Published in Endocrinology on May 01, 2003
Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol (2009) 9.24
Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat Rev Cancer (2004) 6.73
Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med (2013) 5.62
EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev (2009) 5.61
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature (2008) 5.15
Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell (2006) 3.28
Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver. Diabetes (2005) 2.88
Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice. Cell Metab (2008) 2.60
The SLC2 family of facilitated hexose and polyol transporters. Pflugers Arch (2003) 2.58
Mechanisms of motility in metastasizing cells. Mol Cancer Res (2010) 2.42
Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin Exp Metastasis (2007) 2.41
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail. EMBO J (2006) 2.38
Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet. Am J Physiol Endocrinol Metab (2002) 2.33
Uric acid transport and disease. J Clin Invest (2010) 2.33
Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease. Cell (2010) 2.26
International Union of Pharmacology. XXXV. The glucagon receptor family. Pharmacol Rev (2003) 2.25
Immunomodulation by mesenchymal stem cells: a potential therapeutic strategy for type 1 diabetes. Diabetes (2008) 2.25
EMT as the ultimate survival mechanism of cancer cells. Semin Cancer Biol (2012) 2.22
[Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting. J Nucl Med (2006) 2.15
Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors. J Clin Invest (2004) 2.11
The SLC2 (GLUT) family of membrane transporters. Mol Aspects Med (2013) 1.97
Sprouty proteins, masterminds of receptor tyrosine kinase signaling. Angiogenesis (2008) 1.95
Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice. J Lipid Res (2008) 1.91
Molecular networks that regulate cancer metastasis. Semin Cancer Biol (2012) 1.88
Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming. Cancer Cell (2013) 1.85
Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. Am J Physiol Endocrinol Metab (2002) 1.82
Brain glucose sensing, counterregulation, and energy homeostasis. Physiology (Bethesda) (2007) 1.74
The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death. J Biol Chem (2011) 1.72
Angiopoietins in angiogenesis. Cancer Lett (2012) 1.69
Exendin-4-based radiopharmaceuticals for glucagonlike peptide-1 receptor PET/CT and SPECT/CT. J Nucl Med (2010) 1.67
NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin. EMBO J (2008) 1.62
Mouse models of breast cancer metastasis. Breast Cancer Res (2006) 1.62
The angiogenic switch in carcinogenesis. Semin Cancer Biol (2009) 1.59
Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors. J Clin Invest (2005) 1.56
Distinct mechanisms of tumor invasion and metastasis. Trends Mol Med (2007) 1.48
GLUT2 is a high affinity glucosamine transporter. FEBS Lett (2002) 1.47
Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons. Proc Natl Acad Sci U S A (2009) 1.45
Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer. J Clin Invest (2013) 1.41
PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells. Genes Dev (2008) 1.38
Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension. Diabetes (2004) 1.38
Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice. Swiss Med Wkly (2003) 1.38
Cadherins and the tumour progression: is it all in a switch? Cancer Lett (2002) 1.37
[Lys40(Ahx-DTPA-111In)NH2]-Exendin-4 is a highly efficient radiotherapeutic for glucagon-like peptide-1 receptor-targeted therapy for insulinoma. Clin Cancer Res (2007) 1.35
Generation and characterization of telomerase-transfected human lymphatic endothelial cells with an extended life span. Am J Pathol (2004) 1.35
Kidney function after islet transplant alone in type 1 diabetes: impact of immunosuppressive therapy on progression of diabetic nephropathy. Diabetes Care (2007) 1.34
The multiple languages of endothelial cell-to-cell communication. Arterioscler Thromb Vasc Biol (2006) 1.33
Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8). PLoS One (2013) 1.33
Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function. EMBO J (2007) 1.32
Corrupt policemen: inflammatory cells promote tumor angiogenesis. Curr Opin Oncol (2009) 1.29
Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway. Diabetes (2008) 1.27
