Published in Mol Cell Proteomics on February 06, 2009
The genetic interpretation of area under the ROC curve in genomic profiling. PLoS Genet (2010) 4.58
Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT). Ophthalmology (2013) 2.82
Mechanisms of age-related macular degeneration. Neuron (2012) 2.62
Aging is not a disease: distinguishing age-related macular degeneration from aging. Prog Retin Eye Res (2013) 1.29
The Human Eye Proteome Project: perspectives on an emerging proteome. Proteomics (2013) 1.23
Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes. Mol Cell Proteomics (2010) 1.22
Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy. Prog Retin Eye Res (2014) 1.17
Genetics of age-related macular degeneration: current concepts, future directions. Semin Ophthalmol (2011) 1.16
A randomized pilot study of systemic immunosuppression in the treatment of age-related macular degeneration with choroidal neovascularization. Retina (2010) 1.14
Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration. Mol Cell Proteomics (2009) 1.08
Isolevuglandins covalently modify phosphatidylethanolamines in vivo: detection and quantitative analysis of hydroxylactam adducts. Free Radic Biol Med (2009) 1.06
Discovery of carboxyethylpyrroles (CEPs): critical insights into AMD, autism, cancer, and wound healing from basic research on the chemistry of oxidized phospholipids. Chem Res Toxicol (2011) 1.05
Complement dysregulation in AMD: RPE-Bruch's membrane-choroid. Mol Aspects Med (2012) 1.03
Long-chain and very long-chain polyunsaturated fatty acids in ocular aging and age-related macular degeneration. J Lipid Res (2010) 1.03
Plasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration. Am J Ophthalmol (2011) 0.97
Cone structure imaged with adaptive optics scanning laser ophthalmoscopy in eyes with nonneovascular age-related macular degeneration. Invest Ophthalmol Vis Sci (2013) 0.97
Detection and biological activities of carboxyethylpyrrole ethanolamine phospholipids (CEP-EPs). Chem Res Toxicol (2014) 0.95
Role of ocular complement factor H in a murine model of choroidal neovascularization. Am J Pathol (2010) 0.95
The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages. PLoS One (2014) 0.94
CEP biomarkers as potential tools for monitoring therapeutics. PLoS One (2013) 0.92
Multiplex analysis of age-related protein and lipid modifications in human Bruch's membrane. FASEB J (2010) 0.89
Iron, the retina and the lens: a focused review. Exp Eye Res (2010) 0.88
Risk factors and biomarkers of age-related macular degeneration. Prog Retin Eye Res (2016) 0.85
Prevalence of anti-retinal autoantibodies in different stages of Age-related macular degeneration. BMC Ophthalmol (2014) 0.82
Receptor-Mediated Mechanism Controlling Tissue Levels of Bioactive Lipid Oxidation Products. Circ Res (2015) 0.81
Molecular biomarkers in glaucoma. Invest Ophthalmol Vis Sci (2013) 0.81
The proteomics of drusen. Cold Spring Harb Perspect Med (2014) 0.80
The past, present, and future of exudative age-related macular degeneration treatment. Middle East Afr J Ophthalmol (2012) 0.77
Transcriptome changes in age-related macular degeneration. BMC Med (2012) 0.76
An (1)O2 route to γ-hydroxyalkenal phospholipids by vitamin E-induced fragmentation of hydroperoxydiene-derived endoperoxides. Chem Res Toxicol (2011) 0.76
Lack of involvement of CEP adducts in TLR activation and in angiogenesis. PLoS One (2014) 0.76
Lipids, oxidized lipids, oxidation-specific epitopes, and Age-related Macular Degeneration. Biochim Biophys Acta (2016) 0.76
Biological and pathophysiological roles of end-products of DHA oxidation. Biochim Biophys Acta (2016) 0.75
Carboxyethylpyrrole plasma biomarkers in age-related macular degeneration. Drugs Future (2011) 0.75
Carboxyethylpyrroles: From Hypothesis to the Discovery of Biologically Active Natural Products. Chem Res Toxicol (2016) 0.75
Schwann Cell-Mediated Preservation of Vision in Retinal Degenerative Diseases via the Reduction of Oxidative Stress: A Possible Mechanism. Med Hypothesis Discov Innov Ophthalmol (2016) 0.75
