Mark A Hanson

Author PubWeight™ 165.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Effect of in utero and early-life conditions on adult health and disease. N Engl J Med 2008 14.46
2 Living with the past: evolution, development, and patterns of disease. Science 2004 7.14
3 Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J Nutr 2005 4.57
4 Epigenetic mechanisms that underpin metabolic and cardiovascular diseases. Nat Rev Endocrinol 2009 3.25
5 Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes 2011 3.18
6 Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression. Hepatology 2009 3.11
7 Early life events and their consequences for later disease: a life history and evolutionary perspective. Am J Hum Biol 2006 3.02
8 Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications. Br J Nutr 2007 2.99
9 Predictive adaptive responses and human evolution. Trends Ecol Evol 2005 2.90
10 Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Br J Nutr 2008 2.55
11 The developmental origins of the metabolic syndrome. Trends Endocrinol Metab 2004 2.55
12 Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations. Br J Nutr 2007 2.48
13 Epigenetic mechanisms and the mismatch concept of the developmental origins of health and disease. Pediatr Res 2007 2.47
14 Environmental influences during development and their later consequences for health and disease: implications for the interpretation of empirical studies. Proc Biol Sci 2005 2.40
15 Towards a new developmental synthesis: adaptive developmental plasticity and human disease. Lancet 2009 2.35
16 Metabolic plasticity during mammalian development is directionally dependent on early nutritional status. Proc Natl Acad Sci U S A 2007 2.26
17 Developmental origins of disease paradigm: a mechanistic and evolutionary perspective. Pediatr Res 2004 2.11
18 Non-genomic transgenerational inheritance of disease risk. Bioessays 2007 2.07
19 The developmental origins of adult disease. Matern Child Nutr 2005 2.05
20 Gender-linked hypertension in offspring of lard-fed pregnant rats. Hypertension 2003 2.00
21 Epigenetic regulation of transcription: a mechanism for inducing variations in phenotype (fetal programming) by differences in nutrition during early life? Br J Nutr 2007 1.85
22 Developmental origins of metabolic disease: life course and intergenerational perspectives. Trends Endocrinol Metab 2010 1.78
23 Evolution, development and timing of puberty. Trends Endocrinol Metab 2005 1.75
24 Mechanisms of disease: in utero programming in the pathogenesis of hypertension. Nat Clin Pract Nephrol 2006 1.71
25 Maternal constraint of fetal growth and its consequences. Semin Fetal Neonatal Med 2004 1.70
26 Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition. J Nutr 2009 1.61
27 The role of developmental plasticity and epigenetics in human health. Birth Defects Res C Embryo Today 2011 1.55
28 Low birthweight and subsequent obesity in Japan. Lancet 2007 1.54
29 Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy. Am J Physiol Regul Integr Comp Physiol 2004 1.53
30 The fetal, neonatal, and infant environments-the long-term consequences for disease risk. Early Hum Dev 2004 1.45
31 The developmental origins, mechanisms, and implications of metabolic syndrome. J Nutr 2010 1.41
32 Cardiovascular and endocrine responses to cutaneous electrical stimulation after fentanyl in the ovine fetus. Am J Obstet Gynecol 2004 1.40
33 Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood. Proc Natl Acad Sci U S A 2007 1.36
34 Long-term maternal high-fat feeding from weaning through pregnancy and lactation predisposes offspring to hypertension, raised plasma lipids and fatty liver in mice. Br J Nutr 2009 1.29
35 Maternal protein restriction in the rat impairs resistance artery but not conduit artery function in pregnant offspring. J Physiol 2002 1.27
36 Life-long echoes--a critical analysis of the developmental origins of adult disease model. Biol Neonate 2004 1.26
37 Adaptive responses by mouse early embryos to maternal diet protect fetal growth but predispose to adult onset disease. Biol Reprod 2007 1.25
38 Endothelial dysfunction and reduced antioxidant protection in an animal model of the developmental origins of cardiovascular disease. J Physiol 2008 1.23
39 Folate supplementation during pregnancy improves offspring cardiovascular dysfunction induced by protein restriction. Hypertension 2006 1.20
40 Progressive, transgenerational changes in offspring phenotype and epigenotype following nutritional transition. PLoS One 2011 1.18
41 The nature of the growth pattern and of the metabolic response to fasting in the rat are dependent upon the dietary protein and folic acid intakes of their pregnant dams and post-weaning fat consumption. Br J Nutr 2007 1.14
42 Early-life prevention of non-communicable diseases. Lancet 2013 1.14
43 Developmental origins of health and disease: reducing the burden of chronic disease in the next generation. Genome Med 2010 1.13
44 Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring. J Physiol 2008 1.12
45 Prenatal programming of postnatal endocrine responses by glucocorticoids. Reproduction 2002 1.11
46 The long-term effects of prenatal development on growth and metabolism. Semin Reprod Med 2011 1.10
