Published in Science on January 14, 1977
Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1). Proc Natl Acad Sci U S A (1981) 4.89
Participation of monocyte-macrophages and lymphocytes in the production of a factor that stimulates collagenase and prostaglandin release by rheumatoid synovial cells. J Clin Invest (1979) 3.34
Prostaglandin production by rheumatoid synovial cells: stimulation by a factor from human mononuclear Cells. J Exp Med (1977) 2.47
Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production. J Clin Invest (1980) 2.13
Evidence in support of a self-perpetuating HLA-DR-dependent delayed-type cell reaction in rheumatoid arthritis. Proc Natl Acad Sci U S A (1982) 1.99
Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells. Proc Natl Acad Sci U S A (1987) 1.89
The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor. Biochem J (1983) 1.72
Historical insights into cytokines. Eur J Immunol (2007) 1.71
Human mononuclear cell factors mediate cartilage matrix degradation through chondrocyte activation. J Clin Invest (1981) 1.64
IL-32, a novel cytokine with a possible role in disease. Ann Rheum Dis (2006) 1.54
Purification to homogeneity of pig leucocyte catabolin, a protein that causes cartilage resorption in vitro. Biochem J (1983) 1.54
Collagenase production by rheumatoid synovial cells: morphological and immunohistochemical studies of the dendritic cell. Ann Rheum Dis (1979) 1.50
Proteases induce secretion of collagenase and plasminogen activator by fibroblasts. Proc Natl Acad Sci U S A (1978) 1.40
Regulation of corneal collagenase production: epithelial-stromal cell interactions. Proc Natl Acad Sci U S A (1978) 1.20
Fibroblast prostaglandin E2 synthesis. Persistence of an abnormal phenotype after short-term exposure to mononuclear cell products. J Clin Invest (1983) 1.12
Rat arthritis due to whole group B streptococci. Clinical and histopathologic features compared with groups A and D. Am J Pathol (1983) 1.11
Heberden Oration 1980: aspects of the cell biology of the rheumatoid synovial lesion. Ann Rheum Dis (1981) 1.11
Polymorphonuclear granulocytes in rheumatic tissue destruction. III. an electron microscopic study of PMNs at the pannus-cartilage junction in rheumatoid arthritis. Ann Rheum Dis (1981) 1.09
Regulation of stromal cell collagenase production in adult rabbit cornea: in vitro stimulation and inhibition by epithelial cell products. Proc Natl Acad Sci U S A (1980) 1.09
Inhibition of cartilage breakdown by hydrocortisone in a tissue culture model of rheumatoid arthritis. Ann Rheum Dis (1983) 1.09
Enhanced prostanoid release from monocytes of patients with rheumatoid arthritis and active systemic lupus erythematosus. Ann Rheum Dis (1985) 1.05
Activation of synovial fibroblasts in rheumatoid arthritis. Ann Rheum Dis (1995) 1.03
Interleukin-1 function and role in rheumatic disease. Nat Rev Rheumatol (2015) 1.02
Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis. Arthritis Res Ther (2006) 1.01
The action of human articular-cartilage metalloproteinase on proteoglycan and link protein. Similarities between products of degradation in situ and in vitro. Biochem J (1986) 1.01
Hyperplastic synoviocytes from rats with streptococcal cell wall-induced arthritis exhibit a transformed phenotype that is thymic-dependent and retinoid inhibitable. Am J Pathol (1988) 0.98
Pathology of collagen degradation. A review. Am J Pathol (1978) 0.89
Heparin modulates intracellular cyclic AMP in human trabecular bone cells and adherent rheumatoid synovial cells. Ann Rheum Dis (1984) 0.87
Chemical and immunological features of pleural effusions: comparison between rheumatoid arthritis and other diseases. Thorax (1982) 0.86
Radioimmunoassay of soluble and insoluble collagenases in fibrotic liver. Biochem J (1984) 0.84
Stimulation of production of prostaglandin E in gingival cells exposed to products of human blood mononuclear cells. Biochem J (1981) 0.84
Release of chondrocyte-stimulating factor by rabbit peritoneal macrophages. Clin Exp Immunol (1981) 0.83
