Published in JAMA on October 09, 1996
Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci U S A (2002) 6.47
Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study Report Number 3. Ophthalmology (2000) 5.18
Oxidative damage-induced inflammation initiates age-related macular degeneration. Nat Med (2008) 3.92
Age-related macular degeneration. Lancet (2008) 3.34
Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19. Ophthalmology (2005) 3.28
A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions. Am J Hum Genet (2003) 3.23
How big is the burden of visual loss caused by age related macular degeneration in the United Kingdom? Br J Ophthalmol (2003) 3.07
Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables. Invest Ophthalmol Vis Sci (2008) 2.91
Vascular endothelial growth factor in eye disease. Prog Retin Eye Res (2008) 2.73
Tobacco: a medical history. J Urban Health (1999) 2.72
Smoking and age related macular degeneration: the number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation. Br J Ophthalmol (2006) 2.67
Age-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions. Am J Hum Genet (2004) 2.58
Epidemiology of age-related maculopathy: a review. Eur J Epidemiol (2003) 2.32
Comparison of Risk Factor Profiles for Primary Open-Angle Glaucoma Subtypes Defined by Pattern of Visual Field Loss: A Prospective Study. Invest Ophthalmol Vis Sci (2015) 2.13
An update on the genetics of age-related macular degeneration. Mol Vis (2007) 1.95
Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study. Arch Intern Med (2009) 1.83
Smoking, dietary betaine, methionine, and vitamin D in monozygotic twins with discordant macular degeneration: epigenetic implications. Ophthalmology (2011) 1.81
Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors. Ophthalmology (2011) 1.61
28,000 Cases of age related macular degeneration causing visual loss in people aged 75 years and above in the United Kingdom may be attributable to smoking. Br J Ophthalmol (2005) 1.60
Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration. Proc Natl Acad Sci U S A (2006) 1.59
Intakes of Lutein, Zeaxanthin, and Other Carotenoids and Age-Related Macular Degeneration During 2 Decades of Prospective Follow-up. JAMA Ophthalmol (2015) 1.46
Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis. BMJ (2007) 1.46
Guidelines for the management of neovascular age-related macular degeneration by the European Society of Retina Specialists (EURETINA). Br J Ophthalmol (2014) 1.41
Age-Related Macular Degeneration and Coronary Artery Disease in a VA Population. South Med J (2015) 1.40
Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers. Mol Cell Proteomics (2009) 1.39
Animal models of age related macular degeneration. Mol Aspects Med (2012) 1.39
Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration. Invest Ophthalmol Vis Sci (2011) 1.30
Aging is not a disease: distinguishing age-related macular degeneration from aging. Prog Retin Eye Res (2013) 1.29
Associated factors for age related maculopathy in the adult population in China: the Beijing eye study. Br J Ophthalmol (2006) 1.29
HTRA1 variants in exudative age-related macular degeneration and interactions with smoking and CFH. Invest Ophthalmol Vis Sci (2008) 1.28
Multicenter prospective, randomized, double-masked, placebo-controlled study of Rheopheresis to treat nonexudative age-related macular degeneration: interim analysis. Trans Am Ophthalmol Soc (2002) 1.23
Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes. Mol Cell Proteomics (2010) 1.22
Knowledge about cataract, glaucoma, and age related macular degeneration in the Hong Kong Chinese population. Br J Ophthalmol (2002) 1.17
Reduced secretion of fibulin 5 in age-related macular degeneration and cutis laxa. Hum Mutat (2006) 1.17
Body mass index and the incidence of visually significant age-related maculopathy in men. Arch Ophthalmol (2001) 1.17
Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy. Prog Retin Eye Res (2014) 1.17
Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Ophthalmology (2012) 1.16
A new locus for autosomal dominant stargardt-like disease maps to chromosome 4. Am J Hum Genet (1999) 1.15
Genetic susceptibility to age related macular degeneration. J Med Genet (2000) 1.11
A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration. Mol Neurobiol (2010) 1.10
A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration. Invest Ophthalmol Vis Sci (2006) 1.09
Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration. Mol Cell Proteomics (2009) 1.08
Dietary omega-3 fatty acids, other fat intake, genetic susceptibility, and progression to incident geographic atrophy. Ophthalmology (2013) 1.08
Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration. Mol Vis (2010) 1.08
Vision impairment and eye care utilization among Americans 50 and older. Curr Eye Res (2010) 1.06
Lipids, lipoproteins, and age-related macular degeneration. J Lipids (2011) 1.05
Mechanisms for countering oxidative stress and damage in retinal pigment epithelium. Int Rev Cell Mol Biol (2012) 1.05
Progress in defining the molecular biology of age related macular degeneration. Hum Genet (2007) 1.01
Dietary ω-3 fatty acid and fish intake and incident age-related macular degeneration in women. Arch Ophthalmol (2011) 1.00
Prospective study of lutein/zeaxanthin intake and risk of age-related macular degeneration. Am J Clin Nutr (2008) 0.98
Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. Prog Retin Eye Res (2015) 0.98
Smoking and age-related macular degeneration: review and update. J Ophthalmol (2013) 0.97
rs5888 variant of SCARB1 gene is a possible susceptibility factor for age-related macular degeneration. PLoS One (2009) 0.97
Nicotine increases the VEGF/PEDF ratio in retinal pigment epithelium: a possible mechanism for CNV in passive smokers with AMD. Invest Ophthalmol Vis Sci (2011) 0.97
Cigarette smoke-related hydroquinone dysregulates MCP-1, VEGF and PEDF expression in retinal pigment epithelium in vitro and in vivo. PLoS One (2011) 0.96
Combined effects of complement factor H genotypes, fish consumption, and inflammatory markers on long-term risk for age-related macular degeneration in a cohort. Am J Epidemiol (2008) 0.95
Genetics and molecular pathology of Stargardt-like macular degeneration. Prog Retin Eye Res (2010) 0.95
Retinal pigment epithelial acid lipase activity and lipoprotein receptors: effects of dietary omega-3 fatty acids. Trans Am Ophthalmol Soc (2002) 0.95
Risk factors for age-related maculopathy. J Ophthalmol (2009) 0.95
Evaluation of new and established age-related macular degeneration susceptibility genes in the Women's Health Initiative Sight Exam (WHI-SE) Study. Am J Ophthalmol (2011) 0.93
CEP biomarkers as potential tools for monitoring therapeutics. PLoS One (2013) 0.92
Bilateral involvement by age related maculopathy lesions in a population. Br J Ophthalmol (1998) 0.92
Age-related macular degeneration and recent developments: new hope for old eyes? Postgrad Med J (2007) 0.91
Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study. Mol Vis (2010) 0.91
Half a pack of cigarettes a day more than doubles DNA breaks in circulating leukocytes. Tob Induc Dis (2010) 0.91
Recurrent choroidal neovascularization after macular translocation surgery with 360-degree peripheral retinectomy. Retina (2008) 0.91
TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD. BMC Ophthalmol (2007) 0.90
Age-related macular degeneration: a target for nanotechnology derived medicines. Int J Nanomedicine (2007) 0.89
Clinical characteristics and current treatment of age-related macular degeneration. Cold Spring Harb Perspect Med (2014) 0.87
Age-Related Macular Degeneration: Advances in Management and Diagnosis. J Clin Med (2015) 0.87
The prevalence and analysis of risk factors for age-related macular degeneration: 18-year follow-up data from the Speedwell eye study, United Kingdom. Eye (Lond) (2011) 0.86
Race, iris color, and age-related macular degeneration. Trans Am Ophthalmol Soc (2000) 0.86
Regulation of signaling events involved in the pathophysiology of neovascular AMD. Mol Vis (2016) 0.85
Prospective study of common variants in the retinoic acid receptor-related orphan receptor α gene and risk of neovascular age-related macular degeneration. Arch Ophthalmol (2010) 0.85
Age-related macular degeneration: armed against ARMD. CMAJ (2004) 0.85
Age-related macular degeneration. Ulster Med J (2005) 0.84
Peroxisome proliferator-activated receptor and age-related macular degeneration. PPAR Res (2008) 0.84
Age-related macular degeneration and mortality in community-dwelling elders: the age, gene/environment susceptibility Reykjavik study. Ophthalmology (2014) 0.84
Future therapies of wet age-related macular degeneration. J Ophthalmol (2015) 0.84
Structural effects of fibulin 5 missense mutations associated with age-related macular degeneration and cutis laxa. Invest Ophthalmol Vis Sci (2009) 0.83
