Published in PLoS One on January 21, 2011
Interferon-inducible effector mechanisms in cell-autonomous immunity. Nat Rev Immunol (2012) 2.21
Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood (2011) 1.86
IFN-inducible GTPases in host cell defense. Cell Host Microbe (2012) 1.53
Autophagy as an immune effector against tuberculosis. Curr Opin Microbiol (2013) 1.19
Autophagy in immunity: implications in etiology of autoimmune/autoinflammatory diseases. Autophagy (2012) 1.16
Autophagy: a core cellular process with emerging links to pulmonary disease. Am J Respir Crit Care Med (2011) 1.00
Polymorphisms in autophagy genes and susceptibility to tuberculosis. PLoS One (2012) 1.00
IRGM variants and susceptibility to inflammatory bowel disease in the German population. PLoS One (2013) 0.98
Autophagy in the fight against tuberculosis. DNA Cell Biol (2015) 0.97
Autophagy in inflammatory diseases. Int J Cell Biol (2011) 0.94
Autophagy deficiency by hepatic FIP200 deletion uncouples steatosis from liver injury in NAFLD. Mol Endocrinol (2013) 0.91
Association of IRGM polymorphisms and susceptibility to pulmonary tuberculosis in Zahedan, Southeast Iran. ScientificWorldJournal (2012) 0.90
IRGM in autophagy and viral infections. Front Immunol (2013) 0.90
CD14 -159 C>T gene polymorphism with increased risk of tuberculosis: evidence from a meta-analysis. PLoS One (2013) 0.85
Cell death and autophagy in tuberculosis. Semin Immunol (2014) 0.85
The innate immune response in human tuberculosis. Cell Microbiol (2015) 0.85
IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis. Autophagy (2014) 0.83
Cell-autonomous effector mechanisms against mycobacterium tuberculosis. Cold Spring Harb Perspect Med (2014) 0.82
Autophagy in tuberculosis. Cold Spring Harb Perspect Med (2014) 0.81
Host cell autophagy in immune response to zoonotic infections. Clin Dev Immunol (2011) 0.77
Human ULK1 Variation and Susceptibility to Mycobacterium tuberculosis Infection. J Infect Dis (2016) 0.75
Association of LMP/TAP gene polymorphisms with tuberculosis susceptibility in Li population in China. PLoS One (2012) 0.75
Autophagy Is an Innate Mechanism Associated with Leprosy Polarization. PLoS Pathog (2017) 0.75
The dual mechanism of action of 5-Nitro-1,10-Phenanthroline against Mycobacterium tuberculosis. Antimicrob Agents Chemother (2017) 0.75
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet (2007) 13.74
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet (2008) 9.52
Immune control of tuberculosis by IFN-gamma-inducible LRG-47. Science (2003) 5.50
p47 GTPases: regulators of immunity to intracellular pathogens. Nat Rev Immunol (2004) 2.52
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains. PLoS Pathog (2009) 2.35
IFN-inducible GTPases and immunity to intracellular pathogens. Trends Immunol (2004) 2.11
Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease. PLoS One (2007) 1.89
IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens. Cell Microbiol (2007) 1.75
The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death. Nat Immunol (2008) 1.73
Death and resurrection of the human IRGM gene. PLoS Genet (2009) 1.72
5' dinucleotide repeat polymorphism of NRAMP1 and susceptibility to tuberculosis among Caucasian patients in Houston, Texas. Int J Tuberc Lung Dis (2002) 1.71
Association between interleukin-8 gene alleles and human susceptibility to tuberculosis disease. J Infect Dis (2003) 1.68
Common nonsynonymous polymorphisms in the NOD2 gene are associated with resistance or susceptibility to tuberculosis disease in African Americans. J Infect Dis (2008) 1.23
Synergistic pandemics: confronting the global HIV and tuberculosis epidemics. Clin Infect Dis (2010) 1.06
Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis. Clin Chim Acta (2010) 1.06
Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol (2002) 5.74
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol (2007) 5.48
Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy. AIDS (2005) 5.08
Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet (2011) 4.85
spa typing method for discriminating among Staphylococcus aureus isolates: implications for use of a single marker to detect genetic micro- and macrovariation. J Clin Microbiol (2004) 4.80
Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell (2007) 4.06
Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol (2004) 3.94
Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature (2010) 3.93
Comparative and demographic analysis of orang-utan genomes. Nature (2011) 3.83
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell (2010) 3.69
Genome-wide analysis of group a streptococci reveals a mutation that modulates global phenotype and disease specificity. PLoS Pathog (2006) 3.68
