Published in Cytometry A on January 01, 2009
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell (2010) 5.07
Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet (2011) 4.85
Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature (2010) 3.93
The tortoise and the hair: slow-cycling cells in the stem cell race. Cell (2009) 3.90
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell (2010) 3.69
Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell Stem Cell (2014) 2.24
Inflammatory signals regulate hematopoietic stem cells. Trends Immunol (2011) 2.21
Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood (2011) 1.86
Treatment of chronic myelogenous leukemia by blocking cytokine alterations found in normal stem and progenitor cells. Cancer Cell (2015) 1.55
Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature (2015) 1.47
Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib. Drug Metab Dispos (2010) 1.41
Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice. J Clin Invest (2010) 1.41
Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood (2012) 1.41
Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation. Blood (2015) 1.39
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment. Nat Immunol (2013) 1.28
Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells. Exp Hematol (2010) 1.28
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation. Nat Cell Biol (2013) 1.16
Stem cell recruitment after injury: lessons for regenerative medicine. Regen Med (2012) 1.14
Accurate expression profiling of very small cell populations. PLoS One (2010) 1.13
Advances in complex multiparameter flow cytometry technology: Applications in stem cell research. Cytometry B Clin Cytom (2009) 1.10
Downstream targets of HOXB4 in a cell line model of primitive hematopoietic progenitor cells. Blood (2010) 1.10
Microfluidic blood cell sorting: now and beyond. Small (2014) 1.07
Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells. PLoS One (2011) 1.06
Stem cell therapy for retinal diseases: update. Stem Cell Res Ther (2011) 1.05
Single-cell technologies are revolutionizing the approach to rare cells. Immunol Cell Biol (2015) 1.01
TGF-β family signaling in stem cells. Biochim Biophys Acta (2012) 1.01
Characterization of immune-matched hematopoietic transplantation in zebrafish. Blood (2011) 0.99
Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells. Cell Stem Cell (2015) 0.96
Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress. Blood (2012) 0.93
Candida albicans induces selective development of macrophages and monocyte derived dendritic cells by a TLR2 dependent signalling. PLoS One (2011) 0.93
Characterization of the effects of exercise training on hematopoietic stem cell quantity and function. J Appl Physiol (1985) (2012) 0.87
CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation. Blood (2011) 0.87
Hematopoietic stem cell characterization and isolation. Methods Mol Biol (2011) 0.86
Multi-parameter fluorescence-activated cell sorting and analysis of stem and progenitor cells in myeloid malignancies. Best Pract Res Clin Haematol (2010) 0.86
Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer. Bone (2012) 0.86
Diabetes reduces bone marrow and circulating porcine endothelial progenitor cells, an effect ameliorated by atorvastatin and independent of cholesterol. Cytometry A (2009) 0.84
High fat diet rapidly suppresses B lymphopoiesis by disrupting the supportive capacity of the bone marrow niche. PLoS One (2014) 0.84
Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors. Exp Hematol (2012) 0.82
Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS One (2015) 0.82
KIT receptor gain-of-function in hematopoiesis enhances stem cell self-renewal and promotes progenitor cell expansion. Stem Cells (2013) 0.82
The New Zealand black mouse as a model for the development and progression of chronic lymphocytic leukemia. Cytometry B Clin Cytom (2010) 0.82
Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells. Cell Rep (2014) 0.81
Clonal-level responses of functionally distinct hematopoietic stem cells to trophic factors. Exp Hematol (2013) 0.81
Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science. Biotechnol J (2015) 0.80
Frequency of acute myeloid leukaemia-associated mouse chromosome 2 deletions in X-ray exposed immature haematopoietic progenitors and stem cells. Mutat Res (2013) 0.80
The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the lymphoblastic leukemia gene, Lyl1 can support leukemia formation. Leuk Res (2010) 0.79
TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs. Blood (2011) 0.79
A CXCR4-targeted site-specific antibody-drug conjugate. Angew Chem Int Ed Engl (2014) 0.79
Contrasting roles for C/EBPα and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects. Stem Cells (2015) 0.79
A new allele of Lyl1 confirms its important role in hematopoietic stem cell function. Genesis (2011) 0.78
Practical murine hematopathology: a comparative review and implications for research. Comp Med (2015) 0.78
ERK Signaling Is Essential for Macrophage Development. PLoS One (2015) 0.78
Macrophages: Regulators of the Inflammatory Microenvironment during Mammary Gland Development and Breast Cancer. Mediators Inflamm (2016) 0.77
Getting Down to Specifics: Profiling Gene Expression and Protein-DNA Interactions in a Cell Type-Specific Manner. Adv Genet (2015) 0.77
Alterations in the mir-15a/16-1 Loci Impairs Its Processing and Augments B-1 Expansion in De Novo Mouse Model of Chronic Lymphocytic Leukemia (CLL). PLoS One (2016) 0.77
Early hematopoiesis and macrophage development. Semin Immunol (2016) 0.77
Mitoquinone restores platelet production in irradiation-induced thrombocytopenia. Platelets (2014) 0.77
Trabecular and Cortical Bone of Growing C3H Mice Is Highly Responsive to the Removal of Weightbearing. PLoS One (2016) 0.76
