lipolytic agents: relation to intracellular free fatty acid accumulation. J Lipid Res (1971) 1.02
New clinical approach to evaluate disorders of potassium excretion. Miner Electrolyte Metab (1986) 1.02
Hypokalaemia and paralysis. QJM (2003) 1.01
The effects of 2-ethylcitrate and tricarballylate on citrate transport in rat liver mitochondria and fatty acid synthesis in rat white adipose tissue. Eur J Biochem (1970) 1.00
Stable enhancement of ruthenium red-insensitive calcium transport in an endoplasmic reticulum-rich fraction following the exposure of isolated rat liver cells to glucagon. FEBS Lett (1979) 0.99
Thirty-second sampling of plasma growth hormone in man: correlation with sleep stages. J Clin Endocrinol Metab (1991) 0.98
Role of 3',5'-cyclic AMP in glucagon-induced stimulation of ruthenium red-insensitive calcium transport in an endoplasmic reticulum-rich fraction of rat liver. FEBS Lett (1980) 0.98
Urine electrolytes in the assessment of extracellular fluid volume contraction. Am J Nephrol (1989) 0.97
The effect of ionophore A23187 on calcium ion fluxes and alpha-adrenergic-agonist action in perfused rat liver. Biochem J (1983) 0.97
Characterization of 13 novel band 3 gene defects in hereditary spherocytosis with band 3 deficiency. Blood (1996) 0.97
Diagnostic approach to a patient with hyponatraemia: traditional versus physiology-based options. QJM (2005) 0.97
The sensitivity of the exchange reactions of tricarboxylate, 2-oxoglutarate and dicarboxylate transporting systems of rat liver mitochondria to inhibition by 2-pentylmalonate, p-iodobenzylmalonate, and benzene 1,2,3-tricarboxylate. Eur J Biochem (1971) 0.96
Modulation of the secretion of potassium by accompanying anions in humans. Kidney Int (1991) 0.96
Urine electrolytes and osmolality: when and how to use them. Am J Nephrol (1990) 0.96
Inhibition of enzymes which interact with citrate by (--)hydroxycitrate and 1,2,3,-tricarboxybenzene. Eur J Biochem (1973) 0.95
The inhibition by methylmalonic acid of malate transport by the dicarboxylate carrier in rat liver mitochondria. A possible explantation for hypoglycemia in methylmalonic aciduria. J Clin Invest (1971) 0.94
Disorders of potassium homeostasis: an approach based on pathophysiology. Am J Kidney Dis (1994) 0.93
Role of mucosal IgA in the resistance to Acanthamoeba keratitis. Invest Ophthalmol Vis Sci (1998) 0.93
Regulation of pyruvate dehydrogenase in muscle. Inhibition by citrate. J Biol Chem (1973) 0.92
Lithium-induced impairment of urine acidification. Kidney Int (1976) 0.92
Effects of palmitoyl CoA on citrate and malate transport by rat liver mitochondria. Proc Natl Acad Sci U S A (1972) 0.92
Ammonia addition into the medullary collecting duct of the rat. Kidney Int (1981) 0.91
Relative rates of appearance of nitrogen and sulphur: implications for postprandial synthesis of proteins. Can J Physiol Pharmacol (1993) 0.91
Physiological disposal of the potential alkali load in diet of the rat: steps to achieve acid-base balance. Am J Physiol (1998) 0.91
Intracellular accumulation of free fatty acids in isolated white adipose cells. J Lipid Res (1971) 0.91
Possible mechanisms to explain the absence of hyperkalaemia in Addison's disease. Nephrol Dial Transplant (2001) 0.90
Stimulation of glucose transport in rat adipocytes by insulin, adenosine, nicotinic acid and hydrogen peroxide. Role of adenosine 3':5'-cyclic monophosphate. Biochem J (1979) 0.90
Trifluoperazine, an inhibitor of calmodulin action, antagonises phenylephrine-induced metabolic responses and mitochondrial calcium fluxes in liver. FEBS Lett (1980) 0.90
Mechanism of the diabetogenic action of growth hormone. II. Effect of polypeptides derived from growth hormone on fat metabolism. Biochim Biophys Acta (1969) 0.89
Osmotic demyelination syndrome: a potentially avoidable disaster. QJM (2003) 0.89
Hyponatremia in patients undergoing CAPD: role of water gain and/or malnutrition. Perit Dial Int (2001) 0.89
Permeability of rat adipose tissue mitochondria to citrate, isocitrate and 2-oxoglutarate. Nature (1969) 0.89
Inappropriate secretion of antidiuretic hormone: correction of hyponatremia by expansion of intravascular fluid volume. Can Med Assoc J (1982) 0.89
Regulation of the maximum rate of renal ammoniagenesis in the acidotic dog. Am J Physiol (1985) 0.89
Stimulation of ammonia production and excretion in the rabbit by inorganic phosphate. Study of control mechanisms. J Clin Invest (1976) 0.89
What is responsible for the diurnal variation in potassium excretion? Am J Physiol (1994) 0.89
A physiological analysis of hyponatremia: implications for patients on peritoneal dialysis. Perit Dial Int (2001) 0.89
Insulin therapy in phenformin-associated lactic acidosis; a case report, biochemical considerations and review of the literature. Diabetes (1975) 0.89
Minimum urine flow rate during water deprivation: importance of the permeability of urea in the inner medulla. Kidney Int (1998) 0.88
The urine anion gap: a clinically useful index of ammonium excretion. Am J Med Sci (1986) 0.87
Chronic lactic acidosis in a patient with cancer: therapy and metabolic consequences. Cancer (1981) 0.87
On the role of calcium in the mechanism of action of alpha-adrenergic agonists in rat liver. Pharmacol Ther (1983) 0.87
Studies on the conversion of pyruvate into fatty acids in white adipose tissue. Effects of insulin, alloxan-diabetes and starvation. Biochem J (1971) 0.87
Pathogenesis of acidosis in hereditary fructose intolerance. Metabolism (1979) 0.87
Factors contributing to the degree of polyuria in a patient with poorly controlled diabetes mellitus. Am J Kidney Dis (1997) 0.86
A quantitative analysis of renal ammoniagenesis and energy balance: a theoretical approach. Can J Physiol Pharmacol (1982) 0.86
Effective water clearance and tonicity balance: the excretion of water revisited. Clin Invest Med (1997) 0.86
Protein wasting due to acidosis of prolonged fasting. Am J Physiol (1982) 0.86
The structure and organization of the human erythroid anion exchanger (AE1) gene. Genomics (1994) 0.86
Severe degree of hyperglycaemia: insights from integrative physiology. QJM (2002) 0.86
Metabolic production and renal disposal of hydrogen ions. Kidney Int (1983) 0.86
Regulation of energy metabolism in Morris hepatoma 7777 and 7800. Cancer Res (1981) 0.86
Free fatty acid and ATP levels in adipocytes during lipolysis. Metabolism (1971) 0.86
Can marked hyperglycemia occur without ketosis? Clin Invest Med (1985) 0.86
A new classification for renal defects in net acid excretion. Am J Kidney Dis (1997) 0.85
Prolonged total fasting: a feast for the integrative physiologist. Kidney Int (1998) 0.85
Destruction of erythrocytes in monkeys (Macaca mulatta) infected with Plasmodium cynomolgi. Am J Vet Res (1972) 0.85