Published in Org Lett on January 01, 2009
Biosynthesis of galactofuranose in kinetoplastids: novel therapeutic targets for treating leishmaniasis and chagas' disease. Enzyme Res (2011) 0.94
Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents. ACS Chem Biol (2015) 0.87
Substrate-dependent dynamics of UDP-galactopyranose mutase: Implications for drug design. Protein Sci (2013) 0.84
Fluorescence Polarization Binding Assay for Aspergillus fumigatus Virulence Factor UDP-Galactopyranose Mutase. Enzyme Res (2011) 0.81
Comparing Galactan Biosynthesis in Mycobacterium tuberculosis and Corynebacterium diphtheriae. J Biol Chem (2016) 0.75
Cell wall core galactofuran synthesis is essential for growth of mycobacteria. J Bacteriol (2001) 1.90
The cell-wall core of Mycobacterium tuberculosis in the context of drug discovery. Curr Top Med Chem (2007) 1.64
Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents. J Med Chem (2004) 1.55
Galactofuranose metabolism: a potential target for antimicrobial chemotherapy. Cell Mol Life Sci (2003) 1.45
Chemical probes of UDP-galactopyranose mutase. Chem Biol (2006) 1.19
Identification of inhibitors for UDP-galactopyranose mutase. J Am Chem Soc (2004) 1.19
Drug targeting Mycobacterium tuberculosis cell wall synthesis: development of a microtiter plate-based screen for UDP-galactopyranose mutase and identification of an inhibitor from a uridine-based library. Antimicrob Agents Chemother (2003) 1.14
Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth. J Am Chem Soc (2008) 1.12
Exploring the mechanism of binding of UDP-galactopyranose to UDP-galactopyranose mutase by STD-NMR spectroscopy and molecular modeling. Biochemistry (2005) 1.07
Improved chemical synthesis of UDP-galactofuranose. Org Lett (2001) 1.05
Synthesis and inhibition properties of conformational probes for the mutase-catalyzed UDP-galactopyranose/furanose interconversion. Chemistry (2003) 0.96
Synthesis and analysis of substrate analogues for UDP-galactopyranose mutase: implication for an oxocarbenium ion intermediate in the catalytic mechanism. Org Lett (2007) 0.93
Efficient synthesis of a nucleoside-diphospho-exo-glycal displaying time-dependent inactivation of UDP-galactopyranose mutase. Chem Commun (Camb) (2004) 0.83
Synthesis of novel ammonium and selenonium ions and their evaluation as inhibitors of UDP-galactopyranose mutase. Carbohydr Res (2004) 0.81
A Free-Wilson/Fujita-Ban analysis and prediction of the analgesic potency of some 3-hydroxy- and 3-methoxy-N-alkylmorphinan-6-one opioids. J Med Chem (1990) 0.80
An efficient synthesis of GDP-hexanolamine, a key tool for the purification of fucosyltransferases. Carbohydr Res (2002) 0.79
Influencing receptor-ligand binding mechanisms with multivalent ligand architecture. J Am Chem Soc (2002) 2.94
Inter-receptor communication through arrays of bacterial chemoreceptors. Nature (2002) 2.61
Trophoblast L-selectin-mediated adhesion at the maternal-fetal interface. Science (2003) 2.40
Selective tumor cell targeting using low-affinity, multivalent interactions. ACS Chem Biol (2007) 2.16
A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nat Methods (2010) 2.15
A unique catalytic mechanism for UDP-galactopyranose mutase. Nat Struct Mol Biol (2004) 2.15
Defined substrates for human embryonic stem cell growth identified from surface arrays. ACS Chem Biol (2007) 2.08
Surface plasmon resonance imaging studies of protein-carbohydrate interactions. J Am Chem Soc (2003) 1.96
Chemical probes of bacterial signal transduction reveal that repellents stabilize and attractants destabilize the chemoreceptor array. ACS Chem Biol (2008) 1.69
Activating B cell signaling with defined multivalent ligands. ACS Chem Biol (2007) 1.61
A polymeric domain that promotes cellular internalization. J Am Chem Soc (2008) 1.49
Control of multivalent interactions by binding epitope density. J Am Chem Soc (2002) 1.46
Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation. Proc Natl Acad Sci U S A (2009) 1.45
Arrays for the combinatorial exploration of cell adhesion. J Am Chem Soc (2004) 1.41
High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells. J Am Chem Soc (2010) 1.41
Large increases in attractant concentration disrupt the polar localization of bacterial chemoreceptors. Mol Microbiol (2005) 1.27
Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures. Protein Sci (2007) 1.24
Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal. ACS Nano (2012) 1.20
Chemical probes of UDP-galactopyranose mutase. Chem Biol (2006) 1.19
Identification of inhibitors for UDP-galactopyranose mutase. J Am Chem Soc (2004) 1.19
X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin. Biochemistry (2009) 1.18
General synthetic route to cell-permeable block copolymers via ROMP. J Am Chem Soc (2009) 1.14
Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues. Biochemistry (2007) 1.12
Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth. J Am Chem Soc (2008) 1.12
Selective immobilization of multivalent ligands for surface plasmon resonance and fluorescence microscopy. Anal Biochem (2002) 1.12
A polymer scaffold for protein oligomerization. J Am Chem Soc (2004) 1.11
A tethering mechanism for length control in a processive carbohydrate polymerization. Proc Natl Acad Sci U S A (2009) 1.10
