Published in J Biol Chem on January 15, 1991
Braf(V600E) cooperates with Pten loss to induce metastatic melanoma. Nat Genet (2009) 7.81
A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase. EMBO J (1992) 2.51
Regulated bidirectional motility of melanophore pigment granules along microtubules in vitro. Proc Natl Acad Sci U S A (1997) 2.42
A model for melanosome biogenesis based on the purification and analysis of early melanosomes. Proc Natl Acad Sci U S A (2001) 2.06
Copper active sites in biology. Chem Rev (2014) 1.90
Immune response to a differentiation antigen induced by altered antigen: a study of tumor rejection and autoimmunity. Proc Natl Acad Sci U S A (1996) 1.85
Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis. EMBO J (1994) 1.71
Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells. Proc Natl Acad Sci U S A (1997) 1.61
Mutation in and lack of expression of tyrosinase-related protein-1 (TRP-1) in melanocytes from an individual with brown oculocutaneous albinism: a new subtype of albinism classified as "OCA3". Am J Hum Genet (1996) 1.59
Immunophenotyping of melanomas for tyrosinase: implications for vaccine development. Proc Natl Acad Sci U S A (1995) 1.48
Melanophilin, the product of the leaden locus, is required for targeting of myosin-Va to melanosomes. Traffic (2002) 1.34
Pink-eyed dilution protein controls the processing of tyrosinase. Mol Biol Cell (2002) 1.29
The ocular albinism type 1 gene product is a membrane glycoprotein localized to melanosomes. Proc Natl Acad Sci U S A (1996) 1.28
Rufous oculocutaneous albinism in southern African Blacks is caused by mutations in the TYRP1 gene. Am J Hum Genet (1997) 1.23
Identification of a melanosomal matrix protein encoded by the murine si (silver) locus using "organelle scanning". Proc Natl Acad Sci U S A (1994) 1.20
Beta-catenin activity in the dermal papilla of the hair follicle regulates pigment-type switching. Proc Natl Acad Sci U S A (2010) 1.19
Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function. Mol Cell Biol (1994) 1.14
Rab8 regulates the actin-based movement of melanosomes. Mol Biol Cell (2005) 1.03
Identification of morc (microrchidia), a mutation that results in arrest of spermatogenesis at an early meiotic stage in the mouse. Proc Natl Acad Sci U S A (1998) 1.02
A single base insertion in the putative transmembrane domain of the tyrosinase gene as a cause for tyrosinase-negative oculocutaneous albinism. Proc Natl Acad Sci U S A (1991) 1.01
Nitric oxide produced by ultraviolet-irradiated keratinocytes stimulates melanogenesis. J Clin Invest (1997) 1.01
Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation. PLoS Genet (2011) 0.97
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase. Biochem J (2001) 0.96
Involvement of dynein and spectrin with early melanosome transport and melanosomal protein trafficking. J Invest Dermatol (2007) 0.96
Generation of polyclonal rabbit antisera to mouse melanoma associated antigens using gene gun immunization. J Immunol Methods (1998) 0.95
Intracellular composition of fatty acid affects the processing and function of tyrosinase through the ubiquitin-proteasome pathway. Biochem J (2006) 0.94
Identification of quinolines that inhibit melanogenesis by altering tyrosinase family trafficking. Mol Pharmacol (2008) 0.93
5,6-Dihydroxyindole-2-carboxylic acid is incorporated in mammalian melanin. Biochem J (1992) 0.90
Changes in expression of putative antigens encoded by pigment genes in mouse melanomas at different stages of malignant progression. Proc Natl Acad Sci U S A (1995) 0.89
The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes. Mol Biol Cell (2011) 0.88
Involvement of the tyrosinase gene in the deposition of cardiac lipofuscin in mice. Association with aortic fatty streak development. J Clin Invest (1993) 0.87
New insights into the evolution of metazoan tyrosinase gene family. PLoS One (2012) 0.86
Complete sequence and polymorphism study of the human TYRP1 gene encoding tyrosinase-related protein 1. Mamm Genome (1998) 0.85
Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells. Biochem J (1999) 0.85
Mammalian tyrosinase-related protein-1 is recognized by autoantibodies from vitiliginous Smyth chickens. An avian model for human vitiligo. Am J Pathol (1995) 0.84