47 Maternal protein restriction with or without folic acid supplementation during pregnancy alters the hepatic transcriptome in adult male rats. Br J Nutr 2010 1.10
48 Fetal and neonatal pathways to obesity. Front Horm Res 2008 1.08
49 Transgenerational effects of prenatal nutrient restriction on cardiovascular and hypothalamic-pituitary-adrenal function. J Physiol 2008 1.08
50 An unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth. Clin Endocrinol (Oxf) 2012 1.04
51 Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver. J Nutr Biochem 2012 1.03
52 High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep. Am J Physiol Regul Integr Comp Physiol 2007 1.01
53 Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases. Epigenomics 2011 1.01
54 Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis. PLoS One 2012 1.00
55 Peri-implantation and late gestation maternal undernutrition differentially affect fetal sheep skeletal muscle development. J Physiol 2008 1.00
56 Human growth: evolutionary and life history perspectives. Nestle Nutr Inst Workshop Ser 2013 0.99
57 Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice. PLoS One 2012 0.99
58 Dietary protein restriction during F0 pregnancy in rats induces transgenerational changes in the hepatic transcriptome in female offspring. PLoS One 2011 0.98
59 Does estrogen affect the development of abnormal vascular function in offspring of rats fed a low-protein diet in pregnancy? Pediatr Res 2006 0.98
60 Modification of fetal plasma amino acid composition by placental amino acid exchangers in vitro. J Physiol 2007 0.98
61 Atorvastatin restores endothelial function in offspring of protein-restricted rats in a cholesterol-independent manner. Hypertension 2009 0.96
62 Predictive adaptive responses in perspective. Trends Endocrinol Metab 2008 0.96
63 Statin treatment in hypercholesterolemic pregnant mice reduces cardiovascular risk factors in their offspring. Hypertension 2008 0.95
64 Effect of nutritional restriction in early pregnancy on isolated femoral artery function in mid-gestation fetal sheep. J Physiol 2003 0.93
65 Prenatal factors contribute to the emergence of kwashiorkor or marasmus in severe undernutrition: evidence for the predictive adaptation model. PLoS One 2012 0.92
66 Transmission of raised blood pressure and endothelial dysfunction to the F2 generation induced by maternal protein restriction in the F0, in the absence of dietary challenge in the F1 generation. Br J Nutr 2008 0.91
67 Sex- and age-specific effects of nutrition in early gestation and early postnatal life on hypothalamo-pituitary-adrenal axis and sympathoadrenal function in adult sheep. J Physiol 2010 0.91
68 Associations between DNA methylation of a glucocorticoid receptor promoter and acute stress responses in a large healthy adult population are largely explained by lifestyle and educational differences. Psychoneuroendocrinology 2011 0.91
69 Developmental origins of the metabolic syndrome: body clocks and stress responses. Brain Behav Immun 2010 0.91
70 Maternal undernutrition leads to endothelial dysfunction in adult male rat offspring independent of postnatal diet. Br J Nutr 2008 0.91
71 Fetal liver blood flow distribution: role in human developmental strategy to prioritize fat deposition versus brain development. PLoS One 2012 0.90
72 A 200-year perspective on alternative stable state theory and lake management from a biomanipulated shallow lake. Ecol Appl 2012 0.90
73 Fetal size in the second trimester is associated with the duration of pregnancy, small fetuses having longer pregnancies. BMC Pregnancy Childbirth 2008 0.89
74 Vasodilation to vascular endothelial growth factor in the uterine artery of the pregnant rat is blunted by low dietary protein intake. Pediatr Res 2002 0.89
75 Increasing the folic acid content of maternal or post-weaning diets induces differential changes in phosphoenolpyruvate carboxykinase mRNA expression and promoter methylation in rats. Br J Nutr 2011 0.88
76 Effects of chronic hypoxia and protein malnutrition on growth in the developing chick. Am J Obstet Gynecol 2002 0.87
77 Childhood bone mineral content is associated with methylation status of the RXRA promoter at birth. J Bone Miner Res 2014 0.86
78 The effect of maternal undernutrition in early gestation on gestation length and fetal and postnatal growth in sheep. Pediatr Res 2007 0.86
79 Maternal low-protein diet during mouse pre-implantation development induces vascular dysfunction and altered renin-angiotensin-system homeostasis in the offspring. Br J Nutr 2010 0.86
80 Effect of reduced maternal protein intake in pregnancy in the rat on the fatty acid composition of brain, liver, plasma, heart and lung phospholipids of the offspring after weaning. Br J Nutr 2003 0.86
81 Aquatic persistence of eight pharmaceuticals in a microcosm study. Environ Toxicol Chem 2004 0.85
82 The fetal llama versus the fetal sheep: different strategies to withstand hypoxia. High Alt Med Biol 2003 0.85
83 Nutritional challenges during development induce sex-specific changes in glucose homeostasis in the adult sheep. Am J Physiol Endocrinol Metab 2006 0.84
