Published in J Am Chem Soc on January 14, 2009
eNOS activation and NO function: structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity. J Endocrinol (2011) 1.60
Active intermediates in heme monooxygenase reactions as revealed by cryoreduction/annealing, EPR/ENDOR studies. Arch Biochem Biophys (2010) 1.10
NADPH-cytochrome P450 oxidoreductase: prototypic member of the diflavin reductase family. Arch Biochem Biophys (2012) 1.00
The critical iron-oxygen intermediate in human aromatase. Biochem Biophys Res Commun (2009) 0.98
NO formation by a catalytically self-sufficient bacterial nitric oxide synthase from Sorangium cellulosum. Proc Natl Acad Sci U S A (2009) 0.92
Development of novel arginase inhibitors for therapy of endothelial dysfunction. Front Immunol (2013) 0.89
Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation. J Biol Chem (2009) 0.87
Electron paramagnetic resonance characterization of tetrahydrobiopterin radical formation in bacterial nitric oxide synthase compared to mammalian nitric oxide synthase. Biophys J (2012) 0.85
Characterization of a thiolato iron(III) Peroxy dianion complex. Angew Chem Int Ed Engl (2012) 0.83
Gating NO release from nitric oxide synthase. J Am Chem Soc (2011) 0.80
Kinetic solvent isotope effect in steady-state turnover by CYP19A1 suggests involvement of Compound 1 for both hydroxylation and aromatization steps. FEBS Lett (2014) 0.80
Catalytic intermediates of inducible nitric-oxide synthase stabilized by the W188H mutation. J Biol Chem (2012) 0.80
Methylated N(ω)-hydroxy-L-arginine analogues as mechanistic probes for the second step of the nitric oxide synthase-catalyzed reaction. Biochemistry (2013) 0.78
Enzymatic and cryoreduction EPR studies of the hydroxylation of methylated N(ω)-hydroxy-L-arginine analogues by nitric oxide synthase from Geobacillus stearothermophilus. Biochemistry (2014) 0.78
Reaction of N-hydroxyguanidine with the ferrous-oxy state of a heme peroxidase cavity mutant: a model for the reactions of nitric oxide synthase. Arch Biochem Biophys (2010) 0.78
Probing the Hydrogen Bonding of the Ferrous-NO Heme Center of nNOS by Pulsed Electron Paramagnetic Resonance. J Phys Chem A (2015) 0.76
Probing 'spin-forbidden' oxygen-atom transfer: gas-phase reactions of chromium-porphyrin complexes. J Am Chem Soc (2010) 0.75
Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature (2004) 5.09
A distributed chemosensory circuit for oxygen preference in C. elegans. PLoS Biol (2006) 2.95
Cellobiose dehydrogenase and a copper-dependent polysaccharide monooxygenase potentiate cellulose degradation by Neurospora crassa. ACS Chem Biol (2011) 2.76
Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine. Nat Chem Biol (2005) 2.60
Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases. Structure (2012) 2.51
Oxidative cleavage of cellulose by fungal copper-dependent polysaccharide monooxygenases. J Am Chem Soc (2011) 2.45
Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases. Proc Natl Acad Sci U S A (2004) 2.41
A molecular basis for NO selectivity in soluble guanylate cyclase. Nat Chem Biol (2005) 2.34
Systems analysis of plant cell wall degradation by the model filamentous fungus Neurospora crassa. Proc Natl Acad Sci U S A (2009) 2.17
Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases. Neuron (2009) 2.14
Assembly of the covalent linkage between lipoic acid and its cognate enzymes. Chem Biol (2003) 2.11
N-terminal processing of proteins exported by malaria parasites. Mol Biochem Parasitol (2008) 1.81
Spectroscopic characterization of the soluble guanylate cyclase-like heme domains from Vibrio cholerae and Thermoanaerobacter tengcongensis. Biochemistry (2004) 1.80
Nitric oxide signaling: no longer simply on or off. Trends Biochem Sci (2006) 1.79
Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism. Anal Chem (2013) 1.76
Two-peptide bacteriocins produced by lactic acid bacteria. Biochimie (2002) 1.72
Structure and regulation of soluble guanylate cyclase. Annu Rev Biochem (2012) 1.72
Design and characterization of an active site selective caspase-3 transnitrosating agent. ACS Chem Biol (2006) 1.67
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells. Proc Natl Acad Sci U S A (2007) 1.52
Expression and characterization of the catalytic domains of soluble guanylate cyclase: interaction with the heme domain. Biochemistry (2005) 1.48
Biochemistry of soluble guanylate cyclase. Handb Exp Pharmacol (2009) 1.47
Interference with heme binding to histidine-rich protein-2 as an antimalarial strategy. Chem Biol (2002) 1.42
