Published in J Nutr on December 01, 2008
Biotinylation is a natural, albeit rare, modification of human histones. Mol Genet Metab (2011) 1.77
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Novel histone biotinylation marks are enriched in repeat regions and participate in repression of transcriptionally competent genes. J Nutr Biochem (2010) 1.36
Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18. J Nutr Biochem (2010) 1.17
K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts. J Nutr Biochem (2009) 1.15
The role of histone H4 biotinylation in the structure of nucleosomes. PLoS One (2011) 1.01
N- and C-terminal domains in human holocarboxylase synthetase participate in substrate recognition. Mol Genet Metab (2009) 0.99
Biotin requirements are lower in human Jurkat lymphoid cells but homeostatic mechanisms are similar to those of HepG2 liver cells. J Nutr (2010) 0.96
Biotin regulates the expression of holocarboxylase synthetase in the miR-539 pathway in HEK-293 cells. J Nutr (2010) 0.94
K16-biotinylated histone H4 is overrepresented in repeat regions and participates in the repression of transcriptionally competent genes in human Jurkat lymphoid cells. J Nutr Biochem (2011) 0.94
Repression of transposable elements by histone biotinylation. J Nutr (2009) 0.93
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Holocarboxylase synthetase interacts physically with euchromatic histone-lysine N-methyltransferase, linking histone biotinylation with methylation events. J Nutr Biochem (2013) 0.91
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Effects of single-nucleotide polymorphisms in the human holocarboxylase synthetase gene on enzyme catalysis. Eur J Hum Genet (2011) 0.90
Holocarboxylase synthetase synergizes with methyl CpG binding protein 2 and DNA methyltransferase 1 in the transcriptional repression of long-terminal repeats. Epigenetics (2013) 0.89
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Human holocarboxylase synthetase with a start site at methionine-58 is the predominant nuclear variant of this protein and has catalytic activity. Biochem Biophys Res Commun (2011) 0.87
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Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells. J Nutr Biochem (2011) 0.84
Three promoters regulate the transcriptional activity of the human holocarboxylase synthetase gene. J Nutr Biochem (2013) 0.84
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Biotinylation of lysine 16 in histone H4 contributes toward nucleosome condensation. Arch Biochem Biophys (2012) 0.83
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The polypeptide Syn67 interacts physically with human holocarboxylase synthetase, but is not a target for biotinylation. Arch Biochem Biophys (2009) 0.80
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Resveratrol compounds inhibit human holocarboxylase synthetase and cause a lean phenotype in Drosophila melanogaster. J Nutr Biochem (2015) 0.75
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Expression of oncogenes depends on biotin in human small cell lung cancer cells NCI-H69. Int J Vitam Nutr Res (2003) 0.98
Urinary biotin analogs increase in humans during chronic supplementation: the analogs are biotin metabolites. Am J Physiol (1997) 0.95
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K8 and K12 are biotinylated in human histone H4. Eur J Biochem (2004) 2.02
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Lysine residues in N-terminal and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase. J Nutr Biochem (2005) 1.88
K4, K9 and K18 in human histone H3 are targets for biotinylation by biotinidase. FEBS J (2005) 1.84
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Biotinylation is a natural, albeit rare, modification of human histones. Mol Genet Metab (2011) 1.77
Postnatal human herpesvirus 8 and human immunodeficiency virus type 1 infection in mothers and infants from Zambia. J Infect Dis (2003) 1.74
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K12-biotinylated histone H4 marks heterochromatin in human lymphoblastoma cells. J Nutr Biochem (2007) 1.64
Biotin supply affects expression of biotin transporters, biotinylation of carboxylases and metabolism of interleukin-2 in Jurkat cells. J Nutr (2002) 1.62
Holocarboxylase synthetase regulates expression of biotin transporters by chromatin remodeling events at the SMVT locus. J Nutr Biochem (2007) 1.57
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Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3. BMB Rep (2008) 1.40
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Novel histone biotinylation marks are enriched in repeat regions and participate in repression of transcriptionally competent genes. J Nutr Biochem (2010) 1.36
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Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18. J Nutr Biochem (2010) 1.17