Subcellular localization and function of melanogenic enzymes in the ink gland of Sepia officinalis. Biochem J (1997) 0.78
Essential role of the molecular chaperone gp96 in regulating melanogenesis. Pigment Cell Melanoma Res (2013) 0.77
Differential expression of TYRP1 in adult human retinal pigment epithelium and uveal melanoma cells. Oncol Lett (2016) 0.75
Cross-talk between Dopachrome Tautomerase and Caveolin-1 Is Melanoma Cell Phenotype-specific and Potentially Involved in Tumor Progression. J Biol Chem (2016) 0.75
A novel approach to enhance antibody sensitivity and specificity by peptide cross-linking. Anal Biochem (2008) 0.75
T cell tolerance to the skin: a central role for central tolerance. Semin Immunopathol (2007) 0.75
An improved colorimetric assay for interleukin 2. J Immunol Methods (1986) 3.39
Biochemical studies of phenoloxidase and utilization of catecholamines in Cryptococcus neoformans. J Bacteriol (1982) 2.98
Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice. Circulation (1999) 2.84
A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase. EMBO J (1992) 2.51
Enzymatic control of pigmentation in mammals. FASEB J (1991) 2.47
Autocrine saturation of pro-urokinase receptors on human A431 cells. Cell (1986) 2.38
A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus. EMBO J (1992) 2.19
A model for melanosome biogenesis based on the purification and analysis of early melanosomes. Proc Natl Acad Sci U S A (2001) 2.06
Treatment of reticulate acropigmentation of Kitamura with azelaic acid. An immunohistochemical and electron microscopic study. J Am Acad Dermatol (1992) 1.84
Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities. Nat Genet (1999) 1.75
Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis. EMBO J (1994) 1.71
What are melanocytes really doing all day long...? Exp Dermatol (2009) 1.65
The Pmel 17/silver locus protein. Characterization and investigation of its melanogenic function. J Biol Chem (1994) 1.65
Mutation in and lack of expression of tyrosinase-related protein-1 (TRP-1) in melanocytes from an individual with brown oculocutaneous albinism: a new subtype of albinism classified as "OCA3". Am J Hum Genet (1996) 1.59
Mammalian tyrosinase. A comparison of tyrosine hydroxylation and melanin formation. Biochem J (1976) 1.59
Characterization of eight beta-lactamases of Gram-negative bacteria. J Bacteriol (1982) 1.57
A new enzymatic function in the melanogenic pathway. The 5,6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1). J Biol Chem (1994) 1.56
Treatment of plasma cell cheilitis with griseofulvin. J Am Acad Dermatol (1994) 1.52
Habitat segregation and biochemical activities of marine members of the family vibrionaceae. Appl Environ Microbiol (1985) 1.51
Carbenicillin-hydrolyzing penicillinases of Proteus mirabilis and the PSE-type penicillinases of Pseudomonas aeruginosa. Microbiol Immunol (1983) 1.47
Modulation of melanogenic protein expression during the switch from eu- to pheomelanogenesis. J Cell Sci (1995) 1.45
Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides. Proc Natl Acad Sci U S A (1995) 1.42
Nucleotide sequence and characterization of a carbenicillin-hydrolyzing penicillinase gene from Proteus mirabilis. J Bacteriol (1991) 1.41
Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B. J Lipid Res (1999) 1.40
Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells. Biochem Biophys Res Commun (2001) 1.39
A novel GATA4 mutation completely segregated with atrial septal defect in a large Japanese family. J Med Genet (2004) 1.37
Encephalitis and retarded growth of chicks caused by Sitiawan virus, a new isolate belonging to the genus Flavivirus. Am J Trop Med Hyg (2001) 1.35
Oculocutaneous albinism types 1 and 3 are ER retention diseases: mutation of tyrosinase or Tyrp1 can affect the processing of both mutant and wild-type proteins. FASEB J (2001) 1.33
Genetic analysis of type E botulinum toxin-producing Clostridium butyricum strains. Appl Environ Microbiol (2000) 1.32
The molecular basis of oculocutaneous albinism type 1 (OCA1): sorting failure and degradation of mutant tyrosinases results in a lack of pigmentation. Biochem J (2001) 1.30