Macrophage proteases and rheumatic diseases: regulation of plasminogen activator by thymus-derived lymphocytes. Agents Actions (1978) 0.82
Synovial fluid beta 2 microglobulin and hydroxyproline fractions in rheumatoid arthritis and nonautoimmune arthropathies. Ann Rheum Dis (1980) 0.81
Extracellular hydrolytic enzymes of rabbit dermal tuberculous lesions and tuberculin reactions collected in skin chambers. Am J Pathol (1978) 0.81
Histopathological and ultrastructural studies of synovium in Milwaukee shoulder syndrome--a basic calcium phosphate crystal arthropathy. Ann Rheum Dis (1984) 0.80
The biology of the rheumatoid synovial cell. West J Med (1977) 0.80
Secretion of chondrocyte stimulating factor by macrophages as a result of activation with collagen and proteoglycans. Clin Exp Immunol (1983) 0.79
Cellular control of collagen breakdown in rheumatoid arthritis. Agents Actions (1978) 0.78
2nd International meeting on synovium cell biology, physiology and pathology. Canterbury, United Kingdom, 21-23 September 1994. Proceedings and abstracts. Ann Rheum Dis (1995) 0.75
Rheumatoid synovium: its proliferation, heterogeneity and polarization. West J Med (1977) 0.75
A Brief History of IL-1 and IL-1 Ra in Rheumatology. Front Pharmacol (2017) 0.75
Plasminogen activators and tiaprofenic acid in inflammation. A preliminary study. Drugs (1988) 0.75
British Hypertension Society guidelines for hypertension management 1999: summary. BMJ (1999) 8.80
Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts. J Exp Med (1985) 8.16
Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial. JAMA (1999) 7.37
Respiratory symptoms and atopy in Aberdeen schoolchildren: evidence from two surveys 25 years apart. BMJ (1992) 6.75
Guidelines for management of hypertension: report of the third working party of the British Hypertension Society. J Hum Hypertens (1999) 6.74
Fading of immunofluorescence during microscopy: a study of the phenomenon and its remedy. J Immunol Methods (1982) 5.95
Climate impact of increasing atmospheric carbon dioxide. Science (1981) 5.67
Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells. Proc Natl Acad Sci U S A (1976) 5.40
Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1). Proc Natl Acad Sci U S A (1981) 4.89
Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura. N Engl J Med (1988) 4.69
Isolation of an iron-binding compound from Pseudomonas aeruginosa. J Bacteriol (1979) 4.52
Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum (1990) 4.39
Bulimia nervosa: an ominous variant of anorexia nervosa. Psychol Med (1979) 4.05
CCR5 is characteristic of Th1 lymphocytes. Nature (1998) 3.92
Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis. Arthritis Rheum (1995) 3.83
Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. J Bone Miner Res (1998) 3.65
Psychological therapies for adults with anorexia nervosa: randomised controlled trial of out-patient treatments. Br J Psychiatry (2001) 3.54
Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J Clin Invest (1986) 3.43
Cystic fibrosis in the United Kingdom, 1968-1988: incidence, population and survival. Paediatr Perinat Epidemiol (1993) 3.37
Participation of monocyte-macrophages and lymphocytes in the production of a factor that stimulates collagenase and prostaglandin release by rheumatoid synovial cells. J Clin Invest (1979) 3.34
A heritable disorder of connective tissue. Hydroxylysine-deficient collagen disease. N Engl J Med (1972) 3.32
Specific high-affinity receptors for 1,25-dihydroxyvitamin D3 in human peripheral blood mononuclear cells: presence in monocytes and induction in T lymphocytes following activation. J Clin Endocrinol Metab (1983) 3.27
Fluoride in drinking water and risk of hip fracture in the UK: a case-control study. Lancet (2000) 3.16
Climate response times: dependence on climate sensitivity and ocean mixing. Science (1985) 3.09
Prevalence of headache and migraine in schoolchildren. BMJ (1994) 3.01
Amplification of surface temperature trends and variability in the tropical atmosphere. Science (2005) 2.99