"Oxidative protector" enzymes in the macular retinal pigment epithelium of aging eyes and eyes with age-related macular degeneration. Trans Am Ophthalmol Soc (1998) 0.82
R102G polymorphism of the C3 gene associated with exudative age-related macular degeneration in a French population. Mol Vis (2010) 0.82
Protective effect of paraoxonase 1 gene variant Gln192Arg in age-related macular degeneration. Am J Ophthalmol (2009) 0.82
[Accumulation of lipid particles in Bruch's membrane of LDL receptor knockout mice as a model of age-related macular degeneration]. Ophthalmologe (2004) 0.82
Does smoking influence the type of age related macular degeneration causing visual impairment? Br J Ophthalmol (2006) 0.82
Neuroprotective effects of nonfeminizing estrogens in retinal photoreceptor neurons. Invest Ophthalmol Vis Sci (2012) 0.81
Prospective study of common variants in CX3CR1 and risk of macular degeneration: pooled analysis from 5 long-term studies. JAMA Ophthalmol (2014) 0.81
Altered retinoid homeostasis catalyzed by a nicotine metabolite: implications in macular degeneration and normal development. Proc Natl Acad Sci U S A (2005) 0.81
Monozygotic twins with polypoidal choroidal vasuculopathy. Clin Ophthalmol (2010) 0.81
Prevalence of age-related macular degeneration among the elderly. Caspian J Intern Med (2015) 0.80
Update on Clinical Trials in Dry Age-related Macular Degeneration. Middle East Afr J Ophthalmol (2016) 0.80
Risk factors for exudative age-related macular degeneration in a large French case-control study. Graefes Arch Clin Exp Ophthalmol (2013) 0.80
Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration. Cell Mol Life Sci (2014) 0.80
The proteomics of drusen. Cold Spring Harb Perspect Med (2014) 0.80
Vitamin E and age-related macular degeneration in a randomized trial of women. Ophthalmology (2010) 0.80
Progress and perspectives on the role of RPE cell inflammatory responses in the development of age-related macular degeneration. J Inflamm Res (2008) 0.80
Harmful effects of nicotine. Indian J Med Paediatr Oncol (2015) 0.79
Influence of arterial hypertension and diet-induced atherosclerosis on macular drusen. Graefes Arch Clin Exp Ophthalmol (2003) 0.79
An association between air pollution and mortality in six U.S. cities. N Engl J Med (1993) 38.84
Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol (1985) 26.13
Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals. Am J Epidemiol (1992) 17.17
Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults. Am J Respir Crit Care Med (1995) 15.80
Observations on recent increase in mortality from asthma. Br Med J (1968) 14.82
Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med (2001) 14.48
The use of estrogens and progestins and the risk of breast cancer in postmenopausal women. N Engl J Med (1995) 11.08
Body weight and mortality among women. N Engl J Med (1995) 11.04
Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol (1989) 10.98
Validation of questionnaire information on risk factors and disease outcomes in a prospective cohort study of women. Am J Epidemiol (1986) 10.84
Validity of self-reported waist and hip circumferences in men and women. Epidemiology (1990) 10.57
Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet (1998) 10.11
Reproducibility and validity of a self-administered physical activity questionnaire. Int J Epidemiol (1994) 9.90
Reproducibility and validity of food intake measurements from a semiquantitative food frequency questionnaire. J Am Diet Assoc (1993) 9.90
Aspirin and the risk of colorectal cancer in women. N Engl J Med (1995) 9.59
Dietary fat and coronary heart disease: a comparison of approaches for adjusting for total energy intake and modeling repeated dietary measurements. Am J Epidemiol (1999) 9.34
Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med (2000) 9.05
Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. N Engl J Med (1990) 8.98
Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the nurses' health study. N Engl J Med (1991) 8.66
Prospective study of alcohol consumption and risk of coronary disease in men. Lancet (1991) 8.64
Test of the National Death Index. Am J Epidemiol (1984) 8.46
Dietary fat intake and the risk of coronary heart disease in women. N Engl J Med (1997) 8.43
Misinterpretation and misuse of the kappa statistic. Am J Epidemiol (1987) 8.29
The Nurses' Health Study: 20-year contribution to the understanding of health among women. J Womens Health (1997) 8.00
