Published in EMBO J on February 19, 2009
The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA. Science (2009) 4.42
The mechanism for activation of GTP hydrolysis on the ribosome. Science (2010) 4.05
What recent ribosome structures have revealed about the mechanism of translation. Nature (2009) 4.01
High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy. Ultramicroscopy (2013) 3.24
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature (2010) 2.85
Iterative stable alignment and clustering of 2D transmission electron microscope images. Structure (2012) 2.07
Accommodation of aminoacyl-tRNA into the ribosome involves reversible excursions along multiple pathways. RNA (2010) 1.91
A new understanding of the decoding principle on the ribosome. Nature (2012) 1.88
Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation. Science (2013) 1.84
Structure and dynamics of a processive Brownian motor: the translating ribosome. Annu Rev Biochem (2010) 1.84
Likelihood-based classification of cryo-EM images using FREALIGN. J Struct Biol (2013) 1.72
Single-particle reconstruction of biological macromolecules in electron microscopy--30 years. Q Rev Biophys (2009) 1.61
Exploring conformational modes of macromolecular assemblies by multiparticle cryo-EM. Curr Opin Struct Biol (2009) 1.60
Identifying conformational states of macromolecules by eigen-analysis of resampled cryo-EM images. Structure (2011) 1.53
Conformational sampling of aminoacyl-tRNA during selection on the bacterial ribosome. J Mol Biol (2010) 1.47
Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu. Q Rev Biophys (2009) 1.45
IRES-induced conformational changes in the ribosome and the mechanism of translation initiation by internal ribosomal entry. Biochim Biophys Acta (2009) 1.34
Evolutionary optimization of speed and accuracy of decoding on the ribosome. Philos Trans R Soc Lond B Biol Sci (2011) 1.30
Fundamentals of three-dimensional reconstruction from projections. Methods Enzymol (2010) 1.30
Modeling protein structure at near atomic resolutions with Gorgon. J Struct Biol (2011) 1.29
Structure and dynamics of the mammalian ribosomal pretranslocation complex. Mol Cell (2011) 1.28
Decoding in the absence of a codon by tmRNA and SmpB in the ribosome. Science (2012) 1.24
Structure of EF-G-ribosome complex in a pretranslocation state. Nat Struct Mol Biol (2013) 1.20
Biological mechanisms, one molecule at a time. Genes Dev (2011) 1.19
Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome. Proc Natl Acad Sci U S A (2011) 1.18
Missense suppressor mutations in 16S rRNA reveal the importance of helices h8 and h14 in aminoacyl-tRNA selection. RNA (2010) 1.16
Reaching the information limit in cryo-EM of biological macromolecules: experimental aspects. Biophys J (2011) 1.14
Optimization of speed and accuracy of decoding in translation. EMBO J (2010) 1.13
The complex of tmRNA-SmpB and EF-G on translocating ribosomes. Nature (2012) 1.09
A structural view on the mechanism of the ribosome-catalyzed peptide bond formation. Biochim Biophys Acta (2009) 1.08
Dynamics of the translational machinery. Curr Opin Struct Biol (2011) 1.08
Regulation of the mammalian elongation cycle by subunit rolling: a eukaryotic-specific ribosome rearrangement. Cell (2014) 1.08
Structural insights into cognate versus near-cognate discrimination during decoding. EMBO J (2011) 1.07
Molecular dynamics of EF-G during translocation. Proteins (2011) 1.07
Conformational changes in switch I of EF-G drive its directional cycling on and off the ribosome. EMBO J (2009) 1.05
Structural snapshots of actively translating human ribosomes. Cell (2015) 1.05
Accommodation of tmRNA-SmpB into stalled ribosomes: a cryo-EM study. RNA (2009) 1.04
Problems in obtaining perfect images by single-particle electron cryomicroscopy of biological structures in amorphous ice. Microscopy (Oxf) (2013) 1.04
Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation. Nat Chem Biol (2010) 1.01
Structural insights into initial and intermediate steps of the ribosome-recycling process. EMBO J (2012) 0.99
Macromolecular structure modeling from 3D EM using VolRover 2.0. Biopolymers (2012) 0.99
Functional analysis of the uL11 protein impact on translational machinery. Cell Cycle (2016) 0.98
Cryo-electron microscopy modeling by the molecular dynamics flexible fitting method. Biopolymers (2012) 0.98
Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts. Proc Natl Acad Sci U S A (2010) 0.97
