Published in Circulation on February 02, 2009
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Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning. Proc Natl Acad Sci U S A (2007) 1.61
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Heme oxygenase-1 and its reaction product, carbon monoxide, prevent inflammation-related apoptotic liver damage in mice. Hepatology (2003) 1.52
Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia. Diabetes (2002) 1.51
Carbon monoxide inhibits sprouting angiogenesis and vascular endothelial growth factor receptor-2 phosphorylation. Thromb Haemost (2014) 1.48
A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation. Blood (2004) 1.37
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Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells. Am J Physiol Renal Physiol (2009) 1.28
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MARCKS silencing differentially affects human vascular smooth muscle and endothelial cell phenotypes to inhibit neointimal hyperplasia in saphenous vein. FASEB J (2008) 1.28
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Therapeutic applications of bilirubin and biliverdin in transplantation. Antioxid Redox Signal (2007) 1.24
Cooperative effect of biliverdin and carbon monoxide on survival of mice in immune-mediated liver injury. Hepatology (2004) 1.24
Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection. PLoS Pathog (2008) 1.22
Cell surface biliverdin reductase mediates biliverdin-induced anti-inflammatory effects via phosphatidylinositol 3-kinase and Akt. J Biol Chem (2009) 1.20
Upregulation of CD39/NTPDases and P2 receptors in human pancreatic disease. Am J Physiol Gastrointest Liver Physiol (2006) 1.19
A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis. Hepatology (2002) 1.17
Carbon monoxide reverses established pulmonary hypertension. J Exp Med (2006) 1.14
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Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells. J Biol Chem (2004) 1.10
A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia. FASEB J (2006) 1.09
Extracellular nucleotides and adenosine independently activate AMP-activated protein kinase in endothelial cells: involvement of P2 receptors and adenosine transporters. Circ Res (2006) 1.08
Acute vascular rejection of xenografts: roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity. Transplantation (2004) 1.07
On the intraoperative molecular status of renal allografts after vascular reperfusion and clinical outcomes. J Am Soc Nephrol (2005) 1.07
A20 promotes liver regeneration by decreasing SOCS3 expression to enhance IL-6/STAT3 proliferative signals. Hepatology (2013) 1.06
Heme oxygenase-1 promotes survival of renal cancer cells through modulation of apoptosis- and autophagy-regulating molecules. J Biol Chem (2012) 1.05
RanBPM associates with CD39 and modulates ecto-nucleotidase activity. Biochem J (2006) 1.05
Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species. Arterioscler Thromb Vasc Biol (2010) 1.04
Genetic engineering of a suboptimal islet graft with A20 preserves beta cell mass and function. J Immunol (2003) 1.03
Biliverdin inhibits Toll-like receptor-4 (TLR4) expression through nitric oxide-dependent nuclear translocation of biliverdin reductase. Proc Natl Acad Sci U S A (2011) 1.02
Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation. J Clin Invest (2014) 1.00
O-glycosylation regulates ubiquitination and degradation of the anti-inflammatory protein A20 to accelerate atherosclerosis in diabetic ApoE-null mice. PLoS One (2010) 1.00
A novel function for cadherin 11/osteoblast-cadherin in vascular smooth muscle cells: modulation of cell migration and proliferation. J Vasc Surg (2007) 0.98
A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21waf1-dependent mechanism. Hepatology (2005) 0.97
A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis. Circulation (2003) 0.96
Expression of A20 in the vessel wall of rat-kidney allografts correlates with protection from transplant arteriosclerosis. Transplantation (2003) 0.95
Expression of protective genes in human renal allografts: a regulatory response to injury associated with graft rejection. Transplantation (2002) 0.95
Functional dichotomy of A20 in apoptotic and necrotic cell death. Biochem J (2005) 0.95
Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages. J Immunol (2007) 0.95
A20 modulates lipid metabolism and energy production to promote liver regeneration. PLoS One (2011) 0.94
Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice. Transplantation (2004) 0.92
A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression. Liver Transpl (2009) 0.92
Molecular biomarkers of vascular dysfunction in obstructive sleep apnea. PLoS One (2013) 0.92
TNFalpha-induced macrophage death via caspase-dependent and independent pathways. Apoptosis (2009) 0.91