Single-nucleotide polymorphism-based population genetic analysis of Mycobacterium tuberculosis strains from 4 geographic sites. J Infect Dis (2005) 3.32
Failure of bone marrow cells to transdifferentiate into neural cells in vivo. Science (2002) 3.18
Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates. Nat Med (2003) 2.91
Hematopoietic stem cells do not engraft with absolute efficiencies. Blood (2005) 2.81
Single nucleotide polymorphisms in genes associated with isoniazid resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother (2003) 2.71
The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation. Cell Stem Cell (2008) 2.57
Spectrum of bacille Calmette-Guérin (BCG) infection after intravesical BCG immunotherapy. Clin Infect Dis (2003) 2.50
Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc Natl Acad Sci U S A (2002) 2.39
Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat Rev Immunol (2011) 2.38
Clinical and molecular analysis of macrolide resistance in Mycobacterium avium complex lung disease. Am J Respir Crit Care Med (2006) 2.34
Factors associated with the use of highly active antiretroviral therapy in patients newly entering care in an urban clinic. J Acquir Immune Defic Syndr (2003) 2.33
Mouse hematopoietic stem cell identification and analysis. Cytometry A (2009) 2.32
Interferon-γ release assays and tuberculin skin testing for diagnosis of latent tuberculosis infection in healthcare workers in the United States. Am J Respir Crit Care Med (2014) 2.29
CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood (2007) 2.27
Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration. J Clin Invest (2003) 2.23
Inflammatory signals regulate hematopoietic stem cells. Trends Immunol (2011) 2.21
Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. Cell (2013) 2.16
Test variability of the QuantiFERON-TB gold in-tube assay in clinical practice. Am J Respir Crit Care Med (2012) 2.14
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet (2011) 2.13
The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood (2006) 2.10
Treatment practices, outcomes, and costs of multidrug-resistant and extensively drug-resistant tuberculosis, United States, 2005-2007. Emerg Infect Dis (2014) 2.03
A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. Proc Natl Acad Sci U S A (2008) 2.02
Streptococcus pyogenes pili promote pharyngeal cell adhesion and biofilm formation. Mol Microbiol (2007) 2.01
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways. Blood (2006) 1.98
Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease. PLoS One (2007) 1.89
Portable, battery-operated, low-cost, bright field and fluorescence microscope. PLoS One (2010) 1.88
Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood (2011) 1.86
Genetic polymorphism in Mycobacterium tuberculosis isolates from patients with chronic multidrug-resistant tuberculosis. J Infect Dis (2004) 1.75
Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood (2015) 1.75
Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell (2012) 1.71
Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival. Cell Stem Cell (2009) 1.69
rpoB Gene mutations and molecular characterization of rifampin-resistant Mycobacterium tuberculosis isolates from Shandong Province, China. J Clin Microbiol (2006) 1.68
Association between interleukin-8 gene alleles and human susceptibility to tuberculosis disease. J Infect Dis (2003) 1.68
Molecular epidemiology of VHL gene mutations in renal cell carcinoma patients: relation to dietary and other factors. Carcinogenesis (2002) 1.68
Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners. J Clin Invest (2004) 1.67
LncRNAs expression signatures of renal clear cell carcinoma revealed by microarray. PLoS One (2012) 1.59
Anti-CD45-mediated cytoreduction to facilitate allogeneic stem cell transplantation. Blood (2002) 1.59
A chemokine-degrading extracellular protease made by group A Streptococcus alters pathogenesis by enhancing evasion of the innate immune response. Infect Immun (2008) 1.54
MOABS: model based analysis of bisulfite sequencing data. Genome Biol (2014) 1.53
Group A Streptococcus gene expression in humans and cynomolgus macaques with acute pharyngitis. Infect Immun (2003) 1.53
Effect of pneumococcal vaccination: a comparison of vaccination rates in patients with bacteremic and nonbacteremic pneumococcal pneumonia. Clin Infect Dis (2006) 1.52
Relationships of sleep duration with sleep disturbances, basic socio-demographic factors, and BMI in Chinese people. Sleep Med (2009) 1.51
Evidence for diversity in transcriptional profiles of single hematopoietic stem cells. PLoS Genet (2006) 1.51
Transmission of multidrug-resistant tuberculosis in the USA: a cross-sectional study. Lancet Infect Dis (2013) 1.50