The inherent cytotoxicity of melanin precursors: a revision. Biochim Biophys Acta (1994) 1.29
Expression of aromatase cytochrome P450 protein and messenger ribonucleic acid in human endometriotic and adenomyotic tissues but not in normal endometrium. Biol Reprod (1997) 1.27
Mammalin tyrosinase. Stoichiometry and measurement of reaction products. Biochim Biophys Acta (1980) 1.27
Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to alpha-melanotropin. J Invest Dermatol (1997) 1.26
Mammalian monophenol monooxygenase (tyrosinase): purification, properties, and reactions catalyzed. Methods Enzymol (1987) 1.26
Tyrosinase stabilization by Tyrp1 (the brown locus protein). J Biol Chem (1998) 1.24
Reduction of isoprostanes and regression of advanced atherosclerosis by apolipoprotein E. J Biol Chem (2001) 1.23
Identification of a melanosomal matrix protein encoded by the murine si (silver) locus using "organelle scanning". Proc Natl Acad Sci U S A (1994) 1.20
Thiazolidinediones suppress endothelin-1 secretion from bovine vascular endothelial cells: a new possible role of PPARgamma on vascular endothelial function. Biochem Biophys Res Commun (1999) 1.19
Excitatory amino acids in the rostral ventrolateral medulla support blood pressure in spontaneously hypertensive rats. Hypertension (2000) 1.19
Identification of a genetic determinant of pathogenicity in chicken anaemia virus. J Gen Virol (2001) 1.19
A mitogenomic perspective on the basal teleostean phylogeny: resolving higher-level relationships with longer DNA sequences. Mol Phylogenet Evol (2001) 1.17
Influence of water temperature and feeding regime on otolith growth in Anguilla japonica glass eels and elvers: does otolith growth cease at low temperatures? J Fish Biol (2009) 1.17
Mutational mapping of the catalytic activities of human tyrosinase. J Biol Chem (1992) 1.17
The tyrosinase gene family--interactions of melanogenic proteins to regulate melanogenesis. Cell Mol Biol Res (1994) 1.17
The fine structure of melanogenesis in coat color mutants of the mouse. J Ultrastruct Res (1973) 1.16
Anti-T4-tyrosinase monoclonal antibodies--specific markers for pigmented melanocytes. J Invest Dermatol (1985) 1.15
Pathology of fatal highly pathogenic H5N1 avian influenza virus infection in large-billed crows (Corvus macrorhynchos) during the 2004 outbreak in Japan. Vet Pathol (2006) 1.14
Cefoxitin, N-formimidoyl thienamycin, clavulanic acid, and penicillanic acid sulfone as suicide inhibitors for different types of beta-lactamases produced by gram-negative bacteria. J Antibiot (Tokyo) (1982) 1.13
Mammalian tyrosinase. Structural and functional interraltionship of isozymes. Biochim Biophys Acta (1978) 1.13
Endogenous acyl ghrelin is involved in mediating spontaneous phase III-like contractions of the rat stomach. Neurogastroenterol Motil (2007) 1.12
The melanocortin-1 receptor is a key regulator of human cutaneous pigmentation. Pigment Cell Res (2000) 1.11
Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis. J Clin Invest (2001) 1.11
Imported parakeets harbor H9N2 influenza A viruses that are genetically closely related to those transmitted to humans in Hong Kong. J Virol (2001) 1.11
A set of bacterial strains for evaluation of beta-lactamase-stability of beta-lactam antibiotics. J Antibiot (Tokyo) (1981) 1.10
Mammalian tyrosinase: biosynthesis, processing, and modulation by melanocyte-stimulating hormone. Proc Natl Acad Sci U S A (1988) 1.09
Specific identification of an authentic clone for mammalian tyrosinase. J Biol Chem (1989) 1.08
A standardized protocol for assessing regulators of pigmentation. Anal Biochem (1999) 1.07
Tyrosinase activity in subcellular fractions of black and albino mice. Nat New Biol (1973) 1.07
Inhibitors of mammalian melanocyte tyrosinase: in vitro comparisons of alkyl esters of gentisic acid with other putative inhibitors. Biochem Pharmacol (1999) 1.07
Avian nephritis virus (ANV) as a new member of the family Astroviridae and construction of infectious ANV cDNA. J Virol (2000) 1.07
Unraveling the melanocyte. Am J Hum Genet (1993) 1.07
Expression of human scavenger receptor class B type I in cultured human monocyte-derived macrophages and atherosclerotic lesions. Circ Res (1999) 1.06