Ligand binding and substrate discrimination by UDP-galactopyranose mutase. J Mol Biol (2009) 1.10
Synthesis of fluorogenic polymers for visualizing cellular internalization. Org Lett (2008) 1.03
Bifunctional ligands that target cells displaying the alpha v beta3 integrin. Chembiochem (2007) 1.03
Synthesis and applications of end-labeled neoglycopolymers. Org Lett (2002) 1.03
Solid-phase synthesis of polymers using the ring-opening metathesis polymerization. J Am Chem Soc (2005) 1.01
Synthetic glycoprotein mimics inhibit L-selectin-mediated rolling and promote L-selectin shedding. Chem Biol (2004) 1.00
Affinity-based inhibition of beta-amyloid toxicity. Biochemistry (2002) 0.99
Stereoselective N-glycosylation by Staudinger ligation. Org Lett (2004) 0.98
A strategy for the synthesis of sulfated peptides. Angew Chem Int Ed Engl (2002) 0.96
Synthesis of galactofuranose-based acceptor substrates for the study of the carbohydrate polymerase GlfT2. Bioorg Med Chem (2010) 0.95
New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography. Biochemistry (2014) 0.94
Phage display affords peptides that modulate beta-amyloid aggregation. J Am Chem Soc (2006) 0.94
Spatial control of cell fate using synthetic surfaces to potentiate TGF-beta signaling. Proc Natl Acad Sci U S A (2011) 0.94
Cell aggregation by scaffolded receptor clusters. Chem Biol (2002) 0.91
Synthesis of a multivalent display of a CD22-binding trisaccharide. Carbohydr Res (2002) 0.91
A processive carbohydrate polymerase that mediates bifunctional catalysis using a single active site. Biochemistry (2012) 0.91
Non-carbohydrate inhibitors of the lectin DC-SIGN. J Am Chem Soc (2007) 0.91
Monitoring processivity and length control of a carbohydrate polymerase. J Am Chem Soc (2011) 0.91
Conserved amplification of chemotactic responses through chemoreceptor interactions. J Bacteriol (2002) 0.90
Isotope-coded affinity tags with tunable reactivities for protein footprinting. Angew Chem Int Ed Engl (2008) 0.90
Fluorosugar chain termination agents as probes of the sequence specificity of a carbohydrate polymerase. J Am Chem Soc (2012) 0.90
Contrast agents for magnetic resonance imaging synthesized with ring-opening metathesis polymerization. J Am Chem Soc (2006) 0.89
Protein footprinting in a complex milieu: identifying the interaction surfaces of the chemotaxis adaptor protein CheW. J Mol Biol (2011) 0.89
Solid-phase synthesis of alkanethiols for the preparation of self-assembled monolayers. Langmuir (2007) 0.87
Structure-based design of a periplasmic binding protein antagonist that prevents domain closure. ACS Chem Biol (2009) 0.86
Parallel synthesis of glycomimetic libraries: targeting a C-type lectin. Org Lett (2003) 0.85
UDP-galactopyranose mutase in nematodes. Biochemistry (2013) 0.84
Noncarbohydrate glycomimetics and glycoprotein surrogates as DC-SIGN antagonists and agonists. ACS Chem Biol (2012) 0.83
Rhamnose glycoconjugates for the recruitment of endogenous anti-carbohydrate antibodies to tumor cells. Chembiochem (2014) 0.83
Synthesis of lipid-linked arabinofuranose donors for glycosyltransferases. J Org Chem (2013) 0.82
Synthesis of functionalizable and degradable polymers by ring-opening metathesis polymerization. Angew Chem Int Ed Engl (2013) 0.82
Small-molecule-modified surfaces engage cells through the αvβ3 integrin. ACS Chem Biol (2012) 0.82
Peptide ligands that use a novel binding site to target both TGF-β receptors. Mol Biosyst (2010) 0.82
A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN. Chem Commun (Camb) (2010) 0.81
Unexpected enhancement in biological activity of a GPCR ligand induced by an oligoethylene glycol substituent. J Am Chem Soc (2010) 0.81
Quinoxalinone Inhibitors of the Lectin DC-SIGN. Chem Sci (2011) 0.80
Isoprenoid phosphonophosphates as glycosyltransferase acceptor substrates. J Am Chem Soc (2014) 0.80
Synthetic antigens reveal dynamics of BCR endocytosis during inhibitory signaling. ACS Chem Biol (2013) 0.80
An asymmetric synthesis of L-pyrrolysine. Org Lett (2012) 0.78
ROMP from ROMP: A New Approach to Graft Copolymer Synthesis. Macromolecules (2009) 0.78
Glycomimetic building blocks: a divergent synthesis of epimers of shikimic acid. Org Lett (2011) 0.77
p-Methoxybenzyl ether cleavage by polymer-supported sulfonamides. Org Lett (2002) 0.77
Decoding signals with chemical biology. ACS Chem Biol (2010) 0.76
Link between chemotactic response to Ni2+ and its adsorption onto the Escherichia coli cell surface. Environ Sci Technol (2005) 0.76
Visualization and characterization of receptor clusters by transmission electron microscopy. Methods Enzymol (2003) 0.76
Classifying chemoreceptors: quantity versus quality. EMBO J (2010) 0.75
Flow cytometry reveals that multivalent chemoattractants effect swarmer cell dedifferentiation. ACS Chem Biol (2009) 0.75
Fostering major breakthroughs. ACS Chem Biol (2006) 0.75
A symposium in honor of Peter B. Dervan, the 2014 ACS Chemical Biology Lectureship Award Winner. ACS Chem Biol (2014) 0.75
ChemRXiv: A Chemistry Preprint Server. ACS Nano (2016) 0.75
A higher degree of difficulty. ACS Chem Biol (2007) 0.75
N-acylsulfonamide linker activation by Pd-catalyzed allylation. Org Lett (2006) 0.75
Nanoscience and Nanotechnology Cross Borders. ACS Nano (2017) 0.75
Improved chemical syntheses of 1- and 5-deazariboflavin. J Org Chem (2004) 0.75