CD150(-) Side Population Defines Leukemia Stem Cells in a BALB/c Mouse Model of CML and Is Depleted by Genetic Loss of SIRT1. Stem Cells (2015) 0.76
EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer. PLoS Biol (2016) 0.76
The peripheral chimerism of bone marrow-derived stem cells after transplantation: regeneration of gastrointestinal tissues in lethally irradiated mice. J Cell Mol Med (2014) 0.76
The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis. PLoS One (2016) 0.76
Challenges and Opportunities to Harnessing the (Hematopoietic) Stem Cell Niche. Curr Stem Cell Rep (2016) 0.76
Rosiglitazone Promotes Bone Marrow Adipogenesis to Impair Myelopoiesis under Stress. PLoS One (2016) 0.76
Identification of key regulatory pathways of myeloid differentiation using an mESC-based karyotypically normal cell model. Blood (2012) 0.75
Hematopoietic stem cell transplantation for multiple sclerosis: is it a clinical reality? Stem Cell Res Ther (2016) 0.75
Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery. PLoS Genet (2013) 0.75
Pituitary adenylate cyclase-activating polypeptide (PACAP) contributes to the proliferation of hematopoietic progenitor cells in murine bone marrow via PACAP-specific receptor. Sci Rep (2016) 0.75
Deciphering hepatocellular responses to metabolic and oncogenic stress. J Biol Methods (2015) 0.75
Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model. Cell Death Dis (2016) 0.75
The GNAS(R201C) mutation associated with clonal hematopoiesis supports transplantable hematopoietic stem cell activity. Exp Hematol (2017) 0.75
Extended time-lapse in vivo imaging of tibia bone marrow to visualize dynamic hematopoietic stem cell engraftment. Leukemia (2016) 0.75
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell (2005) 24.00
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med (1996) 17.51
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature (2000) 16.75
Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell (1997) 12.60
Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med (1997) 6.13
Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med (2005) 5.68
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity (2001) 5.14
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell (2004) 4.28
In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells. Blood (1992) 3.15
Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance. Cell Stem Cell (2007) 2.96
Hematopoietic stem cells do not engraft with absolute efficiencies. Blood (2005) 2.81
Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. Blood (2005) 2.48
CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood (2007) 2.27
High-resolution video monitoring of hematopoietic stem cells cultured in single-cell arrays identifies new features of self-renewal. Proc Natl Acad Sci U S A (2006) 1.56
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The combined use of Hoechst efflux ability and aldehyde dehydrogenase activity to identify murine and human hematopoietic stem cells. Exp Hematol (2007) 1.28
Cellular volume and marker expression in human peripheral blood apheresis stem cells. Cytometry A (2008) 1.06
Critical role of flow cytometry in evaluating peripheral blood hematopoietic stem cell grafts. Cytometry A (2004) 1.04
Biology of CD34+CD38- cells in lymphohematopoiesis. Leuk Lymphoma (1998) 1.02
Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol (2002) 5.74
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol (2007) 5.48
Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet (2011) 4.85
Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell (2007) 4.06
Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol (2004) 3.94
Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature (2010) 3.93
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell (2010) 3.69
Failure of bone marrow cells to transdifferentiate into neural cells in vivo. Science (2002) 3.18
Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates. Nat Med (2003) 2.91
Hematopoietic stem cells do not engraft with absolute efficiencies. Blood (2005) 2.81
The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation. Cell Stem Cell (2008) 2.57
Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc Natl Acad Sci U S A (2002) 2.39
Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat Rev Immunol (2011) 2.38
CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood (2007) 2.27
Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration. J Clin Invest (2003) 2.23
Inflammatory signals regulate hematopoietic stem cells. Trends Immunol (2011) 2.21
The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood (2006) 2.10
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways. Blood (2006) 1.98
Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood (2011) 1.86
Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood (2015) 1.75
Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell (2012) 1.71
Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival. Cell Stem Cell (2009) 1.69
Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners. J Clin Invest (2004) 1.67
Anti-CD45-mediated cytoreduction to facilitate allogeneic stem cell transplantation. Blood (2002) 1.59
MOABS: model based analysis of bisulfite sequencing data. Genome Biol (2014) 1.53
Evidence for diversity in transcriptional profiles of single hematopoietic stem cells. PLoS Genet (2006) 1.51
Isolation and characterization of functional mammary gland stem cells. Cell Prolif (2003) 1.49
Efficacy of delayed administration of post-chemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics. Exp Hematol (2007) 1.48
Primitive adult hematopoietic stem cells can function as osteoblast precursors. Proc Natl Acad Sci U S A (2003) 1.47
Roles of Sca-1 in hematopoietic stem/progenitor cell function. Exp Hematol (2005) 1.45
