Published in FEBS Lett on September 19, 2008
Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development. Proc Natl Acad Sci U S A (2012) 1.03
The awakening of an advanced malignant cancer: an insult to the mitochondrial genome. Biochim Biophys Acta (2011) 1.02
The innate immune system in host mice targets cells with allogenic mitochondrial DNA. J Exp Med (2010) 0.96
Mitochondrial DNA mutations regulate metastasis of human breast cancer cells. PLoS One (2011) 0.95
Metastasis suppressor KISS1 seems to reverse the Warburg effect by enhancing mitochondrial biogenesis. Cancer Res (2013) 0.91
The role of the mitochondrial genome in ageing and carcinogenesis. J Aging Res (2011) 0.90
Regulation of metastasis; mitochondrial DNA mutations have appeared on stage. J Bioenerg Biomembr (2012) 0.82
Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect. Am J Cancer Res (2015) 0.80
Mitochondrial Diseases Part I: mouse models of OXPHOS deficiencies caused by defects in respiratory complex subunits or assembly factors. Mitochondrion (2015) 0.78
Trading mtDNA uncovers its role in metastasis. Cell Adh Migr (2009) 0.77
DNA polymerase beta participates in mitochondrial DNA repair. Mol Cell Biol (2017) 0.76
Interleukin-33 enhances programmed oncosis of ST2L-positive low-metastatic cells in the tumour microenvironment of lung cancer. Cell Death Dis (2016) 0.76
A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNA. PLoS One (2015) 0.76
Administration of an antioxidant prevents lymphoma development in transmitochondrial mice overproducing reactive oxygen species. Exp Anim (2014) 0.75
Retracted Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect. Am J Cancer Res (2015) 0.75
Specific mtDNA mutations in mouse carcinoma cells suppress their tumor formation via activation of the host innate immune system. PLoS One (2013) 0.75
The KISS1 metastasis suppressor appears to reverse the Warburg effect by shifting from glycolysis to mitochondrial beta-oxidation. J Mol Med (Berl) (2017) 0.75
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis. Science (2008) 5.54
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria. Genes Cells (2010) 2.91
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. J Cell Biol (2011) 2.64
The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells. Nat Genet (2007) 2.10
Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation. Proc Natl Acad Sci U S A (2005) 1.82
Reversible regulation of metastasis by ROS-generating mtDNA mutations. Mitochondrion (2008) 1.62
Analysis of the effect of surgical lung biopsy on serum KL-6 Levels in patients with interstitial pneumonia: surgical lung biopsy does not elevate serum KL-6 levels. Intern Med (2006) 1.39
Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells. Hum Mol Genet (2006) 1.32
Mitochondria-related male infertility. Proc Natl Acad Sci U S A (2006) 1.32
New evidence confirms that the mitochondrial bottleneck is generated without reduction of mitochondrial DNA content in early primordial germ cells of mice. PLoS Genet (2009) 1.26
Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAA-ATPase BCS1L. J Cell Sci (2008) 1.21
Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1alpha gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway. J Biol Chem (2009) 1.19
Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells. FEBS Lett (2010) 1.18
Mammalian copper chaperone Cox17p has an essential role in activation of cytochrome C oxidase and embryonic development. Mol Cell Biol (2002) 1.11
MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice. Lipids Health Dis (2012) 1.08
Accumulation of pathogenic DeltamtDNA induced deafness but not diabetic phenotypes in mito-mice. Biochem Biophys Res Commun (2004) 1.06
3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition. Int J Oncol (2007) 1.05
Rare creation of recombinant mtDNA haplotypes in mammalian tissues. Proc Natl Acad Sci U S A (2005) 1.04
Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development. Proc Natl Acad Sci U S A (2012) 1.03
Nuclear DNA but not mtDNA controls tumor phenotypes in mouse cells. Biochem Biophys Res Commun (2005) 1.01
Hydrogen sulfide inhibits hypoxia- but not anoxia-induced hypoxia-inducible factor 1 activation in a von hippel-lindau- and mitochondria-dependent manner. Antioxid Redox Signal (2011) 1.00