Functional role of the sarcin-ricin loop of the 23S rRNA in the elongation cycle of protein synthesis. J Mol Biol (2012) 0.96
Gorgon and pathwalking: macromolecular modeling tools for subnanometer resolution density maps. Biopolymers (2012) 0.96
Comparison of Segger and other methods for segmentation and rigid-body docking of molecular components in cryo-EM density maps. Biopolymers (2012) 0.96
Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A. Mol Cell (2015) 0.94
Helix 69 in 23S rRNA modulates decoding by wild type and suppressor tRNAs. Mol Genet Genomics (2009) 0.94
A highly purified, fluorescently labeled in vitro translation system for single-molecule studies of protein synthesis. Methods Enzymol (2010) 0.92
Addressing open questions about phosphate hydrolysis pathways by careful free energy mapping. J Phys Chem B (2012) 0.92
Constructing and validating initial Cα models from subnanometer resolution density maps with pathwalking. Structure (2012) 0.92
Examinations of tRNA Range of Motion Using Simulations of Cryo-EM Microscopy and X-Ray Data. J Biophys (2011) 0.92
Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits. EMBO J (2010) 0.91
Ribosome-induced tuning of GTP hydrolysis by a translational GTPase. Proc Natl Acad Sci U S A (2014) 0.91
Conformations of macromolecules and their complexes from heterogeneous datasets. Philos Trans R Soc Lond B Biol Sci (2014) 0.90
Potential for interdependent development of tRNA determinants for aminoacylation and ribosome decoding. Nat Commun (2011) 0.90
Ribosome engineering to promote new crystal forms. Acta Crystallogr D Biol Crystallogr (2012) 0.90
Unravelling biological macromolecules with cryo-electron microscopy. Nature (2016) 0.89
Selenocysteine insertion sequence (SECIS)-binding protein 2 alters conformational dynamics of residues involved in tRNA accommodation in 80 S ribosomes. J Biol Chem (2012) 0.88
Natural amino acids do not require their native tRNAs for efficient selection by the ribosome. Nat Chem Biol (2009) 0.88
Functional elucidation of a key contact between tRNA and the large ribosomal subunit rRNA during decoding. RNA (2010) 0.88
Cleavage of the sarcin-ricin loop of 23S rRNA differentially affects EF-G and EF-Tu binding. Nucleic Acids Res (2010) 0.87
Distortion of tRNA upon near-cognate codon recognition on the ribosome. J Biol Chem (2011) 0.87
Molecular basis for RNA polymerization by Qβ replicase. Nat Struct Mol Biol (2012) 0.86
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association. Sci Adv (2016) 0.85
ATTRACT-EM: a new method for the computational assembly of large molecular machines using cryo-EM maps. PLoS One (2012) 0.85
Mutations in the intersubunit bridge regions of 16S rRNA affect decoding and subunit-subunit interactions on the 70S ribosome. Nucleic Acids Res (2010) 0.84
The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis. Nucleic Acids Res (2016) 0.84
Deducing the kinetics of protein synthesis in vivo from the transition rates measured in vitro. PLoS Comput Biol (2014) 0.83
A conserved proline switch on the ribosome facilitates the recruitment and binding of trGTPases. Nat Struct Mol Biol (2012) 0.83
Properties of Escherichia coli EF-Tu mutants designed for fluorescence resonance energy transfer from tRNA molecules. Protein Eng Des Sel (2010) 0.82
Long-range signalling in activation of the translational GTPase EF-Tu. EMBO J (2009) 0.82
Direct evidence of an elongation factor-Tu/Ts·GTP·Aminoacyl-tRNA quaternary complex. J Biol Chem (2014) 0.80
Biochemical aspects of bacterial strategies for handling the incomplete translation processes. Front Microbiol (2014) 0.80
Interaction of tRNA with eukaryotic ribosome. Int J Mol Sci (2015) 0.80
Structural Insights into tRNA Dynamics on the Ribosome. Int J Mol Sci (2015) 0.79
The translation elongation cycle-capturing multiple states by cryo-electron microscopy. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
Review: Translational GTPases. Biopolymers (2016) 0.79
Codon-dependent tRNA fluctuations monitored with fluorescence polarization. Biophys J (2010) 0.78
Phenotypic Suppression of Streptomycin Resistance by Mutations in Multiple Components of the Translation Apparatus. J Bacteriol (2015) 0.77
Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome. Proc Natl Acad Sci U S A (2016) 0.77
Structures and functions of Qβ replicase: translation factors beyond protein synthesis. Int J Mol Sci (2014) 0.77
Labeled EF-Tus for rapid kinetic studies of pretranslocation complex formation. ACS Chem Biol (2014) 0.77
