PubRank

Bernard Thorens

Author PubWeight™ 93.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 2009 9.24
2 Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver. Diabetes 2005 2.88
3 Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice. Cell Metab 2008 2.60
4 The SLC2 family of facilitated hexose and polyol transporters. Pflugers Arch 2003 2.58
5 Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet. Am J Physiol Endocrinol Metab 2002 2.33
6 Uric acid transport and disease. J Clin Invest 2010 2.33
7 International Union of Pharmacology. XXXV. The glucagon receptor family. Pharmacol Rev 2003 2.25
8 Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors. J Clin Invest 2004 2.11
9 The SLC2 (GLUT) family of membrane transporters. Mol Aspects Med 2013 1.97
10 Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice. J Lipid Res 2008 1.91
11 Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. Am J Physiol Endocrinol Metab 2002 1.82
12 Brain glucose sensing, counterregulation, and energy homeostasis. Physiology (Bethesda) 2007 1.74
13 Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors. J Clin Invest 2005 1.56
14 GLUT2 is a high affinity glucosamine transporter. FEBS Lett 2002 1.47
15 PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells. Genes Dev 2008 1.38
16 Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension. Diabetes 2004 1.38
17 Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice. Swiss Med Wkly 2003 1.38
18 Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway. Diabetes 2008 1.27
19 Hepatic glucose sensing is required to preserve β cell glucose competence. J Clin Invest 2013 1.27
20 Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding. Diabetes 2006 1.27
21 Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice. Diabetes 2011 1.26
22 GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion. Mol Cell Endocrinol 2007 1.24
23 Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy. Proc Natl Acad Sci U S A 2009 1.23
24 Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop. Diabetes 2009 1.20
25 Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14. Diabetes 2007 1.20
26 MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity. J Clin Invest 2012 1.17
27 Mouse GLUT9: evidences for a urate uniporter. Am J Physiol Renal Physiol 2009 1.15
28 Regulation of adaptive behaviour during fasting by hypothalamic Foxa2. Nature 2009 1.10
29 Transcript profiling suggests that differential metabolic adaptation of mice to a high fat diet is associated with changes in liver to muscle lipid fluxes. J Biol Chem 2004 1.08
30 Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain. Endocrinology 2006 1.08
31 Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression. J Biol Chem 2010 1.06
32 Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons. FASEB J 2010 1.05
33 Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight. Cell Metab 2011 1.05
34 Gonadotropin-releasing hormone secretion from hypothalamic neurons: stimulation by insulin and potentiation by leptin. Endocrinology 2003 1.04
35 Immunolocalization of GLUTX1 in the testis and to specific brain areas and vasopressin-containing neurons. Endocrinology 2002 1.03
36 Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced pro-inflammatory state. J Biol Chem 2010 1.03
37 GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function. Mol Cell Biol 2006 1.02
38 GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization. J Clin Invest 2003 1.01
39 PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance. Proc Natl Acad Sci U S A 2011 0.98
40 Regulated exocytosis of an H+/myo-inositol symporter at synapses and growth cones. EMBO J 2004 0.98
41 In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice. Diabetes 2011 0.98
42 Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain--an immunohistochemical study. J Chem Neuroanat 2004 0.98
43 Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway. Am J Physiol Endocrinol Metab 2002 0.96
44 The role of sodium-coupled glucose co-transporter 3 in the satiety effect of portal glucose sensing. Mol Metab 2012 0.96
45 Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of beta-cells. Diabetes 2006 0.95
46 Nervous glucose sensing regulates postnatal β cell proliferation and glucose homeostasis. J Clin Invest 2013 0.93
47 The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells. J Cell Sci 2003 0.92
48 Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice. Bone 2012 0.92
49 Deficiency of glucose-dependent insulinotropic polypeptide receptor prevents ovariectomy-induced obesity in mice. Am J Physiol Endocrinol Metab 2008 0.91
50 Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype. J Biol Chem 2003 0.91
51 Immunocytochemical localization of the glucose transporter 2 (GLUT2) in the adult rat brain. II. Electron microscopic study. J Chem Neuroanat 2004 0.88
52 Glucose-dependent insulinotropic polypeptide receptor knockout mice are impaired in learning, synaptic plasticity, and neurogenesis. J Neurophysiol 2011 0.88
53 Different transcriptional control of metabolism and extracellular matrix in visceral and subcutaneous fat of obese and rimonabant treated mice. PLoS One 2008 0.87
54 Neurochemical profile of the mouse hypothalamus using in vivo 1H MRS at 14.1T. NMR Biomed 2010 0.86
55 GLUT8 subcellular localization and absence of translocation to the plasma membrane in PC12 cells and hippocampal neurons. Endocrinology 2005 0.86
56 Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in β-cells. Proc Natl Acad Sci U S A 2013 0.85
57 Oxidative phosphorylation flexibility in the liver of mice resistant to high-fat diet-induced hepatic steatosis. Diabetes 2011 0.84
58 EuroDia: a beta-cell gene expression resource. Database (Oxford) 2010 0.84
59 GLP-1 protects β-cells against apoptosis by enhancing the activity of an IGF-2/IGF1-receptor autocrine loop. Islets 2010 0.84
60 Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development. Basic Res Cardiol 2013 0.84
61 cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells. Diabetes 2002 0.83
62 Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth. J Neurosci Res 2009 0.83
63 PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice. J Clin Invest 2012 0.82
64 Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion. J Biol Chem 2005 0.82
65 The peroxisomal enzyme L-PBE is required to prevent the dietary toxicity of medium-chain fatty acids. Cell Rep 2013 0.81
66 Type 2 Diabetes, SGLT2 Inhibitors, and Glucose Secretion. N Engl J Med 2015 0.81
67 Urate-induced acute renal failure and chronic inflammation in liver-specific Glut9 knockout mice. Am J Physiol Renal Physiol 2013 0.81
68 Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease. PLoS One 2011 0.80
69 Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta-cells. Mol Endocrinol 2009 0.79
70 Expression of the NH(2)-terminal fragment of RasGAP in pancreatic beta-cells increases their resistance to stresses and protects mice from diabetes. Diabetes 2009 0.78
71 Allogeneic beta-islet cells correct diabetes and resist immune rejection. Proc Natl Acad Sci U S A 2002 0.78
72 The hyperstimulated β-cell: prelude to diabetes? Diabetes Obes Metab 2012 0.77
73 Plac8 is required for white adipocyte differentiation in vitro and cell number control in vivo. PLoS One 2012 0.76
74 Tetracycline-regulated expression of VEGF-A in beta cells induces angiogenesis: improvement of engraftment following transplantation. Cell Transplant 2006 0.76
75 Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells. Endocrinology 2003 0.75