Published in Cell on October 03, 2008
Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol (2009) 7.77
Random versus directionally persistent cell migration. Nat Rev Mol Cell Biol (2009) 4.99
GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote budding. Cell (2009) 2.54
Coordination of Golgi functions by phosphatidylinositol 4-kinases. Trends Cell Biol (2010) 1.64
Pulmonary surfactant: an immunological perspective. Cell Physiol Biochem (2009) 1.34
Orientation and function of the nuclear-centrosomal axis during cell migration. Curr Opin Cell Biol (2011) 1.32
Nonmuscle myosin-2: mix and match. Cell Mol Life Sci (2012) 1.30
The heel and toe of the cell's foot: a multifaceted approach for understanding the structure and dynamics of focal adhesions. Cell Motil Cytoskeleton (2009) 1.29
Surfactant protein A (SP-A)-mediated clearance of Staphylococcus aureus involves binding of SP-A to the staphylococcal adhesin eap and the macrophage receptors SP-A receptor 210 and scavenger receptor class A. J Biol Chem (2010) 1.14
DAAM1 is a formin required for centrosome re-orientation during cell migration. PLoS One (2010) 1.09
Identification of MYO18A as a novel interacting partner of the PAK2/betaPIX/GIT1 complex and its potential function in modulating epithelial cell migration. Mol Biol Cell (2009) 1.07
Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization. J Cell Biol (2013) 1.06
Cytohesin-2/ARNO, through its interaction with focal adhesion adaptor protein paxillin, regulates preadipocyte migration via the downstream activation of Arf6. J Biol Chem (2010) 1.04
Quantitative apical membrane proteomics reveals vasopressin-induced actin dynamics in collecting duct cells. Proc Natl Acad Sci U S A (2013) 0.98
Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment. Proteomics (2012) 0.98
Cdc42-dependent formation of the ZO-1/MRCKβ complex at the leading edge controls cell migration. EMBO J (2011) 0.98
Regulation of IRSp53-dependent filopodial dynamics by antagonism between 14-3-3 binding and SH3-mediated localization. Mol Cell Biol (2009) 0.94
A regulatory motif in nonmuscle myosin II-B regulates its role in migratory front-back polarity. J Cell Biol (2015) 0.94
A migration signature and plasma biomarker panel for pancreatic adenocarcinoma. Cancer Prev Res (Phila) (2010) 0.91
Mammalian myosin-18A, a highly divergent myosin. J Biol Chem (2013) 0.91
The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity. PLoS One (2015) 0.88
Molecular pathways: targeting the kinase effectors of RHO-family GTPases. Clin Cancer Res (2014) 0.86
Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARγ-targeted therapy. Oncogene (2012) 0.84
Drosophila melanogaster myosin-18 represents a highly divergent motor with actin tethering properties. J Biol Chem (2011) 0.84
Myotonic dystrophy kinase-related Cdc42-binding kinases (MRCK), the ROCK-like effectors of Cdc42 and Rac1. Small GTPases (2015) 0.83
Mouse myosin-19 is a plus-end-directed, high-duty ratio molecular motor. J Biol Chem (2014) 0.82
Proteomics analysis of the ezrin interactome in B cells reveals a novel association with Myo18aα. J Proteome Res (2011) 0.82
Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3. J Biol Chem (2013) 0.81
A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection. Cell Syst (2016) 0.81
Myosin light chain kinases: division of work in cell migration. Cell Adh Migr (2009) 0.80
The PAKs come of age: Celebrating 18 years of discovery. Cell Logist (2012) 0.80
The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer. J Mol Med (Berl) (2014) 0.80
Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex. Proc Natl Acad Sci U S A (2013) 0.79
Four things to know about myosin light chains as reporters for non-muscle myosin-2 dynamics in live cells. Cytoskeleton (Hoboken) (2015) 0.78
PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction. J Cell Biol (2014) 0.78
Life without double-headed non-muscle myosin II motor proteins. Front Chem (2014) 0.78
