Published in J Biol Chem on April 14, 2004
Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers. J Exp Med (2005) 3.13
Alterations of cellular bioenergetics in pulmonary artery endothelial cells. Proc Natl Acad Sci U S A (2007) 2.44
S-nitrosylation of peroxiredoxin II E promotes peroxynitrite-mediated tyrosine nitration. Plant Cell (2007) 1.59
Review: Reactive oxygen and nitrogen species and functional adaptation of the placenta. Placenta (2010) 1.48
Peroxiredoxins in plants and cyanobacteria. Antioxid Redox Signal (2011) 1.41
The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal. Arch Biochem Biophys (2008) 1.36
Impaired mitochondrial respiration and protein nitration in the rat hippocampus after acute inhalation of combustion smoke. Toxicol Appl Pharmacol (2008) 1.18
Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: mitochondria as the major target. Biochim Biophys Acta (2008) 1.14
Protein tyrosine nitration of the flavin subunit is associated with oxidative modification of mitochondrial complex II in the post-ischemic myocardium. J Biol Chem (2008) 1.12
Age-related alterations in oxidatively damaged proteins of mouse skeletal muscle mitochondrial electron transport chain complexes. Free Radic Biol Med (2008) 1.08
Protein nitration in placenta - functional significance. Placenta (2008) 1.02
Peroxynitrite mediates active site tyrosine nitration in manganese superoxide dismutase. Evidence of a role for the carbonate radical anion. J Am Chem Soc (2010) 1.00
Novel interactions of mitochondria and reactive oxygen/nitrogen species in alcohol mediated liver disease. World J Gastroenterol (2007) 0.99
Increased protein nitration in mitochondrial diseases: evidence for vessel wall involvement. Mol Cell Proteomics (2010) 0.97
Age-related alterations in oxidatively damaged proteins of mouse heart mitochondrial electron transport chain complexes. Free Radic Biol Med (2008) 0.96
Nitric oxide blocks cellular heme insertion into a broad range of heme proteins. Free Radic Biol Med (2010) 0.96
Tyk2 tyrosine kinase expression is required for the maintenance of mitochondrial respiration in primary pro-B lymphocytes. Mol Cell Biol (2006) 0.95
Angiotensin II inhibits insulin-stimulated GLUT4 translocation and Akt activation through tyrosine nitration-dependent mechanisms. PLoS One (2010) 0.94
Cyclic GMP-independent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: a role for alpha-actinin nitration. Proc Natl Acad Sci U S A (2006) 0.92
Redox-control of matrix metalloproteinase-1: a critical link between free radicals, matrix remodeling and degenerative disease. Respir Physiol Neurobiol (2010) 0.92
Escherichia coli NsrR regulates a pathway for the oxidation of 3-nitrotyramine to 4-hydroxy-3-nitrophenylacetate. J Bacteriol (2008) 0.91
Protein nitrotryptophan: formation, significance and identification. J Proteomics (2011) 0.88
Nitration of the tumor suppressor protein p53 at tyrosine 327 promotes p53 oligomerization and activation. Biochemistry (2010) 0.86
Protein tyrosine nitration in cellular signal transduction pathways. J Recept Signal Transduct Res (2010) 0.85
Selective vulnerability of synaptic signaling and metabolism to nitrosative stress. Antioxid Redox Signal (2012) 0.85
Functional roles of protein nitration in acute and chronic liver diseases. Oxid Med Cell Longev (2014) 0.85
Hypoxia upregulates PGI-synthase and increases PGI₂ release in human vascular cells exposed to inflammatory stimuli. J Lipid Res (2011) 0.85
High-throughput liquid-liquid fractionation of multiple protein post-translational modifications. J Proteome Res (2009) 0.83
A manganese superoxide dismutase (SOD2)-mediated adaptive response. Radiat Res (2012) 0.82
Characterization of a cellular denitrase activity that reverses nitration of cyclooxygenase. Am J Physiol Heart Circ Physiol (2013) 0.81
Pituitary adenoma nitroproteomics: current status and perspectives. Oxid Med Cell Longev (2013) 0.80
Tubulin tyrosine nitration regulates microtubule organization in plant cells. Front Plant Sci (2013) 0.80
Posttranslational modification of Sirt6 activity by peroxynitrite. Free Radic Biol Med (2014) 0.80
Photo-activity induced by amyloidogenesis. Protein Sci (2007) 0.79
Atherosclerosis: A Link Between Lipid Intake and Protein Tyrosine Nitration. Lipid Insights (2008) 0.79
Glucose-mediated tyrosine nitration in adipocytes: targets and consequences. Free Radic Biol Med (2008) 0.79
Interplay between oxidant species and energy metabolism. Redox Biol (2015) 0.78
Nitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2. Biochem J (2012) 0.77
Effects of cigarette smoke on salivary protein tyrosine nitration. Eur J Med Res (2010) 0.76
Evaluation of a method for nitrotyrosine site identification and relative quantitation using a stable isotope-labeled nitrated spike-in standard and high resolution fourier transform MS and MS/MS analysis. Int J Mol Sci (2014) 0.75
Down regulation of NO signaling in Trypanosoma cruzi upon parasite-extracellular matrix interaction: changes in protein modification by nitrosylation and nitration. PLoS Negl Trop Dis (2015) 0.75
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature (2011) 13.53
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med (2013) 9.44
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. N Engl J Med (2013) 8.21
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. JAMA (2005) 6.14
Prognostic value of myeloperoxidase in patients with chest pain. N Engl J Med (2003) 5.89
Protein carbamylation links inflammation, smoking, uremia and atherogenesis. Nat Med (2007) 4.30
Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype. Nat Med (2007) 4.11
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. JAMA (2008) 3.64
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. J Clin Invest (2004) 3.63
Statins, high-density lipoprotein cholesterol, and regression of coronary atherosclerosis. JAMA (2007) 3.25
A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. J Biol Chem (2002) 3.17
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Paneth cell trypsin is the processing enzyme for human defensin-5. Nat Immunol (2002) 3.13
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet (2011) 3.07
Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks. Arterioscler Thromb Vasc Biol (2013) 3.07
A CD36-dependent signaling cascade is necessary for macrophage foam cell formation. Cell Metab (2006) 3.06
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell Metab (2013) 3.01
Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. J Biol Chem (2002) 2.94
Serum myeloperoxidase levels independently predict endothelial dysfunction in humans. Circulation (2004) 2.79
Myeloperoxidase and cardiovascular disease. Arterioscler Thromb Vasc Biol (2005) 2.77
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells. J Exp Med (2006) 2.51
The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction. Nat Struct Mol Biol (2007) 2.47
Alterations of cellular bioenergetics in pulmonary artery endothelial cells. Proc Natl Acad Sci U S A (2007) 2.44
Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension. FASEB J (2004) 2.37
Diminished global arginine bioavailability and increased arginine catabolism as metabolic profile of increased cardiovascular risk. J Am Coll Cardiol (2009) 2.35
The lipid whisker model of the structure of oxidized cell membranes. J Biol Chem (2007) 2.31
Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration. J Biol Chem (2003) 2.30
Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase. J Biol Chem (2004) 2.28
Effect of plasma uric acid on antioxidant capacity, oxidative stress, and insulin sensitivity in obese subjects. Diabetes (2013) 2.25
Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol (2007) 2.22
Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: a preventive cardiology information system (PreCIS) database cohort study. Arthritis Rheum (2008) 2.19
Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy. JAMA (2003) 2.16
Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide. Eur Heart J (2014) 2.08
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Invest Ophthalmol Vis Sci (2002) 2.03
Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation. J Biol Chem (2002) 2.02
Proteomics reveal Cochlin deposits associated with glaucomatous trabecular meshwork. J Biol Chem (2004) 2.00
Oxidative and nitrosative events in asthma. Free Radic Biol Med (2003) 1.97
p53 is a suppressor of inflammatory response in mice. FASEB J (2005) 1.91
Novel mechanism of activation of NADPH oxidase 5. calcium sensitization via phosphorylation. J Biol Chem (2006) 1.90
Concurrent evaluation of novel cardiac biomarkers in acute coronary syndrome: myeloperoxidase and soluble CD40 ligand and the risk of recurrent ischaemic events in TACTICS-TIMI 18. Eur Heart J (2008) 1.88
Association between four SNPs on chromosome 9p21 and myocardial infarction is replicated in an Italian population. J Hum Genet (2007) 1.87