Strong evidence of a combination polymorphism of the tyrosine kinase 2 gene and the signal transducer and activator of transcription 3 gene as a DNA-based biomarker for susceptibility to Crohn's disease in the Japanese population. J Clin Immunol (2009) 0.99
Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells. Clin Exp Metastasis (2012) 0.99
Hypoxic induction of hypoxia-inducible factor-1alpha and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells. Biochem Biophys Res Commun (2002) 0.98
Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells. FEBS Lett (2010) 0.97
Deletion-mutant mtDNA increases in somatic tissues but decreases in female germ cells with age. Genetics (2007) 0.97
The innate immune system in host mice targets cells with allogenic mitochondrial DNA. J Exp Med (2010) 0.96
Direct cloning of full-length mouse mitochondrial DNA using a Bacillus subtilis genome vector. Gene (2007) 0.96
Mitochondrial DNA mutations regulate metastasis of human breast cancer cells. PLoS One (2011) 0.95
Methionine aminopeptidase 2 is a new target for the metastasis-associated protein, S100A4. J Biol Chem (2002) 0.93
Mitochondrial dynamics and aging: Mitochondrial interaction preventing individuals from expression of respiratory deficiency caused by mutant mtDNA. Biochim Biophys Acta (2006) 0.92
A case of biatrial multiple myxomas with glandular structure. Ann Thorac Cardiovasc Surg (2007) 0.92
S100A4: a novel negative regulator of mineralization and osteoblast differentiation. J Bone Miner Res (2003) 0.90
A 5-bp insertion in Mip causes recessive congenital cataract in KFRS4/Kyo rats. PLoS One (2012) 0.90
Pathogenic mitochondrial DNA-induced respiration defects in hematopoietic cells result in anemia by suppressing erythroid differentiation. FEBS Lett (2007) 0.88
S100A4 inhibition by RNAi up-regulates osteoblast related genes in periodontal ligament cells. Biochem Biophys Res Commun (2005) 0.86
Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-1alpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor. Cancer Res (2005) 0.85
Over-expression of Tfam improves the mitochondrial disease phenotypes in a mouse model system. Biochem Biophys Res Commun (2010) 0.84
Mitochondrial complex I activity is significantly decreased in a patient with maternally inherited type 2 diabetes mellitus and hypertrophic cardiomyopathy associated with mitochondrial DNA C3310T mutation: a cybrid study. Diabetes Res Clin Pract (2006) 0.84
In vivo interaction between mitochondria carrying mtDNAs from different mouse species. Genetics (2004) 0.84
Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene. Proc Natl Acad Sci U S A (2014) 0.83
MCL-1V, a novel mouse antiapoptotic MCL-1 variant, generated by RNA splicing at a non-canonical splicing pair. Biochem Biophys Res Commun (2009) 0.83
Application of ES cells for generation of respiration-deficient mice carrying mtDNA with a large-scale deletion. Biochem Biophys Res Commun (2005) 0.83
Elevated expression of DNA polymerase kappa in human lung cancer is associated with p53 inactivation: Negative regulation of POLK promoter activity by p53. Int J Oncol (2004) 0.83
Normal mitochondrial respiratory function is essential for spatial remote memory in mice. Mol Brain (2008) 0.83
T-cell-dependent antitumor effects produced by CD40 ligand expressed on mouse lung carcinoma cells are linked with the maturation of dendritic cells and secretion of a variety of cytokines. Cancer Gene Ther (2003) 0.83
Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growth. Angiogenesis (2013) 0.82
Mitochondrial DNA mutations in mutator mice confer respiration defects and B-cell lymphoma development. PLoS One (2013) 0.82
Ditercalinium chloride, a pro-anticancer drug, intimately associates with mammalian mitochondrial DNA and inhibits its replication. Curr Genet (2003) 0.82
A novel function of mtDNA: its involvement in metastasis. Ann N Y Acad Sci (2010) 0.82
Regulation of metastasis; mitochondrial DNA mutations have appeared on stage. J Bioenerg Biomembr (2012) 0.82
Hypoxia-inducible factor-1 mediates the expression of DNA polymerase iota in human tumor cells. Biochem Biophys Res Commun (2006) 0.81
Mitochondrial complementation preventing respiratory dysfunction caused by mutant mtDNA. Biofactors (2009) 0.81
Suppression of disease phenotypes of adult mito-mice carrying pathogenic mtDNA by bone marrow transplantation. Hum Mol Genet (2006) 0.80