A novel small-molecule MRCK inhibitor blocks cancer cell invasion. Cell Commun Signal (2014) 0.78
Arg kinase-binding protein 2 (ArgBP2) interaction with α-actinin and actin stress fibers inhibits cell migration. J Biol Chem (2014) 0.78
Myosin light chains: Teaching old dogs new tricks. Bioarchitecture (2014) 0.77
DOCK8 Regulates Macrophage Migration through Cdc42 Activation and LRAP35a Interaction. J Biol Chem (2016) 0.77
The ezrin-radixin-moesin family of proteins in the regulation of B-cell immune response. Crit Rev Immunol (2015) 0.76
Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics. J Biol Chem (2014) 0.76
SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation. PLoS One (2015) 0.76
LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration. Mol Biol Cell (2017) 0.75
The Zebrafish frozen Mutant Is a Model for Human Myopathy Associated with Mutation of the Unconventional Myosin MYO18B. Genetics (2016) 0.75
Coiled-coils: The long and short of it. Bioessays (2016) 0.75
Functional Genomics Identifies Tis21-Dependent Mechanisms and Putative Cancer Drug Targets Underlying Medulloblastoma Shh-Type Development. Front Pharmacol (2016) 0.75
Identification of novel MYO18A interaction partners required for myoblast adhesion and muscle integrity. Sci Rep (2016) 0.75
Myosin B of Plasmodium falciparum (PfMyoB): in silico prediction of its three-dimensional structure and its possible interaction with MTIP. Parasitol Res (2017) 0.75
Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: a randomized trial. JAMA (2010) 4.71
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol Cell (2005) 2.11
PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition. Cancer Res (2007) 2.03
Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse. J Neurosci (2004) 1.66
Raf-1 regulates Rho signaling and cell migration. J Cell Biol (2005) 1.58
Detection of the siphon internal carotid artery stenosis: transcranial Doppler versus digital subtraction angiography. J Neuroimaging (2009) 1.38
The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family. Curr Biol (2002) 1.30
PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway. J Biol Chem (2008) 1.24
Characterization of RhoA-binding kinase ROKalpha implication of the pleckstrin homology domain in ROKalpha function using region-specific antibodies. J Biol Chem (2002) 1.22
Phosphorylation and reorganization of vimentin by p21-activated kinase (PAK). Genes Cells (2002) 1.22
CaMKII phosphorylates collapsin response mediator protein 2 and modulates axonal damage during glutamate excitotoxicity. J Neurochem (2009) 1.14
GIT1 activates p21-activated kinase through a mechanism independent of p21 binding. Mol Cell Biol (2004) 1.13
IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner. J Biol Chem (2005) 1.13
Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2. J Biol Chem (2009) 1.13
Treatment for hepatocellular carcinoma with portal vein tumor thrombosis: the emerging role for radioembolization using yttrium-90. Oncology (2013) 1.12
Mypt1-mediated spatial positioning of Bmp2-producing cells is essential for liver organogenesis. Development (2008) 1.10
DAAM1 is a formin required for centrosome re-orientation during cell migration. PLoS One (2010) 1.09
Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation. J Biol Chem (2013) 1.08
Rho-mediated assembly of stress fibers is differentially regulated in corneal fibroblasts and myofibroblasts. Exp Cell Res (2004) 1.07
SNX9 as an adaptor for linking synaptojanin-1 to the Cdc42 effector ACK1. FEBS Lett (2005) 1.05
Paxillin nuclear-cytoplasmic localization is regulated by phosphorylation of the LD4 motif: evidence that nuclear paxillin promotes cell proliferation. Biochem J (2009) 1.05
ArhGAP15, a novel human RacGAP protein with GTPase binding property. FEBS Lett (2003) 1.03
From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-alpha kinase activity. J Cell Biol (2009) 1.01