Functional replacement of two highly conserved tetraloops in the bacterial ribosome. Biochemistry (2012) 0.77
From DNA to proteins via the ribosome: structural insights into the workings of the translation machinery. Hum Genomics (2010) 0.76
Nhs: network-based hierarchical segmentation for cryo-electron microscopy density maps. Biopolymers (2012) 0.76
Molecular dynamics of ribosomal elongation factors G and Tu. Eur Biophys J (2010) 0.76
Structural Study of Heterogeneous Biological Samples by Cryoelectron Microscopy and Image Processing. Biomed Res Int (2017) 0.75
Tracking fluctuation hotspots on the yeast ribosome through the elongation cycle. Nucleic Acids Res (2017) 0.75
UCSF Chimera--a visualization system for exploratory research and analysis. J Comput Chem (2004) 112.47
SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol (1996) 22.89
Crystal structure of the ribosome at 5.5 A resolution. Science (2001) 18.21
Structure of the 70S ribosome complexed with mRNA and tRNA. Science (2006) 12.25
Structure of yeast phenylalanine tRNA at 3 A resolution. Nature (1974) 10.27
Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science (2001) 8.68
Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog. Science (1995) 7.39
Intermediate states in the movement of transfer RNA in the ribosome. Nature (1989) 7.30
Situs: A package for docking crystal structures into low-resolution maps from electron microscopy. J Struct Biol (1999) 5.71
Selection of tRNA by the ribosome requires a transition from an open to a closed form. Cell (2002) 5.62
Structural insights into translational fidelity. Annu Rev Biochem (2005) 4.97
Tryptophan transfer RNA as the UGA suppressor. J Mol Biol (1971) 4.90
tRNA selection and kinetic proofreading in translation. Nat Struct Mol Biol (2004) 4.54
Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA. Nature (1988) 4.53
Ribosome structure and the mechanism of translation. Cell (2002) 4.53
Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy. Nat Struct Biol (2003) 3.77
Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process. EMBO J (2002) 3.57
An active role for tRNA in decoding beyond codon:anticodon pairing. Science (2005) 3.49
Crystal structure of active elongation factor Tu reveals major domain rearrangements. Nature (1993) 3.26
Fidelity of aminoacyl-tRNA selection on the ribosome: kinetic and structural mechanisms. Annu Rev Biochem (2001) 2.97
Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Mol Cell (2007) 2.62
Crystal structures of the ribosome in complex with release factors RF1 and RF2 bound to a cognate stop codon. Cell (2005) 2.46
Visualization of elongation factor Tu on the Escherichia coli ribosome. Nature (1997) 2.41
Evidence that the G2661 region of 23S rRNA is located at the ribosomal binding sites of both elongation factors. Biochimie (1987) 2.36
Structure of the ribosome-bound cricket paralysis virus IRES RNA. Nat Struct Mol Biol (2006) 2.32
Transient conformational states of aminoacyl-tRNA during ribosome binding catalyzed by elongation factor Tu. Biochemistry (1994) 2.24
Ribosome interactions of aminoacyl-tRNA and elongation factor Tu in the codon-recognition complex. Nat Struct Biol (2002) 2.24
Essential role of histidine 84 in elongation factor Tu for the chemical step of GTP hydrolysis on the ribosome. J Mol Biol (2003) 2.14
A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation. J Struct Biol (2006) 1.95
Translation at the single-molecule level. Annu Rev Biochem (2008) 1.87
An alpha to beta conformational switch in EF-Tu. Structure (1996) 1.83
Deletion of a conserved, central ribosomal intersubunit RNA bridge. Mol Cell (2006) 1.80
Structural dynamics of the ribosome. Curr Opin Chem Biol (2008) 1.79
Structure of keyhole limpet hemocyanin type 1 (KLH1) at 15 A resolution by electron cryomicroscopy and angular reconstitution. J Mol Biol (1997) 1.75
The role of fluctuations in tRNA selection by the ribosome. Proc Natl Acad Sci U S A (2007) 1.69
Codon-dependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome. EMBO J (1995) 1.67
The role of tRNA as a molecular spring in decoding, accommodation, and peptidyl transfer. FEBS Lett (2005) 1.52
A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nat Struct Mol Biol (2008) 1.50
Intact aminoacyl-tRNA is required to trigger GTP hydrolysis by elongation factor Tu on the ribosome. Biochemistry (2000) 1.47