84 Hepatic artery hemodynamics suggest operation of a buffer response in the human fetus. Reprod Sci 2008 0.84
85 Effects of pre-natal and early post-natal undernutrition on adult internal thoracic artery function. Eur J Cardiothorac Surg 2005 0.83
86 Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply. J Clin Endocrinol Metab 2004 0.83
87 Role of DNA methyltransferase 1 on the altered eNOS expression in human umbilical endothelium from intrauterine growth restricted fetuses. Epigenetics 2013 0.82
88 The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. Biochim Biophys Acta 2004 0.82
89 Effects of pre- and periconceptional undernutrition on arterial function in adult female sheep are vascular bed dependent. Exp Physiol 2009 0.82
90 Nitric oxide plays a role in the regulation of adrenal blood flow and adrenocorticomedullary functions in the llama fetus. J Physiol 2002 0.82
91 Appetite regulatory mechanisms and food intake in mice are sensitive to mismatch in diets between pregnancy and postnatal periods. Brain Res 2008 0.81
92 Umbilical venous-arterial plasma composition differences suggest differential incorporation of fatty acids in NEFA and cholesteryl ester pools. Br J Nutr 2011 0.81
93 The effect of systemic administration of lipopolysaccharide on cerebral haemodynamics and oxygenation in the 0.65 gestation ovine fetus in utero. BJOG 2003 0.81
94 Effect of maternal protein restriction during pregnancy and postweaning high-fat feeding on diet-induced thermogenesis in adult mouse offspring. Eur J Nutr 2014 0.80
95 Glucose metabolism in adult survivors of severe acute malnutrition. J Clin Endocrinol Metab 2014 0.80
96 Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano. Cardiovasc Res 2007 0.80
97 Expression of agouti-related peptide, neuropeptide Y, pro-opiomelanocortin and the leptin receptor isoforms in fetal mouse brain from pregnant dams on a protein-restricted diet. Brain Res Mol Brain Res 2005 0.80
98 The late gestation fetal cardiovascular response to hypoglycaemia is modified by prior peri-implantation undernutrition in sheep. J Physiol 2008 0.79
99 Non-imprinted epigenetics in fetal and postnatal development and growth. Nestle Nutr Inst Workshop Ser 2013 0.79
100 Macrophytes in shallow lakes: relationships with water, sediment and watershed characteristics. 2013 0.79
101 The fetal dilemma: spare the brain and spoil the liver. J Physiol 2003 0.78
102 Effect of sex and dietary fat intake on the fatty acid composition of phospholipids and triacylglycerol in rat heart. Prostaglandins Leukot Essent Fatty Acids 2010 0.78
103 Sensitivity of housekeeping genes in the hypothalamus to mismatch in diets between pre- and postnatal periods in mice. Neurosci Lett 2008 0.78
104 Evolving in thin air--lessons from the llama fetus in the altiplano. Respir Physiol Neurobiol 2007 0.78
105 Relative importance of phosphorus, fish biomass, and watershed land use as drivers of phytoplankton abundance in shallow lakes. Sci Total Environ 2013 0.78
106 Correction: The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight. PLoS Med 2017 0.77
107 Fetal superior mesenteric artery: longitudinal reference ranges and evidence of regulatory link to portal liver circulation. Early Hum Dev 2008 0.77
108 Fetal origins of coronary heart disease-implications for cardiothoracic surgery? Eur J Cardiothorac Surg 2005 0.77
109 Angiotensin II receptor antagonist reduces subsequent uterine arterial dysfunction in pregnant offspring of protein-restricted rat dams. J Obstet Gynaecol Res 2012 0.77
110 Metabolic disease: evolutionary, developmental and transgenerational influences. Nestle Nutr Workshop Ser Pediatr Program 2005 0.77
111 The effect of maternal body condition score before and during pregnancy on the glucose tolerance of adult sheep offspring. Reprod Sci 2008 0.77
112 Vascular, renal and placental effects on pregnant offspring of protein-restricted rat dams. J Obstet Gynaecol Res 2011 0.76
113 Developmental perspectives on individual variation: implications for understanding nutritional needs. Nestle Nutr Workshop Ser Pediatr Program 2008 0.76
114 Vasodilator tone in the llama fetus: the role of nitric oxide during normoxemia and hypoxemia. Am J Physiol Regul Integr Comp Physiol 2005 0.76
115 Association of adult height and leg length with fasting plasma cortisol concentrations: evidence for an effect of normal variation in adrenocortical activity on growth. Am J Hum Biol 2008 0.76
116 Gestational diabetes, maternal obesity, and the NCD burden. Clin Obstet Gynecol 2013 0.76
117 Tissue-specific 5' heterogeneity of PPARα transcripts and their differential regulation by leptin. PLoS One 2013 0.76
118 Lower maternal body condition during pregnancy affects skeletal muscle structure and glut-4 protein levels but not glucose tolerance in mature adult sheep. Reprod Sci 2013 0.75
119 Redistribution pattern of fetal liver circulation in intrauterine growth restriction. Acta Obstet Gynecol Scand 2009 0.75
120 Correction: Fat and Carbohydrate Intake over Three Generations Modify Growth, Metabolism and Cardiovascular Phenotype in Female Mice in an Age-Related Manner. PLoS One 2017 0.75
121 Developmental origins of obesity and non-communicable disease. Endocrinol Nutr 2013 0.75