Skeletal muscle fiber-specific green autofluorescence: potential for stem cell engraftment artifacts. Stem Cells (2004) 1.42
Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood (2012) 1.41
The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells. Nat Cell Biol (2010) 1.40
A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells. Blood (2013) 1.38
Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood (2003) 1.38
Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. PLoS Genet (2012) 1.35
Flow cytometry analysis of murine hematopoietic stem cells. Cytometry A (2012) 1.29
Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells. Exp Hematol (2010) 1.28
Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells. J Biol Chem (2013) 1.24
Cells of the hepatic side population contribute to liver regeneration and can be replenished with bone marrow stem cells. Haematologica (2003) 1.21
Mechanisms of hematopoietic stem cell aging. Exp Gerontol (2009) 1.11
An argument against a role for Oct4 in somatic stem cells. Cell Stem Cell (2007) 1.07
Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans. PLoS One (2011) 1.06
Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells. PLoS One (2011) 1.06
The Hematopoietic Expression Viewer: expanding mobile apps as a scientific tool. Bioinformatics (2012) 1.05
The therapeutic potential of stem cells from adults. BMJ (2002) 1.03
Transient RNA interference in hematopoietic progenitors with functional consequences. Genesis (2003) 1.03
Purification of hematopoietic stem cells using the side population. Methods Enzymol (2006) 1.01
Pluripotentiality and conditional transgene regulation in human embryonic stem cells expressing insulated tetracycline-ON transactivator. Stem Cells (2007) 1.00
Plasticity and tissue regenerative potential of bone marrow-derived cells. Stem Cell Rev (2005) 0.98
Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage. Biochemistry (2004) 0.97
Realistic prospects for stem cell therapeutics. Hematology Am Soc Hematol Educ Program (2003) 0.96
The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors. Nat Immunol (2012) 0.93
Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells. PLoS One (2008) 0.93
CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway. PLoS Biol (2011) 0.91
Circulating hematopoietic stem cells do not efficiently home to bone marrow during homeostasis. Exp Hematol (2004) 0.91
Identification and characterization of side population cells in embryonic stem cell cultures. Stem Cells Dev (2009) 0.90
Stem cells: a minireview. J Cell Biochem Suppl (2002) 0.90
Chk1 haploinsufficiency results in anemia and defective erythropoiesis. PLoS One (2010) 0.89
Bringing cardiovascular cell-based therapy to clinical application: perspectives based on a National Heart, Lung, and Blood Institute Cell Therapy Working Group meeting. Am Heart J (2007) 0.89
An in vivo propagated human acute myeloid leukemia expressing ABCA3. Leuk Res (2004) 0.88
Molecular profiling of hematopoietic stem cells. Methods Mol Med (2007) 0.88
Altered phenotype and reduced function of muscle-derived hematopoietic stem cells. Exp Hematol (2003) 0.88
CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation. Blood (2011) 0.87
Complement-fixing CD45 monoclonal antibodies to facilitate stem cell transplantation in mouse and man. Ann N Y Acad Sci (2003) 0.87
Hematopoietic stem cell characterization and isolation. Methods Mol Biol (2011) 0.86
Investigating the role of hematopoietic stem and progenitor cells in regulating the osteogenic differentiation of mesenchymal stem cells in vitro. J Orthop Res (2011) 0.85
Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors. Exp Hematol (2012) 0.82
Differential mRNA processing in hematopoietic stem cells. Stem Cells (2005) 0.81
LYL1 degradation by the proteasome is directed by a N-terminal PEST rich site in a phosphorylation-independent manner. PLoS One (2010) 0.81
Tracing the origin of non-hematopoietic cells using CD45 PCR restriction fragment length polymorphisms. Biotechniques (2003) 0.80
Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression. Mol Cancer (2009) 0.80
Techniques for the study of adult stem cells: be fruitful and multiply. Biotechniques (2003) 0.80
Isolation and characterization of mouse side population cells. Methods Mol Biol (2013) 0.79
TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs. Blood (2011) 0.79
The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the lymphoblastic leukemia gene, Lyl1 can support leukemia formation. Leuk Res (2010) 0.79
DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell (2016) 0.78
Adenoviral transduction of mouse hematopoietic stem cells. Mol Ther (2003) 0.78
A new allele of Lyl1 confirms its important role in hematopoietic stem cell function. Genesis (2011) 0.78
Use of CD9 expression to enrich for porcine hematopoietic progenitors. Exp Hematol (2002) 0.77
Enhanced generation of myeloid lineages in hematopoietic differentiation from embryonic stem cells by silencing transcriptional repressor Twist-2. Cloning Stem Cells (2009) 0.77
Bridge over troubled stem cells. Mol Ther (2011) 0.75
Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery. PLoS Genet (2013) 0.75
Direct conversion of skin cells into blood: alchemy or science? Mol Ther (2011) 0.75
Confounding by repetitive elements and CpG islands does not explain the association between hypomethylation and genomic instability. PLoS Genet (2013) 0.75
Stem Cells and Aging: What's Next? Cell Stem Cell (2015) 0.75
Dynamic DNA methylation discovered during HSC differentiation. Cell Cycle (2015) 0.75
Rising from the crypt: decreasing DNA methylation during differentiation of the small intestine. Genome Biol (2013) 0.75
Editorial retraction. Stem Cells (2006) 0.75
Advancing the fast-paced field of stem cell research: stem cells increases from 6 to 10 issues in its 23rd year of publication. Stem Cells (2005) 0.75