Conformational change of elongation factor Tu (EF-Tu) induced by antibiotic binding. Crystal structure of the complex between EF-Tu.GDP and aurodox. J Biol Chem (2001) 1.45
Elongation factors in protein biosynthesis. Trends Biochem Sci (2003) 1.39
Mutational analysis reveals two independent molecular requirements during transfer RNA selection on the ribosome. Nat Struct Mol Biol (2006) 1.33
Delayed release of inorganic phosphate from elongation factor Tu following GTP hydrolysis on the ribosome. Biochemistry (2006) 1.30
Effects of the mutation glycine-222----aspartic acid on the functions of elongation factor Tu. Biochemistry (1987) 1.22
Site-directed mutagenesis of Thermus thermophilus elongation factor Tu. Replacement of His85, Asp81 and Arg300. Eur J Biochem (1995) 1.13
Relevance of histidine-84 in the elongation factor Tu GTPase activity and in poly(Phe) synthesis: its substitution by glutamine and alanine. FEBS Lett (1995) 1.11
A single amino acid substitution in elongation factor Tu disrupts interaction between the ternary complex and the ribosome. J Bacteriol (1993) 1.09
A signal relay between ribosomal protein S12 and elongation factor EF-Tu during decoding of mRNA. RNA (2008) 1.02
Regulatory GTPases. Curr Opin Struct Biol (1995) 0.99
Enacyloxin IIa pinpoints a binding pocket of elongation factor Tu for development of novel antibiotics. J Biol Chem (2005) 0.87
Structure of the 30S ribosomal subunit. Nature (2000) 23.11
A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations. J Comput Chem (2003) 15.88
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell (2006) 15.16
Integrated genomic characterization of endometrial carcinoma. Nature (2013) 14.29
Structure of the 70S ribosome complexed with mRNA and tRNA. Science (2006) 12.25
The somatic genomic landscape of glioblastoma. Cell (2013) 11.73
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature (2000) 11.30
Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet (2010) 10.75
The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health (2009) 9.79
Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell (2002) 9.13
Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science (2001) 8.68
Effect of PCI on quality of life in patients with stable coronary disease. N Engl J Med (2008) 7.75
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe (2007) 7.34
Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J Clin Invest (2009) 7.09
Probabilistic Boolean Networks: a rule-based uncertainty model for gene regulatory networks. Bioinformatics (2002) 6.90
Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer. JAMA (2011) 6.81
Pten regulates neuronal arborization and social interaction in mice. Neuron (2006) 6.11
SCAN: SNP and copy number annotation. Bioinformatics (2009) 5.96
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med (2015) 5.71
Selection of tRNA by the ribosome requires a transition from an open to a closed form. Cell (2002) 5.62
Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature (2001) 5.51
Structural insights into translational fidelity. Annu Rev Biochem (2005) 4.97
The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell (2000) 4.82
The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity. Sci Transl Med (2010) 4.78
SPARX, a new environment for Cryo-EM image processing. J Struct Biol (2006) 4.66
Sequence and analysis of rice chromosome 4. Nature (2002) 4.39
A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity. Proc Natl Acad Sci U S A (2007) 4.35
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
The structure of the ribosome with elongation factor G trapped in the posttranslocational state. Science (2009) 4.26
Concern Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation (2002) 4.16
Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia. J Clin Invest (2006) 4.06
What recent ribosome structures have revealed about the mechanism of translation. Nature (2009) 4.01
Sexual orientation and suicidality: a co-twin control study in adult men. Arch Gen Psychiatry (1999) 3.97
Insights into translational termination from the structure of RF2 bound to the ribosome. Science (2008) 3.89
Stargazin modulates AMPA receptor gating and trafficking by distinct domains. Nature (2005) 3.88
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell (2008) 3.87
Structure of the immature dengue virus at low pH primes proteolytic maturation. Science (2008) 3.86
Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 S RNA. J Mol Biol (2002) 3.76