Relationship between cardiovascular risk factors and atherosclerotic disease burden measured by intravascular ultrasound. J Am Coll Cardiol (2006) 1.87
Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure. Eur Heart J (2008) 1.85
An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med (2012) 1.85
Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction. Circulation (2007) 1.85
Coronary artery calcification and changes in atheroma burden in response to established medical therapies. J Am Coll Cardiol (2006) 1.84
Molecular basis for the redox control of nuclear transport of the structural chromatin protein Hmgb1. Exp Cell Res (2006) 1.82
Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages. J Biol Chem (2004) 1.80
SOD2 knockdown mouse model of early AMD. Invest Ophthalmol Vis Sci (2007) 1.77
Plasma myeloperoxidase predicts incident cardiovascular risks in stable patients undergoing medical management for coronary artery disease. Clin Chem (2010) 1.74
Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma. Am J Respir Crit Care Med (2005) 1.72
High-density lipoprotein function, dysfunction, and reverse cholesterol transport. Arterioscler Thromb Vasc Biol (2012) 1.70
Levels of soluble endothelium-derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality. Br J Haematol (2005) 1.69
Statins promote potent systemic antioxidant effects through specific inflammatory pathways. Circulation (2003) 1.69
Pulmonary hypertension associated with advanced systolic heart failure: dysregulated arginine metabolism and importance of compensatory dimethylarginine dimethylaminohydrolase-1. J Am Coll Cardiol (2012) 1.69
Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation. Am J Physiol Lung Cell Mol Physiol (2004) 1.68
Effects of native and myeloperoxidase-modified apolipoprotein a-I on reverse cholesterol transport and atherosclerosis in mice. Arterioscler Thromb Vasc Biol (2014) 1.66
Prognostic value and echocardiographic determinants of plasma myeloperoxidase levels in chronic heart failure. J Am Coll Cardiol (2007) 1.66
Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III. J Biol Chem (2002) 1.63
Myeloperoxidase and plasminogen activator inhibitor 1 play a central role in ventricular remodeling after myocardial infarction. J Exp Med (2003) 1.59
Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration. Proc Natl Acad Sci U S A (2006) 1.59
The contributory role of gut microbiota in cardiovascular disease. J Clin Invest (2014) 1.57
Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity. Am J Pathol (2005) 1.56
Identification of alpha-chloro fatty aldehydes and unsaturated lysophosphatidylcholine molecular species in human atherosclerotic lesions. Circulation (2003) 1.55
Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography. Circ Cardiovasc Genet (2012) 1.54
Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. J Lipid Res (2010) 1.53
Modification of high density lipoprotein by myeloperoxidase generates a pro-inflammatory particle. J Biol Chem (2009) 1.51
Tetrahydrobiopterin radical enzymology. Chem Rev (2003) 1.50
Retinal pigment epithelium lipofuscin proteomics. Mol Cell Proteomics (2008) 1.50
Oxidatively truncated docosahexaenoate phospholipids: total synthesis, generation, and Peptide adduction chemistry. J Org Chem (2003) 1.49
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. Nat Med (2010) 1.49
An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction. Am J Hum Genet (2007) 1.48
Formation of dysfunctional high-density lipoprotein by myeloperoxidase. Trends Cardiovasc Med (2005) 1.47
Emerging role of myeloperoxidase and oxidant stress markers in cardiovascular risk assessment. Curr Opin Lipidol (2003) 1.46
Serum myeloperoxidase and mortality in maintenance hemodialysis patients. Am J Kidney Dis (2006) 1.44
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition. Arterioscler Thromb Vasc Biol (2009) 1.44
Immunoglobulins against tyrosine-nitrated epitopes in coronary artery disease. Circulation (2012) 1.42
Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after myocardial infarction. Circulation (2005) 1.42
Bacterial nitric-oxide synthases operate without a dedicated redox partner. J Biol Chem (2008) 1.41
Direct evidence for nitric oxide production by a nitric-oxide synthase-like protein from Bacillus subtilis. J Biol Chem (2002) 1.41
Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertension. Blood (2012) 1.40
Increased carotid intima media thickness and cardiac biomarkers in HIV infected children. AIDS (2007) 1.40