Prevalence of cytolethal distending toxin production in Campylobacter jejuni and relatedness of Campylobacter sp. cdtB gene. Infect Immun (1996) 2.85
Characteristics of sudden death in hemodialysis patients. Kidney Int (2006) 2.80
Concomitant secretion of prourokinase and of a plasminogen activator-specific inhibitor by cultured human monocytes-macrophages. J Exp Med (1984) 2.78
Failed validation of a clinical decision rule for the use of radiography in acute ankle injury. N Z Med J (1994) 2.71
Leflunomide: mode of action in the treatment of rheumatoid arthritis. Ann Rheum Dis (2000) 2.59
Collagenases in human synovial fluid. J Clin Invest (1969) 2.52
Prostaglandin production by rheumatoid synovial cells: stimulation by a factor from human mononuclear Cells. J Exp Med (1977) 2.47
Case reports and confidentiality. Opinion is sought, medical and legal. Br J Psychiatry (1995) 2.46
Studies on collagenase from rheumatoid synovium in tissue culture. J Clin Invest (1968) 2.42
Clonal dominance among T-lymphocyte infiltrates in arthritis. Proc Natl Acad Sci U S A (1988) 2.36
The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix. J Cell Biol (1997) 2.29
Collagenases (third of three parts). N Engl J Med (1974) 2.28
Purification of a factor from human blood monocyte-macrophages which stimulates the production of collagenase and prostaglandin E2 by cells cultured from rheumatoid synovial tissues. FEBS Lett (1981) 2.27
Continuing increase in respiratory symptoms and atopy in Aberdeen schoolchildren. BMJ (1996) 2.27
An endopeptidase from rheumatoid synovial tissue culture. Biochim Biophys Acta (1972) 2.25
Physical exercise and psychological well being: a critical review. Br J Sports Med (1998) 2.25
A urine inhibitor of interleukin 1 activity that blocks ligand binding. J Immunol (1987) 2.17
Family therapy for adolescent anorexia nervosa: the results of a controlled comparison of two family interventions. J Child Psychol Psychiatry (2000) 2.17
Human collagenase: identification and characterization of an enzyme from rheumatoid synovium in culture. Science (1967) 2.15
Incidence, population, and survival of cystic fibrosis in the UK, 1968-95. UK Cystic Fibrosis Survey Management Committee. Arch Dis Child (1997) 2.12
Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis. Cytokine (2000) 2.11
Purification and biologic characterization of a specific tumor necrosis factor alpha inhibitor. J Biol Chem (1989) 2.07
Collagenases (first of three parts). N Engl J Med (1974) 2.06
High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am Rev Respir Dis (1992) 2.05
Pasteurization of Milk Artificially Infected with Two Strains of Brucella suis. J Bacteriol (1932) 2.05
Relation between tumor necrosis factor-alpha and granulocyte elastase-alpha 1-proteinase inhibitor complexes in the plasma of patients with cystic fibrosis. Am Rev Respir Dis (1989) 1.99
Advanced oxidation protein products as novel mediators of inflammation and monocyte activation in chronic renal failure. J Immunol (1998) 1.97
Race, socioeconomic status, and cause-specific mortality. Ann Epidemiol (2000) 1.93
Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes. J Clin Invest (1988) 1.89
Purification and characterization of human interleukin-1 beta expressed in recombinant Escherichia coli. Eur J Biochem (1986) 1.89
A human inhibitor of tumor necrosis factor alpha. J Exp Med (1988) 1.85
Prevalence of asthma and wheeze in the Highlands of Scotland. Arch Dis Child (1994) 1.83
Persistent nocturnal cough in childhood: a population based study. Arch Dis Child (1995) 1.82
Evaluation of social status as a contributing factor to the stroke belt region of the United States. Stroke (1997) 1.81
Antiperinuclear factor and keratin antibodies in rheumatoid arthritis. Ann Rheum Dis (1981) 1.79
Increased prostaglandin production by human monocytes after membrane receptor activation. J Immunol (1979) 1.77
Wheeze, cough, atopy, and indoor environment in the Scottish Highlands. Arch Dis Child (1997) 1.76