Serum levels of lipid metabolites in age-related macular degeneration. FASEB J (2015) 0.75
Complement factor H polymorphism in age-related macular degeneration. Science (2005) 31.10
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol (2001) 21.37
Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol (2004) 18.86
Complement factor H variant increases the risk of age-related macular degeneration. Science (2005) 17.95
Complement factor H polymorphism and age-related macular degeneration. Science (2005) 17.79
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A (2005) 13.44
An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res (2001) 8.38
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet (2006) 8.33
Age-related macular degeneration. N Engl J Med (2008) 7.49
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet (2006) 7.49
HTRA1 promoter polymorphism in wet age-related macular degeneration. Science (2006) 7.12
Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med (2007) 6.47
Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci U S A (2002) 6.47
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet (2005) 6.36
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science (2006) 5.67
Susceptibility genes for age-related maculopathy on chromosome 10q26. Am J Hum Genet (2005) 4.91
Variation in complement factor 3 is associated with risk of age-related macular degeneration. Nat Genet (2007) 4.23
Association between C-reactive protein and age-related macular degeneration. JAMA (2004) 4.16
Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA. Nat Genet (2008) 4.16
Chemistry and metabolism of lipids in the vertebrate retina. Prog Lipid Res (1983) 4.07
Oxidative damage-induced inflammation initiates age-related macular degeneration. Nat Med (2008) 3.92
A prospective study of cigarette smoking and age-related macular degeneration in women. JAMA (1996) 3.79
A potential role for immune complex pathogenesis in drusen formation. Exp Eye Res (2000) 2.58
Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration. J Biol Chem (2003) 2.30
Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration. JAMA (2006) 2.15
Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers. Arch Ophthalmol (2005) 2.08
Increase in the advanced glycation end product pentosidine in Bruch's membrane with age. Invest Ophthalmol Vis Sci (1999) 1.67
Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration. Proc Natl Acad Sci U S A (2006) 1.59
Overview of progress in the epidemiology of age-related macular degeneration. Ophthalmic Epidemiol (2007) 1.52
Advanced glycation end products in age-related macular degeneration. Arch Ophthalmol (1998) 1.51
Retinal pigment epithelium lipofuscin proteomics. Mol Cell Proteomics (2008) 1.50
Oxidatively truncated docosahexaenoate phospholipids: total synthesis, generation, and Peptide adduction chemistry. J Org Chem (2003) 1.49
Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration. Ophthalmology (2005) 1.41
Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis. Ophthalmology (2008) 1.22
C-reactive protein level and risk of aging macula disorder: The Rotterdam Study. Arch Ophthalmol (2007) 1.15
The relation between C reactive protein and age related macular degeneration in the Cardiovascular Health Study. Br J Ophthalmol (2005) 1.03
Role of ocular melanin in ophthalmic physiology and pathology. Photochem Photobiol (2008) 1.02
The LOC387715 polymorphism, inflammatory markers, smoking, and age-related macular degeneration. A population-based case-control study. Ophthalmology (2007) 0.96
Carboxyethylpyrrole adducts, age-related macular degeneration and neovascularization. Adv Exp Med Biol (2008) 0.81
Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci U S A (2002) 6.47
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30
Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype. Nat Med (2007) 4.11
Oxidative damage-induced inflammation initiates age-related macular degeneration. Nat Med (2008) 3.92
