Human papillomavirus molecular biology and disease association.

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🔗 View Article (PMID 25752814)

Published in Rev Med Virol on March 01, 2015

Authors

John Doorbar1, Nagayasu Egawa, Heather Griffin, Christian Kranjec, Isao Murakami

Author Affiliations

1: Department of Pathology, University of Cambridge, Cambridge, UK.

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Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature (1996) 3.61

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Human papillomavirus types in 115,789 HPV-positive women: a meta-analysis from cervical infection to cancer. Int J Cancer (2012) 3.35

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Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm. J Virol (1991) 3.10

Integration of human papillomavirus type 16 DNA into the human genome leads to increased stability of E6 and E7 mRNAs: implications for cervical carcinogenesis. Proc Natl Acad Sci U S A (1995) 2.79

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Verrucous cyst. Arch Dermatol (1991) 1.40

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