Influences of gamma interferon on synovial fibroblast-like cells. Ia induction and inhibition of collagen synthesis. J Clin Invest (1985) 1.71
Synthesis of interleukin 1/endogenous pyrogen in the brain of endotoxin-treated mice: a step in fever induction? J Immunol (1984) 1.71
Prostaglandin E2 and collagenase production by fibroblasts and synovial cells is regulated by urine-derived human interleukin 1 and inhibitor(s). J Clin Invest (1986) 1.70
Allergen immunotherapy: therapeutic vaccines for allergic diseases. World Health Organization. American academy of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol (1998) 1.70
Collagenase production by human synovial tissues. Ann N Y Acad Sci (1975) 1.70
Interleukin 1 is present in normal human epidermis. J Immunol (1986) 1.70
IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes. J Clin Invest (1995) 1.69
Bone resorption induced by parathyroid hormone is strikingly diminished in collagenase-resistant mutant mice. J Clin Invest (1999) 1.67
Medical oaths and declarations. BMJ (2001) 1.67
Induction of human interleukin 1 mRNA measured by collagenase- and prostaglandin E2-stimulating activity in rheumatoid synovial cells. Eur J Immunol (1984) 1.66
Sputum viscosity in cystic fibrosis of the pancreas and other pulmonary diseases. Br J Dis Chest (1970) 1.65
Purified blood monocytes from HIV 1-infected patients produce high levels of TNF alpha and IL-1. Clin Immunol Immunopathol (1989) 1.63
Articular mastocytosis in rheumatoid arthritis. Arthritis Rheum (1984) 1.62
IFN-gamma and 1,25(OH)2D3 induce on THP-1 cells distinct patterns of cell surface antigen expression, cytokine production, and responsiveness to contact with activated T cells. J Immunol (1992) 1.62
Norwegian scabies and a toxic shock syndrome toxin 1-producing strain of Staphylococcus aureus endocarditis in a patient with trisomy 21. Clin Infect Dis (1998) 1.60
Patient preferences for treatment of metastatic breast cancer: a study of women with early-stage breast cancer. J Clin Oncol (1995) 1.60
Inhaled corticosteroids and adrenal insufficiency. Arch Dis Child (2002) 1.58
Generation of collagenase-resistant collagen by site-directed mutagenesis of murine pro alpha 1(I) collagen gene. Proc Natl Acad Sci U S A (1990) 1.57
Anti-intermediate filament antibodies, antikeratin antibody, and antiperinuclear factor in rheumatoid arthritis and infectious mononucleosis. Ann Rheum Dis (1985) 1.57
Modulation of surface antigens of a human monocyte cell line, U937, during incubation with T lymphocyte-conditioned medium: detection of T4 antigen and its presence on normal blood monocytes. J Immunol (1983) 1.57
Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria. Eur J Immunol (1997) 1.56
Differential effects of 1,25-dihydroxyvitamin D3 on human lymphocytes and monocyte/macrophages: inhibition of interleukin-2 and augmentation of interleukin-1 production. Cell Immunol (1986) 1.53
1 alpha,25-dihydroxyvitamin D3 induces maturation of the human monocyte cell line U937, and, in association with a factor from human T lymphocytes, augments production of the monokine, mononuclear cell factor. J Clin Invest (1984) 1.52
Modulation by recombinant interleukin 1 of synthesis of types I and III collagens and associated procollagen mRNA levels in cultured human cells. J Biol Chem (1987) 1.51
Regulation of the mammalian collagenases. Coll Relat Res (1984) 1.49
Pulsed-field gel electrophoresis of degradation-sensitive DNAs from Clostridium difficile PCR ribotype 1 strains. J Clin Microbiol (2000) 1.48
Natural and recombinant human IL-1 receptor antagonists block the effects of IL-1 on bone resorption and prostaglandin production. J Immunol (1990) 1.48
Evaluation of single-leg standing following anterior cruciate ligament surgery and rehabilitation. Phys Ther (1994) 1.47
Macrophage inflammatory protein-1: a prostaglandin-independent endogenous pyrogen. Science (1989) 1.46
Cytokines and other mediators in rheumatoid arthritis. Springer Semin Immunopathol (1984) 1.45