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands. Nature (2010) 3.70
Reversible cerebral vasoconstriction syndromes: analysis of 139 cases. Arch Neurol (2011) 3.39
A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. J Biol Chem (2002) 3.17
Paneth cell trypsin is the processing enzyme for human defensin-5. Nat Immunol (2002) 3.13
Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. J Biol Chem (2002) 2.94
Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT). Ophthalmology (2013) 2.82
Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell (2009) 2.63
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components. Nat Med (2012) 2.49
Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation. Nature (2004) 2.48
A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells. J Neurosci (2009) 2.35
The lipid whisker model of the structure of oxidized cell membranes. J Biol Chem (2007) 2.31
Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration. J Biol Chem (2003) 2.30
The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1). J Gen Physiol (2006) 2.18
Factors associated with islet yield and insulin independence after total pancreatectomy and islet cell autotransplantation in patients with chronic pancreatitis utilizing off-site islet isolation: Cleveland Clinic experience. J Clin Endocrinol Metab (2015) 2.14
The nob2 mouse, a null mutation in Cacna1f: anatomical and functional abnormalities in the outer retina and their consequences on ganglion cell visual responses. Vis Neurosci (2006) 2.10
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Invest Ophthalmol Vis Sci (2002) 2.03
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy. Clin Cancer Res (2013) 2.00
Proteomics reveal Cochlin deposits associated with glaucomatous trabecular meshwork. J Biol Chem (2004) 2.00
RESOLUTION OF NONINFECTIOUS UVEITIC CYSTOID MACULAR EDEMA WITH TOPICAL DIFLUPREDNATE. Retina (2017) 1.96
Molecular basis for the redox control of nuclear transport of the structural chromatin protein Hmgb1. Exp Cell Res (2006) 1.82
Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer. Invest Ophthalmol Vis Sci (2002) 1.79
SOD2 knockdown mouse model of early AMD. Invest Ophthalmol Vis Sci (2007) 1.77
Long-term follow-up of type II endoleak embolization reveals the need for close surveillance. J Vasc Surg (2011) 1.72
Neuronal pentraxins mediate synaptic refinement in the developing visual system. J Neurosci (2006) 1.71
Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration. Proc Natl Acad Sci U S A (2006) 1.59
SOX2 mutation causes anophthalmia, hearing loss, and brain anomalies. Am J Med Genet A (2005) 1.59
Formation and progression of sub-retinal pigment epithelium deposits in Efemp1 mutation knock-in mice: a model for the early pathogenic course of macular degeneration. Hum Mol Genet (2007) 1.54
Functional roles of bestrophins in ocular epithelia. Prog Retin Eye Res (2009) 1.52
Retinal pigment epithelium lipofuscin proteomics. Mol Cell Proteomics (2008) 1.50
Oxidatively truncated docosahexaenoate phospholipids: total synthesis, generation, and Peptide adduction chemistry. J Org Chem (2003) 1.49
Mutations in the RPGR gene cause X-linked cone dystrophy. Hum Mol Genet (2002) 1.47
Identification of the gene and the mutation responsible for the mouse nob phenotype. Invest Ophthalmol Vis Sci (2003) 1.47
Lung cancer risk and workplace exposure to environmental tobacco smoke. Am J Public Health (2007) 1.47
Nyctalopin expression in retinal bipolar cells restores visual function in a mouse model of complete X-linked congenital stationary night blindness. J Neurophysiol (2007) 1.46
Expression and localization of bestrophin during normal mouse development. Invest Ophthalmol Vis Sci (2003) 1.45
Bilateral macular lesions in a 10-year-old girl. Am J Ophthalmol (2006) 1.40
Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron (2011) 1.39
LIMITED CARBOHYDRATE REFEEDING INSTRUCTION FOR LONG-TERM WEIGHT MAINTENANCE FOLLOWING A KETOGENIC, VERY-LOW-CALORIE MEAL PLAN. Endocr Pract (2017) 1.39
