Published in Mol Cell Endocrinol on November 21, 2008
FGF23 induces left ventricular hypertrophy. J Clin Invest (2011) 7.22
Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis. Endocrinology (2009) 2.89
Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective. Kidney Int (2010) 2.50
Fibroblast growth factor 21: from pharmacology to physiology. Am J Clin Nutr (2009) 2.35
The Fibroblast Growth Factor signaling pathway. Wiley Interdiscip Rev Dev Biol (2015) 1.82
Familial tumoral calcinosis: from characterization of a rare phenotype to the pathogenesis of ectopic calcification. J Invest Dermatol (2009) 1.51
Fundamentals of FGF19 & FGF21 action in vitro and in vivo. PLoS One (2012) 1.44
Klotho. Pflugers Arch (2010) 1.34
Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB. PLoS One (2012) 1.30
FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation. J Biol Chem (2009) 1.26
Overview of the FGF23-Klotho axis. Pediatr Nephrol (2009) 1.15
A potential link between phosphate and aging--lessons from Klotho-deficient mice. Mech Ageing Dev (2010) 1.10
Recent advances in renal phosphate handling. Nat Rev Nephrol (2010) 1.04
Endocrine fibroblast growth factor FGF19 promotes prostate cancer progression. Cancer Res (2013) 1.02
Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy. PLoS One (2011) 1.00
Decline in muscle strength and running endurance in klotho deficient C57BL/6 mice. Biogerontology (2013) 0.95
The role of Klotho in energy metabolism. Nat Rev Endocrinol (2012) 0.95
Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress. BMC Gastroenterol (2013) 0.93
Regulators of human white adipose browning: evidence for sympathetic control and sexual dimorphic responses to sprint interval training. PLoS One (2014) 0.93
In vivo pancreatic β-cell-specific expression of antiaging gene Klotho: a novel approach for preserving β-cells in type 2 diabetes. Diabetes (2014) 0.92
Association between Serum Atypical Fibroblast Growth Factors 21 and 19 and Pediatric Nonalcoholic Fatty Liver Disease. PLoS One (2013) 0.92
Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice. J Neurosci (2015) 0.91
Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury. Clin Sci (Lond) (2015) 0.89
Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress. Nutr Metab (Lond) (2012) 0.89
Lack of association of Klotho gene variants with valvular and vascular calcification in Caucasians: a candidate gene study of the Framingham Offspring Cohort. Nephrol Dial Transplant (2011) 0.88
βKlotho suppresses tumor growth in hepatocellular carcinoma by regulating Akt/GSK-3β/cyclin D1 signaling pathway. PLoS One (2013) 0.87
Diminished mTOR signaling: a common mode of action for endocrine longevity factors. Springerplus (2014) 0.84
Skeletal muscle as a regulator of the longevity protein, Klotho. Front Physiol (2014) 0.83
Fibroblast growth factor 19 entry into brain. Fluids Barriers CNS (2013) 0.82
Metformin inhibits 17β-estradiol-induced epithelial-to-mesenchymal transition via βKlotho-related ERK1/2 signaling and AMPKα signaling in endometrial adenocarcinoma cells. Oncotarget (2016) 0.81
Is fibroblast growth factor receptor 4 a suitable target of cancer therapy? Curr Pharm Des (2014) 0.80
From bone abnormalities to mineral metabolism dysregulation in autosomal dominant polycystic kidney disease. Pediatr Nephrol (2013) 0.80
Low body mass index and dyslipidemia in dialysis patients linked to elevated plasma fibroblast growth factor 23. Am J Nephrol (2013) 0.80
Periodontitis aggravated pancreatic β-cell dysfunction in diabetic mice through interleukin-12 regulation on Klotho. J Diabetes Investig (2015) 0.77
Circulating Fibroblast Growth Factor 21 (Fgf21) as Diagnostic and Prognostic Biomarker in Renal Cancer. J Mol Biomark Diagn (2016) 0.77
Influence of anaerobic and aerobic exercise on age-related pathways in skeletal muscle. Ageing Res Rev (2017) 0.75
Klotho sensitive regulation of dendritic cell functions by vitamin E. Biol Res (2016) 0.75
Vitamin D prohormone in the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. Int J Nephrol Renovasc Dis (2017) 0.75
FGF23 induces left ventricular hypertrophy. J Clin Invest (2011) 7.22
Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. Proc Natl Acad Sci U S A (2008) 2.62
FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases. Proc Natl Acad Sci U S A (2007) 2.08
Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging. Blood (2006) 1.71
Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice. J Clin Invest (2013) 1.66
FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis. J Cell Biol (2008) 1.53
Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart. Nat Commun (2012) 1.25
Klotho coreceptors inhibit signaling by paracrine fibroblast growth factor 8 subfamily ligands. Mol Cell Biol (2012) 0.96
Nuclear localization of Klotho in brain: an anti-aging protein. Neurobiol Aging (2012) 0.96
The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice. Eur J Pharmacol (2012) 0.96
Improved protein arrays for quantitative systems analysis of the dynamics of signaling pathway interactions. Proteome Sci (2011) 0.94
Hyperaldosteronism in Klotho-deficient mice. Am J Physiol Renal Physiol (2010) 0.94
Endocrine fibroblast growth factors as regulators of metabolic homeostasis. Biofactors (2009) 0.87
Protective roles of DMP1 in high phosphate homeostasis. PLoS One (2012) 0.86
Accelerated suicidal erythrocyte death in Klotho-deficient mice. Pflugers Arch (2009) 0.83
Alteration in N-glycomics during mouse aging: a role for FUT8. Aging Cell (2011) 0.83
Post-translational loss of renal TRPV5 calcium channel expression, Ca(2+) wasting, and bone loss in experimental colitis. Gastroenterology (2013) 0.82
Saturated phosphatidic acids mediate saturated fatty acid-induced vascular calcification and lipotoxicity. J Clin Invest (2015) 0.77
Amadori products promote cellular senescence activating insulin-like growth factor-1 receptor and down-regulating the antioxidant enzyme catalase. Int J Biochem Cell Biol (2013) 0.76