Probing the function of heme distortion in the H-NOX family. ACS Chem Biol (2008) 1.42
Ligand specificity of H-NOX domains: from sGC to bacterial NO sensors. J Inorg Biochem (2005) 1.32
Mycobacteria inhibit nitric oxide synthase recruitment to phagosomes during macrophage infection. Infect Immun (2004) 1.31
Metal binding characteristics and role of iron oxidation in the ferric uptake regulator from Escherichia coli. Biochemistry (2005) 1.28
Ligand discrimination in soluble guanylate cyclase and the H-NOX family of heme sensor proteins. Curr Opin Chem Biol (2005) 1.28
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase. BMC Struct Biol (2008) 1.26
Nitric oxide modulates bacterial biofilm formation through a multicomponent cyclic-di-GMP signaling network. Mol Cell (2012) 1.25
Quantitative proteomic approach for cellulose degradation by Neurospora crassa. J Proteome Res (2011) 1.25
Tonic and acute nitric oxide signaling through soluble guanylate cyclase is mediated by nonheme nitric oxide, ATP, and GTP. Proc Natl Acad Sci U S A (2005) 1.24
Determinants of regioselective hydroxylation in the fungal polysaccharide monooxygenases. J Am Chem Soc (2013) 1.23
A structural basis for H-NOX signaling in Shewanella oneidensis by trapping a histidine kinase inhibitory conformation. Proc Natl Acad Sci U S A (2009) 1.22
Characterization of functional heme domains from soluble guanylate cyclase. Biochemistry (2005) 1.21
Mechanisms of S-nitrosothiol formation and selectivity in nitric oxide signaling. Curr Opin Chem Biol (2012) 1.19
Shewanella oneidensis MR-1 H-NOX regulation of a histidine kinase by nitric oxide. Biochemistry (2007) 1.18
Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructs. J Biol Chem (2006) 1.16
Subcellular targeting and differential S-nitrosylation of endothelial nitric-oxide synthase. J Biol Chem (2005) 1.16
An Escherichia coli expression-based method for heme substitution. Nat Methods (2006) 1.15
A nitric oxide/cysteine interaction mediates the activation of soluble guanylate cyclase. Proc Natl Acad Sci U S A (2009) 1.14
Nitric oxide binding to prokaryotic homologs of the soluble guanylate cyclase beta1 H-NOX domain. J Biol Chem (2006) 1.13
Cellulose degradation by polysaccharide monooxygenases. Annu Rev Biochem (2015) 1.11
Sre1, an iron-modulated GATA DNA-binding protein of iron-uptake genes in the fungal pathogen Histoplasma capsulatum. Biochemistry (2008) 1.08
H-NOX-mediated nitric oxide sensing modulates symbiotic colonization by Vibrio fischeri. Proc Natl Acad Sci U S A (2010) 1.06
Higher-order interactions bridge the nitric oxide receptor and catalytic domains of soluble guanylate cyclase. Proc Natl Acad Sci U S A (2013) 1.05
Heme binding to the histidine-rich protein II from Plasmodium falciparum. Biochemistry (2005) 1.05
Reactions catalyzed by the heme domain of inducible nitric oxide synthase: evidence for the involvement of tetrahydrobiopterin in electron transfer. Biochemistry (2002) 1.04
S-Nitrosation and regulation of inducible nitric oxide synthase. Biochemistry (2005) 1.02
Characterization of two different five-coordinate soluble guanylate cyclase ferrous-nitrosyl complexes. Biochemistry (2008) 1.01
Modulating heme redox potential through protein-induced porphyrin distortion. J Am Chem Soc (2010) 1.01
Site-specific and redox-controlled S-nitrosation of thioredoxin. Proc Natl Acad Sci U S A (2011) 1.01
Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation. Proc Natl Acad Sci U S A (2013) 1.00
Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: formation of a pterin radical is required for enzyme activity. Biochemistry (2003) 0.99
Ru-porphyrin protein scaffolds for sensing O2. J Am Chem Soc (2010) 0.99
Biochemical evidence for an alternate pathway in N-linked glycoprotein biosynthesis. Nat Chem Biol (2013) 0.97
Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain. Proc Natl Acad Sci U S A (2011) 0.95
Resonance Raman spectra of an O2-binding H-NOX domain reveal heme relaxation upon mutation. Biochemistry (2009) 0.95
Nucleotide regulation of soluble guanylate cyclase substrate specificity. Biochemistry (2009) 0.95
A novel in vivo cell-wall labeling approach sheds new light on peptidoglycan synthesis in Escherichia coli. Chembiochem (2011) 0.95
Ligand binding and inhibition of an oxygen-sensitive soluble guanylate cyclase, Gyc-88E, from Drosophila. Biochemistry (2007) 0.94
Pterin-centered radical as a mechanistic probe of the second step of nitric oxide synthase. J Am Chem Soc (2010) 0.93