Elimination of the rho1 subunit abolishes GABA(C) receptor expression and alters visual processing in the mouse retina. J Neurosci (2002) 1.39
Rapid and selective oxygen-regulated protein tyrosine denitration and nitration in mitochondria. J Biol Chem (2004) 1.37
Ocular abnormalities in Large(myd) and Large(vls) mice, spontaneous models for muscle, eye, and brain diseases. Mol Cell Neurosci (2005) 1.33
Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis. Invest Ophthalmol Vis Sci (2006) 1.32
Punctin, a novel ADAMTS-like molecule, ADAMTSL-1, in extracellular matrix. J Biol Chem (2002) 1.31
Temporal properties of the mouse cone electroretinogram. J Neurophysiol (2002) 1.28
Pharmacological studies of the mouse cone electroretinogram. Vis Neurosci (2005) 1.24
Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis. Circ Res (2012) 1.24
Dynamics of protein nitration in cells and mitochondria. Am J Physiol Heart Circ Physiol (2004) 1.24
A model of best vitelliform macular dystrophy in rats. Invest Ophthalmol Vis Sci (2004) 1.23
Immunohistochemical analysis of the outer plexiform layer in the nob mouse shows no abnormalities. Vis Neurosci (2003) 1.23
Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes. Mol Cell Proteomics (2010) 1.22
Evidence that light modulates protein nitration in rat retina. Mol Cell Proteomics (2002) 1.22
Cochlin deposits in the trabecular meshwork of the glaucomatous DBA/2J mouse. Exp Eye Res (2005) 1.20
Light-evoked responses of the mouse retinal pigment epithelium. J Neurophysiol (2003) 1.20
Subretinal implantation of semiconductor-based photodiodes: durability of novel implant designs. J Rehabil Res Dev (2002) 1.20
Intense light exposure changes the crystallin content in retina. Exp Eye Res (2003) 1.20
Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation. J Biol Chem (2010) 1.19
Membrane frizzled-related protein is necessary for the normal development and maintenance of photoreceptor outer segments. Vis Neurosci (2008) 1.18
Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells. Cancer Res (2005) 1.17
Fatal occupational injury rates in southern and non-southern States, by race and Hispanic ethnicity. Am J Public Health (2004) 1.17
Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina. J Neurosci (2012) 1.17
Retinal degeneration in a rodent model of Smith-Lemli-Opitz syndrome: electrophysiologic, biochemical, and morphologic features. Arch Ophthalmol (2004) 1.16
Crystallin distribution in Bruch's membrane-choroid complex from AMD and age-matched donor eyes. Exp Eye Res (2005) 1.16
Conformation of an endogenous ligand in a membrane bilayer for the macrophage scavenger receptor CD36. Biochemistry (2007) 1.16
Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification. Biochemistry (2003) 1.15
Suppression of Ca2+ signaling in a mouse model of Best disease. Hum Mol Genet (2010) 1.14
Interaction between the photoreceptor-specific tubby-like protein 1 and the neuronal-specific GTPase dynamin-1. Invest Ophthalmol Vis Sci (2007) 1.14
Bestrophin interacts physically and functionally with protein phosphatase 2A. J Biol Chem (2002) 1.13
Novel bioactive phospholipids: practical total syntheses of products from the oxidation of arachidonic and linoleic esters of 2-lysophosphatidylcholine(1). J Org Chem (2002) 1.13
Preservation of cardiolipin content during aging in rat heart interfibrillar mitochondria. J Gerontol A Biol Sci Med Sci (2002) 1.12
The Rose-comb mutation in chickens constitutes a structural rearrangement causing both altered comb morphology and defective sperm motility. PLoS Genet (2012) 1.12
Clusterin is present in drusen in age-related macular degeneration. Exp Eye Res (2002) 1.10
A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration. Mol Neurobiol (2010) 1.10
Voltage-dependent calcium channel CaV1.3 subunits regulate the light peak of the electroretinogram. J Neurophysiol (2007) 1.10
Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration. Mol Cell Proteomics (2009) 1.08