A detailed view of a ribosomal active site: the structure of the L11-RNA complex. Cell (1999) 3.70
Variation in virulence among clades of Escherichia coli O157:H7 associated with disease outbreaks. Proc Natl Acad Sci U S A (2008) 3.69
Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. EMBO J (2004) 3.69
Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism. Lancet Neurol (2008) 3.67
Conformational changes of the flavivirus E glycoprotein. Structure (2004) 3.66
Shell-isolated nanoparticle-enhanced Raman spectroscopy. Nature (2010) 3.64
A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors. Cancer Res (2004) 3.63
Structures of immature flavivirus particles. EMBO J (2003) 3.62
Crystal structure of an initiation factor bound to the 30S ribosomal subunit. Science (2001) 3.51
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome. Mol Cell (2007) 3.44
Genetic architecture of transcript-level variation in humans. Am J Hum Genet (2008) 3.36
Structure of the signal recognition particle interacting with the elongation-arrested ribosome. Nature (2004) 3.31
Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. Nature (2013) 3.27
Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome. Nat Struct Mol Biol (2009) 3.25
Relation of hospital volume to colostomy rates and survival for patients with rectal cancer. J Natl Cancer Inst (2003) 3.21
Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution. Nature (1999) 3.12
Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Nat Genet (2010) 3.02
Structure of monomeric yeast and mammalian Sec61 complexes interacting with the translating ribosome. Science (2009) 3.00
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature (2013) 3.00
Precise segmental renal artery clamping under the guidance of dual-source computed tomography angiography during laparoscopic partial nephrectomy. Eur Urol (2012) 2.95
High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma. J Clin Oncol (2008) 2.92
Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. J Neurosci (2009) 2.90
Structural insight into nascent polypeptide chain-mediated translational stalling. Science (2009) 2.89
Functional architecture of RNA polymerase I. Cell (2007) 2.86
Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a systematic review and meta-analysis. Eur J Cancer (2009) 2.85
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature (2010) 2.85
Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. PLoS One (2009) 2.79
Insights into the decoding mechanism from recent ribosome structures. Trends Biochem Sci (2003) 2.71
Nitrogen fixation island and rhizosphere competence traits in the genome of root-associated Pseudomonas stutzeri A1501. Proc Natl Acad Sci U S A (2008) 2.70
Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism. J Cell Biol (2006) 2.68
Quantized anomalous Hall effect in magnetic topological insulators. Science (2010) 2.67
Visualizing tmRNA entry into a stalled ribosome. Science (2003) 2.67
The mechanical behaviors of polytetrafluorethylene/Al/W energetic composites. J Phys Condens Matter (2009) 2.64
Electron crystallography reveals the structure of metarhodopsin I. EMBO J (2004) 2.63
Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Mol Cell (2007) 2.62
Blocking Scn10a channels in heart reduces late sodium current and is antiarrhythmic. Circ Res (2012) 2.61
Faster STORM using compressed sensing. Nat Methods (2012) 2.61
Trends in prevalence, awareness, management, and control of hypertension among United States adults, 1999 to 2010. J Am Coll Cardiol (2012) 2.57
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res (2013) 2.57
Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis. PLoS One (2011) 2.57
Preclinical properties of 18F-AV-45: a PET agent for Abeta plaques in the brain. J Nucl Med (2009) 2.51
Crystal structures of the ribosome in complex with release factors RF1 and RF2 bound to a cognate stop codon. Cell (2005) 2.46
Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly. Nat Biotechnol (2011) 2.45
A complete mapping of the proteins in the small ribosomal subunit of Escherichia coli. Science (1987) 2.43
Systematic review and meta-analysis of circulatory disease from exposure to low-level ionizing radiation and estimates of potential population mortality risks. Environ Health Perspect (2012) 2.42
Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas. Proc Natl Acad Sci U S A (2007) 2.38
Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol Cell (2008) 2.37