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K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts. J Nutr Biochem (2009) 1.15
The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells. J Nutr (2003) 1.14
Biotin supply affects rates of cell proliferation, biotinylation of carboxylases and histones, and expression of the gene encoding the sodium-dependent multivitamin transporter in JAr choriocarcinoma cells. Eur J Nutr (2004) 1.14
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Biotinylation of K12 in histone H4 decreases in response to DNA double-strand breaks in human JAr choriocarcinoma cells. J Nutr (2005) 1.13
Array-based comparative genomic hybridization analysis of 1176 consecutive clinical genetics investigations. Genet Med (2008) 1.13
Feeding Drosophila a biotin-deficient diet for multiple generations increases stress resistance and lifespan and alters gene expression and histone biotinylation patterns. J Nutr (2007) 1.11
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Biotin deficiency decreases life span and fertility but increases stress resistance in Drosophila melanogaster. J Nutr Biochem (2004) 1.08
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Exposure to UV light causes increased biotinylation of histones in Jurkat cells. Am J Physiol Cell Physiol (2002) 1.06
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Biotinidase catalyzes debiotinylation of histones. Eur J Nutr (2002) 1.03
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The role of histone H4 biotinylation in the structure of nucleosomes. PLoS One (2011) 1.01
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Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas. Mol Cell Biol (2013) 1.00
p66Shc protein is upregulated by steroid hormones in hormone-sensitive cancer cells and in primary prostate carcinomas. Int J Cancer (2004) 0.99
Jurkat cells respond to biotin deficiency with increased nuclear translocation of NF-kappaB, mediating cell survival. Int J Vitam Nutr Res (2004) 0.99
N- and C-terminal domains in human holocarboxylase synthetase participate in substrate recognition. Mol Genet Metab (2009) 0.99
Expression of oncogenes depends on biotin in human small cell lung cancer cells NCI-H69. Int J Vitam Nutr Res (2003) 0.98
Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA. J Mol Biol (2008) 0.97
Nipped-A, the Tra1/TRRAP subunit of the Drosophila SAGA and Tip60 complexes, has multiple roles in Notch signaling during wing development. Mol Cell Biol (2006) 0.97
Biotin requirements are lower in human Jurkat lymphoid cells but homeostatic mechanisms are similar to those of HepG2 liver cells. J Nutr (2010) 0.96
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Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma. Blood (2013) 0.96
HepG2 cells develop signs of riboflavin deficiency within 4 days of culture in riboflavin-deficient medium. J Nutr Biochem (2005) 0.95
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Synthesis of a rabbit polyclonal antibody to the human sodium-dependent multivitamin transporter. Int J Vitam Nutr Res (2002) 0.95
Cigarette smoking, familial hematopoietic cancer, hair dye use, and risk of t(14;18)-defined subtypes of non-Hodgkin's lymphoma. Am J Epidemiol (2007) 0.95
Clusters of biotin-responsive genes in human peripheral blood mononuclear cells. J Nutr Biochem (2004) 0.94
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K16-biotinylated histone H4 is overrepresented in repeat regions and participates in the repression of transcriptionally competent genes in human Jurkat lymphoid cells. J Nutr Biochem (2011) 0.94
A novel, enigmatic histone modification: biotinylation of histones by holocarboxylase synthetase. Nutr Rev (2008) 0.94
Biotin regulates the expression of holocarboxylase synthetase in the miR-539 pathway in HEK-293 cells. J Nutr (2010) 0.94
High-throughput immunoblotting identifies biotin-dependent signaling proteins in HepG2 hepatocarcinoma cells. J Nutr (2005) 0.92
An increased frequency of 13q deletions detected by fluorescence in situ hybridization and its impact on survival in children and adolescents with Burkitt lymphoma: results from the Children's Oncology Group study CCG-5961. Br J Haematol (2009) 0.92
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Epigenetic regulation of chromatin structure and gene function by biotin. J Nutr (2006) 0.92
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Holocarboxylase synthetase interacts physically with euchromatic histone-lysine N-methyltransferase, linking histone biotinylation with methylation events. J Nutr Biochem (2013) 0.91
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Effects of single-nucleotide polymorphisms in the human holocarboxylase synthetase gene on enzyme catalysis. Eur J Hum Genet (2011) 0.90
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