Butyl isocyanide as a probe of the activation mechanism of soluble guanylate cyclase. Investigating the role of non-heme nitric oxide. J Biol Chem (2007) 0.93
Revisiting the kinetics of nitric oxide (NO) binding to soluble guanylate cyclase: the simple NO-binding model is incorrect. Proc Natl Acad Sci U S A (2002) 0.93
NO formation by a catalytically self-sufficient bacterial nitric oxide synthase from Sorangium cellulosum. Proc Natl Acad Sci U S A (2009) 0.92
Determinants of ligand affinity and heme reactivity in H-NOX domains. Angew Chem Int Ed Engl (2010) 0.92
Nη-substituted arginyl peptide inhibitors of protein arginine N-methyltransferases. ACS Chem Biol (2010) 0.92
Nitric oxide synthase stabilizes the tetrahydrobiopterin cofactor radical by controlling its protonation state. J Am Chem Soc (2010) 0.92
Probing soluble guanylate cyclase activation by CO and YC-1 using resonance Raman spectroscopy. Biochemistry (2010) 0.91
Metal stoichiometry and functional studies of the diphtheria toxin repressor. Proc Natl Acad Sci U S A (2003) 0.91
Synthesis of nitric oxide by the NOS-like protein from deinococcus radiodurans: a direct role for tetrahydrofolate. Biochemistry (2009) 0.90
Effects of nitroglycerin on soluble guanylate cyclase: implications for nitrate tolerance. J Biol Chem (2002) 0.90
Structure and properties of a bis-histidyl ligated globin from Caenorhabditis elegans. Biochemistry (2010) 0.89
Synthesis and evaluation of protein arginine N-methyltransferase inhibitors designed to simultaneously occupy both substrate binding sites. Org Biomol Chem (2015) 0.89
Extracellular aldonolactonase from Myceliophthora thermophila. Appl Environ Microbiol (2010) 0.89
Design and synthesis of C5 methylated L-arginine analogues as active site probes for nitric oxide synthase. J Am Chem Soc (2007) 0.89
Structural insights into the molecular mechanism of H-NOX activation. Protein Sci (2010) 0.88
Use of a semisynthetic epitope to probe histidine kinase activity and regulation. Anal Biochem (2009) 0.88
Incorporation of tyrosine and glutamine residues into the soluble guanylate cyclase heme distal pocket alters NO and O2 binding. J Biol Chem (2010) 0.87
Multiple on-resin olefin metathesis to form ring-expanded analogues of the lantibiotic peptide, lacticin 3147 A2. Org Lett (2007) 0.87
Characterization of nitrosoalkane binding and activation of soluble guanylate cyclase. Biochemistry (2005) 0.87
Nitric oxide-sensing H-NOX proteins govern bacterial communal behavior. Trends Biochem Sci (2013) 0.86
Expression and characterization of the Neurospora crassa endoglucanase GH5-1. Protein Expr Purif (2010) 0.86
Sensitive and selective detection of nitric oxide using an H-NOX domain. J Am Chem Soc (2006) 0.86
Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase. Proc Natl Acad Sci U S A (2014) 0.85
Heme-assisted S-nitrosation desensitizes ferric soluble guanylate cyclase to nitric oxide. J Biol Chem (2012) 0.84
Production of piscicolin 126 by Carnobacterium maltaromaticum UAL26 is controlled by temperature and induction peptide concentration. Arch Microbiol (2006) 0.84
Mechanism and kinetics of inducible nitric oxide synthase auto-S-nitrosation and inactivation. Biochemistry (2012) 0.83
Peptidic partial bisubstrates as inhibitors of the protein arginine N-methyltransferases. Chembiochem (2011) 0.83
Probing domain interactions in soluble guanylate cyclase. Biochemistry (2011) 0.82
Calcium-binding sites of calmodulin and electron transfer by inducible nitric oxide synthase. Biochemistry (2005) 0.82
Redox couples of inducible nitric oxide synthase. J Am Chem Soc (2005) 0.82
Insight into the rescue of oxidized soluble guanylate cyclase by the activator cinaciguat. Chembiochem (2012) 0.81
Soluble guanylate cyclase is activated differently by excess NO and by YC-1: resonance Raman spectroscopic evidence. Biochemistry (2010) 0.81
Inhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamers. Proc Natl Acad Sci U S A (2009) 0.81
L-arginine analogs as alternate substrates for nitric oxide synthase. Bioorg Med Chem Lett (2005) 0.80
Determinants of the heme-CO vibrational modes in the H-NOX family. Biochemistry (2011) 0.80
The design and synthesis of YC-1 analogues as probes for soluble guanylate cyclase. Bioorg Med Chem Lett (2005) 0.79
Amino acid substitution and modification resulting from Escherichia coli expression of recombinant Plasmodium falciparum histidine-rich protein II. Biochemistry (2005) 0.79
4,4-Difluorinated analogues of l-arginine and N(G)-hydroxy-l-arginine as mechanistic probes for nitric oxide synthase. Bioorg Med Chem Lett (2009) 0.79