Geographic and sex difference in the distribution of intracranial atherosclerosis in China. Stroke (2013) 0.99
A functional requirement for PAK1 binding to the KH(2) domain of the fragile X protein-related FXR1. Mol Cell (2010) 0.99
Vimentin intermediate filament reorganization by Cdc42: involvement of PAK and p70 S6 kinase. Eur J Cell Biol (2002) 0.97
Phosphorylation of myosin phosphatase targeting subunit 3 (MYPT3) and regulation of protein phosphatase 1 by protein kinase A. J Biol Chem (2006) 0.94
Signal intensity ratio as a novel measure of hemodynamic significance for intracranial atherosclerosis. Int J Stroke (2013) 0.94
Outgrowth of neurites from NIE-115 neuroblastoma cells is prevented on repulsive substrates through the action of PAK. Mol Cell Biol (2005) 0.92
Long-term prognosis of Chinese patients with a lacunar infarct associated with small vessel disease: a five-year longitudinal study. Int J Stroke (2009) 0.90
The Drosophila homologue of Arf-GAP GIT1, dGIT, is required for proper muscle morphogenesis and guidance during embryogenesis. Dev Biol (2008) 0.90
ACK family tyrosine kinase activity is a component of Dcdc42 signaling during dorsal closure in Drosophila melanogaster. Mol Cell Biol (2002) 0.90
p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology. FEBS Lett (2002) 0.90
Interobserver reproducibility of signal intensity ratio on magnetic resonance angiography for hemodynamic impact of intracranial atherosclerosis. J Stroke Cerebrovasc Dis (2013) 0.90
Magnetic resonance angiography signal intensity as a marker of hemodynamic impairment in intracranial arterial stenosis. PLoS One (2013) 0.89
Evaluation of age-related white matter changes using transcranial Doppler ultrasonography. J Neuroimaging (2011) 0.88
Functional interactions between phosphatase POPX2 and mDia modulate RhoA pathways. J Cell Sci (2008) 0.88
Drac1 and Crumbs participate in amnioserosa morphogenesis during dorsal closure in Drosophila. J Cell Sci (2002) 0.87
Preliminary findings of the effects of autonomic dysfunction on functional outcome after acute ischemic stroke. Clin Neurol Neurosurg (2011) 0.86
Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase. FEBS Lett (2011) 0.86
Characteristics of patients with abnormal glucose challenge test and normal oral glucose tolerance test results: comparison with normal and gestational diabetic patients. Am J Obstet Gynecol (2006) 0.85
dPak is required for integrity of the leading edge cytoskeleton during Drosophila dorsal closure but does not signal through the JNK cascade. Dev Biol (2004) 0.85
Selection of aptamers for signal transduction proteins by capillary electrophoresis. Electrophoresis (2010) 0.84
C1, see them all. Trends Biochem Sci (2005) 0.84
Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) on myosin light chain phosphorylation. Eur J Cell Biol (2002) 0.83
Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding. J Biol Chem (2004) 0.81
Myosin light chain kinases: division of work in cell migration. Cell Adh Migr (2009) 0.80
Cerebral Microbleeds and Cognitive Function in Ischemic Stroke or Transient Ischemic Attack Patients. Dement Geriatr Cogn Disord (2015) 0.77
Molecular aptamer beacon for myotonic dystrophy kinase-related Cdc42-binding kinase alpha. Talanta (2010) 0.76
Rivastigmine in Chinese patients with subcortical vascular dementia. Neuropsychiatr Dis Treat (2007) 0.76
Comparison of carotid atherosclerotic plaque characteristics between patients with first-time and recurrent acute ischaemic stroke using B-mode ultrasound. Neurol Res (2015) 0.75
Embolic Doppler ultrasound signal detection using continuous wavelet transform to detect multiple vascular emboli. J Neuroimaging (2008) 0.75
A Ras-based module to generate 32P-labeled fusion proteins for blot overlays. Methods Mol Biol (2002) 0.75
Introduction of dominant inhibitory proteins directed against ROK and MRCK kinases. Methods Mol Biol (2002) 0.75