A20 inhibits post-angioplasty restenosis by blocking macrophage trafficking and decreasing adventitial neovascularization. Atherosclerosis (2010) 0.91
Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells. Kidney Int (2005) 0.87
Adenosine A1 receptors promote vasa vasorum endothelial cell barrier integrity via Gi and Akt-dependent actin cytoskeleton remodeling. PLoS One (2013) 0.87
Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells. Angiogenesis (2011) 0.87
Temporal network based analysis of cell specific vein graft transcriptome defines key pathways and hub genes in implantation injury. PLoS One (2012) 0.86
Induction of protective genes leads to islet survival and function. J Transplant (2011) 0.85
Mitochondrial damage-associated molecular patterns from fractures suppress pulmonary immune responses via formyl peptide receptors 1 and 2. J Trauma Acute Care Surg (2015) 0.84
Heme oxygenase-1 and carbon monoxide modulate DNA repair through ataxia-telangiectasia mutated (ATM) protein. Proc Natl Acad Sci U S A (2011) 0.84
Single nucleotide polymorphisms at the TNFAIP3/A20 locus and susceptibility/resistance to inflammatory and autoimmune diseases. Adv Exp Med Biol (2014) 0.84
A20--an omnipotent protein in the liver: prometheus myth resolved? Adv Exp Med Biol (2014) 0.83
Increased frequencies of CD8+ T lymphocytes recognizing wild-type p53-derived epitopes in peripheral blood correlate with presence of epitope loss tumor variants in patients with hepatocellular carcinoma. Int J Cancer (2006) 0.83
Valsartan improves resting skin blood flow in type 2 diabetic patients and reduces poly(adenosine diphosphate-ribose) polymerase activation. J Vasc Surg (2006) 0.83
A20 deficiency causes spontaneous neuroinflammation in mice. J Neuroinflammation (2014) 0.82
A20 expressing tumors and anticancer drug resistance. Adv Exp Med Biol (2014) 0.81
A20-mediated modulation of inflammatory and immune responses in aortic allografts and development of transplant arteriosclerosis. Transplantation (2012) 0.81
New strategies for cardiovascular gene therapy: regulatable pre-emptive expression of pro-angiogenic and antioxidant genes. Cell Biochem Biophys (2006) 0.81
Urinary excretion of soluble tumour necrosis factor receptor 1 as a marker of increased risk of progressive kidney function deterioration in patients with primary chronic glomerulonephritis. Nephrol Dial Transplant (2010) 0.80
Is mesangial hypercellularity with glomerular immaturity a variant of glomerulosclerosis? Pediatr Nephrol (2007) 0.79
Impact of p53-based immunization on primary chemically-induced tumors. Int J Cancer (2005) 0.79
Hepatocyte growth factor preferentially activates the anti-inflammatory arm of NF-κB signaling to induce A20 and protect renal proximal tubular epithelial cells from inflammation. J Cell Physiol (2012) 0.79
Electron-microscopic and immunohistochemical study in Henoch-Schoenlein nephritis. Ultrastruct Pathol (2013) 0.79
Potential target molecules on pig kidneys recognized by naïve and elicited baboon antibodies. Xenotransplantation (2004) 0.79
Anti-viral tetris: modulation of the innate anti-viral immune response by A20. Adv Exp Med Biol (2014) 0.78
Elevated urinary fibronectin excretion predicts poor outcome in patients with primary chronic glomerulonephritis. Nephron Clin Pract (2010) 0.78
Translational studies of A20 in atherosclerosis and cardiovascular disease. Adv Exp Med Biol (2014) 0.78
Expression of angiogenesis-stimulating factors (VEGF, CD31, CD105) and angiogenetic index in gingivae of patients with chronic periodontitis. Folia Histochem Cytobiol (2012) 0.78
Endothelial cells are susceptible to rapid siRNA transfection and gene silencing ex vivo. J Vasc Surg (2010) 0.78
Calcium-modulating cyclophilin ligand does not restrict retrovirus release. Nat Med (2010) 0.78
The prognosis of clinical course and the analysis of the frequency of the inflammation and dysplasia in the intestinal J-pouch at the patients after restorative proctocolectomy due to FAP. Int J Colorectal Dis (2011) 0.77
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The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cells. Biochim Biophys Acta (2013) 0.77
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Relative effects of GAL+ and GALlow/- porcine hematopoietic cells on primate platelet aggregation and endothelial cell activation: implications for the induction of mixed hematopoietic chimerism in the pig-to-primate model. Xenotransplantation (2004) 0.75
A20 Haploinsufficiency Aggravates Transplant Arteriosclerosis in Mouse Vascular Allografts: Implications for Clinical Transplantation. Transplantation (2016) 0.75
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Bilirubin suppresses Th17 immunity in colitis by upregulating CD39. JCI Insight (2017) 0.75
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