Possible involvement of proteolytic degradation of tyrosinase in the regulatory effect of fatty acids on melanogenesis. J Lipid Res (1999) 1.05
New regulators of melanogenesis are associated with purified tyrosinase isozymes. J Invest Dermatol (1982) 1.05
Hepatic apolipoprotein E expression promotes very low density lipoprotein-apolipoprotein B production in vivo in mice. J Lipid Res (2000) 1.05
A distant evolutionary relationship between bacterial sphingomyelinase and mammalian DNase I. Protein Sci (1996) 1.04
Sympatric spawning of Anguilla marmorata and Anguilla japonica in the western North Pacific Ocean. J Fish Biol (2009) 1.04
Production of melanocyte-specific antibodies to human melanosomal proteins: expression patterns in normal human skin and in cutaneous pigmented lesions. Pigment Cell Res (2001) 1.03
Expression of leptin receptor in human endometrium and fluctuation during the menstrual cycle. J Clin Endocrinol Metab (2000) 1.03
Regulation of melanogenesis through phosphatidylinositol 3-kinase-Akt pathway in human G361 melanoma cells. J Invest Dermatol (2000) 1.03
Biochemical studies on bovine adenovirus type 3. I. Purification and properties. J Virol (1975) 1.03
Melanin biosynthesis patterns following hormonal stimulation. J Biol Chem (1993) 1.02
Two distinct class II molecules encoded by the genes within HLA-DR subregion of HLA-Dw2 and Dw12 can act as stimulating and restriction molecules. J Immunol (1985) 1.02
Leptin directly stimulates aromatase activity in human luteinized granulosa cells. Mol Hum Reprod (1999) 1.02
Tonic excitatory input to the rostral ventrolateral medulla in Dahl salt-sensitive rats. Hypertension (2001) 1.02
Melanosomal proteins as melanoma-specific immune targets. Melanoma Res (1997) 1.01
Potent and preferential inhibition of Ca2+/calmodulin-dependent protein kinase II by K252a and its derivative, KT5926. Biochem Biophys Res Commun (1991) 1.01
The Anguilla spp. migration problem: 40 million years of evolution and two millennia of speculation. J Fish Biol (2012) 1.00
Enzyme activity of macrophage migration inhibitory factor toward oxidized catecholamines. J Biol Chem (1999) 0.99
Characterization of genes modulated during pheomelanogenesis using differential display. Proc Natl Acad Sci U S A (1998) 0.99
Leiomyosarcoma of the bladder eighteen years after cyclophosphamide therapy for retinoblastoma. Urol Int (1993) 0.99
The expression of tyrosinase, tyrosinase-related proteins 1 and 2 (TRP1 and TRP2), the silver protein, and a melanogenic inhibitor in human melanoma cells of differing melanogenic activities. Pigment Cell Res (1995) 0.98
Mammalian tyrosinase: isozymic forms of the enzyme. Int J Biochem (1981) 0.97
Cloning and sequencing of an Na+/H+ antiporter gene from the marine bacterium Vibrio alginolyticus. Biochim Biophys Acta (1994) 0.97
Dynamics of pigmentation induction by repeated ultraviolet exposures: dose, dose interval and ultraviolet spectrum dependence. Br J Dermatol (2008) 0.97
The melanocortin 1 receptor is the principal mediator of the effects of agouti signaling protein on mammalian melanocytes. J Cell Sci (2001) 0.96
Modulation of murine melanocyte function in vitro by agouti signal protein. EMBO J (1997) 0.96
Amino acid sequence, active-site residue, and effect of suicide inhibitors on cephalosporinase of Citrobacter freundii GN346. Rev Infect Dis (1988) 0.96
Translation of interleukin 2 mRNA from human peripheral blood leukocytes in Xenopus oocytes. Biochem Biophys Res Commun (1982) 0.96
Functional properties of cloned melanogenic proteins. Pigment Cell Res (1992) 0.96
Pigment production in murine melanoma cells is regulated by tyrosinase, tyrosinase-related protein 1 (TRP1), DOPAchrome tautomerase (TRP2), and a melanogenic inhibitor. J Invest Dermatol (1993) 0.95
Spectroscopic and kinetic studies on reaction of cytochrome P450nor with nitric oxide. Implication for its nitric oxide reduction mechanism. J Biol Chem (1995) 0.95
Differentiation and the tumorigenic and metastatic phenotype of murine melanoma cells. Int J Cancer (1990) 0.94
Characteristics of murine non-specific killer cells induced in vivo by recombinant human interleukin-2. Immunology (1986) 0.94
Involvement of ITF2 in the transcriptional regulation of melanogenic genes. J Biol Chem (2001) 0.94