Physical activity and incidence of non-insulin-dependent diabetes mellitus in women. Lancet (1991) 7.87
Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med (1995) 7.62
Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men. Diabetes Care (1994) 7.11
Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. JAMA (1998) 7.09
Reproducibility and validity of dietary patterns assessed with a food-frequency questionnaire. Am J Clin Nutr (1999) 7.02
Plasma organochlorine levels and the risk of breast cancer. N Engl J Med (1997) 7.02
Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women. JAMA (1997) 6.92
The effect of fruit and vegetable intake on risk for coronary heart disease. Ann Intern Med (2001) 6.37
Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med (1993) 6.37
Physical activity and television watching in relation to risk for type 2 diabetes mellitus in men. Arch Intern Med (2001) 6.23
Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med (1999) 6.21
Abdominal adiposity and coronary heart disease in women. JAMA (1998) 6.21
Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst (2003) 6.20
Dietary fiber and the risk of colorectal cancer and adenoma in women. N Engl J Med (1999) 6.17
A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction. N Engl J Med (1991) 6.13
A prospective study of family history and the risk of colorectal cancer. N Engl J Med (1994) 6.12
A prospective study of obesity and risk of coronary heart disease in women. N Engl J Med (1990) 6.06
A prospective study of dietary calcium and other nutrients and the risk of symptomatic kidney stones. N Engl J Med (1993) 5.87
Association between dietary patterns and plasma biomarkers of obesity and cardiovascular disease risk. Am J Clin Nutr (2001) 5.67
The assessment of alcohol consumption by a simple self-administered questionnaire. Am J Epidemiol (1991) 5.60
The circumstances preceding death from asthma in young people in 1968 to 1969. Br J Dis Chest (1971) 5.53
Physical activity, obesity, and risk for colon cancer and adenoma in men. Ann Intern Med (1995) 5.42
Aspirin use and the risk for colorectal cancer and adenoma in male health professionals. Ann Intern Med (1994) 5.42
Vitamin E consumption and the risk of coronary disease in women. N Engl J Med (1993) 5.39
Lactation and a reduced risk of premenopausal breast cancer. N Engl J Med (1994) 5.37
Rotating night shifts and risk of breast cancer in women participating in the nurses' health study. J Natl Cancer Inst (2001) 5.33
The use of a self-administered questionnaire to assess diet four years in the past. Am J Epidemiol (1988) 5.32
Tubal ligation, hysterectomy, and risk of ovarian cancer. A prospective study. JAMA (1993) 5.31
A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med (2000) 5.17
Prospective study of major dietary patterns and risk of coronary heart disease in men. Am J Clin Nutr (2000) 5.17
A prospective cohort study of vasectomy and prostate cancer in US men. JAMA (1993) 5.09
Correction of logistic regression relative risk estimates and confidence intervals for systematic within-person measurement error. Stat Med (1989) 5.08
Birthweight as a risk factor for breast cancer. Lancet (1996) 5.05
Intake of trans fatty acids and risk of coronary heart disease among women. Lancet (1993) 5.00
Postmenopausal hormone therapy and mortality. N Engl J Med (1997) 4.96
The relevance in adults of air-flow obstruction, but not of mucus hypersecretion, to mortality from chronic lung disease. Results from 20 years of prospective observation. Am Rev Respir Dis (1983) 4.90
Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol (1997) 4.84
Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk. Am J Epidemiol (2000) 4.83
Dual effects of weight and weight gain on breast cancer risk. JAMA (1997) 4.81
Correction of logistic regression relative risk estimates and confidence intervals for measurement error: the case of multiple covariates measured with error. Am J Epidemiol (1990) 4.80
Dietary fat and fiber in relation to risk of breast cancer. An 8-year follow-up. JAMA (1992) 4.80
Weight, weight change, and coronary heart disease in women. Risk within the 'normal' weight range. JAMA (1995) 4.78
Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women. J Natl Cancer Inst (1998) 4.74
Menopause and the risk of coronary heart disease in women. N Engl J Med (1987) 4.70
Alcohol and breast cancer in women: a pooled analysis of cohort studies. JAMA (1998) 4.65