Hepatic glucose sensing is required to preserve β cell glucose competence. J Clin Invest (2013) 1.27
Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding. Diabetes (2006) 1.27
Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice. Diabetes (2011) 1.26
GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion. Mol Cell Endocrinol (2007) 1.24
Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model. J Cell Mol Med (2009) 1.24
Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes. Diabetes (2010) 1.24
Multitasking in tumor progression: signaling functions of cell adhesion molecules. Ann N Y Acad Sci (2004) 1.24
Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy. Proc Natl Acad Sci U S A (2009) 1.23
The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking. J Cell Biol (2009) 1.23
Neural cell adhesion molecule regulates the cellular response to fibroblast growth factor. J Cell Sci (2007) 1.23
Myeloid cells contribute to tumor lymphangiogenesis. PLoS One (2009) 1.22
A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis. Blood (2009) 1.22
Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop. Diabetes (2009) 1.20
Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization. J Clin Invest (2014) 1.20
Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14. Diabetes (2007) 1.20
A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice. Diabetes (2010) 1.18
MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity. J Clin Invest (2012) 1.17
Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis. Am J Pathol (2007) 1.16
The adhesion molecule NCAM promotes ovarian cancer progression via FGFR signalling. EMBO Mol Med (2011) 1.16
Mouse GLUT9: evidences for a urate uniporter. Am J Physiol Renal Physiol (2009) 1.15
The differential role of L1 in ovarian carcinoma and normal ovarian surface epithelium. Cancer Res (2008) 1.14
Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation. PLoS One (2010) 1.14
Mechanisms of PDL1-mediated regulation of autoimmune diabetes. Clin Immunol (2007) 1.11
Concepts of metastasis in flux: the stromal progression model. Semin Cancer Biol (2012) 1.10
Regulation of adaptive behaviour during fasting by hypothalamic Foxa2. Nature (2009) 1.10
Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis. PLoS One (2010) 1.09
The sialomucin CD34 is a marker of lymphatic endothelial cells in human tumors. Am J Pathol (2006) 1.09
Rebuilding cancer metastasis in the mouse. Mol Oncol (2013) 1.08
The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells. J Exp Med (2009) 1.08
Transcript profiling suggests that differential metabolic adaptation of mice to a high fat diet is associated with changes in liver to muscle lipid fluxes. J Biol Chem (2004) 1.08
Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain. Endocrinology (2006) 1.08
Circulating leptin correlates with left ventricular mass in morbid (grade III) obesity before and after weight loss induced by bariatric surgery: a potential role for leptin in mediating human left ventricular hypertrophy. J Clin Endocrinol Metab (2005) 1.07
Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression. J Biol Chem (2010) 1.06
Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons. FASEB J (2010) 1.05
Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight. Cell Metab (2011) 1.05
Molecular mechanisms of lymphangiogenesis in development and cancer. Int J Dev Biol (2011) 1.05
Loss of neural cell adhesion molecule induces tumor metastasis by up-regulating lymphangiogenesis. Cancer Res (2004) 1.04
Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice. Clin Immunol (2007) 1.04
Gonadotropin-releasing hormone secretion from hypothalamic neurons: stimulation by insulin and potentiation by leptin. Endocrinology (2003) 1.04
Split personalities: the agonistic antagonist Sprouty. Nat Cell Biol (2003) 1.03
A pro-inflammatory signature mediates FGF2-induced angiogenesis. J Cell Mol Med (2009) 1.03
Immunolocalization of GLUTX1 in the testis and to specific brain areas and vasopressin-containing neurons. Endocrinology (2002) 1.03
Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced pro-inflammatory state. J Biol Chem (2010) 1.03
Can existing drugs approved for other indications retard renal function decline in patients with type 1 diabetes and nephropathy? Semin Nephrol (2012) 1.02
GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function. Mol Cell Biol (2006) 1.02
Immunological and regenerative properties of cord blood stem cells. Clin Immunol (2010) 1.01