Detection of Clostridium difficile toxin: comparison of enzyme immunoassay results with results obtained by cytotoxicity assay. J Clin Microbiol (2007) 1.49
Epidemiology of tuberculosis in young children in the United States. Pediatrics (2014) 1.49
Isolation and characterization of functional mammary gland stem cells. Cell Prolif (2003) 1.49
Applying narrow-band imaging in complement with white-light imaging cystoscopy in the detection of urothelial carcinoma of the bladder. Urol Oncol (2011) 1.48
Efficacy of delayed administration of post-chemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics. Exp Hematol (2007) 1.48
Primitive adult hematopoietic stem cells can function as osteoblast precursors. Proc Natl Acad Sci U S A (2003) 1.47
Roles of Sca-1 in hematopoietic stem/progenitor cell function. Exp Hematol (2005) 1.45
Molecular characteristics of nosocomial and Native American community-associated methicillin-resistant Staphylococcus aureus clones from rural Wisconsin. J Clin Microbiol (2004) 1.45
Evaluation of QuantiFERON-TB gold in-tube and tuberculin skin tests among immigrant children being screened for latent tuberculosis infection. Pediatr Infect Dis J (2015) 1.45
Retrospective comparison of retroperitoneal laparoscopic versus open dismembered pyeloplasty for ureteropelvic junction obstruction. J Urol (2006) 1.44
Skeletal muscle fiber-specific green autofluorescence: potential for stem cell engraftment artifacts. Stem Cells (2004) 1.42
Contemporary neurosurgical approaches to neurocysticercosis. Am J Trop Med Hyg (2009) 1.41
Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood (2012) 1.41
Electroconvulsive therapy in China: clinical practice and research on efficacy. J ECT (2012) 1.40
Evolving renorrhaphy technique for retroperitoneal laparoscopic partial nephrectomy: single-surgeon series. Int J Urol (2014) 1.40
The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells. Nat Cell Biol (2010) 1.40
Laparoscopic adrenalectomy for beginners without open counterpart experience: initial results under staged training. Urology (2009) 1.40
A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells. Blood (2013) 1.38
Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood (2003) 1.38
Renal pedicle lymphatic disconnection for chyluria via retroperitoneoscopy and open surgery: report of 53 cases with followup. J Urol (2005) 1.38
Pulsed-field gel electrophoresis study of Mycobacterium abscessus isolates previously affected by DNA degradation. J Clin Microbiol (2004) 1.37
Genotypic analysis of multidrug-resistant Mycobacterium tuberculosis isolates from Monterrey, Mexico. J Med Microbiol (2004) 1.37
Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. PLoS Genet (2012) 1.35
Tuberculosis disparity between US-born blacks and whites, Houston, Texas, USA. Emerg Infect Dis (2009) 1.33
Epidemiology of neurocysticercosis in Houston, Texas. Am J Trop Med Hyg (2005) 1.30
Alleles of the NRAMP1 gene are risk factors for pediatric tuberculosis disease. Proc Natl Acad Sci U S A (2005) 1.30
Flow cytometry analysis of murine hematopoietic stem cells. Cytometry A (2012) 1.29
Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells. Exp Hematol (2010) 1.28
Genetic diversity among type emm28 group A Streptococcus strains causing invasive infections and pharyngitis. J Clin Microbiol (2005) 1.26
Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells. J Biol Chem (2013) 1.24
TRPC1 associates with BK(Ca) channel to form a signal complex in vascular smooth muscle cells. Circ Res (2009) 1.24
Internal fixation of distal tibiofibular syndesmotic injuries: a systematic review with meta-analysis. Int Orthop (2013) 1.23
Common nonsynonymous polymorphisms in the NOD2 gene are associated with resistance or susceptibility to tuberculosis disease in African Americans. J Infect Dis (2008) 1.23
Detection of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis using denaturing gradient gel electrophoresis. Antimicrob Agents Chemother (2005) 1.22
Cells of the hepatic side population contribute to liver regeneration and can be replenished with bone marrow stem cells. Haematologica (2003) 1.21
Mycobacterium simae outbreak associated with a hospital water supply. Infect Control Hosp Epidemiol (2004) 1.21
The baker's yeast diploid genome is remarkably stable in vegetative growth and meiosis. PLoS Genet (2010) 1.20
Laparoscopic colon resection early in the learning curve: what is the appropriate setting? Ann Surg (2006) 1.19
Neurocysticercosis in Houston, Texas: an update. Medicine (Baltimore) (2011) 1.19
Scale-adaptive surface modeling of vascular structures. Biomed Eng Online (2010) 1.18
Comparing the tuberculin skin test and T-SPOT.TB blood test in children. Pediatrics (2010) 1.17