William C Skarnes

Author PubWeight™ 73.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The knockout mouse project. Nat Genet 2004 7.80
2 BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res 2003 4.83
3 A public gene trap resource for mouse functional genomics. Nat Genet 2004 3.96
4 Agouti C57BL/6N embryonic stem cells for mouse genetic resources. Nat Methods 2009 3.68
5 Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell 2013 3.47
6 The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res 2006 3.40
7 The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium. Nucleic Acids Res 2010 3.23
8 ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. Proc Natl Acad Sci U S A 2008 3.15
9 The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome 2012 2.65
10 Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. Nat Cell Biol 2010 2.55
11 The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice. Development 2004 2.45
12 The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res 2013 2.20
13 Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project. Mamm Genome 2012 2.12
14 Dual RMCE for efficient re-engineering of mouse mutant alleles. Nat Methods 2010 2.05
15 Polybromo protein BAF180 functions in mammalian cardiac chamber maturation. Genes Dev 2004 1.93
16 Extensive genomic copy number variation in embryonic stem cells. Proc Natl Acad Sci U S A 2008 1.91
17 Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev 2005 1.65
18 Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans. Mamm Genome 2012 1.63
19 Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice. J Clin Invest 2011 1.59
20 Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers. Mol Cell Biol 2005 1.46
21 The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development. Proc Natl Acad Sci U S A 2005 1.44
22 ATP-citrate lyase deficiency in the mouse. J Biol Chem 2003 1.35
23 Gene structure and functional analysis of the mouse nidogen-2 gene: nidogen-2 is not essential for basement membrane formation in mice. Mol Cell Biol 2002 1.12
24 Floxin, a resource for genetically engineering mouse ESCs. Nat Methods 2009 1.07
25 Maternal effect for DNA mismatch repair in the mouse. Genetics 2002 1.02
26 MiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs. PLoS One 2012 0.99
27 Defining the importance of phosphatidylserine synthase 2 in mice. J Biol Chem 2002 0.99
28 BioMart as an integration solution for the International Knockout Mouse Consortium. Database (Oxford) 2011 0.96
29 Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource. Mamm Genome 2013 0.96
30 Embryonic fibroblasts with a gene trap mutation in Ext1 produce short heparan sulfate chains. J Biol Chem 2004 0.96
31 Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells. PLoS One 2007 0.95
32 Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques. Genesis 2003 0.89
33 Beta1,3-N-acetylglucosaminyltransferase 1 glycosylation is required for axon pathfinding by olfactory sensory neurons. J Neurosci 2005 0.88
34 JAM-A expression during embryonic development. Dev Dyn 2005 0.83
35 Bi-allelic gene targeting in mouse embryonic stem cells. Methods 2011 0.83
36 Large-scale identification of microRNA targets in murine Dgcr8-deficient embryonic stem cell lines. PLoS One 2012 0.80
37 Gene trapping in mouse embryonic stem cells. Methods Mol Biol 2008 0.78
38 Building and sharing resources. Interview by Krystie Nybo. Biotechniques 2012 0.75